ATE280759T1 - Diaminderivate und pharmazeutische zusammensetzungen die diese enthalten - Google Patents

Diaminderivate und pharmazeutische zusammensetzungen die diese enthalten

Info

Publication number
ATE280759T1
ATE280759T1 AT98929866T AT98929866T ATE280759T1 AT E280759 T1 ATE280759 T1 AT E280759T1 AT 98929866 T AT98929866 T AT 98929866T AT 98929866 T AT98929866 T AT 98929866T AT E280759 T1 ATE280759 T1 AT E280759T1
Authority
AT
Austria
Prior art keywords
single bond
group
lower alkyl
value
alkyl group
Prior art date
Application number
AT98929866T
Other languages
English (en)
Inventor
Henk Timmerman
Mingqiang Zang
Kazuhiro Onogi
Masahiro Tamura
Tsutomu Tohma
Yasushi Wada
Original Assignee
Kowa Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co filed Critical Kowa Co
Application granted granted Critical
Publication of ATE280759T1 publication Critical patent/ATE280759T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
AT98929866T 1997-07-07 1998-07-07 Diaminderivate und pharmazeutische zusammensetzungen die diese enthalten ATE280759T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18119697 1997-07-07
PCT/JP1998/003054 WO1999002520A1 (en) 1997-07-07 1998-07-07 Diamine derivatives and pharmaceutical containing the same

Publications (1)

Publication Number Publication Date
ATE280759T1 true ATE280759T1 (de) 2004-11-15

Family

ID=16096534

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98929866T ATE280759T1 (de) 1997-07-07 1998-07-07 Diaminderivate und pharmazeutische zusammensetzungen die diese enthalten

Country Status (10)

Country Link
US (1) US6127360A (de)
EP (1) EP0957100B1 (de)
JP (1) JP3588126B2 (de)
KR (1) KR100538152B1 (de)
AT (1) ATE280759T1 (de)
DE (1) DE69827233T2 (de)
DK (1) DK0957100T3 (de)
ES (1) ES2231992T3 (de)
PT (1) PT957100E (de)
WO (1) WO1999002520A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2176877T3 (es) * 1997-09-26 2002-12-01 Kowa Co Derivados de tetrazol como antagonistas de ltd4 y h1.
DE10035928A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10102053A1 (de) * 2001-01-17 2002-07-18 Merck Patent Gmbh Piperazinylcarbonylchinoline und -isochinoline
ATE440825T1 (de) * 2003-06-06 2009-09-15 Vertex Pharma Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
TW200613278A (en) * 2004-09-03 2006-05-01 Kowa Co 7-substituted-carbostyril derivative and preparation method thereof
WO2006025479A1 (ja) * 2004-09-03 2006-03-09 Kowa Co., Ltd. Ｎ－（１－メチルベンゾイミダゾール－２－イル）メチル－ｎ’－２－［（カルボスチリル－７－イル）オキシ］エチルホモピペラジンの製造方法
TW201139432A (en) * 2010-03-18 2011-11-16 Kowa Co Monomaleate of benzothiazine compound
WO2011115150A1 (ja) * 2010-03-18 2011-09-22 興和株式会社 ベンゾチアジン化合物の製造方法
US9302992B2 (en) 2013-04-02 2016-04-05 Annji Pharmaceutical Co., Ltd. Multifunctional quinoline derivatives as anti-neurodegenerative agents
BR112015024472A2 (pt) * 2013-04-02 2017-07-18 Annji Pharm Co Ltd derivados de quinolina multifuncionais como agentes anti-neurodegenerativos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07149646A (ja) * 1993-11-29 1995-06-13 Asahi Chem Ind Co Ltd ケミカルメディエーター遊離抑制剤
JP3834089B2 (ja) * 1995-06-14 2006-10-18 株式会社日清製粉グループ本社 ベンズイミダゾール誘導体を含有するぜん息治療剤
JPH09227561A (ja) * 1996-02-21 1997-09-02 Tanabe Seiyaku Co Ltd キサンチン誘導体
ES2176877T3 (es) * 1997-09-26 2002-12-01 Kowa Co Derivados de tetrazol como antagonistas de ltd4 y h1.

Also Published As

Publication number Publication date
US6127360A (en) 2000-10-03
PT957100E (pt) 2005-02-28
EP0957100A4 (de) 2004-04-14
WO1999002520A1 (en) 1999-01-21
JP3588126B2 (ja) 2004-11-10
EP0957100A1 (de) 1999-11-17
KR20000068436A (ko) 2000-11-25
DK0957100T3 (da) 2005-01-31
EP0957100B1 (de) 2004-10-27
DE69827233D1 (de) 2004-12-02
KR100538152B1 (ko) 2005-12-21
DE69827233T2 (de) 2005-03-24
ES2231992T3 (es) 2005-05-16

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