ATE283364T1 - Mehrzweck-antikörperderivate - Google Patents

Mehrzweck-antikörperderivate

Info

Publication number
ATE283364T1
ATE283364T1 AT99907419T AT99907419T ATE283364T1 AT E283364 T1 ATE283364 T1 AT E283364T1 AT 99907419 T AT99907419 T AT 99907419T AT 99907419 T AT99907419 T AT 99907419T AT E283364 T1 ATE283364 T1 AT E283364T1
Authority
AT
Austria
Prior art keywords
heterodimerization
molecules
vhch1
chosen
class
Prior art date
Application number
AT99907419T
Other languages
English (en)
Inventor
Reinhilde Schoonjans
Nico Mertens
Walter Fiers
Roland Contreras
Original Assignee
Vlaams Interuniv Inst Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vlaams Interuniv Inst Biotech filed Critical Vlaams Interuniv Inst Biotech
Application granted granted Critical
Publication of ATE283364T1 publication Critical patent/ATE283364T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT99907419T 1998-01-23 1999-01-25 Mehrzweck-antikörperderivate ATE283364T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98200193 1998-01-23
PCT/EP1999/000477 WO1999037791A1 (en) 1998-01-23 1999-01-25 Multipurpose antibody derivatives

Publications (1)

Publication Number Publication Date
ATE283364T1 true ATE283364T1 (de) 2004-12-15

Family

ID=8233317

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99907419T ATE283364T1 (de) 1998-01-23 1999-01-25 Mehrzweck-antikörperderivate

Country Status (10)

Country Link
US (1) US6809185B1 (de)
EP (1) EP1049787B1 (de)
AT (1) ATE283364T1 (de)
AU (1) AU2719099A (de)
CA (1) CA2317727C (de)
DE (1) DE69922159T2 (de)
DK (1) DK1049787T3 (de)
ES (1) ES2234241T3 (de)
PT (1) PT1049787E (de)
WO (1) WO1999037791A1 (de)

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