ATE284414T1 - Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen - Google Patents

Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen

Info

Publication number
ATE284414T1
ATE284414T1 AT98942796T AT98942796T ATE284414T1 AT E284414 T1 ATE284414 T1 AT E284414T1 AT 98942796 T AT98942796 T AT 98942796T AT 98942796 T AT98942796 T AT 98942796T AT E284414 T1 ATE284414 T1 AT E284414T1
Authority
AT
Austria
Prior art keywords
def
cdna
diagnostic
gene
therapeutic applications
Prior art date
Application number
AT98942796T
Other languages
English (en)
Inventor
Lydie Bougueleret
Ilya Chumakov
Original Assignee
Genset Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset Sa filed Critical Genset Sa
Application granted granted Critical
Publication of ATE284414T1 publication Critical patent/ATE284414T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4721—Cationic antimicrobial peptides, e.g. defensins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Birds (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
AT98942796T 1997-08-29 1998-08-28 Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen ATE284414T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710823A FR2767832B1 (fr) 1997-08-29 1997-08-29 Polypeptide defensine humaine def-x, adn genomique et adnc, composition les contenant et applications au diagnostic et au traitement therapeutique
PCT/FR1998/001864 WO1999011663A1 (fr) 1997-08-29 1998-08-28 DEFENSINE HUMAINE DEF-X, GENE ET cDNA, COMPOSITION LES CONTENANT ET APPLICATIONS AU DIAGNOSTIC ET A LA THERAPIE

Publications (1)

Publication Number Publication Date
ATE284414T1 true ATE284414T1 (de) 2004-12-15

Family

ID=9510617

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98942796T ATE284414T1 (de) 1997-08-29 1998-08-28 Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen

Country Status (11)

Country Link
US (3) US6329340B1 (de)
EP (1) EP1009767B1 (de)
JP (1) JP2001514264A (de)
AT (1) ATE284414T1 (de)
AU (1) AU759482B2 (de)
CA (1) CA2299560C (de)
DE (1) DE69828063T2 (de)
ES (1) ES2230714T3 (de)
FR (1) FR2767832B1 (de)
PT (1) PT1009767E (de)
WO (1) WO1999011663A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984622B2 (en) * 1998-03-25 2006-01-10 The Regents Of The University Of California Use of lipopolysaccharides to manage corneal infections and wounds
US6335318B1 (en) 1999-05-10 2002-01-01 The Regents Of The University Of California Antimicrobial theta defensins and methods of using same
WO2003070176A2 (en) * 2002-02-19 2003-08-28 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Modified defensins and their use
US7119070B2 (en) 2002-04-30 2006-10-10 The Regents Of The University Of California Antimicrobial theta defensins, analogs thereof, and methods of use
CA2487895A1 (en) * 2002-05-31 2003-12-11 Ciphergen Biosystems, Inc. Defensins: use as antiviral agents
US20040096820A1 (en) * 2002-05-31 2004-05-20 Ciphergen Biosystems, Inc. Comparative proteomics of progressor and nonprogressor populations
US20060166295A1 (en) * 2002-07-01 2006-07-27 James Woods Method for determination of likelihood of occurrence of preterm labor in pregnant females
GB0223655D0 (en) 2002-10-10 2002-11-20 Mabtech Ab Method of diagnosis
NZ540506A (en) * 2002-12-19 2008-09-26 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
EP1613966A2 (de) 2003-04-08 2006-01-11 Colotech A/S Verfahren zum nachweis von kolorektalem krebs in menschlichen proben
US9044438B2 (en) 2005-06-17 2015-06-02 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US8202835B2 (en) 2005-06-17 2012-06-19 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US10967031B2 (en) 2010-12-28 2021-04-06 Kamedis Ltd. Synergistic herbal compositions with prebiotic properties for treatment of skin infections, allergies and inflammation
KR101947126B1 (ko) 2010-12-28 2019-02-13 카메디스 리미티드 감염의 치료 및 예방을 위한 식물 추출물
ES2903108T3 (es) * 2014-06-18 2022-03-31 Medicell Tech Llc Composiciones y métodos de estimulación de células madre
RU2597789C2 (ru) * 2014-11-10 2016-09-20 Илья Владимирович Духовлинов Анальгетическое средство на основе плазмидной днк, кодирующей hnp-1, либо hnp-2, либо hnp-3 (варианты)
WO2024036134A2 (en) * 2022-08-08 2024-02-15 Sri International Defensin proteins for infection assessment

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032574A (en) * 1988-05-26 1991-07-16 Invitron Corporation Novel antimicrobial peptide
US5242902A (en) * 1989-09-06 1993-09-07 The Regents Of The University Of California Defensin peptide compositions and methods for their use
WO1993024513A1 (en) * 1992-05-22 1993-12-09 The Children's Hospital Of Philadelphia Gastrointestinal defensins, cdna sequences and method for the production and use thereof
US5459235A (en) * 1993-03-19 1995-10-17 The Regents Of The University Of California Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils
US5550109A (en) * 1994-05-24 1996-08-27 Magainin Pharmaceuticals Inc. Inducible defensin peptide from mammalian epithelia

Also Published As

Publication number Publication date
AU759482B2 (en) 2003-04-17
US6960441B2 (en) 2005-11-01
AU9079898A (en) 1999-03-22
EP1009767B1 (de) 2004-12-08
US20020182703A1 (en) 2002-12-05
US7105651B2 (en) 2006-09-12
DE69828063D1 (de) 2005-01-13
DE69828063T2 (de) 2005-12-01
CA2299560A1 (fr) 1999-03-11
FR2767832B1 (fr) 2001-08-10
EP1009767A1 (de) 2000-06-21
WO1999011663A1 (fr) 1999-03-11
PT1009767E (pt) 2005-02-28
US6329340B1 (en) 2001-12-11
CA2299560C (fr) 2012-03-20
ES2230714T3 (es) 2005-05-01
US20020115151A1 (en) 2002-08-22
JP2001514264A (ja) 2001-09-11
FR2767832A1 (fr) 1999-03-05

Similar Documents

Publication Publication Date Title
ATE284414T1 (de) Menschliche defensin def-x, gen und cdna, deren enthaltende zusammensetzungen und deren diagnostische und therapeutische anwendungen
UA66417C2 (en) Recombinant adenovirus affecting canines, pharmaceutical composition
TR200200938T2 (tr) CCR5 modülatörleri olarak piperidinler
BRPI0412993A (pt) inibidores da atividade da akt
PT1131065E (pt) Fumaratos dialquilicos para o tratamento de doencas autoimunes
BRPI0412845A (pt) herpes-vìrus, uso de um vìrus, composição farmacêutica, e, método de tratamento de um tumor em um indivìduo em necessidade do mesmo
BR0211546A (pt) Composição farmacêutica e/ou de diagnóstico e uso de microrganismo ou célula
DE69433562D1 (de) Prosaposin und cytokinabhängige peptide als therapeutisch wirksame mittel
RU95108217A (ru) Дефектный рекомбинантный аденовирус, линия клеток, фармацевтическая композиция
ATE389724T1 (de) Menschliche dnase i hyperaktive varianten
GEP19991538B (en) Derivatives of Erytromycin and Pharmaceutical Composition on their Basis
TR200103560T2 (tr) Göğüs kanserinin teşhis ve tedavisi için bileşimler ve bunların kullanımı
ATE293700T1 (de) Adenovirus mit glutathion peroxydate gene
NZ515964A (en) A method for the prophylaxis and/or treatment of medical disorders
BR0110049A (pt) Agonista de cxcr4, uso de um agonista de cxcr4, e composição farmacêutica
MXPA05008704A (es) Proteinas de fusion de muteinas de interferon alfa con propiedades mejoradas.
DE69839702D1 (de) Neue antimikrobielle polypeptide und verfahren für ihre verwendung.
CA2388910A1 (en) Antimicrobial activity of the first cationic cluster of human lactoferrin
AR008847A1 (es) Construcciones de acidos nucleicos para la expresion regulada de un transgen en una celula hospedante para uso en la terapia fenica y lamanipulacion genetica, una celula aislada que los comprende y una composicion farmaceutica
BR0009170A (pt) ácidos nucléicos akt, polipeptìdeos e uso dos mesmos
BR0010563A (pt) Composições isoladas de células da pele e métodos para seu uso
BR0206852A (pt) Conjugados de polìmero de neublastina e métodos para uso dos mesmos
BR9710899A (pt) Composição compreendendo mupirocin e clorohexidina.
CA2265444A1 (en) Tnf-beta-like protein for treating prostate cancer, and related nucleic acid molecules, pharmaceutical compositions and methods
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1009767

Country of ref document: EP