ATE311443T1 - Methoden zur durchforstung (screenen) von proteinen - Google Patents

Methoden zur durchforstung (screenen) von proteinen

Info

Publication number
ATE311443T1
ATE311443T1 AT98940471T AT98940471T ATE311443T1 AT E311443 T1 ATE311443 T1 AT E311443T1 AT 98940471 T AT98940471 T AT 98940471T AT 98940471 T AT98940471 T AT 98940471T AT E311443 T1 ATE311443 T1 AT E311443T1
Authority
AT
Austria
Prior art keywords
methods
proteins
polypeptides
screening proteins
libraries
Prior art date
Application number
AT98940471T
Other languages
English (en)
Inventor
Francis Carr
Drive Balgownie
Graham Carter
Anita Hamilton
Fiona Adair
Steven Williams
Original Assignee
Biovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27585231&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE311443(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9718552.4A external-priority patent/GB9718552D0/en
Priority claimed from GBGB9719834.5A external-priority patent/GB9719834D0/en
Priority claimed from GBGB9720184.2A external-priority patent/GB9720184D0/en
Priority claimed from GBGB9720523.1A external-priority patent/GB9720523D0/en
Priority claimed from GBGB9720524.9A external-priority patent/GB9720524D0/en
Priority claimed from GBGB9720522.3A external-priority patent/GB9720522D0/en
Priority claimed from GBGB9720525.6A external-priority patent/GB9720525D0/en
Priority claimed from GBGB9801255.2A external-priority patent/GB9801255D0/en
Priority claimed from GBGB9803828.4A external-priority patent/GB9803828D0/en
Priority claimed from GBGB9807760.5A external-priority patent/GB9807760D0/en
Priority claimed from GBGB9811130.5A external-priority patent/GB9811130D0/en
Application filed by Biovation Ltd filed Critical Biovation Ltd
Publication of ATE311443T1 publication Critical patent/ATE311443T1/de
Application granted granted Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1041—Ribosome/Polysome display, e.g. SPERT, ARM
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT98940471T 1997-09-03 1998-09-03 Methoden zur durchforstung (screenen) von proteinen ATE311443T1 (de)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
GBGB9718552.4A GB9718552D0 (en) 1997-09-03 1997-09-03 Ribosome display
GBGB9719834.5A GB9719834D0 (en) 1997-09-18 1997-09-18 Ligand-directed screening for binding proteins
GBGB9720184.2A GB9720184D0 (en) 1997-09-24 1997-09-24 Biological DNA Library Screening Method
GBGB9720523.1A GB9720523D0 (en) 1997-09-29 1997-09-29 Ligand-directed screening for binding proteins
GBGB9720524.9A GB9720524D0 (en) 1997-09-29 1997-09-29 Selection of protein-protein interactions
GBGB9720522.3A GB9720522D0 (en) 1997-09-29 1997-09-29 Ribosome display
GBGB9720525.6A GB9720525D0 (en) 1997-09-29 1997-09-29 Biological dna library screening method
US7006397P 1997-12-30 1997-12-30
US7003797P 1997-12-30 1997-12-30
US7005097P 1997-12-30 1997-12-30
US7006297P 1997-12-30 1997-12-30
GBGB9801255.2A GB9801255D0 (en) 1998-01-22 1998-01-22 Section of protein-protein,protein-non protein and protein-defined protein interactions
GBGB9803828.4A GB9803828D0 (en) 1998-02-25 1998-02-25 Ribosome display
GBGB9807760.5A GB9807760D0 (en) 1998-04-14 1998-04-14 Disease associated protein modifications
GBGB9811130.5A GB9811130D0 (en) 1998-05-23 1998-05-23 Disease associated protein screening
PCT/GB1998/002649 WO1999011777A1 (en) 1997-09-03 1998-09-03 Methods for protein screening

Publications (1)

Publication Number Publication Date
ATE311443T1 true ATE311443T1 (de) 2005-12-15

Family

ID=27585231

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940471T ATE311443T1 (de) 1997-09-03 1998-09-03 Methoden zur durchforstung (screenen) von proteinen

Country Status (5)

Country Link
EP (1) EP1003853B1 (de)
JP (1) JP4524445B2 (de)
AT (1) ATE311443T1 (de)
CA (1) CA2302147C (de)
WO (1) WO1999011777A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2786787B1 (fr) * 1998-12-08 2002-04-19 Proteus Methode d'analyse in vitro d'un phenotype connu a partir d'un echantillon d'acides nucleiques
GB2361698B (en) * 2000-01-31 2003-06-25 Sense Proteomic Ltd Modification of DNA molecules
US7816098B2 (en) 2000-01-31 2010-10-19 Sense Proteomic Limited Methods of making and using a protein array
DK1268766T3 (da) 2000-03-31 2006-04-10 Cambridge Antibody Tech Forbedringer af ribosom-display
US7094568B2 (en) 2000-08-17 2006-08-22 Sense Proteomic Ltd. Method for producing proteins tagged at the N- or C-terminus
GB2384779B (en) * 2000-08-17 2004-09-29 Sense Proteomic Ltd Method for the production of tagged proteins
DE10043470B4 (de) * 2000-09-04 2006-01-19 Mpb Meltec Patent- Und Beteiligungsgesellschaft Mbh Verfahren zur Identifizierung von zellspezifischen Proteinen
ATE538380T1 (de) 2001-01-23 2012-01-15 Harvard College Nukleinsäure-programmierbare protein-arrays
GB0316314D0 (en) * 2003-07-12 2003-08-13 Univ Belfast Method
JP4564926B2 (ja) 2005-01-25 2010-10-20 エワ ユニバーシティ−インダストリー コラボレーション ファウンデーション ヒスタミン分泌能を有する欠失型ＩｇＥ依存的ヒスタミン放出因子、ＨＲＦ結合ペプチドおよびその利用方法
JP2008528668A (ja) 2005-02-03 2008-07-31 アンチトープ リミテッド ヒト抗体及びタンパク質
JP2006294014A (ja) * 2005-03-16 2006-10-26 Kumamoto Technology & Industry Foundation 解析プログラム、プロテインチップ、プロテインチップの製造方法、および、抗体カクテル
US8178316B2 (en) 2006-06-29 2012-05-15 President And Fellows Of Harvard College Evaluating proteins
US20090017455A1 (en) 2006-08-02 2009-01-15 Kwong Gabriel A Methods and systems for detecting and/or sorting targets
KR20130023091A (ko) * 2011-08-26 2013-03-07 (주)바이오니아 단백질 합성 키트, 자동추출장비를 이용한 단백질 발현 및 추출 방법
GB201214029D0 (en) * 2012-08-07 2012-09-19 Queen Mary & Westfield College method
JP7049756B2 (ja) * 2015-09-10 2022-04-07 国立大学法人埼玉大学 機能性ペプチドをコードするｄｎａの探索方法及び機能性ペプチドの調製方法
WO2020205426A1 (en) * 2019-03-29 2020-10-08 The Regents Of The University Of California Comprehensive identification of interacting protein targets using mrna display of uniform libraries
WO2021106814A1 (ja) * 2019-11-25 2021-06-03 国立研究開発法人理化学研究所 非リボソームｒｎａ含有試料の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0494955T3 (da) * 1989-10-05 1998-10-26 Optein Inc Cellefri syntese og isolering af hidtil ukendte gener og polypeptider
AU8498091A (en) * 1990-08-02 1992-03-02 Regents Of The University Of Colorado, The Systematic polypeptide evolution by reverse translation
DE4112440C1 (de) * 1991-04-16 1992-10-22 Diagen Institut Fuer Molekularbiologische Diagnostik Gmbh, 4000 Duesseldorf, De
WO1993003172A1 (en) * 1991-08-01 1993-02-18 University Research Corporation Systematic polypeptide evolution by reverse translation
WO1995011922A1 (en) * 1993-10-29 1995-05-04 Affymax Technologies N.V. In vitro peptide and antibody display libraries
US5516637A (en) * 1994-06-10 1996-05-14 Dade International Inc. Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
DE19646372C1 (de) * 1995-11-11 1997-06-19 Evotec Biosystems Gmbh Genotyp und Phänotyp koppelnde Verbindung
WO1998048008A1 (en) * 1997-04-23 1998-10-29 Plueckthun Andreas Methods for identifying nucleic acid molecules encoding (poly)peptides that interact with target molecules
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine

Also Published As

Publication number Publication date
EP1003853B1 (de) 2005-11-30
JP4524445B2 (ja) 2010-08-18
EP1003853A1 (de) 2000-05-31
WO1999011777A1 (en) 1999-03-11
JP2001514850A (ja) 2001-09-18
CA2302147C (en) 2008-05-13
CA2302147A1 (en) 1999-03-11

Similar Documents

Publication Publication Date Title
ATE311443T1 (de) Methoden zur durchforstung (screenen) von proteinen
PT859841E (pt) Bibliotecas de proteinas/ (poli) peptidos
DE69938867D1 (de) Verfahren und verwendung von anordungen von proteinfixierungsmitteln
DE60335000D1 (de) In vitro peptid-expressionsbank
IL130036A0 (en) Survivin a protein that inhibits cellular apoptosis and its modulation
PT765389E (pt) Novos sistemas celulares tendo interaccao especifica de pares de peptidicos que se ligam mutuamente
DE69830497D1 (de) Bibliothek für die in vitro expression von peptiden oder proteinen
ATE282631T1 (de) Sh3-bindender peptide von cortactin und deren verwendung
ATE352618T1 (de) Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält
WO1998012328A3 (en) Human bad polypeptides, encoding nucleic acids and methods of use
DE69738586D1 (de) Hohe expressionsrate von proteinen
DK1051500T3 (da) Diagnose og behandling af AUR1- og/eller AUR2-relaterede sygdomme
CY1107629T1 (el) Πρωτεïνη crsp (πλουσιες σε κυστεïνη εκκρινομενες πρωτεïνες) μορια νουκλεϊνικου οξεως που τις κωδικοποιουν και χρησεις τους
DE69833014D1 (de) Menschliche toll homologen
ATE135371T1 (de) Mit akuter pankreatitis assoziiertes protein, mittel zur diagnose von akuter pankreatitis
DE69827810D1 (de) Methode zum durchforsten von banken mittels chimären bindungspetiden
EP1009752A4 (de) Neue moleküle aus der familieder tango-77-ähnlichen proteine und ihre verewendungen.
BR9912455A (pt) ácidos nucléicos codificadores de proteìnas envolvidas em transdução sensória
ATE363070T1 (de) Auswertung von biologischen mitteln in lebenden zielzellen
DK1082423T3 (da) Cyclin E2-gener og -proteiner
FI971896A7 (fi) BMP-tyyppi II-reseptoria koodaava cDNA
GB9816514D0 (en) Novel method
WO2002005843A3 (en) Human rrp sequences and methods of use
DE69831141D1 (de) Z2-19a, ein menschliches homolog von dem protein 2-19
AU2001238064A1 (en) 18477, a human protein kinase and uses therefor

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties