ATE286253T1 - Methoden zur diagnose oder prognose der alzheimerschen krankheit - Google Patents

Methoden zur diagnose oder prognose der alzheimerschen krankheit

Info

Publication number
ATE286253T1
ATE286253T1 AT99971091T AT99971091T ATE286253T1 AT E286253 T1 ATE286253 T1 AT E286253T1 AT 99971091 T AT99971091 T AT 99971091T AT 99971091 T AT99971091 T AT 99971091T AT E286253 T1 ATE286253 T1 AT E286253T1
Authority
AT
Austria
Prior art keywords
disease
alzheimer
subject
activity
level
Prior art date
Application number
AT99971091T
Other languages
English (en)
Inventor
Roger Nitsch
John Growdon
Original Assignee
Evotec Neurosciences Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP99101377A external-priority patent/EP1024364A1/de
Application filed by Evotec Neurosciences Gmbh filed Critical Evotec Neurosciences Gmbh
Application granted granted Critical
Publication of ATE286253T1 publication Critical patent/ATE286253T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Medical Treatment And Welfare Office Work (AREA)
AT99971091T 1998-10-23 1999-10-22 Methoden zur diagnose oder prognose der alzheimerschen krankheit ATE286253T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10545898P 1998-10-23 1998-10-23
US10743498P 1998-11-06 1998-11-06
EP99101377A EP1024364A1 (de) 1999-01-26 1999-01-26 Methoden zur Diagnose oder Prognose von Alzheimer
PCT/EP1999/008023 WO2000025138A2 (en) 1998-10-23 1999-10-22 Methods of diagnosing or prognosing alzheimer's disease

Publications (1)

Publication Number Publication Date
ATE286253T1 true ATE286253T1 (de) 2005-01-15

Family

ID=27239924

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99971091T ATE286253T1 (de) 1998-10-23 1999-10-22 Methoden zur diagnose oder prognose der alzheimerschen krankheit

Country Status (8)

Country Link
US (1) US20090023145A1 (de)
EP (1) EP1123509B1 (de)
JP (1) JP2002531063A (de)
AT (1) ATE286253T1 (de)
AU (1) AU1153300A (de)
DE (1) DE69922987T2 (de)
ES (1) ES2235550T3 (de)
WO (1) WO2000025138A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506564B1 (en) 1996-07-29 2003-01-14 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
GB0012123D0 (en) * 2000-05-20 2000-07-12 Univ Dundee Alzheimer's disease assay
US20020025527A1 (en) * 2000-07-03 2002-02-28 Fiona Crawford Methods and assays for diagnosing alzheimer's disease
EP1394549A1 (de) 2002-08-23 2004-03-03 Bayer HealthCare AG Biomarker zur Diagnose von Alzheimer Erkrankung
EP2221620B1 (de) * 2002-08-23 2013-10-02 Bayer Pharma Aktiengesellschaft Biomarker zur Diagnose von Alzheimer
AU2003283303A1 (en) * 2002-11-08 2004-06-07 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human phosphodiesterase 4b (pde4b)
EP1426767A1 (de) * 2002-12-04 2004-06-09 Bayer HealthCare AG Diagnostika und Therapeutika für mit humanen Phosphodiesterase 4c (PDE4C) assozierten Krankheiten
EP1694816B1 (de) * 2003-11-07 2013-08-28 Ciphergen Biosystems, Inc. Biomarker für morbus alzheimer
ES2559859T3 (es) * 2007-05-16 2016-02-16 The Brigham And Women's Hospital, Inc. Tratamiento de sinucleinopatías
KR102572009B1 (ko) * 2020-10-21 2023-08-29 순천향대학교 산학협력단 시스타틴 c를 포함하는 퇴행성 신경 질환 진단용 바이오마커 조성물 및 이의 용도
CN115612728A (zh) * 2021-07-16 2023-01-17 深圳先进技术研究院 一种神经退行性疾病标志物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2711201C3 (de) * 1977-03-15 1980-06-12 7800 Freiburg Verfahren zur Überprüfen der Harnstoffwerte im menschlichen Körper

Also Published As

Publication number Publication date
WO2000025138A2 (en) 2000-05-04
DE69922987T2 (de) 2006-05-04
EP1123509B1 (de) 2004-12-29
AU1153300A (en) 2000-05-15
US20090023145A1 (en) 2009-01-22
EP1123509A2 (de) 2001-08-16
DE69922987D1 (de) 2005-02-03
JP2002531063A (ja) 2002-09-24
ES2235550T3 (es) 2005-07-01
WO2000025138A3 (en) 2000-08-24

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