PT673937E - Derivados biciclicos heterociclicos de sulfonamida e de ester sulfonico - Google Patents
Derivados biciclicos heterociclicos de sulfonamida e de ester sulfonicoInfo
- Publication number
- PT673937E PT673937E PT94926372T PT94926372T PT673937E PT 673937 E PT673937 E PT 673937E PT 94926372 T PT94926372 T PT 94926372T PT 94926372 T PT94926372 T PT 94926372T PT 673937 E PT673937 E PT 673937E
- Authority
- PT
- Portugal
- Prior art keywords
- ring
- nitrogen
- optionally substituted
- sulfonamide
- sulfononic
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 229940124530 sulfonamide Drugs 0.000 title abstract 2
- 150000003456 sulfonamides Chemical class 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- -1 bicyclic heterocyclic sulfonamide Chemical class 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24861493 | 1993-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT673937E true PT673937E (pt) | 2004-04-30 |
Family
ID=17180741
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT94926372T PT673937E (pt) | 1993-09-10 | 1994-09-08 | Derivados biciclicos heterociclicos de sulfonamida e de ester sulfonico |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5767283A (pt) |
| EP (1) | EP0673937B1 (pt) |
| KR (2) | KR0174752B1 (pt) |
| CN (2) | CN1221533C (pt) |
| AT (1) | ATE255106T1 (pt) |
| AU (2) | AU683492B2 (pt) |
| CA (1) | CA2146961C (pt) |
| DE (1) | DE69433353T2 (pt) |
| DK (1) | DK0673937T3 (pt) |
| ES (1) | ES2206469T3 (pt) |
| HU (1) | HU224069B1 (pt) |
| NO (1) | NO303778B1 (pt) |
| NZ (1) | NZ273073A (pt) |
| PT (1) | PT673937E (pt) |
| RU (2) | RU2128648C1 (pt) |
| WO (1) | WO1995007276A1 (pt) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995000509A1 (en) * | 1993-06-25 | 1995-01-05 | Kumiai Chemical Industry Co., Ltd. | Indazolesulfonylurea derivative, use thereof, and intermediate for production thereof |
| AU5348396A (en) * | 1995-05-01 | 1996-11-21 | Fujisawa Pharmaceutical Co., Ltd. | Imidazo 1,2-a pyridine and imidazo 1,2-a pyridezine derivati ves and their use as bone resorption inhibitors |
| JP4130700B2 (ja) * | 1996-02-26 | 2008-08-06 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗腫瘍剤含有組成物 |
| WO1998016227A1 (en) * | 1996-10-15 | 1998-04-23 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia |
| JP2000247949A (ja) * | 1999-02-26 | 2000-09-12 | Eisai Co Ltd | スルホンアミド含有インドール化合物 |
| JP4516942B2 (ja) * | 1999-02-26 | 2010-08-04 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド含有インドール化合物 |
| US6653309B1 (en) | 1999-04-26 | 2003-11-25 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme technical field of the invention |
| US6521658B1 (en) | 1999-05-28 | 2003-02-18 | Abbott Laboratories | Cell proliferation inhibitors |
| MXPA02006474A (es) * | 1999-12-28 | 2002-11-29 | Eisai Co Ltd | Compuestos heterociclicos que contienen sulfonamida. |
| KR100767002B1 (ko) * | 2000-02-03 | 2007-10-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 인테그린 발현 저해제 |
| KR100767000B1 (ko) * | 2000-02-03 | 2007-10-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 인테그린 발현 저해제 |
| TWI283575B (en) * | 2000-10-31 | 2007-07-11 | Eisai Co Ltd | Medicinal compositions for concomitant use as anticancer agent |
| US7445892B2 (en) | 2000-11-24 | 2008-11-04 | Eisai Co., Ltd. | Method of testing anticancer agent-sensitivity of tumor cells |
| WO2002066073A1 (en) * | 2001-02-21 | 2002-08-29 | Eisai C0. Ltd. | Method of examining effect of angionegesis inhibitor mediated by the inhibition of integrin expression |
| WO2002070478A1 (en) * | 2001-03-06 | 2002-09-12 | Astrazeneca Ab | Indolone derivatives having vascular-damaging activity |
| TW589181B (en) * | 2001-09-05 | 2004-06-01 | Eisai Co Ltd | Lymphocytic activation inhibitor and remedial agent for autoimmune disease |
| DE60317529T2 (de) * | 2002-09-19 | 2008-09-25 | Schering Corp. | Imidazopyridine als hemmstoffe cyclin abhängiger kinasen |
| EP1797877A4 (en) | 2004-09-13 | 2010-12-15 | Eisai Co Ltd | JOINT USE OF A SULFONAMIDE-BASED COMPOUND AND AN ANGIOGENESIS INHIBITOR |
| US8772269B2 (en) | 2004-09-13 | 2014-07-08 | Eisai R&D Management Co., Ltd. | Use of sulfonamide-including compounds in combination with angiogenesis inhibitors |
| JP5414990B2 (ja) * | 2004-10-04 | 2014-02-12 | エフ．ホフマン−ラ ロシュ アーゲー | 糖尿病のための１１−β阻害剤としてのアルキルピリジン |
| JPWO2006054456A1 (ja) * | 2004-11-17 | 2008-05-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 二環式へテロ環含有スルホンアミド化合物の結晶 |
| JPWO2006090930A1 (ja) * | 2005-02-28 | 2008-07-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド化合物の新規併用 |
| JP5094394B2 (ja) * | 2005-04-20 | 2012-12-12 | 武田薬品工業株式会社 | 縮合複素環化合物 |
| EP2757099B1 (en) * | 2005-05-12 | 2017-08-23 | AbbVie Bahamas Limited | Apoptosis promoters |
| JPWO2007123274A1 (ja) | 2006-04-20 | 2009-09-10 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド化合物の新規感受性マーカー |
| UA97257C2 (en) * | 2006-10-19 | 2012-01-25 | Такеда Фармасьютикал Компани Лимитед | Indole derivatives |
| ES2705599T3 (es) | 2007-04-16 | 2019-03-26 | Abbvie Inc | Indoles sustituidos en la posición 7 como inhibidores de mcl-1 |
| JP5323834B2 (ja) * | 2007-08-17 | 2013-10-23 | エルジー・ライフ・サイエンシーズ・リミテッド | 細胞壊死阻害剤としてのインドール化合物 |
| RU2460525C2 (ru) | 2008-01-04 | 2012-09-10 | Эл Джи Лайф Сайенсиз Лтд. | Производные индола и индазола, обладающие консервирующим действием по отношению к клеткам, тканям и органам |
| EP2229929B1 (en) | 2009-03-18 | 2017-06-14 | DENTSPLY DETREY GmbH | Temporary root canal sealer dispersion |
| TWI410408B (zh) * | 2010-03-16 | 2013-10-01 | Purzer Pharmaceutical Co Ltd | 苯磺醯胺衍生物及其醫藥組合物 |
| CN102199148A (zh) * | 2010-03-25 | 2011-09-28 | 瑞安大药厂股份有限公司 | 苯磺酰胺衍生物及其医药组合物 |
| WO2012056319A1 (en) * | 2010-10-27 | 2012-05-03 | Dynamix Pharmaceuticals Ltd. | Sulfonamides for the modulation of pkm2 |
| CN102875549B (zh) * | 2012-09-14 | 2015-11-04 | 浙江大学 | 7-芳（甲）胺基-5-胺基-6-氮杂吲哚衍生物及制备与用途 |
| WO2015026172A1 (ko) | 2013-08-22 | 2015-02-26 | 주식회사 엘지생명과학 | 세포괴사 저해제로서의 인돌아미드 화합물 |
| KR101986580B1 (ko) | 2013-08-22 | 2019-06-10 | 주식회사 엘지화학 | 세포괴사 저해제로서의 인돌 화합물 |
| WO2020210139A1 (en) * | 2019-04-10 | 2020-10-15 | Peloton Therapeutics, Inc. | Pyrazolesulfonamides as antitumor agents |
| WO2020256432A1 (ko) | 2019-06-19 | 2020-12-24 | 주식회사 엘지화학 | 인돌 또는 인다졸 화합물의 제조방법 |
| KR102389716B1 (ko) | 2019-06-19 | 2022-04-25 | 주식회사 엘지화학 | 인돌 또는 인다졸 화합물의 제조방법 |
| KR102389718B1 (ko) | 2019-06-19 | 2022-04-25 | 주식회사 엘지화학 | 인돌 또는 인다졸 화합물의 제조방법 |
| EP3971186B1 (en) | 2019-06-19 | 2023-08-02 | LG Chem, Ltd. | Preparation method for indole or indazole compound |
| WO2023064669A2 (en) * | 2021-09-21 | 2023-04-20 | The Trustees Of Princeton University | Inhibitors of the mtdh-snd1 protein complex for cancer therapy |
| MA54773B1 (fr) * | 2021-10-29 | 2023-10-31 | Univ Euro Mediterraneenne De Fes Uemf | Nouvelles familles de composés à base de sulfonamides pour le traitement du cancer du sein triple négatif |
| EP4573088A1 (en) * | 2022-08-15 | 2025-06-25 | Recursion Pharmaceuticals, Inc. | Heterocycle rbm39 modulators |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU509046A1 (ru) * | 1975-02-21 | 1984-06-23 | Всесоюзный научно-исследовательский химико-фармацевтический институт им.Серго Орджоникидзе | Производные 2-карбэтокси-3-аминоиндола,про вл ющие противовоспалительную активность, и способ их получени |
| JPS539256A (en) * | 1976-07-14 | 1978-01-27 | Hitachi Kiden Kogyo Kk | Two hook type club |
| DE3105850A1 (de) * | 1981-02-18 | 1982-08-19 | Horst, Hans Jörg, Priv.Doz.Dr., 2057 Reinbek | Mittel zum behandeln von tumoren |
| DE3247615A1 (de) * | 1982-12-23 | 1984-07-05 | Hoechst Ag, 6230 Frankfurt | Substituierte phenylsulfonyloxybenzimidazolcarbaminate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4610981A (en) * | 1985-02-11 | 1986-09-09 | American Cyanamid Company | N-[(1H-imidazol-1-yl) and (1H-1,2,4-triazol-1-yl)-alkyl]benzenesulfonamides and thromboxane synthetase/antihypertensive compositions |
| EP0215200B1 (en) * | 1985-06-24 | 1992-09-09 | Merck & Co. Inc. | Use of sulfanilamido quinoxalines in the treatment of neoplastic diseases |
| US4849563A (en) * | 1986-01-21 | 1989-07-18 | Yale University | Novel 1-alkyl-1-arenesulfonyl-2-alkoxycarbonylsulfenylhydrazines having antineoplastic activity |
| US4942263A (en) * | 1989-04-13 | 1990-07-17 | Eastman Kodak Company | Preparation of aldehydes |
| JP2790926B2 (ja) * | 1990-08-20 | 1998-08-27 | エーザイ株式会社 | スルホンアミド誘導体 |
| ATE167473T1 (de) * | 1990-08-20 | 1998-07-15 | Eisai Co Ltd | Sulfonamid-derivate |
| LU87814A1 (fr) * | 1990-09-27 | 1992-05-25 | Oreal | Composition cosmetique comportant une dispersion de vesicules lipidiques ainsi que des pigments melaniques,et son utilisation |
-
1994
- 1994-09-08 PT PT94926372T patent/PT673937E/pt unknown
- 1994-09-08 CN CNB011194561A patent/CN1221533C/zh not_active Expired - Fee Related
- 1994-09-08 AT AT94926372T patent/ATE255106T1/de active
- 1994-09-08 RU RU95112848A patent/RU2128648C1/ru not_active IP Right Cessation
- 1994-09-08 EP EP94926372A patent/EP0673937B1/en not_active Expired - Lifetime
- 1994-09-08 DK DK94926372T patent/DK0673937T3/da active
- 1994-09-08 DE DE69433353T patent/DE69433353T2/de not_active Expired - Lifetime
- 1994-09-08 HU HU9501363A patent/HU224069B1/hu not_active IP Right Cessation
- 1994-09-08 NZ NZ273073A patent/NZ273073A/en not_active IP Right Cessation
- 1994-09-08 CA CA002146961A patent/CA2146961C/en not_active Expired - Fee Related
- 1994-09-08 WO PCT/JP1994/001487 patent/WO1995007276A1/ja not_active Ceased
- 1994-09-08 CN CN94190672A patent/CN1079097C/zh not_active Expired - Fee Related
- 1994-09-08 KR KR1019950701862A patent/KR0174752B1/ko not_active Expired - Fee Related
- 1994-09-08 AU AU76237/94A patent/AU683492B2/en not_active Ceased
- 1994-09-08 RU RU96119782A patent/RU2121997C1/ru not_active IP Right Cessation
- 1994-09-08 ES ES94926372T patent/ES2206469T3/es not_active Expired - Lifetime
-
1995
- 1995-05-09 NO NO19951813A patent/NO303778B1/no not_active IP Right Cessation
-
1997
- 1997-01-17 US US08/785,610 patent/US5767283A/en not_active Expired - Lifetime
- 1997-04-09 AU AU17785/97A patent/AU711438B2/en not_active Ceased
-
1998
- 1998-09-07 KR KR1019980707044A patent/KR100188846B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2146961A1 (en) | 1995-03-16 |
| RU2121997C1 (ru) | 1998-11-20 |
| CN1491941A (zh) | 2004-04-28 |
| KR100188846B1 (en) | 1999-06-01 |
| EP0673937B1 (en) | 2003-11-26 |
| US5767283A (en) | 1998-06-16 |
| HU224069B1 (hu) | 2005-05-30 |
| AU7623794A (en) | 1995-03-27 |
| RU95112848A (ru) | 1997-03-20 |
| EP0673937A4 (en) | 1996-01-17 |
| KR0174752B1 (ko) | 1999-02-01 |
| AU711438B2 (en) | 1999-10-14 |
| EP0673937A1 (en) | 1995-09-27 |
| DE69433353D1 (de) | 2004-01-08 |
| AU683492B2 (en) | 1997-11-13 |
| HU9501363D0 (en) | 1995-06-28 |
| CA2146961C (en) | 2006-11-07 |
| ES2206469T3 (es) | 2004-05-16 |
| CN1079097C (zh) | 2002-02-13 |
| WO1995007276A1 (en) | 1995-03-16 |
| ATE255106T1 (de) | 2003-12-15 |
| DE69433353T2 (de) | 2004-09-09 |
| CN1114506A (zh) | 1996-01-03 |
| NO951813D0 (no) | 1995-05-09 |
| NO303778B1 (no) | 1998-08-31 |
| DK0673937T3 (da) | 2004-03-22 |
| KR950704304A (ko) | 1995-11-17 |
| NO951813L (no) | 1995-05-09 |
| NZ273073A (en) | 1996-09-25 |
| RU2128648C1 (ru) | 1999-04-10 |
| HUT71551A (en) | 1995-12-28 |
| AU1778597A (en) | 1997-08-14 |
| CN1221533C (zh) | 2005-10-05 |
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