ATE279418T1 - Antidepressive indoltetrahydropyridin-derivate von 2,3-dihydro-7h(1,4)dioxino(2,3-e)indol - Google Patents

Antidepressive indoltetrahydropyridin-derivate von 2,3-dihydro-7h(1,4)dioxino(2,3-e)indol

Info

Publication number
ATE279418T1
ATE279418T1 AT02728990T AT02728990T ATE279418T1 AT E279418 T1 ATE279418 T1 AT E279418T1 AT 02728990 T AT02728990 T AT 02728990T AT 02728990 T AT02728990 T AT 02728990T AT E279418 T1 ATE279418 T1 AT E279418T1
Authority
AT
Austria
Prior art keywords
indoltetrahydropyridine
antidepressive
dioxino
indole
dihydro
Prior art date
Application number
AT02728990T
Other languages
English (en)
Inventor
Gary Paul Stack
Megan Tran
Byron Abel Bravo
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE279418T1 publication Critical patent/ATE279418T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02728990T 2001-04-26 2002-04-25 Antidepressive indoltetrahydropyridin-derivate von 2,3-dihydro-7h(1,4)dioxino(2,3-e)indol ATE279418T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28657501P 2001-04-26 2001-04-26
PCT/US2002/013118 WO2002088146A2 (en) 2001-04-26 2002-04-25 ANTIDEPRESSANT INDOLETETRAHYDROPYRIDINE DERIVATIVES OF 2,3-DIHYDRO-7H-[1,4]DIOXINO[2,3-e]INDOLE

Publications (1)

Publication Number Publication Date
ATE279418T1 true ATE279418T1 (de) 2004-10-15

Family

ID=23099224

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02728990T ATE279418T1 (de) 2001-04-26 2002-04-25 Antidepressive indoltetrahydropyridin-derivate von 2,3-dihydro-7h(1,4)dioxino(2,3-e)indol

Country Status (14)

Country Link
US (1) US6593350B2 (de)
EP (1) EP1381615B1 (de)
JP (1) JP2004533437A (de)
CN (1) CN1267438C (de)
AT (1) ATE279418T1 (de)
AU (1) AU2002259010A1 (de)
BR (1) BR0209336A (de)
CA (1) CA2445583A1 (de)
DE (1) DE60201592T2 (de)
DK (1) DK1381615T3 (de)
ES (1) ES2230490T3 (de)
MX (1) MXPA03009739A (de)
PT (1) PT1381615E (de)
WO (1) WO2002088146A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6939877B2 (en) * 2002-09-12 2005-09-06 Wyeth Antidepressant piperidine derivatives of heterocycle-fused benzodioxans
US20040192730A1 (en) * 2003-03-13 2004-09-30 Dynogen Pharmaceuticals, Inc. Methods of using compounds with combined 5-HT1A and SSRI activities as-needed to treat sexual dysfunction
CN100402534C (zh) * 2006-11-09 2008-07-16 东南大学 一种三环类化合物及其在制药中的应用
DK2442809T3 (en) 2009-06-17 2016-12-19 Vertex Pharma Inhibitors of the replication of influenza virus
AU2011343642A1 (en) 2010-12-16 2013-05-02 Vertex Pharmaceuticals Incorporated Inhibitors of influenza viruses replication
CN102178056B (zh) * 2011-05-05 2012-08-08 王宏雁 二氢吡啶包合物
UA118010C2 (uk) 2011-08-01 2018-11-12 Вертекс Фармасьютікалз Інкорпорейтед Інгібітори реплікації вірусів грипу
EP3068776B1 (de) 2013-11-13 2019-05-29 Vertex Pharmaceuticals Incorporated Hemmer der influenzavirenreplikation
RS57541B1 (sr) 2013-11-13 2018-10-31 Vertex Pharma Postupci za pripremu inhibitora replikacije virusa gripa
MA42422A (fr) 2015-05-13 2018-05-23 Vertex Pharma Inhibiteurs de la réplication des virus de la grippe
JP6704416B2 (ja) 2015-05-13 2020-06-03 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ インフルエンザウイルスの複製の阻害剤を調製する方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639536B2 (en) 1990-03-15 1993-07-29 Pharmacia & Upjohn Company Therapeutically useful heterocyclic indole compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE4140540A1 (de) 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
US5741789A (en) 1995-01-17 1998-04-21 Eli Lilly And Company Compounds having effects on serotonin-related systems
GB9526495D0 (en) 1995-12-23 1996-02-28 Knoll Ag Therapeutic agents
US5869490A (en) 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
GB9627005D0 (en) 1996-12-27 1997-02-12 Knoll Ag Therapeutic agents
GB9704948D0 (en) 1997-03-11 1997-04-30 Knoll Ag Therapeutic agents
US6458802B1 (en) * 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline

Also Published As

Publication number Publication date
WO2002088146A2 (en) 2002-11-07
JP2004533437A (ja) 2004-11-04
ES2230490T3 (es) 2005-05-01
EP1381615B1 (de) 2004-10-13
US6593350B2 (en) 2003-07-15
WO2002088146A3 (en) 2003-02-13
PT1381615E (pt) 2005-02-28
AU2002259010A1 (en) 2002-11-11
DE60201592T2 (de) 2005-02-17
BR0209336A (pt) 2004-06-15
CN1267438C (zh) 2006-08-02
EP1381615A2 (de) 2004-01-21
CN1503800A (zh) 2004-06-09
CA2445583A1 (en) 2002-11-07
MXPA03009739A (es) 2005-03-07
US20020183352A1 (en) 2002-12-05
DK1381615T3 (da) 2004-11-29
DE60201592D1 (de) 2004-11-18

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