ATE279927T1 - Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi - Google Patents

Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi

Info

Publication number
ATE279927T1
ATE279927T1 AT01949437T AT01949437T ATE279927T1 AT E279927 T1 ATE279927 T1 AT E279927T1 AT 01949437 T AT01949437 T AT 01949437T AT 01949437 T AT01949437 T AT 01949437T AT E279927 T1 ATE279927 T1 AT E279927T1
Authority
AT
Austria
Prior art keywords
xanthang
gum
pharmaceutical compositions
compositions containing
containing tobramycin
Prior art date
Application number
AT01949437T
Other languages
English (en)
Inventor
Perdiguer Nuria Carreras
Mas Jose Alberto Vallet
Cabello Gemma Torrella
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of ATE279927T1 publication Critical patent/ATE279927T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT01949437T 2000-07-28 2001-06-26 Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi ATE279927T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22166000P 2000-07-28 2000-07-28
PCT/EP2001/007267 WO2002009724A1 (en) 2000-07-28 2001-06-26 Pharmaceutical compositions containing tobramycin and xanthan gum

Publications (1)

Publication Number Publication Date
ATE279927T1 true ATE279927T1 (de) 2004-11-15

Family

ID=22828757

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01949437T ATE279927T1 (de) 2000-07-28 2001-06-26 Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi

Country Status (18)

Country Link
US (1) US6352978B1 (de)
EP (1) EP1305033B1 (de)
CN (1) CN1218689C (de)
AR (1) AR029965A1 (de)
AT (1) ATE279927T1 (de)
AU (1) AU2001270593A1 (de)
BR (1) BR0112787B1 (de)
CA (1) CA2414737C (de)
CO (1) CO5300418A1 (de)
DE (1) DE60106619T2 (de)
DK (1) DK1305033T3 (de)
ES (1) ES2225573T3 (de)
MX (1) MXPA03000813A (de)
PL (1) PL199321B1 (de)
PT (1) PT1305033E (de)
TW (1) TWI282278B (de)
WO (1) WO2002009724A1 (de)
ZA (1) ZA200300110B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939511B2 (en) * 2004-09-28 2011-05-10 Senju Pharmaceutical Co., Ltd. Ophthalmic composition containing xanthan gum and amino acid
US7795316B1 (en) 2007-12-19 2010-09-14 Alcon Research, Ltd. Topical ophthalmic compositions containing tobramycin and dexamethasone
TWI495469B (zh) 2008-06-09 2015-08-11 Alcon Res Ltd 含有氟喹諾酮抗生素藥物之經改良藥學組成物
EP2585037A1 (de) * 2010-06-23 2013-05-01 Alcon Research, Ltd. Topische ophthalmische suspensionen mit tobramycin und dexamethason
WO2012151474A2 (en) 2011-05-04 2012-11-08 Trustees Of Boston University Proton-motive force stimulation to potentiate aminoglycoside antibiotics against persistent bacteria

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700451A (en) 1970-04-06 1972-10-24 Itek Corp Gelable and gelled compositions
US3944427A (en) 1970-04-06 1976-03-16 Itek Corporation Gelable and gelled compositions
US3784712A (en) 1970-12-23 1974-01-08 Gen Foods Corp Gum gelling system xanthan-tara dessert gel
CA1070629A (en) 1975-11-10 1980-01-29 Allen I. Laskin Process for modifying biopolymers
US4135979A (en) 1976-08-24 1979-01-23 Merck & Co., Inc. Treatment of xanthan gum to improve clarity
US4136178A (en) 1977-01-31 1979-01-23 American Home Products Corp. Locust bean gum therapeutic compositions
US4136177A (en) 1977-01-31 1979-01-23 American Home Products Corp. Xanthan gum therapeutic compositions
US4136173A (en) 1977-01-31 1979-01-23 American Home Products Corp. Mixed xanthan gum and locust beam gum therapeutic compositions
GB8318403D0 (en) 1983-07-07 1983-08-10 Sutherland I W Gel-forming polysaccharides
FR2551087B1 (fr) 1983-08-30 1986-03-21 Rhone Poulenc Spec Chim Procede de traitement d'une solution de polysaccharide et son utilisation
DE3335593A1 (de) 1983-09-30 1985-04-11 Diamalt AG, 8000 München Gelier- und verdickungsmittel auf der basis von cassia-galactomannanen
US4717713A (en) 1983-10-31 1988-01-05 Research Corporation Controlled release liquid pharmaceutical
US4708861A (en) 1984-02-15 1987-11-24 The Liposome Company, Inc. Liposome-gel compositions
FR2588189B1 (fr) 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
US4647470A (en) 1985-11-27 1987-03-03 Merck & Co., Inc. Low-acetyl gellan gum blends
FR2618333B1 (fr) 1987-07-20 1990-07-13 Merck Sharp & Dohme Composition pharmaceutique et/ou cosmetique a usage topique contenant de la gomme rhamsam
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US4814160A (en) 1988-03-01 1989-03-21 Colgate-Palmolive Company Non-bleeding striped dentifrice
US5234957A (en) 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5446070A (en) 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5149694A (en) 1988-03-09 1992-09-22 Alcon Laboratories, Inc. Combination of tobramycin and dexamethasone for topical ophthalmic use
DE3843416A1 (de) 1988-12-23 1990-06-28 Wolff Walsrode Ag Xanthan mit verbesserter loeslichkeit und verfahren zur herstellung
CA2021414C (en) 1989-07-25 2004-09-28 Daniel H. Doherty Genetic control of acetylation and pyruvylation of xanthan gum
US5461081A (en) 1989-09-28 1995-10-24 Alcon Laboratories, Inc. Topical ophthalmic pharmaceutical vehicles
FR2653021A1 (fr) 1989-10-17 1991-04-19 Merck Sharp & Dohme Composition ophtalmique aqueuse liquide a transition de phase liquide-gel.
JP2594486B2 (ja) 1991-01-15 1997-03-26 アルコン ラボラトリーズ インコーポレイテッド 局所的眼薬組成物
CA2064160C (en) * 1991-03-27 1998-08-11 Paul J. T. Missel Use of combinations of gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
US5212162A (en) 1991-03-27 1993-05-18 Alcon Laboratories, Inc. Use of combinations gelling polysaccharides and finely divided drug carrier substrates in topical ophthalmic compositions
AU2672892A (en) 1991-09-17 1993-04-27 Alcon Laboratories, Inc. Compositions containing quinolone antibiotics and sulfonate of polystyrol
US5192802A (en) 1991-09-25 1993-03-09 Mcneil-Ppc, Inc. Bioadhesive pharmaceutical carrier
US5318780A (en) 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
US5473062A (en) 1992-10-29 1995-12-05 Takeda Chemical Industries, Ltd. Process for producing purified xanthan gum
JP3228315B2 (ja) 1993-04-23 2001-11-12 信越化学工業株式会社 キサンタンガムの汚染生菌数を減少させる方法
JPH09510961A (ja) 1994-01-14 1997-11-04 ジュニア シャヒニアン,リー 持続性および長期間の角膜鎮痛の方法
US5422116A (en) 1994-02-18 1995-06-06 Ciba-Geigy Corporation Liquid ophthalmic sustained release delivery system
JP4259610B2 (ja) 1994-04-08 2009-04-30 キューエルティー・ユーエスエイ・インコーポレーテッド 液体デリバリー組成物
US5523301A (en) 1994-08-05 1996-06-04 Merck & Co., Inc. Optic nerve health
DK0725628T3 (da) 1994-08-30 2001-12-27 Alcon Lab Inc Termisk geldannende lægemiddelindgivelsesvehikler indeholdende celluloseethere
US5972326A (en) 1995-04-18 1999-10-26 Galin; Miles A. Controlled release of pharmaceuticals in the anterior chamber of the eye
FR2742336B1 (fr) 1995-12-19 1998-03-06 Chauvin Lab Sa Collyre destine notamment au traitement de l'oeil sec
SE9603480L (sv) 1996-09-23 1998-03-24 Johan Carlfors Beredningsform för svårlösliga läkemedel
FR2754712B1 (fr) 1996-10-17 1999-09-03 Merck Sharp Dohme Chibret Lab Compositions ophtalmiques
US5888493A (en) 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
WO1998053809A1 (en) 1997-05-30 1998-12-03 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
KR20010013377A (ko) * 1997-06-04 2001-02-26 데이비드 엠 모이어 마일드한 잔류성 항균 조성물
JP2002506461A (ja) 1997-06-26 2002-02-26 メルク エンド カンパニー インコーポレーテッド 網膜及び視神経の健康の最適化方法
US6174524B1 (en) * 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
DE69909768T2 (de) * 1998-04-07 2004-06-17 Alcon Manufacturing Ltd., Fort Worth Xanthangummi enthaltende gelbildende ophthalmische zusammensetzungen
US6297337B1 (en) * 1999-05-19 2001-10-02 Pmd Holdings Corp. Bioadhesive polymer compositions

Also Published As

Publication number Publication date
US20020035088A1 (en) 2002-03-21
WO2002009724A1 (en) 2002-02-07
MXPA03000813A (es) 2005-08-16
EP1305033A1 (de) 2003-05-02
CA2414737C (en) 2009-01-06
BR0112787A (pt) 2003-09-09
CA2414737A1 (en) 2002-02-07
TWI282278B (en) 2007-06-11
AR029965A1 (es) 2003-07-23
ZA200300110B (en) 2004-01-21
AU2001270593A1 (en) 2002-02-13
BR0112787B1 (pt) 2013-03-05
DE60106619T2 (de) 2005-03-17
DK1305033T3 (da) 2005-01-31
PL365154A1 (en) 2004-12-27
PT1305033E (pt) 2005-01-31
CN1218689C (zh) 2005-09-14
CO5300418A1 (es) 2003-07-31
US6352978B1 (en) 2002-03-05
DE60106619D1 (de) 2004-11-25
ES2225573T3 (es) 2005-03-16
EP1305033B1 (de) 2004-10-20
PL199321B1 (pl) 2008-09-30
CN1444482A (zh) 2003-09-24

Similar Documents

Publication Publication Date Title
DE60142197D1 (de) Pharmazeutische Zusammensetzung
AT7729U3 (de) Pharmazeutische zusammensetzungen enthaltend amlodipinmaleat
DE69924999D1 (de) Lipasehemmer enthaltende pharmazeutische zusammensetzungen
EP1458362A4 (de) Pharmazeutische zusammensetzungen in teilchenform
EE200300145A (et) Asa- ja polüasanaftalenüülkarboksamiidid ja farmatseutiline kompositsioon
HUP0302550A3 (en) Glucopyranosyloxypyrazole derivatives and use thereof in medicines and pharmaceutical compositions containing them
ATE331529T1 (de) Antigen enthaltende pharmazeutische zusammensetzung
ATE404180T1 (de) Geschmacksmaskierte pharmazeutische partikel
IL152718A0 (en) Piperidine derivatives and pharmaceutical compositions containing the same
ATE263558T1 (de) Lipasehemmer und chitosan enthaltende pharmazeutische zusammensetzungen
DE60003445D1 (de) Pharmazeutische zusammensetzungen ein fluorchinolonantibiotikum und xanthangummi enthaltend
DE69900561D1 (de) Pharmazeutische Zusammensetzungen enthaltend Mupirocin
DE60322454D1 (de) Pharmazeutische Zusammensetzungen zur oralen und topischen Verabreichung
ATE383868T1 (de) Pharmazeutische formulierung enthaltend megalatran und dessen pro-pharmaka
HUP0301713A3 (en) Pharmaceutical compositions containing propenone derivatives and their use
ATE366128T1 (de) Pharmazeutische zusammensetzung
ATE350016T1 (de) Bicalutamid enthaltende pharmazeutische zusammensetzung
DE10084344T1 (de) Cyclosporin enthaltende pharmazeutische Zusammensetzung
HUP0303204A3 (en) 1-methylcarbapenem derivatives and pharmaceutical compositions containing them
ATE228839T1 (de) Tizoxanide und nitazoxanide enthaltende pharmazeutische zusammensetzungen
ATE290543T1 (de) Pharmazeutische zusammensetzungen mit oligosacchariden und deren herstellung
ATE279927T1 (de) Pharmazeutische zusammensetzungen enthaltend tobramycin und xanthangummi
HUP0203383A3 (en) Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof
EP1124557A4 (de) Pharmazeutische zusammensetzung
AU4834101A (en) N-deacetylthiocolchicine derivatives and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1305033

Country of ref document: EP