DK1142573T3 - Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen - Google Patents
Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalenInfo
- Publication number
- DK1142573T3 DK1142573T3 DK00961049T DK00961049T DK1142573T3 DK 1142573 T3 DK1142573 T3 DK 1142573T3 DK 00961049 T DK00961049 T DK 00961049T DK 00961049 T DK00961049 T DK 00961049T DK 1142573 T3 DK1142573 T3 DK 1142573T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical compositions
- gastrointestinal tract
- acetate compound
- faropenem sodium
- tract absorption
- Prior art date
Links
- -1 diamine acetate compound Chemical class 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 title 1
- MOGICMVNWAUWMK-HIXRZVNASA-L disodium;(5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate;pentahydrate Chemical compound O.O.O.O.O.[Na+].[Na+].S([C@@H]1[C@H](C(N1C=1C([O-])=O)=O)[C@H](O)C)C=1[C@H]1CCCO1.S([C@@H]1[C@H](C(N1C=1C([O-])=O)=O)[C@H](O)C)C=1[C@H]1CCCO1 MOGICMVNWAUWMK-HIXRZVNASA-L 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 229960000379 faropenem Drugs 0.000 title 1
- 210000001035 gastrointestinal tract Anatomy 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 150000002961 penems Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26463799 | 1999-09-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1142573T3 true DK1142573T3 (da) | 2006-04-10 |
Family
ID=17406127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00961049T DK1142573T3 (da) | 1999-09-17 | 2000-09-18 | Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6531508B1 (da) |
| EP (1) | EP1142573B1 (da) |
| JP (1) | JP4745573B2 (da) |
| KR (1) | KR20010101030A (da) |
| CN (1) | CN1198611C (da) |
| AT (1) | ATE315395T1 (da) |
| CA (1) | CA2351673A1 (da) |
| DE (1) | DE60025503T2 (da) |
| DK (1) | DK1142573T3 (da) |
| ES (1) | ES2256035T3 (da) |
| WO (1) | WO2001021175A1 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE285821T1 (de) * | 1999-10-08 | 2005-01-15 | Affinium Pharm Inc | Fab i inhibitoren |
| CA2444597A1 (en) * | 2001-04-06 | 2002-10-06 | Affinium Pharmaceuticals, Inc. | Fab i inhibitors |
| EP1575951B1 (en) | 2002-12-06 | 2014-06-25 | Debiopharm International SA | Heterocyclic compounds, methods of making them and their use in therapy |
| DE602004016831D1 (de) | 2003-03-17 | 2008-11-13 | Affinium Pharm Inc | Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend |
| US20050069590A1 (en) * | 2003-09-30 | 2005-03-31 | Buehler Gail K. | Stable suspensions for medicinal dosages |
| EP2848614A3 (en) | 2004-06-04 | 2015-07-29 | Debiopharm International SA | Acrylamide derivatives as antibiotic agents |
| KR101420445B1 (ko) * | 2005-08-31 | 2014-07-16 | 아브락시스 바이오사이언스, 엘엘씨 | 수 난용성 제약학적 약제 및 항균제를 포함하는 조성물 |
| EP1973902A2 (en) * | 2005-12-05 | 2008-10-01 | Affinium Pharmaceuticals, Inc. | 3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents |
| EP2687533B1 (en) | 2006-07-20 | 2017-07-19 | Debiopharm International SA | Acrylamide derivatives as FAB I inhibitors |
| US20090275746A1 (en) * | 2006-07-28 | 2009-11-05 | Hetero Drugs Limited | Solid faropenem free acid |
| CN101129381B (zh) * | 2006-08-25 | 2012-02-01 | 天津和美生物技术有限公司 | 含β-内酰胺类抗生素和离子螯合剂的抗生素复方 |
| WO2008098374A1 (en) | 2007-02-16 | 2008-08-21 | Affinium Pharmaceuticals, Inc. | Salts, prodrugs and polymorphs of fab i inhibitors |
| US9169477B2 (en) | 2012-01-27 | 2015-10-27 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Compositions and methods for immunization against bacteria expressing a carbapenemase |
| SI2861608T1 (sl) | 2012-06-19 | 2019-08-30 | Debiopharm International Sa | Derivati predzdravila (E)-N-metil-N-((3-metilbenzofuran-2-IL)metil)- 3-(7-okso-5,6,7,8-tetrahidro-1 ,8-nafthiridin-3-il)akrilamid |
| BR122023021456A2 (pt) | 2016-02-26 | 2024-02-20 | Debiopharm International S.A. | Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica |
| LT3923914T (lt) | 2019-02-14 | 2023-07-25 | Debiopharm International S.A. | Afabicino kompozicija, jos gamybos būdas |
| CN113939306B (zh) | 2019-06-14 | 2024-07-19 | 德彪药业国际股份公司 | 用于治疗涉及生物膜的细菌感染的药物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD29756A (da) * | ||||
| GB909365A (en) | 1960-04-28 | 1962-10-31 | Horner Frank W Ltd | Orally ingestible solid penicillin compositions |
| GB1061426A (en) | 1964-05-22 | 1967-03-15 | Olin Mathieson | Water-soluble penicillin composition |
| US4504485A (en) * | 1983-04-04 | 1985-03-12 | Schering Corporation | 5R,6S,8R-6-(1-Hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylic acid |
| JP2514249B2 (ja) | 1989-05-23 | 1996-07-10 | 帝人株式会社 | 安定化されたカルシトニン類医薬組成物 |
| ES2176179T3 (es) | 1991-02-01 | 2002-12-01 | Suntory Ltd | Composiciones antibacterianas orales y metodo para la mejora de la absorcion gastrointestinal de los antibioticos de penemo o carbapemo. |
| JPH0769887A (ja) | 1993-07-09 | 1995-03-14 | Takeda Chem Ind Ltd | ペネム化合物含有固形組成物、その製造法および剤 |
| JPH0812675A (ja) | 1994-06-30 | 1996-01-16 | Lederle Japan Ltd | ２−［（４−ハロゲン置換フェニル）チオ］−カルバペネム誘導体 |
| EP0966974B1 (en) * | 1998-01-13 | 2004-12-01 | Daiichi Suntory Pharma Co., Ltd. | Antibacterial composition for topical administration containing faropenem |
-
2000
- 2000-09-18 DE DE60025503T patent/DE60025503T2/de not_active Expired - Fee Related
- 2000-09-18 ES ES00961049T patent/ES2256035T3/es not_active Expired - Lifetime
- 2000-09-18 KR KR1020017006262A patent/KR20010101030A/ko not_active Abandoned
- 2000-09-18 CN CNB008022372A patent/CN1198611C/zh not_active Expired - Fee Related
- 2000-09-18 AT AT00961049T patent/ATE315395T1/de not_active IP Right Cessation
- 2000-09-18 EP EP00961049A patent/EP1142573B1/en not_active Expired - Lifetime
- 2000-09-18 US US09/856,094 patent/US6531508B1/en not_active Expired - Fee Related
- 2000-09-18 WO PCT/JP2000/006346 patent/WO2001021175A1/ja not_active Ceased
- 2000-09-18 CA CA002351673A patent/CA2351673A1/en not_active Abandoned
- 2000-09-18 DK DK00961049T patent/DK1142573T3/da active
- 2000-09-18 JP JP2001524601A patent/JP4745573B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1142573B1 (en) | 2006-01-11 |
| EP1142573A1 (en) | 2001-10-10 |
| CN1327385A (zh) | 2001-12-19 |
| CA2351673A1 (en) | 2001-03-29 |
| US6531508B1 (en) | 2003-03-11 |
| ATE315395T1 (de) | 2006-02-15 |
| JP4745573B2 (ja) | 2011-08-10 |
| ES2256035T3 (es) | 2006-07-16 |
| DE60025503T2 (de) | 2006-09-07 |
| KR20010101030A (ko) | 2001-11-14 |
| DE60025503D1 (de) | 2006-04-06 |
| WO2001021175A1 (fr) | 2001-03-29 |
| CN1198611C (zh) | 2005-04-27 |
| EP1142573A4 (en) | 2002-07-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1142573T3 (da) | Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen | |
| DE60142891D1 (de) | Azetidinderivate enthaltende pharmazeutische zusammensetzungen, die azetidinderivate und deren herstellung | |
| EE200100594A (et) | Uudsed ravimikompositsioonid, mis põhinevad antikolinergiliselt toimivatel ühenditel ja ß-mimeetikumidel | |
| ATE303149T1 (de) | Orale pharmazeutische zusammensetzung aus cefpodoxim-proxetil | |
| DE60204403D1 (de) | Feste orale Dosierungsform von Simethicon | |
| IL157741A0 (en) | Pharmaceutical compositions containing an antihyperplastic active agent | |
| EE200200486A (et) | Farmatseutilised kompositsioonid, mis sisaldavad 3-aminoasetidiini derivaate, uued derivaadid ja nende valmistamismeetodid | |
| NO20042739L (no) | Farmasoytiske sammensetninger av 5,6,14-triazatetracyklo(10.3.1.0(2,11).0(4,9))-heksadeca-2(11)3,5,7,9-pentan | |
| SE0102315D0 (sv) | Compounds | |
| EE200200357A (et) | Ravimaine suurenenud kontsentratsioone andvad farmatseutilised kompositsioonid | |
| NO20043702L (no) | 8-azaprostaglandinderivatforbindelser og legemidler inneholdende forbindelsene som den aktive bestanddel | |
| DE59707812D1 (de) | Opioidantagonisthaltige galenische formulierung | |
| NO20040564L (no) | Karboksylsyrederivatforbindelser og legemidler omfattende disse forbindelser som den aktive bestanddel | |
| IL159725A0 (en) | Pharmaceutical compositions containing benzimidazole derivatives | |
| DK1498411T3 (da) | Diketohydrazinderivatforbindelser og medikamenter indeholdende forbindelserne som den aktive bestanddel | |
| DK1557415T3 (da) | Heterocykliske forbindelser og antitumorlægemidler indeholdende samme som den aktive ingrediens | |
| ATE399537T1 (de) | Pharmazeutische zusammensetzungen mit atorvastatin, hergestellt ohne granulation | |
| DE60312049D1 (de) | Stabilisierte pharmazeutische zusammensetzung enthaltend einen amorphen wirkstoff | |
| PT1458377E (pt) | Composicoes farmaceuticas contendo tegaserod | |
| EE200200342A (et) | Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend | |
| DE60211183D1 (de) | Pharmazeutische zusammensetzung enthaltend lumiracoxib | |
| NO20021898L (no) | Farmasoytisk sammensetning inneholdende ciclesonid for applikasjon til mukosa | |
| ATE350016T1 (de) | Bicalutamid enthaltende pharmazeutische zusammensetzung | |
| IL174336A0 (en) | Carboxylic acid compounds and medicinal compositions containing the same as the active ingredient | |
| ATE412404T1 (de) | Stabile orale pharmazeutische zusammensetzungen von buprenorphin und salz davon |