ATE284027T1 - Genetisches versuchssystem - Google Patents

Genetisches versuchssystem

Info

Publication number
ATE284027T1
ATE284027T1 AT00932373T AT00932373T ATE284027T1 AT E284027 T1 ATE284027 T1 AT E284027T1 AT 00932373 T AT00932373 T AT 00932373T AT 00932373 T AT00932373 T AT 00932373T AT E284027 T1 ATE284027 T1 AT E284027T1
Authority
AT
Austria
Prior art keywords
samples
reagents
glass slide
openings
slide member
Prior art date
Application number
AT00932373T
Other languages
English (en)
Inventor
Robert D Juncosa
Rene Bongard
Johannes Dapprich
Richard Scribner
Original Assignee
Orchid Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Biosciences Inc filed Critical Orchid Biosciences Inc
Application granted granted Critical
Publication of ATE284027T1 publication Critical patent/ATE284027T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50855—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0825—Test strips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT00932373T 1999-05-27 2000-05-11 Genetisches versuchssystem ATE284027T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/321,170 US6225109B1 (en) 1999-05-27 1999-05-27 Genetic analysis device
PCT/US2000/013100 WO2000073766A1 (en) 1999-05-27 2000-05-11 Genetic assay system

Publications (1)

Publication Number Publication Date
ATE284027T1 true ATE284027T1 (de) 2004-12-15

Family

ID=23249497

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00932373T ATE284027T1 (de) 1999-05-27 2000-05-11 Genetisches versuchssystem

Country Status (8)

Country Link
US (2) US6225109B1 (de)
EP (1) EP1196755B1 (de)
JP (1) JP2003501620A (de)
AT (1) ATE284027T1 (de)
AU (1) AU777018B2 (de)
CA (1) CA2374928A1 (de)
DE (1) DE60016415T2 (de)
WO (1) WO2000073766A1 (de)

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875440B2 (en) 1998-05-01 2011-01-25 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6780591B2 (en) 1998-05-01 2004-08-24 Arizona Board Of Regents Method of determining the nucleotide sequence of oligonucleotides and DNA molecules
US6270730B1 (en) 1998-06-16 2001-08-07 Northwest Engineering Inc. Multi-well rotary synthesizer
AU3508600A (en) * 1999-02-26 2000-09-14 Orchid Biosciences, Inc. Microstructures for use in biological assays and reactions
US6225109B1 (en) * 1999-05-27 2001-05-01 Orchid Biosciences, Inc. Genetic analysis device
US6818395B1 (en) 1999-06-28 2004-11-16 California Institute Of Technology Methods and apparatus for analyzing polynucleotide sequences
US7115423B1 (en) * 1999-10-22 2006-10-03 Agilent Technologies, Inc. Fluidic structures within an array package
US6982147B2 (en) * 2000-01-24 2006-01-03 Ingeneus Corporation Apparatus for assaying biopolymer binding by means of multiple measurements under varied conditions
US20030170659A1 (en) * 2000-01-24 2003-09-11 Ingeneus Corporation Electrical treatment of binding media to encourage, discourage and/or study biopolymer binding
US7001740B2 (en) * 2000-11-08 2006-02-21 Surface Logix, Inc. Methods of arraying biological materials using peelable and resealable devices
US6803205B2 (en) * 2000-11-08 2004-10-12 Surface Logix, Inc. Methods of measuring enzyme activity using peelable and resealable devices
US6967074B2 (en) * 2000-11-08 2005-11-22 Surface Logix, Inc. Methods of detecting immobilized biomolecules
US7439056B2 (en) 2000-11-08 2008-10-21 Surface Logix Inc. Peelable and resealable devices for arraying materials
US7371563B2 (en) * 2000-11-08 2008-05-13 Surface Logix, Inc. Peelable and resealable devices for biochemical assays
US7351575B2 (en) * 2000-11-08 2008-04-01 Surface Logix, Inc. Methods for processing biological materials using peelable and resealable devices
EP1343973B2 (de) 2000-11-16 2020-09-16 California Institute Of Technology Vorrichtung und verfahren zur durchführung von assays und screening mit hohem durchsatz
US7776571B2 (en) * 2000-12-12 2010-08-17 Autogenomics, Inc. Multi-substrate biochip unit
JP4797196B2 (ja) * 2001-02-14 2011-10-19 株式会社 フューエンス マイクロチップ
JP4148778B2 (ja) * 2001-03-09 2008-09-10 バイオミクロ システムズ インコーポレイティッド アレイとのミクロ流体的インターフェース機器
JP2004523243A (ja) * 2001-03-12 2004-08-05 カリフォルニア インスティチュート オブ テクノロジー 非同期性塩基伸長によってポリヌクレオチド配列を分析するための方法および装置
EP1384022A4 (de) 2001-04-06 2004-08-04 California Inst Of Techn Nukleinsäure-amplifikation verwendende mikrofluidvorrichtungen
EP1405056A1 (de) * 2001-06-15 2004-04-07 Zeptosens AG Körper für durchflussküvetten und deren verwendung
USD473318S1 (en) 2001-07-26 2003-04-15 Biocrystal, Ltd. Cell management device
CA2495021A1 (en) * 2001-08-06 2003-07-03 Vanderbilt University System and methods for measuring at least one metabolic rate of a plurality of cells
US6682702B2 (en) 2001-08-24 2004-01-27 Agilent Technologies, Inc. Apparatus and method for simultaneously conducting multiple chemical reactions
WO2003048295A1 (en) 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
JP4566509B2 (ja) * 2001-12-28 2010-10-20 株式会社エンプラス プラスチックプレート及びプラスチックプレート組立体
US6773677B2 (en) 2002-01-09 2004-08-10 Caliper Life Sciences, Inc. Slide cassette for fluidic injection
US7731909B1 (en) * 2002-01-22 2010-06-08 Grace Bio-Labs, Inc. Reaction surface array diagnostic apparatus
US7736594B1 (en) * 2002-01-22 2010-06-15 Grace Bio-Labs, Inc. Reaction surface array diagnostic apparatus
AU2003224817B2 (en) 2002-04-01 2008-11-06 Fluidigm Corporation Microfluidic particle-analysis systems
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
CA2480990A1 (en) * 2002-04-11 2003-10-23 Sequenom, Inc. Methods and devices for performing chemical reactions on a solid support
US20030235521A1 (en) * 2002-06-21 2003-12-25 Shea Laurence R. Array assay devices and methods of using the same
US7220573B2 (en) * 2002-06-21 2007-05-22 Agilent Technologies, Inc. Array assay devices and methods of using the same
US20060086309A1 (en) * 2002-06-24 2006-04-27 Fluiding Corporation Recirculating fluidic network and methods for using the same
US7442342B2 (en) * 2002-06-26 2008-10-28 Ge Healthcare Bio-Sciences Ab Biochip holder and method of collecting fluid
JP4057967B2 (ja) * 2002-07-31 2008-03-05 株式会社東芝 塩基配列自動解析装置
US7745203B2 (en) * 2002-07-31 2010-06-29 Kabushiki Kaisha Toshiba Base sequence detection apparatus and base sequence automatic analyzing apparatus
US7202398B2 (en) * 2002-08-16 2007-04-10 E. I. Du Pont De Nemours And Company Chalcone isomerase
JP2006501056A (ja) 2002-09-25 2006-01-12 カリフォルニア インスティテュート オブ テクノロジー ミクロ流体大規模集積
WO2004040001A2 (en) 2002-10-02 2004-05-13 California Institute Of Technology Microfluidic nucleic acid analysis
AU2003287568A1 (en) * 2002-11-08 2004-06-03 Irm, Llc Systems and methods of sorting samples
WO2004087323A1 (en) * 2003-03-28 2004-10-14 Mergen Ltd. Multi-array systems and methods of use thereof
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US8652774B2 (en) * 2003-04-16 2014-02-18 Affymetrix, Inc. Automated method of manufacturing polyer arrays
US20040241659A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Apparatus and method for hybridization and SPR detection
EP1628753A1 (de) * 2003-05-30 2006-03-01 Applera Corporation Apparatur und verfahren zur hybridisierung und spr detektion
WO2005003769A1 (ja) * 2003-07-04 2005-01-13 Kubota Corporation バイオチップ
US20050026299A1 (en) * 2003-07-31 2005-02-03 Arindam Bhattacharjee Chemical arrays on a common carrier
US7169560B2 (en) 2003-11-12 2007-01-30 Helicos Biosciences Corporation Short cycle methods for sequencing polynucleotides
JPWO2005052578A1 (ja) * 2003-11-28 2007-07-12 オリンパス株式会社 生体関連物質の検査装置とその反応ステージ
KR100695123B1 (ko) 2003-12-03 2007-03-14 삼성전자주식회사 Ｔｍ에 따라 기판상에 고정화된 프로브 폴리뉴클레오티드군을 2이상 포함하는 폴리뉴클레오티드 어레이 및 그를이용하는 표적 핵산 검출 방법
US20050135974A1 (en) * 2003-12-18 2005-06-23 Harvey Michael A. Device for preparing multiple assay samples using multiple array surfaces
US20050272057A1 (en) * 2004-01-23 2005-12-08 Abrahamsen Mitchell S Small segments of DNA determine animal identity and source
WO2005080605A2 (en) 2004-02-19 2005-09-01 Helicos Biosciences Corporation Methods and kits for analyzing polynucleotide sequences
US8034306B1 (en) * 2004-02-20 2011-10-11 Grace Bio-Labs, Inc. Reaction surface array diagnostic apparatus including a flexible microtitre plate
DE102004022483B4 (de) * 2004-05-07 2006-05-04 P.A.L.M. Microlaser Technologies Ag Halter für eine Aufnahmevorrichtung zum Aufnehmen von biologischen Objekten
JP4627455B2 (ja) * 2004-05-18 2011-02-09 三菱レイヨン株式会社 Ｄｎａマイクロアレイ処理装置
US7476734B2 (en) 2005-12-06 2009-01-13 Helicos Biosciences Corporation Nucleotide analogs
US7635562B2 (en) 2004-05-25 2009-12-22 Helicos Biosciences Corporation Methods and devices for nucleic acid sequence determination
US20050277122A1 (en) * 2004-06-14 2005-12-15 Fredrick Joseph P Devices and methods for contacting fluid with a chemical array
JP2006153785A (ja) * 2004-12-01 2006-06-15 Hitachi Ltd 溶液攪拌装置及び分析システム
US7220549B2 (en) 2004-12-30 2007-05-22 Helicos Biosciences Corporation Stabilizing a nucleic acid for nucleic acid sequencing
US7482120B2 (en) 2005-01-28 2009-01-27 Helicos Biosciences Corporation Methods and compositions for improving fidelity in a nucleic acid synthesis reaction
US7666593B2 (en) 2005-08-26 2010-02-23 Helicos Biosciences Corporation Single molecule sequencing of captured nucleic acids
TW200722524A (en) * 2005-12-13 2007-06-16 Zen U Biotechnology Co Ltd The device of determining the activity value of nattokinase
US7815868B1 (en) 2006-02-28 2010-10-19 Fluidigm Corporation Microfluidic reaction apparatus for high throughput screening
USD566850S1 (en) * 2006-07-18 2008-04-15 Leja Products B.V. Counting chamber—8 chamber slide for counting cells in biological samples
USD602165S1 (en) * 2007-08-10 2009-10-13 Oxoid Limited Diagnostic test strip
WO2009091535A1 (en) * 2008-01-15 2009-07-23 Empire Genomics Llc Method and device for dual array hybridization karyotype analysis
WO2009137244A1 (en) * 2008-04-15 2009-11-12 Charles River Laboratories, Inc. Cartridge and method for sample analysis
DE102008025992B4 (de) * 2008-05-30 2011-01-27 Siemens Healthcare Diagnostics Gmbh Titerplatte und Verfahren zur Detektion eines Analyten
CN101368206B (zh) * 2008-07-16 2012-08-22 深圳华因康基因科技有限公司 测序反应小室、基因测序反应台及基因测序设备
US20100227327A1 (en) * 2008-08-08 2010-09-09 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
US20100036110A1 (en) * 2008-08-08 2010-02-11 Xiaoliang Sunney Xie Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides
KR101578153B1 (ko) * 2008-08-26 2015-12-17 삼성전자주식회사 슬라이드 반응 장치
DE102008053270A1 (de) 2008-10-27 2010-05-12 Medizinische Hochschule Hannover Vorrichtung und Verfahren zur Analyse von Zellen
KR20100090955A (ko) * 2009-02-09 2010-08-18 삼성전자주식회사 혼성화 챔버 및 이를 이용한 혼성화 방법
USD672053S1 (en) * 2010-05-07 2012-12-04 Anp Technologies, Inc. Multi-lateral flow assay strip carrier assembly
TW201236760A (en) 2010-11-01 2012-09-16 Nanoink Inc High-throughput assay methods and articles
WO2012061314A1 (en) 2010-11-01 2012-05-10 Nanoink, Inc. High-throughput slide processing apparatus
CN202379991U (zh) * 2011-01-10 2012-08-15 伊鲁米那股份有限公司 核酸测序系统
US8951781B2 (en) * 2011-01-10 2015-02-10 Illumina, Inc. Systems, methods, and apparatuses to image a sample for biological or chemical analysis
US9295988B2 (en) * 2011-03-08 2016-03-29 Colorado State University Research Foundation Microfluidic cytochemical staining system
WO2013059746A1 (en) 2011-10-19 2013-04-25 Nugen Technologies, Inc. Compositions and methods for directional nucleic acid amplification and sequencing
EP2807292B1 (de) 2012-01-26 2019-05-22 Tecan Genomics, Inc. Zusammensetzungen und verfahren zur gezielten nukleinsäuresequenzanreicherung und erzeugung einer hocheffizienten bibliothek
CA2877094A1 (en) 2012-06-18 2013-12-27 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
WO2014121091A1 (en) 2013-02-01 2014-08-07 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
US9822408B2 (en) 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
US9069358B2 (en) 2013-06-24 2015-06-30 Biolytic Lab Performance, Inc. System for controlling and optimizing reactions in solid phase synthesis of small molecules
WO2015073711A1 (en) 2013-11-13 2015-05-21 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
EP3540074A1 (de) 2013-12-11 2019-09-18 The Regents of the University of California Verfahren zur markierung innerer regionen von nukleinsäuremolekülen
US9745614B2 (en) 2014-02-28 2017-08-29 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
US10526641B2 (en) 2014-08-01 2020-01-07 Dovetail Genomics, Llc Tagging nucleic acids for sequence assembly
CA2957633A1 (en) 2014-08-06 2016-02-11 Nugen Technologies, Inc. Digital measurements from targeted sequencing
WO2016134034A1 (en) 2015-02-17 2016-08-25 Dovetail Genomics Llc Nucleic acid sequence assembly
US11807896B2 (en) 2015-03-26 2023-11-07 Dovetail Genomics, Llc Physical linkage preservation in DNA storage
US10384207B2 (en) 2015-07-21 2019-08-20 Neuro Probe Incorporated Assay apparatus and methods
CA3002740A1 (en) 2015-10-19 2017-04-27 Dovetail Genomics, Llc Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection
SG11201807117WA (en) 2016-02-23 2018-09-27 Dovetail Genomics Llc Generation of phased read-sets for genome assembly and haplotype phasing
KR102412442B1 (ko) 2016-05-13 2022-06-22 더브테일 제노믹스 엘엘씨 보존된 샘플로부터의 장범위 링키지 정보의 회수
US11083907B2 (en) 2016-08-01 2021-08-10 Neuropair, Inc. Superparamagnetic particle scaffold for regenerating damaged neural tissue
US10190155B2 (en) 2016-10-14 2019-01-29 Nugen Technologies, Inc. Molecular tag attachment and transfer
CN110612160B (zh) * 2017-03-31 2022-06-03 前进生物技术股份有限公司 用于测量流体体积的装置
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
EP3746566A1 (de) 2018-01-31 2020-12-09 Dovetail Genomics, LLC Probenvorbereitung zur wiederherstellung der dna-verknüpfung
US10704094B1 (en) 2018-11-14 2020-07-07 Element Biosciences, Inc. Multipart reagents having increased avidity for polymerase binding
AU2019392932B2 (en) 2018-12-07 2023-11-02 Element Biosciences, Inc. Flow cell device and use thereof
WO2020154248A1 (en) 2019-01-21 2020-07-30 Forward Biotech, Inc. Liquid evaluation
US11633741B2 (en) * 2019-03-19 2023-04-25 Miltenyi Biotec B.V. & Co. KG Slide chamber
US12313627B2 (en) 2019-05-01 2025-05-27 Element Biosciences, Inc. Multivalent binding composition for nucleic acid analysis
EP4545965A3 (de) 2019-06-27 2025-06-11 Dovetail Genomics, LLC Verfahren und zusammensetzungen für näherungsligation
US11060138B1 (en) 2020-01-17 2021-07-13 Element Biosciences, Inc. Nucleic acid sequencing systems
EP3851542A1 (de) 2020-01-20 2021-07-21 Tecan Genomics, Inc. Verarmung von reichlich uninformativen sequenzen
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system
US11198121B1 (en) 2020-06-10 2021-12-14 Element Biosciences, Inc. Flow cell systems and devices
EP4244035A4 (de) * 2020-11-11 2025-01-08 University of Cincinnati Verfahren zur kovalenten bindung von kohlenstoffnanoröhren an substrate
EP4263784A1 (de) * 2020-12-15 2023-10-25 Colgate-Palmolive Company Mikrofluidische vorrichtung zum testen von biomaterialien enthaltenden wässrigen proben
AU2022316142A1 (en) 2021-07-21 2024-02-22 Element Biosciences, Inc. Optical systems for nucleic acid sequencing and methods thereof
GB2628932A (en) 2021-12-09 2024-10-09 Forward Biotech Inc Liquid evaluation device

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
US6176962B1 (en) * 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
CA2124087C (en) * 1991-11-22 2002-10-01 James L. Winkler Combinatorial strategies for polymer synthesis
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
JP2763468B2 (ja) * 1992-12-25 1998-06-11 株式会社日立製作所 光散乱を用いた液体内の粒子分類装置
DE69527585T2 (de) * 1994-06-08 2003-04-03 Affymetrix, Inc. Verfahren und Vorrichtung zum Verpacken von Chips
US5807522A (en) * 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
US5763263A (en) * 1995-11-27 1998-06-09 Dehlinger; Peter J. Method and apparatus for producing position addressable combinatorial libraries
JP3748571B2 (ja) * 1996-11-18 2006-02-22 ノバルティス アクチエンゲゼルシャフト 測定装置及びその使用方法
US5922604A (en) * 1997-06-05 1999-07-13 Gene Tec Corporation Thin reaction chambers for containing and handling liquid microvolumes
US6322683B1 (en) * 1999-04-14 2001-11-27 Caliper Technologies Corp. Alignment of multicomponent microfabricated structures
US6225109B1 (en) * 1999-05-27 2001-05-01 Orchid Biosciences, Inc. Genetic analysis device
DE10014204C2 (de) * 2000-03-22 2002-08-14 Max Planck Gesellschaft Mikrohybridisierungskammer

Also Published As

Publication number Publication date
AU777018B2 (en) 2004-09-30
US6720143B2 (en) 2004-04-13
US20010051113A1 (en) 2001-12-13
AU5010400A (en) 2000-12-18
EP1196755B1 (de) 2004-12-01
EP1196755A4 (de) 2002-08-14
DE60016415D1 (de) 2005-01-05
US6225109B1 (en) 2001-05-01
EP1196755A1 (de) 2002-04-17
JP2003501620A (ja) 2003-01-14
CA2374928A1 (en) 2000-12-07
DE60016415T2 (de) 2005-05-19
WO2000073766A1 (en) 2000-12-07

Similar Documents

Publication Publication Date Title
ATE284027T1 (de) Genetisches versuchssystem
WO2002035260A3 (en) Light detection device
WO2003100012A3 (en) Microarrays and method for running hybridization reaction for multiple samples on a single microarray
ATE336591T1 (de) Nachweisverfahren für kurze sequenzvarianten
DE60042262D1 (en) Biochip
KR930010192A (ko) 에이치엘에이(hla) 제i형 디엠에이(dna) 타이핑 방법 및 시약
DK0804731T3 (da) Fremgangsmåde og apparat til fremstilling af microarrays af biologiske prøver
ATE416375T1 (de) Mikrofluidische analysesysteme und -verfahren mit extrem hohem durchsatz
WO2004099378A3 (en) Automated laboratory for high-throughput biological assays and rna interference
DE69738941D1 (de) Hochdurchsatz-screening-testsystem mittels mikrofluidischer vorrichtungen
CA2258489A1 (en) High-throughput screening assay systems in microscale fluidic devices
WO2000050872A3 (en) A system for cell-based screening
CA2348132A1 (en) A system for cell-based screening
EP1188482A3 (de) Vorrichtung und Verfahren zur Durchführung von Versuchen
EP1391242A3 (de) Mikrosäulenbasierte Anordnung zur Hochdurchsatzanalyse
WO2000017643A8 (en) A system for cell-based screening
EP0848067A3 (de) Computerunterstützte Verfahren zur Analysieren von biologischen Sequenzen
EP1350851A4 (de) Verfahren zum nachweis von polymorphismus in dna unter verwendung der massenspektroskopie
WO2008028160A3 (en) Substrates, systems and methods for analyzing materials
NZ504112A (en) Continuous format high throughput screening for testing compound for biological activity
WO2003057873A1 (en) Plastic plate and plastic plate assembly
HUP0003261A2 (hu) Több funkció- vagy mátrixelemen belül, továbbá ezek alkalmazásai
DE69917636D1 (en) Polymerasesignalversuch
WO2001026029A3 (en) Method and system for providing genotype clinical information over a computer network
WO2002024959A3 (en) Multiple reporter read-out for bioassays

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1196755

Country of ref document: EP

REN Ceased due to non-payment of the annual fee