ATE286725T1 - Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe - Google Patents
Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabeInfo
- Publication number
- ATE286725T1 ATE286725T1 AT99950595T AT99950595T ATE286725T1 AT E286725 T1 ATE286725 T1 AT E286725T1 AT 99950595 T AT99950595 T AT 99950595T AT 99950595 T AT99950595 T AT 99950595T AT E286725 T1 ATE286725 T1 AT E286725T1
- Authority
- AT
- Austria
- Prior art keywords
- rivastigmine
- active ingredients
- controlled release
- medicinal preparations
- new oral
- Prior art date
Links
- XSVMFMHYUFZWBK-NSHDSACASA-N Rivastigmine Chemical compound CCN(C)C(=O)OC1=CC=CC([C@H](C)N(C)C)=C1 XSVMFMHYUFZWBK-NSHDSACASA-N 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 238000013270 controlled release Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229960004136 rivastigmine Drugs 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9821298.8A GB9821298D0 (en) | 1998-10-01 | 1998-10-01 | Organic compoundsq |
| GBGB9821299.6A GB9821299D0 (en) | 1998-10-01 | 1998-10-01 | Organic compounds |
| GBGB9826654.7A GB9826654D0 (en) | 1998-12-03 | 1998-12-03 | Organic compounds |
| GBGB9827624.9A GB9827624D0 (en) | 1998-12-16 | 1998-12-16 | Organic compounds |
| GBGB9907822.2A GB9907822D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
| GBGB9907823.0A GB9907823D0 (en) | 1999-04-06 | 1999-04-06 | Organic compounds |
| PCT/EP1999/007298 WO2000019985A2 (en) | 1998-10-01 | 1999-10-01 | New sustained release oral formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286725T1 true ATE286725T1 (de) | 2005-01-15 |
Family
ID=27547321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99950595T ATE286725T1 (de) | 1998-10-01 | 1999-10-01 | Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US20010033866A1 (de) |
| EP (1) | EP1121104B1 (de) |
| JP (1) | JP4012689B2 (de) |
| KR (1) | KR100603900B1 (de) |
| CN (1) | CN1406126A (de) |
| AT (1) | ATE286725T1 (de) |
| AU (1) | AU764866B2 (de) |
| BR (1) | BR9914251A (de) |
| CA (1) | CA2342340C (de) |
| CZ (1) | CZ302888B6 (de) |
| DE (1) | DE69923200T2 (de) |
| ES (1) | ES2237163T3 (de) |
| HK (1) | HK1052473A1 (de) |
| HU (1) | HUP0103883A3 (de) |
| ID (1) | ID27504A (de) |
| IL (2) | IL141762A0 (de) |
| NO (1) | NO331689B1 (de) |
| NZ (1) | NZ510683A (de) |
| PL (1) | PL196945B1 (de) |
| PT (1) | PT1121104E (de) |
| SK (1) | SK285250B6 (de) |
| TR (1) | TR200100931T2 (de) |
| WO (1) | WO2000019985A2 (de) |
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| EP1121104B1 (de) * | 1998-10-01 | 2005-01-12 | Novartis AG | Neue oral anzuwendende arzneizubereitungen für rivastigmine mit kontrollierter wirkstoffabgabe |
| AU1738800A (en) * | 1998-11-23 | 2000-06-13 | Bonnie Davis | Dosage formulations for acetylcholinesterase inhibitors |
| EP1206250A2 (de) * | 1999-08-26 | 2002-05-22 | ELAN CORPORATION, Plc | Pharmazeutische zusammensetzungen mit verschiedener wirkstoffabgabezeit |
| GB9923045D0 (en) * | 1999-09-29 | 1999-12-01 | Novartis Ag | New oral formulations |
| ATE361060T1 (de) * | 2000-09-29 | 2007-05-15 | Solvay Pharm Bv | Ionenstärkenunabhängige pharmazeutische formulierung mit verzögerter freisetzung |
| JP5023412B2 (ja) * | 2001-05-09 | 2012-09-12 | 吉澤石灰工業株式会社 | ホルムアルデヒド廃液の処理剤 |
| DE60223695T2 (de) * | 2001-09-14 | 2008-10-30 | Scolr, Inc., Redmond | Aminosäure-modulierte dosierform mit verlängerter freisetzung |
| JP2005525299A (ja) * | 2001-09-14 | 2005-08-25 | スコラー インコーポレイテッド | アミノ酸調節性の長期放出投薬形態 |
| KR100453288B1 (ko) * | 2002-03-12 | 2004-10-21 | 한국화학연구원 | 약물의 제어 방출을 위한 스퀴즈-유형의 삼투성 약물 전달장치 |
| JP2005534710A (ja) * | 2002-08-07 | 2005-11-17 | ノバルティス アクチエンゲゼルシャフト | Apoe遺伝子型を基準とした痴呆を処置するための方法 |
| JP2006522011A (ja) * | 2003-04-07 | 2006-09-28 | ジュロックス プロプライエタリー リミテッド | 安定なカルプロフェン組成物 |
| WO2004100929A1 (en) * | 2003-05-12 | 2004-11-25 | Synergia Pharma, Inc. | Threo-dops controlled release formulation |
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| RU2622082C2 (ru) | 2011-11-14 | 2017-06-09 | Нестек С.А. | Анализы и способы выбора режима лечения пациента с депрессией |
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| CN104884059B (zh) | 2012-11-30 | 2018-08-10 | 罗切斯特大学 | 用于hiv/aids治疗的混合谱系激酶抑制剂 |
| KR20150098605A (ko) | 2012-12-21 | 2015-08-28 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 퀴놀린 유도체의 비정질 형태 및 그의 제조방법 |
| NZ714049A (en) | 2013-05-14 | 2020-05-29 | Eisai R&D Man Co Ltd | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds |
| AU2014307803A1 (en) | 2013-08-16 | 2016-03-10 | Universiteit Maastricht | Treatment of cognitive impairment with PDE4 inhibitor |
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| CN103877063A (zh) * | 2014-03-24 | 2014-06-25 | 张绪伟 | 一种重酒石酸卡巴拉汀胶囊及其制备方法 |
| PT3524595T (pt) | 2014-08-28 | 2022-09-19 | Eisai R&D Man Co Ltd | Derivado de quinolina altamente puro e método para produção do mesmo |
| LT3263106T (lt) | 2015-02-25 | 2024-01-10 | Eisai R&D Management Co., Ltd. | Chinolino darinių kartumo sumažinimo būdas |
| KR102662228B1 (ko) | 2015-03-04 | 2024-05-02 | 머크 샤프 앤드 돔 코포레이션 | 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합 |
| KR101990951B1 (ko) * | 2015-04-27 | 2019-06-20 | 주식회사 네비팜 | 리바스티그민 함유 서방출 의약조성물 |
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| WO2019039836A2 (ko) * | 2017-08-22 | 2019-02-28 | 아주대학교산학협력단 | 퇴행성 신경질환 치료용 복합 제형 조성물 |
| KR20190036370A (ko) | 2017-09-27 | 2019-04-04 | 서원대학교산학협력단 | 약물의 서방성 제형을 위한 약물전달체 |
| HUE065984T2 (hu) * | 2018-07-30 | 2024-07-28 | Biothea Pharma Inc | Kristályos epinefrin-malonát só |
| CN112546037A (zh) * | 2020-12-08 | 2021-03-26 | 苏州大学 | 卡巴拉汀在制备抗辐射药中的应用 |
| CN113398273B (zh) * | 2021-05-14 | 2022-07-19 | 广西壮族自治区中国科学院广西植物研究所 | 木聚糖衍生物作为亲水性缓释材料在制备药物缓释片中的应用 |
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| US4014335A (en) * | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
| USRE34990E (en) * | 1986-08-07 | 1995-07-04 | Ciba-Geigy Corporation | Oral therapeutic system having systemic action |
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| NL195004C (nl) | 1987-03-04 | 2003-11-04 | Novartis Ag | Fenylcarbamaat bevattend farmaceutisch preparaat. |
| US5472710A (en) * | 1988-04-16 | 1995-12-05 | Schwarz Pharma Ag | Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture |
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| GB9800526D0 (en) * | 1998-01-12 | 1998-03-11 | Ciba Geigy Ag | Organic compounds |
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| US6534541B1 (en) | 1999-10-19 | 2003-03-18 | Novartis Ag | Treatment of ocular disorders |
-
1999
- 1999-10-01 EP EP99950595A patent/EP1121104B1/de not_active Expired - Lifetime
- 1999-10-01 ID IDW20010671A patent/ID27504A/id unknown
- 1999-10-01 CN CN99811633A patent/CN1406126A/zh active Pending
- 1999-10-01 HK HK03104925.9A patent/HK1052473A1/zh unknown
- 1999-10-01 PL PL348734A patent/PL196945B1/pl not_active IP Right Cessation
- 1999-10-01 HU HU0103883A patent/HUP0103883A3/hu unknown
- 1999-10-01 WO PCT/EP1999/007298 patent/WO2000019985A2/en not_active Ceased
- 1999-10-01 CA CA002342340A patent/CA2342340C/en not_active Expired - Fee Related
- 1999-10-01 PT PT99950595T patent/PT1121104E/pt unknown
- 1999-10-01 BR BR9914251-1A patent/BR9914251A/pt not_active Application Discontinuation
- 1999-10-01 ES ES99950595T patent/ES2237163T3/es not_active Expired - Lifetime
- 1999-10-01 DE DE69923200T patent/DE69923200T2/de not_active Expired - Lifetime
- 1999-10-01 KR KR1020017003384A patent/KR100603900B1/ko not_active Expired - Fee Related
- 1999-10-01 AU AU63321/99A patent/AU764866B2/en not_active Ceased
- 1999-10-01 IL IL14176299A patent/IL141762A0/xx unknown
- 1999-10-01 NZ NZ510683A patent/NZ510683A/en not_active IP Right Cessation
- 1999-10-01 TR TR2001/00931T patent/TR200100931T2/xx unknown
- 1999-10-01 AT AT99950595T patent/ATE286725T1/de active
- 1999-10-01 CZ CZ20011155A patent/CZ302888B6/cs not_active IP Right Cessation
- 1999-10-01 SK SK439-2001A patent/SK285250B6/sk not_active IP Right Cessation
- 1999-10-01 JP JP2000573347A patent/JP4012689B2/ja not_active Expired - Fee Related
-
2001
- 2001-03-01 IL IL141762A patent/IL141762A/en unknown
- 2001-03-22 NO NO20011471A patent/NO331689B1/no not_active IP Right Cessation
- 2001-03-27 US US09/818,690 patent/US20010033866A1/en not_active Abandoned
-
2002
- 2002-04-08 US US10/118,183 patent/US6565883B2/en not_active Expired - Fee Related
-
2003
- 2003-03-31 US US10/403,146 patent/US20030203025A1/en not_active Abandoned
-
2005
- 2005-04-14 US US11/105,967 patent/US20050175706A1/en not_active Abandoned
-
2006
- 2006-11-03 US US11/592,853 patent/US20070053982A1/en not_active Abandoned
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