ATE284407T1 - Pyrimidinderivate als markierte bindungspartner - Google Patents
Pyrimidinderivate als markierte bindungspartnerInfo
- Publication number
- ATE284407T1 ATE284407T1 AT98956393T AT98956393T ATE284407T1 AT E284407 T1 ATE284407 T1 AT E284407T1 AT 98956393 T AT98956393 T AT 98956393T AT 98956393 T AT98956393 T AT 98956393T AT E284407 T1 ATE284407 T1 AT E284407T1
- Authority
- AT
- Austria
- Prior art keywords
- binding partners
- pyrimidine derivatives
- labeled binding
- compounds
- methods
- Prior art date
Links
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/101—Modifications characterised by incorporating non-naturally occurring nucleotides, e.g. inosine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Dental Preparations (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/966,392 US6028183A (en) | 1997-11-07 | 1997-11-07 | Pyrimidine derivatives and oligonucleotides containing same |
| US08/966,875 US6007992A (en) | 1997-11-10 | 1997-11-10 | Pyrimidine derivatives for labeled binding partners |
| PCT/US1998/023119 WO1999024452A2 (en) | 1997-11-07 | 1998-10-30 | Pyrimidine derivatives for labeled binding partners |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE284407T1 true ATE284407T1 (de) | 2004-12-15 |
Family
ID=27130485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98956393T ATE284407T1 (de) | 1997-11-07 | 1998-10-30 | Pyrimidinderivate als markierte bindungspartner |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1027364B1 (de) |
| JP (1) | JP2001522860A (de) |
| AT (1) | ATE284407T1 (de) |
| AU (1) | AU1292899A (de) |
| CA (1) | CA2309340C (de) |
| DE (1) | DE69828080T2 (de) |
| WO (1) | WO1999024452A2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376669B1 (en) * | 1999-11-05 | 2002-04-23 | 3M Innovative Properties Company | Dye labeled imidazoquinoline compounds |
| JP2005504020A (ja) * | 2001-07-03 | 2005-02-10 | アイシス・ファーマシューティカルス・インコーポレーテッド | ヌクレアーゼ耐性キメラオリゴヌクレオチド |
| US7070933B2 (en) | 2001-09-28 | 2006-07-04 | Gen-Probe Incorporated | Inversion probes |
| JP2003199568A (ja) * | 2002-01-10 | 2003-07-15 | Nichirei Corp | Ｄｎａ増幅反応の効率向上方法 |
| JP4322554B2 (ja) * | 2003-05-19 | 2009-09-02 | 株式会社ニチレイフーズ | Ｄｎａ増幅反応の効率向上方法 |
| EP3424939A1 (de) | 2009-03-02 | 2019-01-09 | Alnylam Pharmaceuticals Inc. | Chemische nukleinsäuremodifikationen |
| WO2011047323A2 (en) | 2009-10-16 | 2011-04-21 | Rib-X Pharmaceuticals, Inc. | Antimicrobial compounds and methods of making and using the same |
| BR112012008759A2 (pt) | 2009-10-16 | 2020-08-25 | Rib-X Pharmaceuticals, Inc. | compostos antimicrobianos e métodos de fabricação e uso dos mesmos |
| CN105646370A (zh) * | 2009-10-16 | 2016-06-08 | 梅琳塔治疗公司 | 抗微生物化合物和其制备和使用方法 |
| WO2011123621A2 (en) | 2010-04-01 | 2011-10-06 | Alnylam Pharmaceuticals Inc. | 2' and 5' modified monomers and oligonucleotides |
| JP6129844B2 (ja) | 2011-09-14 | 2017-05-17 | ラナ セラピューティクス インコーポレイテッド | 多量体オリゴヌクレオチド化合物 |
| EP2781523A1 (de) | 2013-03-18 | 2014-09-24 | Miltenyi Biotec GmbH | Lipophile Oligonukleotid-Analoga |
| EP3039025A4 (de) | 2013-09-09 | 2017-05-31 | Melinta Therapeutics, Inc. | Antimikrobielle verbindungen und verfahren zur herstellung und verwendung davon |
| MX2016003046A (es) | 2013-09-09 | 2016-09-08 | Melinta Therapeutics Inc | Compuestos antimicrobianos y métodos de fabricación y utilización de los mismos. |
| WO2015191303A2 (en) * | 2014-06-10 | 2015-12-17 | Agilent Technologies, Inc. | Protecting groups for "z nucleotide" and methods thereof |
| CN107922418A (zh) | 2015-03-11 | 2018-04-17 | 梅琳塔治疗公司 | 抗微生物化合物及制备和使用所述化合物的方法 |
| JP2019515041A (ja) | 2016-05-06 | 2019-06-06 | メリンタ セラピューティクス、 インコーポレイテッドＭｅｌｉｎｔａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | 抗菌剤ならびにそれを作製および使用する方法 |
| JP6894747B2 (ja) | 2017-04-19 | 2021-06-30 | キヤノン株式会社 | 重合体 |
| RU2731381C1 (ru) * | 2019-04-26 | 2020-09-02 | Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) | Нуклеозидные производные 1,3-диаза-2-оксофеноксазина в качестве ингибиторов репликации герпесвирусов. |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5502177A (en) * | 1993-09-17 | 1996-03-26 | Gilead Sciences, Inc. | Pyrimidine derivatives for labeled binding partners |
-
1998
- 1998-10-30 DE DE69828080T patent/DE69828080T2/de not_active Expired - Lifetime
- 1998-10-30 WO PCT/US1998/023119 patent/WO1999024452A2/en not_active Ceased
- 1998-10-30 JP JP2000520460A patent/JP2001522860A/ja not_active Withdrawn
- 1998-10-30 CA CA002309340A patent/CA2309340C/en not_active Expired - Lifetime
- 1998-10-30 EP EP98956393A patent/EP1027364B1/de not_active Expired - Lifetime
- 1998-10-30 AT AT98956393T patent/ATE284407T1/de not_active IP Right Cessation
- 1998-10-30 AU AU12928/99A patent/AU1292899A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999024452A9 (en) | 1999-08-12 |
| EP1027364B1 (de) | 2004-12-08 |
| CA2309340C (en) | 2006-02-21 |
| WO1999024452A3 (en) | 1999-09-16 |
| DE69828080D1 (de) | 2005-01-13 |
| CA2309340A1 (en) | 1999-05-20 |
| DE69828080T2 (de) | 2005-11-24 |
| AU1292899A (en) | 1999-05-31 |
| EP1027364A2 (de) | 2000-08-16 |
| WO1999024452A2 (en) | 1999-05-20 |
| WO1999024452A8 (en) | 1999-10-21 |
| JP2001522860A (ja) | 2001-11-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |