ATE280246T1 - Polymorphismuserkennung mit hilfe cluster-analyse - Google Patents

Polymorphismuserkennung mit hilfe cluster-analyse

Info

Publication number
ATE280246T1
ATE280246T1 AT98944444T AT98944444T ATE280246T1 AT E280246 T1 ATE280246 T1 AT E280246T1 AT 98944444 T AT98944444 T AT 98944444T AT 98944444 T AT98944444 T AT 98944444T AT E280246 T1 ATE280246 T1 AT E280246T1
Authority
AT
Austria
Prior art keywords
sample polymers
cluster analysis
polymorphism detection
differences
polymers
Prior art date
Application number
AT98944444T
Other languages
English (en)
Inventor
Anthony Berno
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Application granted granted Critical
Publication of ATE280246T1 publication Critical patent/ATE280246T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Holo Graphy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Control By Computers (AREA)
  • Image Analysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98944444T 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse ATE280246T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5593997P 1997-08-15 1997-08-15
PCT/US1998/016971 WO1999009218A1 (en) 1997-08-15 1998-08-14 Polymorphism detection utilizing clustering analysis

Publications (1)

Publication Number Publication Date
ATE280246T1 true ATE280246T1 (de) 2004-11-15

Family

ID=22001120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98944444T ATE280246T1 (de) 1997-08-15 1998-08-14 Polymorphismuserkennung mit hilfe cluster-analyse

Country Status (8)

Country Link
US (3) US6223127B1 (de)
EP (1) EP1019536B1 (de)
JP (1) JP2001514907A (de)
AT (1) ATE280246T1 (de)
AU (1) AU9198298A (de)
CA (1) CA2299625A1 (de)
DE (1) DE69827154T2 (de)
WO (1) WO1999009218A1 (de)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US6223127B1 (en) * 1997-08-15 2001-04-24 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis
US6979728B2 (en) 1998-05-04 2005-12-27 Baylor College Of Medicine Articles of manufacture and methods for array based analysis of biological molecules
US6699659B2 (en) 1998-06-01 2004-03-02 Affymetrix, Inc. Products and methods for analyzing nucleic acids including identification of substitutions, insertions and deletions
US6245511B1 (en) * 1999-02-22 2001-06-12 Vialogy Corp Method and apparatus for exponentially convergent therapy effectiveness monitoring using DNA microarray based viral load measurements
US6142681A (en) 1999-02-22 2000-11-07 Vialogy Corporation Method and apparatus for interpreting hybridized bioelectronic DNA microarray patterns using self-scaling convergent reverberant dynamics
US20040111219A1 (en) * 1999-02-22 2004-06-10 Sandeep Gulati Active interferometric signal analysis in software
US6136541A (en) 1999-02-22 2000-10-24 Vialogy Corporation Method and apparatus for analyzing hybridized biochip patterns using resonance interactions employing quantum expressor functions
US7179638B2 (en) 1999-07-30 2007-02-20 Large Scale Biology Corporation Microarrays and their manufacture by slicing
US6713309B1 (en) 1999-07-30 2004-03-30 Large Scale Proteomics Corporation Microarrays and their manufacture
US20020052692A1 (en) * 1999-09-15 2002-05-02 Eoin D. Fahy Computer systems and methods for hierarchical cluster analysis of large sets of biological data including highly dense gene array data
US6934636B1 (en) 1999-10-22 2005-08-23 Genset, S.A. Methods of genetic cluster analysis and uses thereof
JP3563315B2 (ja) 1999-12-14 2004-09-08 日立ソフトウエアエンジニアリング株式会社 樹状図表示方法及び樹状図表示システム
US20020067358A1 (en) * 2000-01-21 2002-06-06 Georg Casari Data analysis software
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
US20040101878A1 (en) * 2000-12-22 2004-05-27 Jones Michael H. High-throughput screening system by microarrays
US20020183936A1 (en) * 2001-01-24 2002-12-05 Affymetrix, Inc. Method, system, and computer software for providing a genomic web portal
WO2003005628A2 (en) * 2001-07-06 2003-01-16 Lipomics Technologies, Inc. Generating, viewing, interpreting, and utilizing a quantitative database of metabolites
US6799122B2 (en) * 2001-08-31 2004-09-28 Conagra Grocery Products Company Method for identifying polymorphic markers in a population
ATE443264T1 (de) * 2001-09-24 2009-10-15 Lipomics Technologies Inc Verfahren zur verwendung von quantitativen lipidmetabolondaten
CA2463725A1 (en) 2001-10-12 2003-11-06 Spectral Genomics, Inc. Compilations of nucleic acids and arrays and methods of using them
US7439346B2 (en) 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
AU2002357368A1 (en) * 2001-12-19 2003-07-09 Affymetrix, Inc. Array plates and method for constructing array plates
US7272506B2 (en) * 2002-03-01 2007-09-18 Applera Corporation Computer algorithm for automatic allele determination from fluorometer genotyping device
WO2003093296A2 (en) 2002-05-03 2003-11-13 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
DE60323625D1 (de) * 2002-05-03 2008-10-30 Vialogy Llc Verfahren zur charakterisierung der ausgangssignale eines microarrays
US20050089909A1 (en) * 2002-05-31 2005-04-28 Mcgill University PTHrP-based prediction and diagnosis of bone disease
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
EP2112229A3 (de) 2002-11-25 2009-12-02 Sequenom, Inc. Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
EP2327795B1 (de) 2003-06-10 2017-08-09 The Trustees Of Boston University Nachweismethoden für Lungenerkrankungen
US7259258B2 (en) * 2003-12-17 2007-08-21 Illumina, Inc. Methods of attaching biological compounds to solid supports using triazine
CA2497324A1 (en) 2004-02-17 2005-08-17 Affymetrix, Inc. Methods for fragmenting and labelling dna
US7035740B2 (en) * 2004-03-24 2006-04-25 Illumina, Inc. Artificial intelligence and global normalization methods for genotyping
US20050282174A1 (en) * 2004-06-19 2005-12-22 Webb Peter G Methods and systems for selecting nucleic acid probes for microarrays
US20080199480A1 (en) * 2004-07-22 2008-08-21 Sequenom, Inc. Methods for Identifying Risk of Type II Diabetes and Treatments Thereof
EP1792263A2 (de) * 2004-09-02 2007-06-06 Vialogy Corporation Erkennung von interessensereignissen unter verwendung von quantenresonanzinterferometrie
US20060073506A1 (en) 2004-09-17 2006-04-06 Affymetrix, Inc. Methods for identifying biological samples
US20060073511A1 (en) 2004-10-05 2006-04-06 Affymetrix, Inc. Methods for amplifying and analyzing nucleic acids
US7682782B2 (en) 2004-10-29 2010-03-23 Affymetrix, Inc. System, method, and product for multiple wavelength detection using single source excitation
CA2524964A1 (en) 2004-10-29 2006-04-29 Affymetrix, Inc. Automated method of manufacturing polymer arrays
EP3211093A1 (de) 2005-04-14 2017-08-30 The Trustees of Boston University Diagnose für lungenerkrankungen mittels klassenvorhersage
US20070173139A1 (en) * 2006-01-24 2007-07-26 Charles Gierke Fishing assembly
WO2007103541A2 (en) 2006-03-09 2007-09-13 The Trustees Of Boston University Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells
EP3617321B1 (de) 2006-05-31 2024-10-23 Sequenom, Inc. Kit zur nukleinsäureextraktion und -verstärkung aus einer probe
CA2654165A1 (en) 2006-06-05 2007-12-13 Cancer Care Ontario Assessment of risk for colorectal cancer
AU2007284651B2 (en) 2006-08-09 2014-03-20 Institute For Systems Biology Organ-specific proteins and methods of their use
US9845494B2 (en) 2006-10-18 2017-12-19 Affymetrix, Inc. Enzymatic methods for genotyping on arrays
AU2007325931A1 (en) 2006-11-02 2008-06-05 Yale University Assessment of oocyte competence
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US8165821B2 (en) * 2007-02-05 2012-04-24 Applied Biosystems, Llc System and methods for indel identification using short read sequencing
AU2008213634B2 (en) * 2007-02-08 2013-09-05 Sequenom, Inc. Nucleic acid-based tests for RhD typing, gender determination and nucleic acid quantification
EP2243834A1 (de) 2007-03-05 2010-10-27 Cancer Care Ontario Abschätzung des Kolorektalkarzinomrisikos
US8652780B2 (en) 2007-03-26 2014-02-18 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8200440B2 (en) 2007-05-18 2012-06-12 Affymetrix, Inc. System, method, and computer software product for genotype determination using probe array data
WO2009032781A2 (en) 2007-08-29 2009-03-12 Sequenom, Inc. Methods and compositions for universal size-specific polymerase chain reaction
EP2271772B1 (de) 2008-03-11 2014-07-16 Sequenom, Inc. Tests auf nukleinsäurebasis zur pränatalen geschlechtsbestimmung
AU2009224170B2 (en) * 2008-03-11 2012-03-29 National Cancer Center Method for measuring chromosome, gene or specific nucleotide sequence copy numbers using SNP array
WO2009120808A2 (en) 2008-03-26 2009-10-01 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
CA2779958A1 (en) 2008-11-06 2010-05-14 University Of Miami Role of soluble upar in the pathogenesis of proteinuric kidney disease
WO2010080933A1 (en) 2009-01-07 2010-07-15 Myriad Genetics, Inc Cancer biomarkers
EP3722810A3 (de) 2009-02-11 2021-01-13 Caris MPI, Inc. Molekulare profilierung von tumoren
CA2755615A1 (en) * 2009-03-18 2010-09-23 Sequenom, Inc. Use of thermostable endonucleases for generating reporter molecules
EP3514244B1 (de) 2009-04-03 2021-07-07 Sequenom, Inc. Verfahren für die herstellung von nukleinsäuren
EP2494077A4 (de) 2009-10-27 2013-08-21 Caris Mpi Inc Molekulare profilierung für personalisierte medizin
US20110201008A1 (en) * 2009-12-01 2011-08-18 University Of Miami Assays, methods and kits for measuring response to therapy and predicting clinical outcome in patients with b-cell lymphoma
US8501122B2 (en) 2009-12-08 2013-08-06 Affymetrix, Inc. Manufacturing and processing polymer arrays
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
ES2577017T3 (es) 2009-12-22 2016-07-12 Sequenom, Inc. Procedimientos y kits para identificar la aneuploidia
US9798855B2 (en) 2010-01-07 2017-10-24 Affymetrix, Inc. Differential filtering of genetic data
US9216189B2 (en) 2010-01-25 2015-12-22 Icahn School Of Medicine At Mount Sinai Antibodies which bind type I cannabinoid receptor/angiotensis II receptor heteromers
CA2797093C (en) 2010-04-26 2019-10-29 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
EP2563381B1 (de) 2010-04-27 2017-08-09 aTyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von isoleucyl-trna-synthetasen
CN103097524B (zh) 2010-04-28 2016-08-03 Atyr医药公司 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
EP2563383B1 (de) 2010-04-29 2017-03-01 Atyr Pharma, Inc. Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von valyl-trna-synthetasen
CA2797374C (en) 2010-04-29 2021-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases
WO2011137368A2 (en) 2010-04-30 2011-11-03 Life Technologies Corporation Systems and methods for analyzing nucleic acid sequences
AU2011248227B2 (en) 2010-05-03 2016-12-01 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases
CN103096925A (zh) 2010-05-03 2013-05-08 Atyr医药公司 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
ES2668207T3 (es) 2010-05-03 2018-05-17 Atyr Pharma, Inc. Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de metionil-ARNt sintetasas
JP6008844B2 (ja) 2010-05-04 2016-10-19 エータイアー ファーマ， インコーポレイテッド ｐ３８ＭＵＬＴＩ−ｔＲＮＡ合成酵素複合体のタンパク質フラグメントに関連した治療用、診断用および抗体組成物の革新的発見
EP2568996B1 (de) 2010-05-14 2017-10-04 aTyr Pharma, Inc. Therapeutische, diagnostische und antikörperhaltige zusammensetzungen im zusammenhang mit proteinfragmenten von phenylalanyl-beta-trna-synthetasen
CN103096913B (zh) 2010-05-27 2017-07-18 Atyr 医药公司 与谷氨酰胺酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
CA2800281C (en) 2010-06-01 2021-01-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
EP3812469A1 (de) 2010-07-07 2021-04-28 Myriad Genetics, Inc. Gensignaturen für krebsprognosen
AU2011289831C1 (en) 2010-07-12 2017-06-15 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
CN103108650A (zh) 2010-08-25 2013-05-15 Atyr医药公司 与酪氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现
AU2012249531B2 (en) 2011-04-29 2017-06-29 Sequenom, Inc. Quantification of a minority nucleic acid species
AU2012367247B2 (en) 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
EP2814514B1 (de) 2012-02-16 2017-09-13 Atyr Pharma, Inc. Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen
EP2820174B1 (de) 2012-02-27 2019-12-25 The University of North Carolina at Chapel Hill Verfahren und verwendung für molekulare tags
CA2865575C (en) 2012-02-27 2024-01-16 Cellular Research, Inc. Compositions and kits for molecular counting
EP2820129A1 (de) 2012-03-02 2015-01-07 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
WO2013184905A1 (en) 2012-06-06 2013-12-12 Myriad Genetics, Inc. Hereditary cancer genes
US20140093873A1 (en) 2012-07-13 2014-04-03 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
CA2891653A1 (en) 2012-11-16 2014-05-22 Myriad Genetics, Inc. Gene signatures for cancer prognosis
CN104937111B (zh) 2012-11-27 2018-05-11 智利天主教教皇大学 用于诊断甲状腺肿瘤的组合物和方法
US9896728B2 (en) 2013-01-29 2018-02-20 Arcticrx Ltd. Method for determining a therapeutic approach for the treatment of age-related macular degeneration (AMD)
US11060145B2 (en) 2013-03-13 2021-07-13 Sequenom, Inc. Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
US11021752B2 (en) 2013-03-15 2021-06-01 Myriad Genetics, Inc. Genes and gene signatures for diagnosis and treatment of melanoma
US10535420B2 (en) 2013-03-15 2020-01-14 Affymetrix, Inc. Systems and methods for probe design to detect the presence of simple and complex indels
US20140274749A1 (en) 2013-03-15 2014-09-18 Affymetrix, Inc. Systems and Methods for SNP Characterization and Identifying off Target Variants
SG11201601044XA (en) 2013-08-12 2016-03-30 Genentech Inc Compositions and method for treating complement-associated conditions
EP3102230B1 (de) 2014-02-08 2021-04-28 F. Hoffmann-La Roche AG Verfahren zur behandlung von morbus alzheimer
EP3736344A1 (de) 2014-03-13 2020-11-11 Sequenom, Inc. Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
EP3748011B1 (de) 2014-04-22 2024-11-13 Envirologix Inc. Zusammensetzungen und verfahren zur verbesserung und/oder vorhersage der dna-amplifikation
CA2947624A1 (en) 2014-05-13 2015-11-19 Myriad Genetics, Inc. Gene signatures for cancer prognosis
EP3164508B1 (de) 2014-07-02 2023-06-07 Myriad myPath, LLC Gene und gensignaturen zur diagnose und behandlung von melanomen
CN107208137A (zh) 2014-10-20 2017-09-26 龙公司 检测rna病毒的组合物和方法
RU2755495C2 (ru) 2015-01-30 2021-09-16 Инвайролоджикс Инк. Молекула субстрата
CN108136051A (zh) 2015-08-04 2018-06-08 Cd诊断股份有限公司 检测不良局部组织反应(altr)坏死的方法
JP6858783B2 (ja) 2015-10-18 2021-04-14 アフィメトリックス インコーポレイテッド 一塩基多型及びインデルの複対立遺伝子遺伝子型決定
EP3377650A1 (de) 2015-11-19 2018-09-26 Susanne Wagner Signaturen zur vorhersage der krebsimmuntherapiereaktion
CA3010240A1 (en) 2016-01-06 2017-07-13 Alexander Gutin Genes and gene signatures for diagnosis and treatment of melanoma
WO2017193062A1 (en) 2016-05-06 2017-11-09 Myriad Genetics, Inc. Gene signatures for renal cancer prognosis
US12577622B2 (en) 2017-06-02 2026-03-17 Myriad Genetics, Inc. Detecting cancer risk
WO2019005763A1 (en) 2017-06-26 2019-01-03 Phase Genomics Inc. METHOD FOR REGROUPING DNA SEQUENCES
US20190211098A1 (en) 2017-12-22 2019-07-11 Genentech, Inc. Use of pilra binding agents for treatment of a disease
WO2019232067A1 (en) 2018-05-29 2019-12-05 Centrillion Technologies, Inc. Increasing efficiency of photochemical reactions on substrates
WO2019246160A2 (en) 2018-06-18 2019-12-26 Igenomix, S.L. Methods, compositions, and kits for assessing endometrial transformation
CA3115922A1 (en) 2018-10-09 2020-04-16 Genecentric Therapeutics, Inc. Detecting cancer cell of origin
EP3888021B1 (de) 2018-11-30 2024-02-21 Caris MPI, Inc. Molekulare profilierung der nächsten generation
EP3956476A1 (de) 2019-04-17 2022-02-23 Igenomix S.L. Verbesserte verfahren zur frühdiagnose von uterinen leiomyomen und leiomyosarkomen
CA3163319A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5837832A (en) * 1993-06-25 1998-11-17 Affymetrix, Inc. Arrays of nucleic acid probes on biological chips
WO1995011995A1 (en) * 1993-10-26 1995-05-04 Affymax Technologies N.V. Arrays of nucleic acid probes on biological chips
WO1997027317A1 (en) * 1996-01-23 1997-07-31 Affymetrix, Inc. Nucleic acid analysis techniques
US5830645A (en) * 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
GB9521089D0 (en) * 1995-10-14 1995-12-20 Aromascan Plc Cluster analysis
AU2189397A (en) * 1996-02-08 1997-08-28 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6223127B1 (en) * 1997-08-15 2001-04-24 Affymetrix, Inc. Polymorphism detection utilizing clustering analysis

Also Published As

Publication number Publication date
WO1999009218A1 (en) 1999-02-25
CA2299625A1 (en) 1999-02-25
DE69827154D1 (de) 2004-11-25
JP2001514907A (ja) 2001-09-18
AU9198298A (en) 1999-03-08
US20040024537A1 (en) 2004-02-05
US6223127B1 (en) 2001-04-24
EP1019536A1 (de) 2000-07-19
EP1019536B1 (de) 2004-10-20
US20010041965A1 (en) 2001-11-15
EP1019536A4 (de) 2002-08-14
DE69827154T2 (de) 2006-03-09
US6584410B2 (en) 2003-06-24

Similar Documents

Publication Publication Date Title
ATE280246T1 (de) Polymorphismuserkennung mit hilfe cluster-analyse
WO2001009381A3 (en) Methods of nucleic acid analysis by detecting molecular binding events
WO2001059161A3 (en) Analyte assays employing universal arrays
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
BR9908567A (pt) Processos de detecção de ácido nucléico zimogênico e moléculas relacionadas e kits
EP1288313A3 (de) System und Verfahren zum Testen von Nukleinsäuremolekülen
WO2005010494A3 (en) Multiplexed analyte detection
FI106871B (fi) Menetelmä nukleiinihapon tietyssä asemassa olevan nukleotidiemäksen tunnistamiseksi
AU2001282920A1 (en) Methods for detecting and assaying nucleic acid sequences
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
WO2002054067A3 (en) Detection of analytes
WO2003102546A3 (en) Method and apparatus for detecting substances of interest
ES2196811T3 (es) Modelo de seguridad para aplicaciones de television interactiva.
DE60023539D1 (de) Immunologischer nachweis von rna:dna hybriden auf mikroarrays
CA2217074A1 (en) Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis
ATE334743T1 (de) Verwendung von mit polymer beschichtetem sorptionsmittelkomposit zur trennung, reinigung, entsalzung und konzentrierung von biopolymeren
GB2233450B (en) Detecting or quantifing multiple analytes with luminescent reagents
BR0016105A (pt) Oligonucleotìdeo ou conjunto de oligonucleotìdeo úteis na detecção da presença ou ausência de ácidos nucléicos alvos numa amostra, sistema de oligonucleotìdeo útil para detectar a presença ou ausência de uma sequência de ácidos nucléicos alvos numa amostra, método para detectar a presença ou ausência de uma sequência de ácidos nucléicos alvos numa amostra
ATE264923T1 (de) Verfahren und system zur erkennung von oligonukleotiden in einer probe
EP0707075A3 (de) Spezies-spezifischer Nachweis von Mycobacterium Kansasii
JP2005521411A5 (de)
EP1360329B8 (de) Biochemische methode und apparat zur detektion genetischer charakteristika
AUPR221400A0 (en) Diagnostic assay
ATE513058T1 (de) Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen
WO2003054149A3 (en) Targeted genetic risk-stratification using microarrays

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties