ATE281528T1 - Rekombinante ribonuklease proteine - Google Patents

Rekombinante ribonuklease proteine

Info

Publication number
ATE281528T1
ATE281528T1 AT97906675T AT97906675T ATE281528T1 AT E281528 T1 ATE281528 T1 AT E281528T1 AT 97906675 T AT97906675 T AT 97906675T AT 97906675 T AT97906675 T AT 97906675T AT E281528 T1 ATE281528 T1 AT E281528T1
Authority
AT
Austria
Prior art keywords
recombinant ribonuclease
ribonuclease proteins
proteins
recombinant
ribonucleases
Prior art date
Application number
AT97906675T
Other languages
English (en)
Inventor
Susanna M Rybak
Dianne L Newton
Lluis Boque
Alexander Wlodawer
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Application granted granted Critical
Publication of ATE281528T1 publication Critical patent/ATE281528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/463—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from amphibians
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT97906675T 1996-02-21 1997-02-19 Rekombinante ribonuklease proteine ATE281528T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1180096P 1996-02-21 1996-02-21
PCT/US1997/002588 WO1997031116A2 (en) 1996-02-21 1997-02-19 Recombinant ribonuclease proteins

Publications (1)

Publication Number Publication Date
ATE281528T1 true ATE281528T1 (de) 2004-11-15

Family

ID=21752018

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97906675T ATE281528T1 (de) 1996-02-21 1997-02-19 Rekombinante ribonuklease proteine

Country Status (10)

Country Link
EP (1) EP0896625B1 (de)
JP (1) JP3469247B2 (de)
CN (1) CN1229498C (de)
AT (1) ATE281528T1 (de)
AU (1) AU726379B2 (de)
DE (1) DE69731463T2 (de)
ES (1) ES2232860T3 (de)
IL (2) IL125771A0 (de)
NZ (1) NZ331298A (de)
WO (1) WO1997031116A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6395276B1 (en) * 1997-05-02 2002-05-28 Immunomedics, Inc. Immunotoxins directed against malignant cells
US6555651B2 (en) * 1997-10-09 2003-04-29 The Trustees Of Columbia University In The City Of New York Ligand binding site of rage and uses thereof
EP1062348B1 (de) * 1998-03-11 2005-06-15 Immunomedics, Inc. Rekombinante onconase und fusionsproteine davon
US6869604B1 (en) 1998-03-27 2005-03-22 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Recombinant anti-tumor RNAse
AU755147B2 (en) * 1998-03-27 2002-12-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Recombinant anti-tumor RNASE
EP1277838A1 (de) * 1998-03-27 2003-01-22 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Rekombinante anti-tumor RNAse
US6239257B1 (en) * 1998-12-30 2001-05-29 Alfacell Corporation Family of proteins belonging to the pancreatic ribonuclease a superfamily
US6175003B1 (en) * 1999-09-10 2001-01-16 Alfacell Corporation Nucleic acids encoding ribonucleases and methods of making them
PT2295070E (pt) 2000-04-12 2015-12-07 Life Sciences Res Partners Vzw Utilização de vegf e homólogos para tratar distúrbios do neurónio
CN101228273B (zh) * 2005-07-26 2012-04-25 宝生物工程株式会社 新的核糖核酸内切酶
WO2007041361A1 (en) * 2005-09-30 2007-04-12 The Government Of The United States, As Represented By The Secretary Of Health And Human Services, National Institutes Of Health, Office Of Technology Transfer Modified recombinant anti-tumor rnase
CN101450214B (zh) * 2007-12-06 2011-10-26 上海南方模式生物科技发展有限公司 转铁蛋白-蛙卵核糖核酸酶偶联物及其制法和用途
CN101613410B (zh) * 2008-06-25 2016-01-20 上海南方模式生物科技发展有限公司 核糖核酸酶与毒蛋白膜转位结构域融合蛋白及其制备方法和用途
US9919034B2 (en) 2014-03-28 2018-03-20 Tamir Biotechnology, Inc. Methods of treating and prophylactically protecting mammalian patients infected by viruses classified in Baltimore group V
US10835598B2 (en) 2014-08-18 2020-11-17 Orgenesis Inc. Prophylactic protection against viral infections, particularly HIV
CN107920990A (zh) 2015-06-15 2018-04-17 塔米尔生物技术公司 用于治疗眼睛的病毒性感染的药物
CN113302289A (zh) * 2018-11-14 2021-08-24 Dna斯克瑞普特公司 末端脱氧核苷酸转移酶变体及其用途
WO2024207543A1 (zh) * 2023-04-07 2024-10-10 成都诺恩基因科技有限公司 增加共转染mRNA的蛋白表达水平和表达时长的重组基因及其应用

Also Published As

Publication number Publication date
EP0896625A2 (de) 1999-02-17
AU2130697A (en) 1997-09-10
WO1997031116A3 (en) 1997-09-25
AU726379B2 (en) 2000-11-02
DE69731463D1 (de) 2004-12-09
IL125771A0 (en) 1999-04-11
CN1212016A (zh) 1999-03-24
ES2232860T3 (es) 2005-06-01
EP0896625B1 (de) 2004-11-03
CN1229498C (zh) 2005-11-30
NZ331298A (en) 2000-03-27
DE69731463T2 (de) 2005-10-27
JP2000505300A (ja) 2000-05-09
JP3469247B2 (ja) 2003-11-25
WO1997031116A2 (en) 1997-08-28
IL125771A (en) 2006-08-20

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