ATE283707T1 - Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem - Google Patents

Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem

Info

Publication number
ATE283707T1
ATE283707T1 AT99900173T AT99900173T ATE283707T1 AT E283707 T1 ATE283707 T1 AT E283707T1 AT 99900173 T AT99900173 T AT 99900173T AT 99900173 T AT99900173 T AT 99900173T AT E283707 T1 ATE283707 T1 AT E283707T1
Authority
AT
Austria
Prior art keywords
antibacterial composition
topical application
application containing
faropenem
containing faropenem
Prior art date
Application number
AT99900173T
Other languages
English (en)
Inventor
Masaaki Nomura
Hiromi Sumikawa
Osamu Sugita
Original Assignee
Daiichi Suntory Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Suntory Pharma Co Ltd filed Critical Daiichi Suntory Pharma Co Ltd
Application granted granted Critical
Publication of ATE283707T1 publication Critical patent/ATE283707T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99900173T 1998-01-13 1999-01-12 Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem ATE283707T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP484598 1998-01-13
PCT/JP1999/000068 WO1999036098A1 (en) 1998-01-13 1999-01-12 Antibacterial composition for topical administration containing antibiotics

Publications (1)

Publication Number Publication Date
ATE283707T1 true ATE283707T1 (de) 2004-12-15

Family

ID=11595031

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99900173T ATE283707T1 (de) 1998-01-13 1999-01-12 Antibakterille zusammensetzung zur topischen anwendung, enthaltend faropenem

Country Status (7)

Country Link
US (3) US6365635B1 (de)
EP (1) EP0966974B1 (de)
KR (1) KR20000076105A (de)
CN (1) CN1133428C (de)
AT (1) ATE283707T1 (de)
DE (1) DE69922296T2 (de)
WO (1) WO1999036098A1 (de)

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DE60025503T2 (de) * 1999-09-17 2006-09-07 Daiichi Asubio Pharma Co., Ltd. Pharmazeutische Zusammensetzungen, die Faropenem-Natrium und eine Diaminoacetat Verbindung zur Verbesserung der Magen-Darm-Trakt Absorption enthalten
EP1138333B1 (de) * 1999-10-12 2004-02-25 Daiichi Suntory Pharma Co., Ltd. Arzneimittel zur oralen verabreichung
ATE395920T1 (de) * 1999-12-28 2008-06-15 Teikoku Seiyaku Kk Wirkstoffe gegen pruritus zum äusserlichen gebrauch
JP4653282B2 (ja) * 2000-05-23 2011-03-16 昭和薬品化工株式会社 ミノサイクリン含有組成物
CA2450728C (en) 2001-06-15 2011-04-26 Forty Eight Shelf (80) Limited Composition for the treatment of diseases which affect animals' hooves
US7220431B2 (en) * 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
US7494980B2 (en) * 2003-03-10 2009-02-24 The United States Of America As Represented By The Secretary Of The Army Antimicrobial peptide and methods of use thereof
US8778889B2 (en) * 2003-03-10 2014-07-15 The United States Of America As Represented By The Secretary Of The Army Antimicrobial decapeptide oral hygiene treatment
US20050123576A1 (en) * 2003-12-03 2005-06-09 Ilana Lavon Mupirocin compositions for topical use, an improved process of making same and methods of using same
US20060029674A1 (en) * 2004-04-09 2006-02-09 Sever Nancy E Stable amorphous Cefdinir
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
ES2415362T3 (es) * 2005-04-08 2013-07-25 Mie University Agente externo para tratar heridas
US20090275746A1 (en) * 2006-07-28 2009-11-05 Hetero Drugs Limited Solid faropenem free acid
EP2097067A2 (de) * 2006-12-05 2009-09-09 University Of The Witwatersrand, Johannesburg Heterogen konfiguriertes multiteilchenförmiges gastrointestinales arzneiabgabesystem
CA2734687A1 (en) * 2008-08-18 2010-02-25 Nanotherapeutics, Inc. Topical hydrogel composition
JP2013538868A (ja) * 2010-10-08 2013-10-17 ヘルパービー セラピューティクス リミテッド 新規な組成物
WO2014025412A1 (en) * 2012-08-06 2014-02-13 Isp Investments Inc. Eco-friendly non-aqueous antimicrobial composition comprising tropolone with 1,3-propanediol and/or sorbitan caprylate
US20170239277A1 (en) * 2016-02-23 2017-08-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US20170333467A1 (en) 2015-12-18 2017-11-23 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11684567B2 (en) 2015-08-05 2023-06-27 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11690815B2 (en) 2015-08-05 2023-07-04 Cmpd Licensing Llc Hyperkeratotic skin condition treatments and compositions
US11793783B2 (en) 2015-08-05 2023-10-24 Cmpd Licensing, Llc Compositions and methods for treating an infection
US10898455B2 (en) 2016-01-07 2021-01-26 Cmpd Licensing, Llc Urea cream formulations
US11278590B2 (en) 2015-08-05 2022-03-22 Cmpd Licensing, Llc Compositions and methods for treating nail infections
US10898491B2 (en) 2015-12-18 2021-01-26 Cmpd Licensing, Llc Compositions and methods for treating an infection
US11446236B2 (en) 2015-08-05 2022-09-20 Cmpd Licensing, Llc Topical antimicrobial compositions and methods of formulating the same
US11202788B2 (en) 2019-08-22 2021-12-21 Nanopharmaceutics, Inc. Topical doxycycline hydrogel with improved long-term stability

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US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
JPS5625110A (en) 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
IL58576A (en) 1978-12-18 1985-12-31 Bristol Myers Co 2-substituted and 2,6-disubstituted penem compounds,their preparation and pharmaceutical compositions containing them
US4683226A (en) * 1979-08-01 1987-07-28 Schering Corporation 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids
US4411906A (en) * 1981-11-25 1983-10-25 Schering Corporation (5R,6S,8R)-6-(1-Hydroxyethyl)-2-(2-fluoroethylthio)-penem-3-carboxylates
US4388310A (en) * 1982-03-01 1983-06-14 Merck & Co., Inc. 6-Amido-2-S-oxides of substituted 2-organothio-pen-2-em-3-carboxylic acids
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US4743598A (en) * 1982-12-06 1988-05-10 Schering Corporation Antibacterial 2-(azacycloalkyl) penems
JPS61130228A (ja) 1984-11-29 1986-06-18 Sunstar Inc ミノサイクリンを安定に配合した組成物
JPH0234325B2 (ja) 1985-11-22 1990-08-02 Sansutaa Kk Shishushitsukanchiryoyososeibutsu
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JPH075463B2 (ja) 1985-03-09 1995-01-25 サントリー株式会社 抗菌剤
JP2526046B2 (ja) 1986-12-26 1996-08-21 サントリー株式会社 ペネム誘導体、その製造法およびその用途
JP2852687B2 (ja) 1990-04-27 1999-02-03 富山化学工業株式会社 歯周ポケット用徐放性口腔用軟膏
ATE186053T1 (de) * 1990-08-20 1999-11-15 Suntory Ltd Antibakterielle penem-esterderivate
ATE217195T1 (de) * 1991-02-01 2002-05-15 Suntory Ltd Verwendung von cilastatin, glutathione und n- acetyl-l-cysteine zur herstellung eines arzneimittels zur verbesserung der resorption von carbapenem oder penem antibiotika im magen-darm- trakt
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US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes

Also Published As

Publication number Publication date
DE69922296D1 (de) 2005-01-05
CN1256633A (zh) 2000-06-14
US6365635B1 (en) 2002-04-02
US20020035160A1 (en) 2002-03-21
DE69922296T2 (de) 2005-10-27
EP0966974B1 (de) 2004-12-01
WO1999036098A1 (en) 1999-07-22
EP0966974A1 (de) 1999-12-29
EP0966974A4 (de) 2003-05-21
US20020142040A1 (en) 2002-10-03
CN1133428C (zh) 2004-01-07
KR20000076105A (ko) 2000-12-26
US20040151743A1 (en) 2004-08-05

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties