ATE279440T1 - Wachstumshormonsekretionsförderer rezeptorfamilie - Google Patents

Wachstumshormonsekretionsförderer rezeptorfamilie

Info

Publication number
ATE279440T1
ATE279440T1 AT96945183T AT96945183T ATE279440T1 AT E279440 T1 ATE279440 T1 AT E279440T1 AT 96945183 T AT96945183 T AT 96945183T AT 96945183 T AT96945183 T AT 96945183T AT E279440 T1 ATE279440 T1 AT E279440T1
Authority
AT
Austria
Prior art keywords
growth hormone
receptors
receptor family
hormone secretion
hormone secretagogue
Prior art date
Application number
AT96945183T
Other languages
English (en)
Inventor
Joseph P Arena
Doris F Cully
Scott D Feighner
Andrew D Howard
Paul A Liberator
James M Schaeffer
Der Ploeg Leonardus Van
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE279440T1 publication Critical patent/ATE279440T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT96945183T 1995-12-13 1996-12-10 Wachstumshormonsekretionsförderer rezeptorfamilie ATE279440T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US858295P 1995-12-13 1995-12-13
US1896296P 1996-06-06 1996-06-06
PCT/US1996/019445 WO1997021730A1 (en) 1995-12-13 1996-12-10 Growth hormone secretagogue receptor family

Publications (1)

Publication Number Publication Date
ATE279440T1 true ATE279440T1 (de) 2004-10-15

Family

ID=26678344

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96945183T ATE279440T1 (de) 1995-12-13 1996-12-10 Wachstumshormonsekretionsförderer rezeptorfamilie

Country Status (7)

Country Link
EP (1) EP0876402B1 (de)
JP (1) JP3754084B2 (de)
AT (1) ATE279440T1 (de)
CA (1) CA2240427C (de)
DE (1) DE69633637T2 (de)
ES (1) ES2229289T3 (de)
WO (1) WO1997021730A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002522058A (ja) 1998-08-10 2002-07-23 メルク・アンド・カンパニー・インコーポレーテッド イヌ成長ホルモン分泌促進物質受容体
WO2000012047A2 (en) * 1998-09-02 2000-03-09 Merck & Co., Inc. Enhancement of return to independent living status with a growth hormone secretagogue
EP1232175B1 (de) * 1999-11-22 2009-07-08 ZymoGenetics, Inc. Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
AU2001259056A1 (en) * 2000-05-17 2001-11-26 Eli Lilly And Company Method for selectively inhibiting ghrelin action
ATE446758T1 (de) 2000-05-31 2009-11-15 Pfizer Prod Inc Verwendung von wachstumshormonsekretagoga zur förderung der beweglichkeit des verdauungstrakts
ATE496940T1 (de) 2002-07-23 2011-02-15 Ipsen Pharma Ghrelin-analoga
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
CA2677399C (en) 2007-02-09 2016-09-13 Tranzyme Pharma, Inc. Macrocyclic ghrelin receptor modulators and methods of using the same
WO2011053821A1 (en) 2009-10-30 2011-05-05 Tranzyme Pharma, Inc. Macrocyclic ghrelin receptor antagonists and inverse agonists and methods of using the same
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5057417A (en) * 1987-06-12 1991-10-15 Genentech, Inc. Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
US5583010A (en) * 1992-06-23 1996-12-10 American Cyanamid Company Nucleic acid molecule encoding the porcine growth hormone receptor

Also Published As

Publication number Publication date
CA2240427C (en) 2007-08-14
EP0876402A4 (de) 2002-08-07
DE69633637T2 (de) 2006-03-09
EP0876402A1 (de) 1998-11-11
DE69633637D1 (de) 2004-11-18
ES2229289T3 (es) 2005-04-16
WO1997021730A1 (en) 1997-06-19
JPH11510706A (ja) 1999-09-21
JP3754084B2 (ja) 2006-03-08
EP0876402B1 (de) 2004-10-13
CA2240427A1 (en) 1997-06-19

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties