ES2061591T3 - Administracion intranasal de polipeptidos en forma pulverizada. - Google Patents

Administracion intranasal de polipeptidos en forma pulverizada.

Info

Publication number
ES2061591T3
ES2061591T3 ES88117029T ES88117029T ES2061591T3 ES 2061591 T3 ES2061591 T3 ES 2061591T3 ES 88117029 T ES88117029 T ES 88117029T ES 88117029 T ES88117029 T ES 88117029T ES 2061591 T3 ES2061591 T3 ES 2061591T3
Authority
ES
Spain
Prior art keywords
polypeptides
intranasal administration
sprayed form
biologically active
active polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES88117029T
Other languages
English (en)
Inventor
Brian H Vickery
Cherng-Chyi Fu
Eric J Benjamin
Lynda M Sanders
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Application granted granted Critical
Publication of ES2061591T3 publication Critical patent/ES2061591T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPUESTOS FARMACEUTICOS DE POLIPEPTIDOS ACTIVOS BIOLOGICAMENTE EN FORMA PULVURULENTA APROPIADOS PARA ADMINISTRACION NASAL, COMPRENDEN UNA CANTIDAD TERAPEUTICA EFECTIVA DE POLIPEPTIDOS BIOLOGICAMENTE ACTIVOS Y UN POLISACARIDO SOLUBLE EN AGUA.
ES88117029T 1987-10-15 1988-10-13 Administracion intranasal de polipeptidos en forma pulverizada. Expired - Lifetime ES2061591T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10967887A 1987-10-15 1987-10-15

Publications (1)

Publication Number Publication Date
ES2061591T3 true ES2061591T3 (es) 1994-12-16

Family

ID=22328950

Family Applications (1)

Application Number Title Priority Date Filing Date
ES88117029T Expired - Lifetime ES2061591T3 (es) 1987-10-15 1988-10-13 Administracion intranasal de polipeptidos en forma pulverizada.

Country Status (11)

Country Link
US (3) US6521597B1 (es)
EP (1) EP0312052B1 (es)
JP (1) JP2851627B2 (es)
KR (1) KR890006252A (es)
AT (1) ATE99543T1 (es)
AU (1) AU623609B2 (es)
CA (1) CA1336401C (es)
DE (1) DE3886880T2 (es)
ES (1) ES2061591T3 (es)
NZ (1) NZ226557A (es)
ZA (1) ZA887658B (es)

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US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
PT806945E (pt) 1994-12-22 2003-09-30 Astrazeneca Ab Preparacao terapeutica para inalacao que contem a hormona paratiroide, hpt
US6524557B1 (en) 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
WO1996019198A1 (en) 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol drug formulations
JP3098401B2 (ja) * 1995-07-12 2000-10-16 株式会社エルティーティー研究所 経鼻投与用製剤
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US7772220B2 (en) 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
WO2004028444A2 (en) * 1999-06-02 2004-04-08 Scantibodies Laboratory, Inc. Parathyroid hormone antagonists and uses thereof
US20080108086A1 (en) * 1999-06-02 2008-05-08 Cantor Thomas L Parathyroid hormone antagonists and uses thereof
CN100558407C (zh) 2000-02-04 2009-11-11 柳署弘 制备含有胆汁酸的澄清水溶液剂型
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CN103755800B (zh) * 2004-02-02 2016-02-24 Ambrx公司 经修饰的人类生长激素多肽与其用途
WO2006016530A1 (ja) 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
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US7148067B2 (en) * 2004-08-31 2006-12-12 The Board Of Trustees Of The University Of Illinois Thromboplastin reagents
US7115561B2 (en) * 2004-09-22 2006-10-03 Patterson James A Medicament composition and method of administration
ATE506955T1 (de) 2004-10-15 2011-05-15 Seo Hong Yoo Zusammensetzungen zur verringerung der toxizität von cisplatin, carboplatin und oxaliplatin
KR100834735B1 (ko) * 2004-11-15 2008-06-09 김두만 부신피질 기능 부전증 치료용 부신피질 자극 호르몬의비강 분무 제형
US20080260858A1 (en) * 2005-02-16 2008-10-23 The Board Of Trustees Of The University Of Illnois Universal Procoagulant
WO2006096345A2 (en) * 2005-03-04 2006-09-14 The Board Of Trustees Of The University Of Illinois Coagulation and fibrinolytic cascades modulator
US20080184618A1 (en) * 2005-08-03 2008-08-07 Amcol International Virus-Interacting Layered Phyllosilicates and Methods of Use
US20070031512A1 (en) * 2005-08-03 2007-02-08 Amcol International Corporation Virus-interacting layered phyllosilicates and methods of inactivating viruses
US20100272769A1 (en) * 2005-08-03 2010-10-28 Amcol International Virus-, Bacteria-, and Fungi-Interacting Layered Phyllosilicates and Methods of Use
WO2007025286A2 (en) * 2005-08-26 2007-03-01 The Board Of Trustees Of The Leland Stanford Junior University Therapy procedure for drug delivery for trigeminal pain
WO2008005577A2 (en) * 2006-07-07 2008-01-10 University Of South Florida Compositions of polyphenols and methods of use
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PL2167069T3 (pl) 2007-05-23 2012-04-30 Amcol International Corp Krzemiany warstwowe oddziałujące z cholesterolem oraz sposoby zmniejszania hipercholesterolemii u ssaka
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WO2009046194A2 (en) * 2007-10-05 2009-04-09 The Board Of Trustees Of The University Of Illinois Fibrin sealant
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MX2018012351A (es) 2016-04-12 2019-02-07 Trigemina Inc Formulaciones de oxitocina que contienen magnesio y metodos de uso.
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CN110279656B (zh) * 2019-07-11 2021-11-09 温州医科大学 一种用于缓解鼻腔干燥的组合物及其制备方法和使用方法
US20230233635A1 (en) 2020-05-26 2023-07-27 Rhodes Technologies Cannabinoid compositions and dosage forms for intranasal or inhalational delivery

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Also Published As

Publication number Publication date
DE3886880T2 (de) 1994-07-14
JPH01132532A (ja) 1989-05-25
EP0312052A1 (en) 1989-04-19
US20030181387A1 (en) 2003-09-25
US20050089480A1 (en) 2005-04-28
EP0312052B1 (en) 1994-01-05
ZA887658B (en) 1990-06-27
US6815424B2 (en) 2004-11-09
NZ226557A (en) 1990-07-26
AU623609B2 (en) 1992-05-21
KR890006252A (ko) 1989-06-12
AU2375188A (en) 1989-06-01
DE3886880D1 (de) 1994-02-17
CA1336401C (en) 1995-07-25
US6521597B1 (en) 2003-02-18
ATE99543T1 (de) 1994-01-15
JP2851627B2 (ja) 1999-01-27

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