ATE284401T1 - Verknüpfte polycyclische heterocyclische verbindungen - Google Patents

Verknüpfte polycyclische heterocyclische verbindungen

Info

Publication number: ATE284401T1
Authority: AT; Austria
Prior art keywords: ring; optionally substituted; rings; optionally; aromatic ring
Prior art date: 1995-05-31

Application number

AT96920027T

Other languages

English (en)

Inventor

Hiroyuki Sugumi

Jun Niijima

Yoshihiko Kotake

Toshimi Okada

Jun-Ichi Kamata

Kentaro Yoshimatsu

Takeshi Nagasu

Katsuji Nakamura

Toshimitsu Uenaka

Atsumi Yamaguchi

Hiroshi Yoshino

Nozomu Koyanagi

Kyosuke Kito

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-31

Filing date

1996-05-31

Publication date

2004-12-15

1996-05-31 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

1996-05-31 Priority claimed from PCT/JP1996/001487 external-priority patent/WO1996038446A1/ja

2004-12-15 Application granted granted Critical

2004-12-15 Publication of ATE284401T1 publication Critical patent/ATE284401T1/de

Links

150000002391 heterocyclic compounds Chemical class 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 4
125000002950 monocyclic group Chemical group 0.000 abstract 3
230000000259 anti-tumor effect Effects 0.000 abstract 2
125000002619 bicyclic group Chemical group 0.000 abstract 2
KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 1
GCNTZFIIOFTKIY-UHFFFAOYSA-N 4-hydroxypyridine Chemical group OC1=CC=NC=C1 GCNTZFIIOFTKIY-UHFFFAOYSA-N 0.000 abstract 1
UOSQFVCDJBZRKS-UHFFFAOYSA-N 4h-1,4-oxazine Chemical group N1C=COC=C1 UOSQFVCDJBZRKS-UHFFFAOYSA-N 0.000 abstract 1
ZOXMLSDKXHNVOQ-UHFFFAOYSA-N 4h-1,4-thiazine Chemical group N1C=CSC=C1 ZOXMLSDKXHNVOQ-UHFFFAOYSA-N 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
-1 amidino, guanidino Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000004585 polycyclic heterocycle group Chemical group 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000000168 pyrrolyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/16—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/06—Peri-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT96920027T 1995-05-31 1996-05-31 Verknüpfte polycyclische heterocyclische verbindungen ATE284401T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP13399295		1995-05-31
JP30919595		1995-11-28
PCT/JP1996/001487 WO1996038446A1 (en)	1995-05-31	1996-05-31	Fused polycyclic heterocycle derivatives

Publications (1)

Publication Number	Publication Date
ATE284401T1 true ATE284401T1 (de)	2004-12-15

Family

ID=26468199

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96920027T ATE284401T1 (de)	1995-05-31	1996-05-31	Verknüpfte polycyclische heterocyclische verbindungen

Country Status (12)

Country	Link
US (1)	US5952335A (de)
EP (1)	EP0831094B1 (de)
KR (1)	KR100399704B1 (de)
CN (1)	CN1067686C (de)
AT (1)	ATE284401T1 (de)
AU (1)	AU703111B2 (de)
DE (1)	DE69634004T2 (de)
ES (1)	ES2229272T3 (de)
HU (1)	HUP9802672A3 (de)
MX (1)	MX9709254A (de)
NO (1)	NO310149B1 (de)
NZ (1)	NZ308657A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10164564B4 (de) *	2001-12-14	2007-05-16	Zentaris Gmbh	Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)
WO2004063156A1 (en) *	2003-01-08	2004-07-29	Biovitrum Ab	Novel indole derivates as fabp-4 inhibitors
EP1765341A4 (de) *	2004-06-04	2010-04-14	Chemgenex Pharmaceuticals Inc	Verfahren zur behandlung proliferativer zellkrankheit unter verwendung von naphthalimid und parp-1-inhibitoren
US20120283282A1 (en) *	2009-06-18	2012-11-08	Arleen Rifkind	Photoproducts of Tryptophan, Their Synthesis and Uses Thereof
CN104098506A (zh) *	2014-07-15	2014-10-15	华东理工大学	一类苯并[c]咔唑酰胺化合物的制备方法及用途
CN107141295A (zh) *	2017-05-27	2017-09-08	重庆文理学院	一种尿嘧啶类衍生物的简易合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3962438A (en) *	1975-01-07	1976-06-08	Smithkline Corporation	Anti-arthritic 1H-pyrimido-(5,4,3-kl)phenothiazine-1,3(2H)-diones and 1-thiones
ATE162526T1 (de) *	1990-06-26	1998-02-15	Res Corp Technologies Inc	1,2-dihydro-3h-dibenzoisochinolin-1,3-dione als antitumormittel

1996
- 1996-05-31 ES ES96920027T patent/ES2229272T3/es not_active Expired - Lifetime
- 1996-05-31 DE DE69634004T patent/DE69634004T2/de not_active Expired - Lifetime
- 1996-05-31 KR KR1019970708665A patent/KR100399704B1/ko not_active Expired - Fee Related
- 1996-05-31 AU AU58454/96A patent/AU703111B2/en not_active Ceased
- 1996-05-31 CN CN96194291A patent/CN1067686C/zh not_active Expired - Fee Related
- 1996-05-31 MX MX9709254A patent/MX9709254A/es not_active IP Right Cessation
- 1996-05-31 EP EP96920027A patent/EP0831094B1/de not_active Expired - Lifetime
- 1996-05-31 HU HU9802672A patent/HUP9802672A3/hu unknown
- 1996-05-31 US US08/952,778 patent/US5952335A/en not_active Expired - Lifetime
- 1996-05-31 AT AT96920027T patent/ATE284401T1/de not_active IP Right Cessation
- 1996-05-31 NZ NZ308657A patent/NZ308657A/en not_active IP Right Cessation
1997
- 1997-11-28 NO NO19975493A patent/NO310149B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR19990022186A (ko)	1999-03-25
EP0831094A1 (de)	1998-03-25
EP0831094B1 (de)	2004-12-08
KR100399704B1 (ko)	2003-12-18
MX9709254A (es)	1998-03-31
HUP9802672A3 (en)	2000-04-28
ES2229272T3 (es)	2005-04-16
AU5845496A (en)	1996-12-18
CN1185781A (zh)	1998-06-24
NO975493D0 (no)	1997-11-28
EP0831094A4 (de)	2001-11-21
DE69634004T2 (de)	2005-11-10
US5952335A (en)	1999-09-14
AU703111B2 (en)	1999-03-18
HUP9802672A2 (hu)	1999-04-28
NO975493L (no)	1998-01-29
NZ308657A (en)	1999-10-28
DE69634004D1 (de)	2005-01-13
NO310149B1 (no)	2001-05-28
CN1067686C (zh)	2001-06-27

Legal Events

Date	Code	Title	Description
2005-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69034202D1 (de)	2005-09-22	Zwischenprodukte zur Herstellung von non-peptiden retroviralproteasehemmenden Verbindungen
FI941417A0 (fi)	1994-03-25	Typpipitoiset heterosykliset yhdisteet
PT673937E (pt)	2004-04-30	Derivados biciclicos heterociclicos de sulfonamida e de ester sulfonico
ATE68172T1 (de)	1991-10-15	Naphthalenderivate, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen.
AU652981B2 (en)	1994-09-15	Condensed benzoxa ring compound, production thereof, and pharmaceutical composition containing the same
ATE203236T1 (de)	2001-08-15	Neue kondensierte indan-derivate und ihre pharmazeutisch verträglichen salze
FI931011A0 (fi)	1993-03-08	Kondenserade heterocykliska ketonderivat, deras framstaellning och anvaendning
NO892295D0 (no)	1989-06-05	Fremgangsmaate for fremstilling av nye cefemforbindelser.
PT87277A (pt)	1988-05-01	Process for the preparation of new bicyclic compounds and pharmaceutical compositions comprising same
ES2056860T3 (es)	1994-10-16	Derivados de n-((2-oxopirrolidin-1-il)-acetil)piperazina y medicamento contra la demencia senil.
ATE284401T1 (de)	2004-12-15	Verknüpfte polycyclische heterocyclische verbindungen
CA2220509A1 (en)	1996-12-05	Fused polycyclic heterocycle derivatives
ATE194982T1 (de)	2000-08-15	Benzoxazepin-derivate als cholinesterase- inhibitoren
KR950704333A (ko)	1995-11-17	신규한 세펨 유도체(novel cephem derivatives)