ATE288743T1 - Pharmazeutische trägervorrichtung welche zur verabreichung von wirkstoffen an schleimhautoberflächen geeignet ist - Google Patents

Pharmazeutische trägervorrichtung welche zur verabreichung von wirkstoffen an schleimhautoberflächen geeignet ist

Info

Publication number
ATE288743T1
ATE288743T1 AT99922753T AT99922753T ATE288743T1 AT E288743 T1 ATE288743 T1 AT E288743T1 AT 99922753 T AT99922753 T AT 99922753T AT 99922753 T AT99922753 T AT 99922753T AT E288743 T1 ATE288743 T1 AT E288743T1
Authority
AT
Austria
Prior art keywords
administration
active ingredients
device suitable
pharmaceutical carrier
carrier device
Prior art date
Application number
AT99922753T
Other languages
English (en)
Inventor
Gilles H Tapolsky
David W Osborne
Original Assignee
Virotex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virotex Corp filed Critical Virotex Corp
Application granted granted Critical
Publication of ATE288743T1 publication Critical patent/ATE288743T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Vending Machines For Individual Products (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT99922753T 1998-04-29 1999-04-29 Pharmazeutische trägervorrichtung welche zur verabreichung von wirkstoffen an schleimhautoberflächen geeignet ist ATE288743T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6970398A 1998-04-29 1998-04-29
PCT/US1999/009378 WO1999055312A2 (en) 1998-04-29 1999-04-29 Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces

Publications (1)

Publication Number Publication Date
ATE288743T1 true ATE288743T1 (de) 2005-02-15

Family

ID=22090679

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99922753T ATE288743T1 (de) 1998-04-29 1999-04-29 Pharmazeutische trägervorrichtung welche zur verabreichung von wirkstoffen an schleimhautoberflächen geeignet ist

Country Status (11)

Country Link
US (1) US20080254105A1 (de)
EP (1) EP1079813B1 (de)
JP (3) JP2002512950A (de)
AT (1) ATE288743T1 (de)
AU (1) AU746339B2 (de)
CA (1) CA2329128C (de)
DE (1) DE69923675T2 (de)
DK (1) DK1079813T3 (de)
ES (1) ES2237104T3 (de)
PT (1) PT1079813E (de)
WO (1) WO1999055312A2 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
JP2003520191A (ja) * 1998-09-08 2003-07-02 ワトソン ファーマシューティカルズ， インコーポレイテッド 薬物の親水性塩類を含有する感圧接着剤マトリックスパッチの製造方法
DE19954421A1 (de) * 1999-11-12 2001-05-31 Lohmann Therapie Syst Lts Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
ATE438418T1 (de) 2001-05-01 2009-08-15 Av Topchiev Inst Petrochemical Hydrogel-zusammensetzungen
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US6585997B2 (en) * 2001-08-16 2003-07-01 Access Pharmaceuticals, Inc. Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds
US20060073174A1 (en) * 2001-08-16 2006-04-06 Access Pharmaceuticals, Inc. Adherent and erodible film to treat a moist surface of a body tissue
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US7425292B2 (en) * 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
DE10252726B4 (de) * 2002-11-13 2008-05-08 Lts Lohmann Therapie-Systeme Ag Mehrschichtiges transmucosales therapeutisches System
IL153124A (en) * 2002-11-27 2010-06-30 Herbal Synthesis Corp Solid composition that can be glued to the lining
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7306812B2 (en) 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
MXPA06001776A (es) * 2003-08-15 2007-09-07 Qlt Usa Inc Sistema de suministro de farmaco transmucosal biocorrosivo, adhesivo.
DE10358748A1 (de) 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Darreichungsform basierend auf vernetzten hydrophilen Polymeren
KR20070007299A (ko) 2004-01-30 2007-01-15 코리움 인터네셔널, 인크. 활성제의 전달을 위한 급속 용해 필름
EP1751225B1 (de) * 2004-03-19 2009-08-05 The Tapemark Company Thermoplastische filme und herstellungsverfahren dafür
AU2007211734A1 (en) * 2006-02-02 2007-08-09 Leo Pharma A/S A topical composition comprising an antibacterial substance
ES2577390T3 (es) 2006-07-21 2016-07-14 Biodelivery Sciences International, Inc. Dispositivos de administración transmucosa con mayor captación
US10265265B2 (en) 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
US20080292683A1 (en) * 2007-05-24 2008-11-27 Monosolrx, Llc. Film shreds and delivery system incorporating same
EP2008651A1 (de) * 2007-06-26 2008-12-31 Drug Delivery Solutions Limited Biologisch erodierbares Patch
WO2009088726A2 (en) 2007-12-31 2009-07-16 Acclarent, Inc. Mucosal tissue dressing and method of use
EP2299970A2 (de) * 2008-06-30 2011-03-30 Coloplast A/S Aphthenpflaster
JP5284070B2 (ja) * 2008-12-12 2013-09-11 救急薬品工業株式会社 口腔内粘膜貼付製剤
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
US9017718B2 (en) * 2009-05-21 2015-04-28 Bionex Pharmaceuticals Llc Dual and single layer dosage forms
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
CN102630160B (zh) * 2009-09-16 2014-05-07 株式会社三养生物制药 透皮递送系统、其制备方法以及使用所述系统的透皮递送方法
EP3064199B1 (de) * 2010-04-02 2023-12-20 Buzzz Pharmaceuticals Limited Missbrauchssichere transdermale formulierungen von opiat-agonisten und -agonist-antagonisten
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US9610245B2 (en) 2011-03-14 2017-04-04 Drug Delivery Solutions Limited Ophthalmic composition
MX352959B (es) 2011-08-18 2017-12-15 Biodelivery Sciences Int Inc Dispositivos mucoadhesivos resistentes al abuso para el suministro de buprenorfina.
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
CN109260465A (zh) 2012-11-14 2019-01-25 史密夫和内修公司 稳定的嗜热菌蛋白酶水凝胶
CN105050629B (zh) 2013-03-15 2018-09-25 史密夫和内修公司 用于递送活性剂的可溶解的形成凝胶的膜
ES2869024T3 (es) 2013-11-08 2021-10-22 Hollister Inc Catéteres oleófilos lubricados
EP2889030A1 (de) * 2013-12-30 2015-07-01 Uluru Inc. Steuerung der Erosionsraten von mukoadhäsiven Vorrichtungen mit Lieferung von Wirkstoffen und anderen Verbindungen und Bereitstellung erhöhter und unterschiedlicher therapeutischer Blutwerte
JP2015232086A (ja) * 2014-06-10 2015-12-24 大日本印刷株式会社 貼付用シート
CN104436283B (zh) * 2014-11-10 2016-05-25 苏州蔻美新材料有限公司 一种医用胶原膜材料及其制备方法
WO2017085262A1 (en) * 2015-11-19 2017-05-26 Dermtreat Aps A pharmaceutical film composition having improved residence time on the application site
CN122182527A (zh) 2016-05-05 2026-06-12 阿奎斯蒂弗医疗股份有限公司 增强递送的肾上腺素组合物
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
KR102412540B1 (ko) * 2016-11-18 2022-06-23 파나소닉 아이피 매니지먼트 가부시키가이샤 생체 부착용 막 및 그 제조 방법
EP3691610A1 (de) 2017-10-07 2020-08-12 Zim Laboratories Limited Verfahren zur herstellung von zwei-/mehrschichtfolien, daraus hergestellte mehrschichtfolien und vorrichtung zur herstellung solcher mehrschichtfolien
EP3542788A1 (de) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topische zusammensetzung enthaltend calcipotriol und betamethason dipropionat
EP4378527A3 (de) * 2019-12-20 2024-09-11 LTS Lohmann Therapie-Systeme AG Transmukosales therapeutisches system mit agomelatin
ES3003263T3 (en) * 2019-12-20 2025-03-10 Lts Lohmann Therapie Systeme Ag Transmucosal therapeutic system containing agomelatine
US12629380B2 (en) 2021-08-25 2026-05-19 Swipp Ab Oral film unit dosage form
WO2023076281A1 (en) 2021-10-25 2023-05-04 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment
US12691080B2 (en) * 2024-05-21 2026-07-28 Arx, Llc Fenretinide formulations, systems incorporating same, and methods for their use

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5770816A (en) * 1980-10-17 1982-05-01 Ono Pharmaceut Co Ltd Multilayered film preparation of prostagladin of prolonged action
CH653550A5 (de) * 1981-10-20 1986-01-15 Sandoz Ag Pharmazeutische zusammensetzung zur verzoegerten freigabe eines medikamentes im mundbereich.
JPS60116630A (ja) * 1983-11-29 1985-06-24 Nitto Electric Ind Co Ltd 口腔内製剤
JPS61280423A (ja) * 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
JPS61290423A (ja) * 1985-06-18 1986-12-20 Mitsubishi Electric Corp 液晶表示素子およびその製造方法
JPH0653659B2 (ja) * 1985-07-22 1994-07-20 ニチバン株式会社 粘膜付着製剤
JPS6256420A (ja) * 1985-09-05 1987-03-12 Teijin Ltd フイルム状付着性製剤
JPH07553B2 (ja) * 1985-12-09 1995-01-11 佐藤製薬株式会社 フイルム状製剤
JPH0729915B2 (ja) * 1986-02-01 1995-04-05 帝國製薬株式会社 シ−ト状口腔内貼付剤
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
CH668187A5 (de) * 1986-08-07 1988-12-15 Ciba Geigy Ag Therapeutisches system mit systemischer wirkung.
JPH0794384B2 (ja) * 1986-09-01 1995-10-11 帝国製薬株式会社 徐放性口腔内用製剤
JPS63310818A (ja) * 1987-06-12 1988-12-19 Sato Seiyaku Kk シ−ト状口腔粘膜付着製剤
JPS6471812A (en) * 1987-09-11 1989-03-16 Sekisui Chemical Co Ltd Medical application agent
JP2635336B2 (ja) * 1987-09-30 1997-07-30 帝國製薬株式会社 徐放性口腔内用製剤
JP2685055B2 (ja) * 1988-03-08 1997-12-03 帝國製薬株式会社 シコン含有口腔粘膜貼付剤
JP2656338B2 (ja) * 1989-01-31 1997-09-24 日東電工株式会社 口腔粘膜貼付製剤
JP2879695B2 (ja) * 1990-02-22 1999-04-05 日本曹達株式会社 口腔内粘膜付着性フィルム製剤
JP2930374B2 (ja) * 1990-06-28 1999-08-03 東亜医薬品工業株式会社 口腔内貼着型膜製剤
US5700478A (en) * 1993-08-19 1997-12-23 Cygnus, Inc. Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity
JP2791317B2 (ja) * 1995-12-26 1998-08-27 株式会社三和化学研究所 多層フィルム製剤
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces

Also Published As

Publication number Publication date
WO1999055312A3 (en) 2000-01-13
AU3967899A (en) 1999-11-16
JP2005325140A (ja) 2005-11-24
WO1999055312A2 (en) 1999-11-04
CA2329128A1 (en) 1999-11-04
ES2237104T3 (es) 2005-07-16
US20080254105A1 (en) 2008-10-16
PT1079813E (pt) 2005-05-31
CA2329128C (en) 2008-03-18
JP2010265319A (ja) 2010-11-25
AU746339B2 (en) 2002-04-18
EP1079813A2 (de) 2001-03-07
EP1079813B1 (de) 2005-02-09
DK1079813T3 (da) 2005-06-06
JP2002512950A (ja) 2002-05-08
DE69923675D1 (de) 2005-03-17
DE69923675T2 (de) 2006-05-11
JP4619894B2 (ja) 2011-01-26

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