ATE283359T1 - Methode zum durchforsten von banken mittels chimären bindungspetiden - Google Patents

Methode zum durchforsten von banken mittels chimären bindungspetiden

Info

Publication number
ATE283359T1
ATE283359T1 AT98940455T AT98940455T ATE283359T1 AT E283359 T1 ATE283359 T1 AT E283359T1 AT 98940455 T AT98940455 T AT 98940455T AT 98940455 T AT98940455 T AT 98940455T AT E283359 T1 ATE283359 T1 AT E283359T1
Authority
AT
Austria
Prior art keywords
dna
fusion protein
carrier package
peptide
protein
Prior art date
Application number
AT98940455T
Other languages
English (en)
Inventor
Duncan Mcgregor
Original Assignee
Rowett Res Services Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rowett Res Services Ltd filed Critical Rowett Res Services Ltd
Application granted granted Critical
Publication of ATE283359T1 publication Critical patent/ATE283359T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1075—Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98940455T 1997-09-02 1998-09-02 Methode zum durchforsten von banken mittels chimären bindungspetiden ATE283359T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9718455.0A GB9718455D0 (en) 1997-09-02 1997-09-02 Chimeric binding peptide library screening method
PCT/GB1998/002630 WO1999011785A1 (en) 1997-09-02 1998-09-02 Chimeric binding peptide library screening method

Publications (1)

Publication Number Publication Date
ATE283359T1 true ATE283359T1 (de) 2004-12-15

Family

ID=10818309

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940455T ATE283359T1 (de) 1997-09-02 1998-09-02 Methode zum durchforsten von banken mittels chimären bindungspetiden

Country Status (9)

Country Link
US (2) US7312074B1 (de)
EP (1) EP1009827B1 (de)
JP (1) JP4221148B2 (de)
AT (1) ATE283359T1 (de)
AU (1) AU741002B2 (de)
CA (1) CA2301826C (de)
DE (1) DE69827810T2 (de)
GB (1) GB9718455D0 (de)
WO (1) WO1999011785A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003260786B2 (en) 2002-09-06 2008-03-13 Isogenica Limited In vitro peptide expression libraray
EP2048159B1 (de) 2002-11-09 2014-01-01 Immunocore Ltd. T-Zellrezeptorpresentation
GB0418651D0 (en) 2004-08-20 2004-09-22 Medical Res Council Method
US9085798B2 (en) 2009-04-30 2015-07-21 Prognosys Biosciences, Inc. Nucleic acid constructs and methods of use
KR101866401B1 (ko) 2010-04-05 2018-06-11 프로그노시스 바이오사이언스, 인코포레이티드 공간적으로 엔코딩된 생물학적 검정
US20190300945A1 (en) 2010-04-05 2019-10-03 Prognosys Biosciences, Inc. Spatially Encoded Biological Assays
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US20120258871A1 (en) * 2011-04-08 2012-10-11 Prognosys Biosciences, Inc. Peptide constructs and assay systems
GB201106254D0 (en) 2011-04-13 2011-05-25 Frisen Jonas Method and product
EP3901280B1 (de) 2012-10-17 2025-03-12 10x Genomics Sweden AB Verfahren und produkt zur optimierung einer lokalisierten oder räumlichen detektion einer genexpression in einer gewebeprobe
CA2907050C (en) 2013-03-15 2023-09-26 Prognosys Biosciences, Inc. Methods for detecting peptide/mhc/tcr binding
CN111500680B (zh) 2013-06-25 2024-04-16 普罗格诺西斯生物科学公司 检测样品中生物靶标的空间分布的方法和系统
US10288608B2 (en) 2013-11-08 2019-05-14 Prognosys Biosciences, Inc. Polynucleotide conjugates and methods for analyte detection
ES2740930T3 (es) 2014-03-14 2020-02-07 Immunocore Ltd Bibliotecas de TCR
EP4321627A3 (de) 2015-04-10 2024-04-17 10x Genomics Sweden AB Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
GB201516269D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516277D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR libraries
GB201516265D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516270D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516275D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516272D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
GB201516274D0 (en) 2015-09-15 2015-10-28 Adaptimmune Ltd And Immunocore Ltd TCR Libraries
US20230102101A1 (en) * 2020-03-05 2023-03-30 Merck Sharp & Dohme Llc Human-like heavy chain antibody variable domain (vhh) display libraries
EP4567108A1 (de) * 2023-12-05 2025-06-11 Kutzner, Christoph Screening von zielpeptiden unter verwendung von fusionspolypeptiden

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0463081B1 (de) 1989-03-17 1998-05-20 The Salk Institute For Biological Studies Zusammensetzung und testverfahren eines elementes als antwort auf ein hormon
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2139598T3 (es) 1990-07-10 2000-02-16 Medical Res Council Procedimientos para la produccion de miembros de parejas de union especifica.
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
DE19646372C1 (de) * 1995-11-11 1997-06-19 Evotec Biosystems Gmbh Genotyp und Phänotyp koppelnde Verbindung
US6451527B1 (en) * 1997-08-29 2002-09-17 Selective Genetics, Inc. Methods using genetic package display for selecting internalizing ligands for gene delivery

Also Published As

Publication number Publication date
EP1009827B1 (de) 2004-11-24
WO1999011785A1 (en) 1999-03-11
CA2301826A1 (en) 1999-03-11
DE69827810D1 (de) 2004-12-30
US8735146B2 (en) 2014-05-27
GB9718455D0 (en) 1997-11-05
US7312074B1 (en) 2007-12-25
CA2301826C (en) 2011-02-15
JP2001514853A (ja) 2001-09-18
AU8877898A (en) 1999-03-22
DE69827810T2 (de) 2005-11-10
US20080220981A1 (en) 2008-09-11
AU741002B2 (en) 2001-11-22
EP1009827A1 (de) 2000-06-21
JP4221148B2 (ja) 2009-02-12

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