ATE284139T1 - Mikroinjektion von kälteschutzmitteln zur konservierung von zellen - Google Patents

Mikroinjektion von kälteschutzmitteln zur konservierung von zellen

Info

Publication number: ATE284139T1
Authority: AT; Austria
Prior art keywords: refrigerants; microinjection; biological material; preserve cells; storage
Prior art date: 2000-05-16

Application number

AT01935562T

Other languages

English (en)

Inventor

Mehmet Toner

Ali Eroglu

Thomas Toth

Original Assignee

Gen Hospital Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-16

Filing date

2001-05-16

Publication date

2004-12-15

2001-05-16 Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp

2004-12-15 Application granted granted Critical

2004-12-15 Publication of ATE284139T1 publication Critical patent/ATE284139T1/de

Links

238000000520 microinjection Methods 0.000 title 1
239000003507 refrigerant Substances 0.000 title 1
239000012620 biological material Substances 0.000 abstract 3
210000000170 cell membrane Anatomy 0.000 abstract 2
235000000346 sugar Nutrition 0.000 abstract 2
HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
-1 Carbohydrate sugars Chemical class 0.000 abstract 1
229920002307 Dextran Polymers 0.000 abstract 1
239000005715 Fructose Substances 0.000 abstract 1
229930091371 Fructose Natural products 0.000 abstract 1
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 abstract 1
MUPFEKGTMRGPLJ-RMMQSMQOSA-N Raffinose Natural products O(C[C@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O[C@@]2(CO)[C@H](O)[C@@H](O)[C@@H](CO)O2)O1)[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 MUPFEKGTMRGPLJ-RMMQSMQOSA-N 0.000 abstract 1
229930006000 Sucrose Natural products 0.000 abstract 1
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
MUPFEKGTMRGPLJ-UHFFFAOYSA-N UNPD196149 Natural products OC1C(O)C(CO)OC1(CO)OC1C(O)C(O)C(O)C(COC2C(C(O)C(O)C(CO)O2)O)O1 MUPFEKGTMRGPLJ-UHFFFAOYSA-N 0.000 abstract 1
HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
230000000513 bioprotective effect Effects 0.000 abstract 1
235000014633 carbohydrates Nutrition 0.000 abstract 1
210000004027 cell Anatomy 0.000 abstract 1
FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
238000004321 preservation Methods 0.000 abstract 1
239000003223 protective agent Substances 0.000 abstract 1
MUPFEKGTMRGPLJ-ZQSKZDJDSA-N raffinose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)O)O1 MUPFEKGTMRGPLJ-ZQSKZDJDSA-N 0.000 abstract 1
239000005720 sucrose Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/125—Freeze protecting agents, e.g. cryoprotectants or osmolarity regulators
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Dentistry (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Investigating Or Analysing Materials By Optical Means (AREA)
Nuclear Medicine (AREA)
Spectrometry And Color Measurement (AREA)

AT01935562T 2000-05-16 2001-05-16 Mikroinjektion von kälteschutzmitteln zur konservierung von zellen ATE284139T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US20487700P	2000-05-16	2000-05-16
US09/798,327 US20020045156A1 (en)	2000-05-16	2001-03-02	Microinjection of cryoprotectants for preservation of cells
PCT/US2001/015748 WO2001087062A2 (en)	2000-05-16	2001-05-16	Microinjection of cryoprotectants for preservation of cells

Publications (1)

Publication Number	Publication Date
ATE284139T1 true ATE284139T1 (de)	2004-12-15

Family

ID=26899865

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01935562T ATE284139T1 (de)	2000-05-16	2001-05-16	Mikroinjektion von kälteschutzmitteln zur konservierung von zellen

Country Status (12)

Country	Link
US (2)	US20020045156A1 (de)
EP (1)	EP1283670B1 (de)
JP (1)	JP2003533192A (de)
AT (1)	ATE284139T1 (de)
AU (2)	AU6164401A (de)
CA (1)	CA2409102A1 (de)
DE (1)	DE60107672T2 (de)
ES (1)	ES2232624T3 (de)
IL (2)	IL152745A0 (de)
MX (1)	MXPA02011362A (de)
PT (1)	PT1283670E (de)
WO (1)	WO2001087062A2 (de)

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EP1711053A2 (de)	2004-02-02	2006-10-18	I.M.T. Interface Multigrad Technology Ltd.	Biologisches material sowie verfahren und lösungen für seine konservierung
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US7892726B2 (en)	2004-06-07	2011-02-22	Core Dynamics Limited	Method for sterilizing lyophilized eukaryotic anuclear cells with gamma irradiation
US8037696B2 (en)	2004-08-12	2011-10-18	Core Dynamics Limited	Method and apparatus for freezing or thawing of a biological material
CA2595638A1 (en) *	2005-01-28	2006-08-03	Canadian Blood Services	A method of cryopreserving cells and tissues by liposomal delivery of sugars to enhance post-thaw viability
US7622240B2 (en) *	2005-02-28	2009-11-24	International Business Machines Corporation	Low blur molecular resist
US8198085B2 (en)	2005-08-03	2012-06-12	Core Dynamics Limited	Somatic cells for use in cell therapy
WO2007120829A2 (en) *	2006-04-14	2007-10-25	The General Hospital Corporation	Methods for the cryopreservation of mammalian cells
US20080113432A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for reanimating cryopreserved oocytes
US20080113431A1 (en) *	2006-11-15	2008-05-15	Mariposa Biotechnology, Inc.	Methods and compositions for cryopreserving oocytes
CA2741754A1 (en) *	2008-08-29	2010-03-04	The Curators Of The University Of Missouri	High-throughput and non-invasive method to vitrify porcine embryos
US20100311036A1 (en) *	2009-06-09	2010-12-09	University Of South Carolina	Methods for Augmentation of Cell Cryopreservation
US20120270293A1 (en) *	2009-12-07	2012-10-25	Wei-Sing Chu	Standardization of tissue specimen preservation by ultrasound and temperature control
ITMI20110678A1 (it) *	2011-04-20	2012-10-21	Consiglio Nazionale Ricerche	Composizione e metodo per la crioconservazione di cellule
US20130008191A1 (en) *	2011-07-07	2013-01-10	Suchak Naresh J	Methods for freezing and thawing proteins
WO2014085801A1 (en)	2012-11-30	2014-06-05	The Broad Institute, Inc.	Cryo-treatment in a microfluidic device
US10918102B2 (en)	2014-03-13	2021-02-16	The General Hospital Corporation	Devices and methods to improve and assess viability of human livers
US10448631B2 (en)	2015-09-22	2019-10-22	East Carolina University	Cryopreservation using sucralose
JP7486286B2 (ja) *	2016-06-29	2024-05-17	ザジェネラルホスピタルコーポレイション	生物学的物質の凍結保存および安定化のための氷核形成調合物
WO2018017843A1 (en) *	2016-07-22	2018-01-25	Tissue Testing Technologies Llc	Enhancement of cell cryopreservation with glycolipids
US10815456B2 (en)	2016-10-04	2020-10-27	Transwell Biotech Co., Ltd.	Composition, kit and method for cryopreserving cells
JP6873456B2 (ja) *	2016-10-26	2021-05-19	ヨダカ技研株式会社	細胞搬送システム
PL3534852T3 (pl)	2016-11-02	2022-05-09	Miraki Innovation Think Tank Llc	Urządzenia do wytwarzania zawiesin
US11324673B2 (en)	2016-11-18	2022-05-10	Miraki Innovation Think Tank Llc	Cosmetic appearance of skin
US11439532B2 (en)	2017-04-05	2022-09-13	Miraki Innovation Think Tank Llc	Point of delivery cold slurry generation
MX2019011996A (es)	2017-04-05	2020-01-20	Miraki Innovation Think Tank Llc	Contención de suspensión fría.
EP3638019A4 (de)	2017-06-14	2020-08-26	The General Hospital Corporation	Kryokonservierung mit temperaturen weit unter dem nullpunkt
US10500342B2 (en)	2017-08-21	2019-12-10	Miraki Innovation Think Tank Llc	Cold slurry syringe
US12472475B2 (en)	2018-02-02	2025-11-18	The General Hospital Corporation	Methods of supercooling aqueous samples
US12167729B2 (en)	2018-05-30	2024-12-17	The General Hospital Corporation	Cryopreservation of tissues and organs
KR20210045443A (ko) *	2018-09-28	2021-04-26	가부시기가이샤오오쓰까세이야꾸고오죠오	아카보즈 또는 스타키오스를 포함하는 포유동물 세포 보존용 액
CN109566597A (zh) *	2018-11-05	2019-04-05	北京世纪劲得生物技术有限公司	一种宫内膜干细胞保护液及其制备方法
WO2020242970A1 (en) *	2019-05-24	2020-12-03	East Carolina University	Preservation using sugars
US12453805B2 (en)	2020-09-24	2025-10-28	Everest Medical Innovation GmbH	Cryoprotective compositions, surgical kits, and methods for protection of a surgical site during cryosurgery
US12426594B2 (en)	2020-09-24	2025-09-30	Everest Medical Innovation GmbH	Cryoprotective compositions and methods for protection of a surgical site during cryosurgery
CN113925049B (zh) *	2021-12-17	2022-04-29	广东乾晖生物科技有限公司	一种保持细胞活性的细胞保存液及其制备方法和应用

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2001
- 2001-03-02 US US09/798,327 patent/US20020045156A1/en not_active Abandoned
- 2001-05-16 PT PT01935562T patent/PT1283670E/pt unknown
- 2001-05-16 US US09/859,105 patent/US6673607B2/en not_active Expired - Lifetime
- 2001-05-16 JP JP2001583540A patent/JP2003533192A/ja not_active Withdrawn
- 2001-05-16 ES ES01935562T patent/ES2232624T3/es not_active Expired - Lifetime
- 2001-05-16 WO PCT/US2001/015748 patent/WO2001087062A2/en not_active Ceased
- 2001-05-16 IL IL15274501A patent/IL152745A0/xx active IP Right Grant
- 2001-05-16 AT AT01935562T patent/ATE284139T1/de not_active IP Right Cessation
- 2001-05-16 CA CA002409102A patent/CA2409102A1/en not_active Abandoned
- 2001-05-16 EP EP01935562A patent/EP1283670B1/de not_active Expired - Lifetime
- 2001-05-16 MX MXPA02011362A patent/MXPA02011362A/es active IP Right Grant
- 2001-05-16 AU AU6164401A patent/AU6164401A/xx active Pending
- 2001-05-16 DE DE60107672T patent/DE60107672T2/de not_active Expired - Fee Related
- 2001-05-16 AU AU2001261644A patent/AU2001261644B2/en not_active Ceased
2002
- 2002-11-11 IL IL152745A patent/IL152745A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES2232624T3 (es)	2005-06-01
DE60107672D1 (de)	2005-01-13
US20020098470A1 (en)	2002-07-25
US6673607B2 (en)	2004-01-06
WO2001087062A3 (en)	2002-03-28
EP1283670A4 (de)	2003-09-17
DE60107672T2 (de)	2005-12-15
EP1283670A2 (de)	2003-02-19
AU2001261644B2 (en)	2006-04-13
MXPA02011362A (es)	2004-08-12
IL152745A (en)	2007-10-31
PT1283670E (pt)	2005-03-31
CA2409102A1 (en)	2001-11-22
US20020045156A1 (en)	2002-04-18
HK1052835A1 (en)	2003-10-03
JP2003533192A (ja)	2003-11-11
EP1283670B1 (de)	2004-12-08
IL152745A0 (en)	2003-06-24
AU6164401A (en)	2001-11-26
WO2001087062A2 (en)	2001-11-22

Legal Events

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2005-09-15

UEP

Publication of translation of european patent specification

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2010-02-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE284139T1 (de)	2004-12-15	Mikroinjektion von kälteschutzmitteln zur konservierung von zellen
WO2000001231A3 (en)	2000-06-22	Improved methods for storing neural cells
ATE330467T1 (de)	2006-07-15	Lagerung von zellen, gewebe und organen in medien auf gel-basis
Bruinsma et al.	2017	Subzero organ preservation: the dawn of a new ice age?
ATE103137T1 (de)	1994-04-15	Biologische kryoprotektion.
WO2007031871A3 (en)	2007-07-19	Support device for cells culture
WO2006121755A3 (en)	2007-06-21	Utilization of fructose in microbial production strains
WO2003083070A3 (en)	2004-02-26	Endothelial cells derived from human embryonic stem cells
DK2316933T3 (da)	2020-08-31	Systemer til sædcellekonservering og -behandling
MX166186B (es)	1992-12-23	Metodo para crioperservar valvulas cardiacas
CN111011363A (zh)	2020-04-17	间充质干细胞冻存液、冻存方法、保存试剂盒和复苏方法
WO2005099758A3 (en)	2006-10-26	Injectable bioartificial tissue matrix
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Schwalb et al.	1998	New solution for prolonged myocardial preservation for transplantation.
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Jin et al.	2012	Equilibrium vitrification of mouse embryos at various developmental stages
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AU2001288229A1 (en)	2002-02-13	An advantageous carrier solution for vitrifiable concentrations of cryoprotectants, and compatible cryoprotectant mixtures
WO2002050842A3 (de)	2002-12-27	Verfahren zum auslesen und speichern eines zustandes aus einem oder in einen ferroelektrischen transistor einer speicherzelle und speichermatrix
WO2001070020A3 (en)	2002-03-21	Method and solutions for cryopreservingoocytes
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Campbell et al.	2004	Long Term Exposure to Disaccharides Produces Viable Cells After Preservation
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