ATE283487T1 - Verfahren zur diagnose oder prognose von altersbedingter maculadegeneration - Google Patents
Verfahren zur diagnose oder prognose von altersbedingter maculadegenerationInfo
- Publication number
- ATE283487T1 ATE283487T1 AT00967639T AT00967639T ATE283487T1 AT E283487 T1 ATE283487 T1 AT E283487T1 AT 00967639 T AT00967639 T AT 00967639T AT 00967639 T AT00967639 T AT 00967639T AT E283487 T1 ATE283487 T1 AT E283487T1
- Authority
- AT
- Austria
- Prior art keywords
- age
- macular degeneration
- related macular
- subject
- activity
- Prior art date
Links
- 206010064930 age-related macular degeneration Diseases 0.000 title abstract 7
- 208000002780 macular degeneration Diseases 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title 1
- 238000004393 prognosis Methods 0.000 title 1
- 230000000694 effects Effects 0.000 abstract 4
- 102000009091 Amyloidogenic Proteins Human genes 0.000 abstract 2
- 108010048112 Amyloidogenic Proteins Proteins 0.000 abstract 2
- 102000012192 Cystatin C Human genes 0.000 abstract 2
- 108010061642 Cystatin C Proteins 0.000 abstract 2
- 238000012544 monitoring process Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 238000013518 transcription Methods 0.000 abstract 2
- 230000035897 transcription Effects 0.000 abstract 2
- 108700026220 vif Genes Proteins 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003862 health status Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99117198 | 1999-09-01 | ||
| EP00101921 | 2000-02-01 | ||
| PCT/EP2000/008554 WO2001016364A2 (en) | 1999-09-01 | 2000-09-01 | Methods of diagnosing or prognosticating age-related macular degeneration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE283487T1 true ATE283487T1 (de) | 2004-12-15 |
Family
ID=26070484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00967639T ATE283487T1 (de) | 1999-09-01 | 2000-09-01 | Verfahren zur diagnose oder prognose von altersbedingter maculadegeneration |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20070117122A1 (de) |
| EP (1) | EP1210464B1 (de) |
| AT (1) | ATE283487T1 (de) |
| DE (1) | DE60016242T2 (de) |
| WO (1) | WO2001016364A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US8088587B2 (en) | 2005-03-04 | 2012-01-03 | Vanderbilt University | Genetic variants increase the risk of age-related macular degeneration |
| CA2725709A1 (en) * | 2005-06-08 | 2006-12-14 | University Of Pittsburgh - Of The Commonwealth System Of Higher Educatio N | Susceptibility genes for age-related maculopathy (arm) on chromosome 10q26 |
| WO2007056111A1 (en) * | 2005-11-02 | 2007-05-18 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method evolved for recognition and testing of age related macular degeneration (mert-armd) |
| PT1976877E (pt) | 2005-11-30 | 2014-04-29 | Abbvie Inc | Anticorpos monoclonais contra proteína beta-amilóide e suas utilizações |
| BRPI0619249A2 (pt) | 2005-11-30 | 2011-09-20 | Abbott Lab | anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (de) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Verfahren zur behandlung von amyloidosen |
| WO2008110283A2 (en) * | 2007-03-14 | 2008-09-18 | Dsm Ip Assets B.V. | Method for prevention of age-related macular degeneration (amd) |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| EP2205631B1 (de) * | 2007-10-05 | 2016-11-23 | Genentech, Inc. | Methoden und zusammensetzungen zur diagnose und behandlung von amyloidose |
| EP2586795B1 (de) | 2007-10-05 | 2018-05-16 | Genentech, Inc. | Verwendung eines Anti-Amyloid-Beta-Antikörpers bei Augenkrankheiten |
| EP2558494B1 (de) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta-bindende proteine |
| AU2011282536B2 (en) | 2010-07-30 | 2015-12-24 | Ac Immune S.A. | Safe and functional humanized anti beta-amyloid antibody |
| CN105348387B (zh) | 2010-08-14 | 2020-08-25 | Abbvie 公司 | β淀粉样蛋白结合蛋白 |
| EP2497490A1 (de) * | 2011-03-07 | 2012-09-12 | Bioquanta | Verfahren zur Diagnose und/oder Behandlung von Sterilität |
| JP5721150B2 (ja) * | 2013-03-14 | 2015-05-20 | 学校法人 埼玉医科大学 | 加齢黄斑変性症の発症リスクの予測方法 |
| EP4311574A1 (de) * | 2022-07-29 | 2024-01-31 | Chung-Ang University Industry-Academic Cooperation | Prävention und behandlung von altersbedingter makuladegeneration durch unterdrückung der cathepsin-s-expression |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3724581A1 (de) * | 1987-07-24 | 1989-02-02 | Gruenenthal Gmbh | Dna-sequenzen, die fuer proteine mit den biologischen eigenschaften des cystatin c codieren, herstellung dieser dna-sequenzen, expression des cystatin c sowie dieses enthaltende pharmazeutische zubereitungen |
| US5231000A (en) * | 1987-10-08 | 1993-07-27 | The Mclean Hospital | Antibodies to A4 amyloid peptide |
| US5262332A (en) * | 1989-04-05 | 1993-11-16 | Brigham And Women's Hospital | Diagnostic method for Alzheimer's disease: examination of non-neural tissue |
| CA2079880A1 (en) * | 1990-04-24 | 1991-10-25 | William E. Van Nostrand | Purification, detection and methods of use of protease nexin-2 |
| US5981471A (en) * | 1997-02-06 | 1999-11-09 | Entremed, Inc. | Compositions and methods for inhibiting cellular proliferation |
-
2000
- 2000-09-01 AT AT00967639T patent/ATE283487T1/de not_active IP Right Cessation
- 2000-09-01 DE DE60016242T patent/DE60016242T2/de not_active Expired - Fee Related
- 2000-09-01 WO PCT/EP2000/008554 patent/WO2001016364A2/en not_active Ceased
- 2000-09-01 EP EP00967639A patent/EP1210464B1/de not_active Expired - Lifetime
-
2006
- 2006-09-25 US US11/526,188 patent/US20070117122A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001016364A3 (en) | 2002-03-14 |
| DE60016242T2 (de) | 2005-12-01 |
| DE60016242D1 (de) | 2004-12-30 |
| EP1210464A2 (de) | 2002-06-05 |
| EP1210464B1 (de) | 2004-11-24 |
| WO2001016364A2 (en) | 2001-03-08 |
| US20070117122A1 (en) | 2007-05-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1210464 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |