DK1142573T3 - Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen - Google Patents

Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen

Info

Publication number: DK1142573T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical compositions; gastrointestinal tract; acetate compound; faropenem sodium; tract absorption
Prior art date: 1999-09-17

Application number

DK00961049T

Other languages

English (en)

Inventor

Masaaki Nomura

Osamu Sugita

Original Assignee

Daiichi Asubio Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-09-17

Filing date

2000-09-18

Publication date

2006-04-10

2000-09-18 Application filed by Daiichi Asubio Pharma Co Ltd filed Critical Daiichi Asubio Pharma Co Ltd

2006-04-10 Application granted granted Critical

2006-04-10 Publication of DK1142573T3 publication Critical patent/DK1142573T3/da

Links

-1 diamine acetate compound Chemical class 0.000 title abstract 2
238000010521 absorption reaction Methods 0.000 title 1
MOGICMVNWAUWMK-HIXRZVNASA-L disodium;(5r,6s)-6-[(1r)-1-hydroxyethyl]-7-oxo-3-[(2r)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate;pentahydrate Chemical compound O.O.O.O.O.[Na+].[Na+].S([C@@H]1[C@H](C(N1C=1C([O-])=O)=O)[C@H](O)C)C=1[C@H]1CCCO1.S([C@@H]1[C@H](C(N1C=1C([O-])=O)=O)[C@H](O)C)C=1[C@H]1CCCO1 MOGICMVNWAUWMK-HIXRZVNASA-L 0.000 title 1
230000002708 enhancing effect Effects 0.000 title 1
229960000379 faropenem Drugs 0.000 title 1
210000001035 gastrointestinal tract Anatomy 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
239000004480 active ingredient Substances 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
150000002961 penems Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/429—Thiazoles condensed with heterocyclic ring systems
- A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
- A61K31/431—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems containing further heterocyclic rings, e.g. ticarcillin, azlocillin, oxacillin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Oil, Petroleum & Natural Gas (AREA)
Biophysics (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK00961049T 1999-09-17 2000-09-18 Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen DK1142573T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP26463799		1999-09-17

Publications (1)

Publication Number	Publication Date
DK1142573T3 true DK1142573T3 (da)	2006-04-10

Family

ID=17406127

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00961049T DK1142573T3 (da)	1999-09-17	2000-09-18	Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen

Country Status (11)

Country	Link
US (1)	US6531508B1 (da)
EP (1)	EP1142573B1 (da)
JP (1)	JP4745573B2 (da)
KR (1)	KR20010101030A (da)
CN (1)	CN1198611C (da)
AT (1)	ATE315395T1 (da)
CA (1)	CA2351673A1 (da)
DE (1)	DE60025503T2 (da)
DK (1)	DK1142573T3 (da)
ES (1)	ES2256035T3 (da)
WO (1)	WO2001021175A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR025976A1 (es)	1999-10-08	2002-12-26	Affinium Pharm Inc	Inhibidores de fab i.
CA2444597A1 (en) *	2001-04-06	2002-10-06	Affinium Pharmaceuticals, Inc.	Fab i inhibitors
CA2508792C (en)	2002-12-06	2013-02-05	Affinium Pharmaceuticals, Inc.	Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en)	2003-03-17	2004-09-30	Affinium Pharmaceuticals, Inc.	Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
US20050069590A1 (en) *	2003-09-30	2005-03-31	Buehler Gail K.	Stable suspensions for medicinal dosages
CA2568914C (en) *	2004-06-04	2013-09-24	Affinium Pharmaceuticals, Inc.	Therapeutic agents, and methods of making and using the same
BRPI0615265A8 (pt) *	2005-08-31	2018-03-06	Abraxis Bioscience Llc	composições compreendendo agentes farmacêuticos pouco hidrossoluíveis e agentes antimicrobianos
EP1973902A2 (en) *	2005-12-05	2008-10-01	Affinium Pharmaceuticals, Inc.	3-heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
EP2687533B1 (en)	2006-07-20	2017-07-19	Debiopharm International SA	Acrylamide derivatives as FAB I inhibitors
US20090275746A1 (en) *	2006-07-28	2009-11-05	Hetero Drugs Limited	Solid faropenem free acid
CN101129381B (zh) *	2006-08-25	2012-02-01	天津和美生物技术有限公司	含β-内酰胺类抗生素和离子螯合剂的抗生素复方
US8263613B2 (en) *	2007-02-16	2012-09-11	Affinium Pharmaceuticals, Inc.	Salts, prodrugs and polymorphs of fab I inhibitors
US9169477B2 (en)	2012-01-27	2015-10-27	Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center	Compositions and methods for immunization against bacteria expressing a carbapenemase
SMT201900411T1 (it)	2012-06-19	2019-09-09	Debiopharm Int Sa	Derivati di profaramci di (e)-n-metil-n-((3-metilbenzofuran-2-il)metil -3-(7-osso-5,6,7,8-tetraidro-1,8-naftiridin-3-il)acrilammide
BR122023021456A2 (pt)	2016-02-26	2024-02-20	Debiopharm International S.A.	Uso de di-hidrogeno fosfato de {6- [(e)-3-{metil[(3-metil-1-benfofuran-2- iol)metil]amino)-3- oxopro-1-en-1-il]-2-oxo-3,4-di-hidro-1,8-naftiridin-1(2h)- il}metila para tratamento de osteomielite do pé diabético e composição farmacêutica
FI3923914T3 (fi)	2019-02-14	2023-04-27	Debiopharm Int Sa	Afabisiiniformulaatio, menetelmä sen valmistamiseksi
MA56184A (fr)	2019-06-14	2022-04-20	Debiopharm Int Sa	Afabicine pour utilisation dans le traitement d'infections bactériennes impliquant un biofilm

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DD29756A (da) *
GB909365A (en) *	1960-04-28	1962-10-31	Horner Frank W Ltd	Orally ingestible solid penicillin compositions
GB1061426A (en) *	1964-05-22	1967-03-15	Olin Mathieson	Water-soluble penicillin composition
US4504485A (en) *	1983-04-04	1985-03-12	Schering Corporation	5R,6S,8R-6-(1-Hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylic acid
JP2514249B2 (ja) *	1989-05-23	1996-07-10	帝人株式会社	安定化されたカルシトニン類医薬組成物
ATE217195T1 (de) *	1991-02-01	2002-05-15	Suntory Ltd	Verwendung von cilastatin, glutathione und n- acetyl-l-cysteine zur herstellung eines arzneimittels zur verbesserung der resorption von carbapenem oder penem antibiotika im magen-darm- trakt
JPH0769887A (ja) *	1993-07-09	1995-03-14	Takeda Chem Ind Ltd	ペネム化合物含有固形組成物、その製造法および剤
JPH0812675A (ja) *	1994-06-30	1996-01-16	Lederle Japan Ltd	２−［（４−ハロゲン置換フェニル）チオ］−カルバペネム誘導体
WO1999036098A1 (en) *	1998-01-13	1999-07-22	Suntory Limited	Antibacterial composition for topical administration containing antibiotics

2000
- 2000-09-18 DE DE60025503T patent/DE60025503T2/de not_active Expired - Fee Related
- 2000-09-18 CN CNB008022372A patent/CN1198611C/zh not_active Expired - Fee Related
- 2000-09-18 AT AT00961049T patent/ATE315395T1/de not_active IP Right Cessation
- 2000-09-18 CA CA002351673A patent/CA2351673A1/en not_active Abandoned
- 2000-09-18 WO PCT/JP2000/006346 patent/WO2001021175A1/ja not_active Ceased
- 2000-09-18 KR KR1020017006262A patent/KR20010101030A/ko not_active Abandoned
- 2000-09-18 US US09/856,094 patent/US6531508B1/en not_active Expired - Fee Related
- 2000-09-18 DK DK00961049T patent/DK1142573T3/da active
- 2000-09-18 JP JP2001524601A patent/JP4745573B2/ja not_active Expired - Lifetime
- 2000-09-18 ES ES00961049T patent/ES2256035T3/es not_active Expired - Lifetime
- 2000-09-18 EP EP00961049A patent/EP1142573B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1142573A1 (en)	2001-10-10
WO2001021175A1 (fr)	2001-03-29
US6531508B1 (en)	2003-03-11
DE60025503D1 (de)	2006-04-06
KR20010101030A (ko)	2001-11-14
ES2256035T3 (es)	2006-07-16
EP1142573B1 (en)	2006-01-11
CN1198611C (zh)	2005-04-27
DE60025503T2 (de)	2006-09-07
CN1327385A (zh)	2001-12-19
ATE315395T1 (de)	2006-02-15
JP4745573B2 (ja)	2011-08-10
CA2351673A1 (en)	2001-03-29
EP1142573A4 (en)	2002-07-24

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EE200200486A (et)	2004-02-16	Farmatseutilised kompositsioonid, mis sisaldavad 3-aminoasetidiini derivaate, uued derivaadid ja nende valmistamismeetodid
IL162118A0 (en)	2005-11-20	Pharmaceutical compositions containing an orally active taxane derivative
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SE0102315D0 (sv)	2001-06-28	Compounds
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ATE315395T1 (de)	2006-02-15	Pharmazeutische zusammensetzungen, die faropenem natrium und eine diamineacetat verbindung zur verbesserung der magen-darm trakt absorption enthalten
DK1458377T3 (da)	2006-06-12	Farmaceutiske sammensætninger indeholdende tegaserod
EE200200342A (et)	2003-06-16	Asendatud 8-arüülkinoliinid, nende kasutamine, farmatseutiline kompositsioon ja prekursorühend
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WO2004091591A3 (fr)	2004-11-25	Composition nutritionnelle ou therapeutique contenant le compose oleurofeine ou l'un de ses derives
FI20031078A7 (fi)	2004-02-02	Antibioottisesti oletiivisia farmaseuttisia koostumuksia
NO20021898D0 (no)	2002-04-22	Farmasöytisk sammensetning inneholdende ciclesonid for applikasjon til mukosa
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