ATE283359T1 - Methode zum durchforsten von banken mittels chimären bindungspetiden - Google Patents

Methode zum durchforsten von banken mittels chimären bindungspetiden

Info

Publication number
ATE283359T1
ATE283359T1 AT98940455T AT98940455T ATE283359T1 AT E283359 T1 ATE283359 T1 AT E283359T1 AT 98940455 T AT98940455 T AT 98940455T AT 98940455 T AT98940455 T AT 98940455T AT E283359 T1 ATE283359 T1 AT E283359T1
Authority
AT
Austria
Prior art keywords
dna
fusion protein
carrier package
peptide
protein
Prior art date
Application number
AT98940455T
Other languages
English (en)
Inventor
Duncan Mcgregor
Original Assignee
Rowett Res Services Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rowett Res Services Ltd filed Critical Rowett Res Services Ltd
Application granted granted Critical
Publication of ATE283359T1 publication Critical patent/ATE283359T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98940455T 1997-09-02 1998-09-02 Methode zum durchforsten von banken mittels chimären bindungspetiden ATE283359T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9718455.0A GB9718455D0 (en) 1997-09-02 1997-09-02 Chimeric binding peptide library screening method
PCT/GB1998/002630 WO1999011785A1 (en) 1997-09-02 1998-09-02 Chimeric binding peptide library screening method

Publications (1)

Publication Number Publication Date
ATE283359T1 true ATE283359T1 (de) 2004-12-15

Family

ID=10818309

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940455T ATE283359T1 (de) 1997-09-02 1998-09-02 Methode zum durchforsten von banken mittels chimären bindungspetiden

Country Status (9)

Country Link
US (2) US7312074B1 (de)
EP (1) EP1009827B1 (de)
JP (1) JP4221148B2 (de)
AT (1) ATE283359T1 (de)
AU (1) AU741002B2 (de)
CA (1) CA2301826C (de)
DE (1) DE69827810T2 (de)
GB (1) GB9718455D0 (de)
WO (1) WO1999011785A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1534830T3 (da) * 2002-09-06 2011-02-14 Isogenica Ltd In vito-peptid-ekspressionsbibliotek
ES2327229T3 (es) 2002-11-09 2009-10-27 Immunocore Ltd. Presentacion del receptor de linfocitos t.
GB0418651D0 (en) * 2004-08-20 2004-09-22 Medical Res Council Method
WO2010127186A1 (en) 2009-04-30 2010-11-04 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
DK2556171T3 (en) 2010-04-05 2015-12-14 Prognosys Biosciences Inc Spatially CODED BIOLOGICAL ASSAYS
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20120258871A1 (en) * 2011-04-08 2012-10-11 Prognosys Biosciences, Inc. Peptide constructs and assay systems
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
WO2014060483A1 (en) 2012-10-17 2014-04-24 Spatial Transcriptomics Ab Methods and product for optimising localised or spatial detection of gene expression in a tissue sample
WO2014145047A1 (en) 2013-03-15 2014-09-18 Prognosys Biosciences, Inc. Methods for detecting peptide/mhc/tcr binding
US9868979B2 (en) 2013-06-25 2018-01-16 Prognosys Biosciences, Inc. Spatially encoded biological assays using a microfluidic device
WO2015070037A2 (en) 2013-11-08 2015-05-14 Prognosys Biosciences, Inc. Polynucleotide conjugates and methods for analyte detection
BR112016021004A2 (pt) 2014-03-14 2018-01-23 Immunocore Limited biblioteca de partículas; receptor de células t (tcr) isolado não natural; uso de uma biblioteca; método de obtenção de um receptor de células t que se liga especificamente a um antígeno de peptídeo; ácido nucleico; método de construção de uma biblioteca de partículas; método de obtenção de um receptor de células t que se liga especificamente a um antígeno de peptídeo; e partícula
EP4282977B1 (de) 2015-04-10 2024-06-05 10x Genomics Sweden AB Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
GB201516275D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516265D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516270D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516274D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516269D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
US20230102101A1 (en) * 2020-03-05 2023-03-30 Merck Sharp & Dohme Llc Human-like heavy chain antibody variable domain (vhh) display libraries
EP4567108A1 (de) * 2023-12-05 2025-06-11 Kutzner, Christoph Screening von zielpeptiden unter verwendung von fusionspolypeptiden

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
AU655912B2 (en) * 1989-03-17 1995-01-19 Salk Institute For Biological Studies, The Hormone response element compositions and assay
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
JPH06508511A (ja) 1990-07-10 1994-09-29 ケンブリッジ　アンティボディー　テクノロジー　リミティド 特異的な結合ペアーの構成員の製造方法
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE19646372C1 (de) * 1995-11-11 1997-06-19 Evotec Biosystems Gmbh Genotyp und Phänotyp koppelnde Verbindung
US6451527B1 (en) * 1997-08-29 2002-09-17 Selective Genetics, Inc. Methods using genetic package display for selecting internalizing ligands for gene delivery

Also Published As

Publication number Publication date
US7312074B1 (en) 2007-12-25
EP1009827B1 (de) 2004-11-24
CA2301826C (en) 2011-02-15
AU741002B2 (en) 2001-11-22
WO1999011785A1 (en) 1999-03-11
JP2001514853A (ja) 2001-09-18
DE69827810D1 (de) 2004-12-30
EP1009827A1 (de) 2000-06-21
DE69827810T2 (de) 2005-11-10
GB9718455D0 (en) 1997-11-05
US20080220981A1 (en) 2008-09-11
CA2301826A1 (en) 1999-03-11
US8735146B2 (en) 2014-05-27
AU8877898A (en) 1999-03-22
JP4221148B2 (ja) 2009-02-12

Similar Documents

Publication Publication Date Title
ATE283359T1 (de) Methode zum durchforsten von banken mittels chimären bindungspetiden
IL148021A0 (en) Novel b7-4 molecules and uses therefor
NO885659L (no) Mycobakterielle rekombinanter og peptider.
EP0804609A4 (de) NEUARTIGE AUF p53 ANSPRECHENDE GENE
AU7599500A (en) Novel gl50 molecules and uses therefor
EP1009752A4 (de) Neue moleküle aus der familieder tango-77-ähnlichen proteine und ihre verewendungen.
GR852940B (de)
ATE311443T1 (de) Methoden zur durchforstung (screenen) von proteinen
AU7093601A (en) Nucleic acid molecules encoding plant cell cycle proteins and uses therefor
EP1576157A4 (de) Fluoreszenzproteine aus copepoda-speziesund verfahren zur verwendung davon
IL173954A0 (en) Libraries of recombinant chimeric proteins and methods of generating the same
ZA200007619B (en) New peptide fragments for protein purification.
WO2002053589A3 (en) Nucleic acid molecules encoding dim interactors and uses therefor
WO2001081413A3 (en) Isolated human transporter proteins, nucleic acids and uses thereof
WO2002046406A3 (en) Human transporter proteins, nucleic acid molecules encoding them,and uses thereof
ES8700691A1 (es) Un metodo para sintetizar por adn recombinante un inhibidor de serin-proteasa con una unica cadena polipeptidica
DK1241186T4 (da) Humant vækststandsende specifikt gen-6 (gas-6) og nukleinsyrer kodende derfor
EP1251139A3 (de) Menschliches mindin-ähliches Protein und dafür kodierende Nukleinsäure
WO2002057310A3 (en) Human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002024910A3 (en) Isolated human transporter proteins, nucleic acid molecules encoding them, and uses thereof
WO2002024913A3 (en) 32612, a novel human peptide transporter and uses therefor
EP1247817A3 (de) Menschliches CD-23-ähliches Protein und dafür kodierende Nukleinsäure
WO2000053789A3 (de) Retrovirale expressionsvektoren auf der basis von herv-ltr-sequenzen
DK1241251T3 (da) Humant prostasin-lignende protein og nukleinsyrer kodende for samme
EP1249491A3 (de) Menschliches very long chain acyl-CoA synthase (VLCAS)-ähliches Protein und dafür codierende Nukleinsäure

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties