ATE288744T1 - Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut - Google Patents

Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut

Info

Publication number: ATE288744T1
Authority: AT; Austria
Prior art keywords: skin; replacement therapy; topical use; hormone replacement; medicinal formulations
Prior art date: 1997-10-16

Application number

AT98952067T

Other languages

English (en)

Inventor

Carlos M Samour

Scott F Krauser

Robert J Gyurik

Original Assignee

Macrochem Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-16

Filing date

1998-10-02

Publication date

2005-02-15

1998-10-02 Application filed by Macrochem Corp filed Critical Macrochem Corp

2005-02-15 Application granted granted Critical

2005-02-15 Publication of ATE288744T1 publication Critical patent/ATE288744T1/de

Links

239000000203 mixture Substances 0.000 title abstract 2
230000000699 topical effect Effects 0.000 title abstract 2
238000002657 hormone replacement therapy Methods 0.000 title 1
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
230000001476 alcoholic effect Effects 0.000 abstract 2
230000035515 penetration Effects 0.000 abstract 2
VDFVNEFVBPFDSB-UHFFFAOYSA-N 1,3-dioxane Chemical compound C1COCOC1 VDFVNEFVBPFDSB-UHFFFAOYSA-N 0.000 abstract 1
VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 abstract 1
QPILHXCDZYWYLQ-UHFFFAOYSA-N 2-nonyl-1,3-dioxolane Chemical compound CCCCCCCCCC1OCCO1 QPILHXCDZYWYLQ-UHFFFAOYSA-N 0.000 abstract 1
DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000002708 enhancing effect Effects 0.000 abstract 1
229960005309 estradiol Drugs 0.000 abstract 1
229930182833 estradiol Natural products 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1
239000000499 gel Substances 0.000 abstract 1
229940088597 hormone Drugs 0.000 abstract 1
239000005556 hormone Substances 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
239000000186 progesterone Substances 0.000 abstract 1
229960003387 progesterone Drugs 0.000 abstract 1
229960003604 testosterone Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Prostheses (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

AT98952067T 1997-10-16 1998-10-02 Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut ATE288744T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/953,014 US5968919A (en)	1997-10-16	1997-10-16	Hormone replacement therapy drug formulations for topical application to the skin
PCT/US1998/020895 WO1999020257A1 (en)	1997-10-16	1998-10-02	Hormone replacement therapy drug formulations for topical application to the skin

Publications (1)

Publication Number	Publication Date
ATE288744T1 true ATE288744T1 (de)	2005-02-15

Family

ID=25493463

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98952067T ATE288744T1 (de)	1997-10-16	1998-10-02	Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut

Country Status (10)

Country	Link
US (1)	US5968919A (de)
EP (1)	EP0971705B1 (de)
JP (1)	JP2001505930A (de)
AT (1)	ATE288744T1 (de)
CA (1)	CA2260185C (de)
DE (1)	DE69828958T2 (de)
DK (1)	DK0971705T3 (de)
ES (1)	ES2238094T3 (de)
PT (1)	PT971705E (de)
WO (1)	WO1999020257A1 (de)

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1997
- 1997-10-16 US US08/953,014 patent/US5968919A/en not_active Expired - Fee Related
1998
- 1998-10-02 EP EP98952067A patent/EP0971705B1/de not_active Expired - Lifetime
- 1998-10-02 AT AT98952067T patent/ATE288744T1/de not_active IP Right Cessation
- 1998-10-02 DK DK98952067T patent/DK0971705T3/da active
- 1998-10-02 ES ES98952067T patent/ES2238094T3/es not_active Expired - Lifetime
- 1998-10-02 CA CA002260185A patent/CA2260185C/en not_active Expired - Fee Related
- 1998-10-02 PT PT98952067T patent/PT971705E/pt unknown
- 1998-10-02 DE DE69828958T patent/DE69828958T2/de not_active Expired - Fee Related
- 1998-10-02 JP JP52411099A patent/JP2001505930A/ja not_active Ceased
- 1998-10-02 WO PCT/US1998/020895 patent/WO1999020257A1/en not_active Ceased

Also Published As

Publication number	Publication date
PT971705E (pt)	2005-06-30
JP2001505930A (ja)	2001-05-08
CA2260185C (en)	2008-12-23
DK0971705T3 (da)	2005-06-13
US5968919A (en)	1999-10-19
EP0971705B1 (de)	2005-02-09
WO1999020257A1 (en)	1999-04-29
ES2238094T3 (es)	2005-08-16
DE69828958D1 (de)	2005-03-17
EP0971705A1 (de)	2000-01-19
CA2260185A1 (en)	1999-04-17
DE69828958T2 (de)	2006-01-19
EP0971705A4 (de)	2001-01-31

Legal Events

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2005-10-15

UEP

Publication of translation of european patent specification

Ref document number: 0971705

Country of ref document: EP

2010-07-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE288744T1 (de)	2005-02-15	Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut
DE69919863D1 (de)	2004-10-07	Stabilgelmischung in form einer mischung eines öligen gels und eines wässrigen gels
BR0113670A (pt)	2004-11-09	Composição farmacêutica e método para tratar hipogonadismo
DK0742714T3 (da)	2001-04-30	Flydende farmaceutiske præparater omfattende thyroideahormoner
ES2160623T3 (es)	2001-11-16	Composiciones farmaceuticas mejoradas para la penetracion en la piel de piroxicam.
ES2106029T3 (es)	1997-11-01	Composiciones que mejoran la penetracion a traves de la piel.
PT748190E (pt)	2003-12-31	Metodos e formulacoes para uso no tratamento de disturbios ginecologicos benignos
ES2132216T3 (es)	1999-08-16	Nuevos derivados de amidinas, su preparacion y utilizacion como medicamentos con efecto antagonista de ltb4.
DE59808186D1 (de)	2003-06-05	Transdermales therapeutisches system zur abgabe von hormonen
DE69724647D1 (de)	2003-10-09	Acyclovirhaltige antiherpesarzneistift zur topischen anwendung
ATE165521T1 (de)	1998-05-15	Verminderung der hautreizung während einer iontophoretischen abgabe von medikamenten
ES2157307T3 (es)	2001-08-16	Composicion topica que contiene un antagonista de sustancia p.
AR002944A1 (es)	1998-05-27	Uso de una composicion de gel acuosa que contiene una o mas drogas que son eficaces para tratar hemorroides para la preparacion de un medicamento y dicha composicion de gel acuosa
EA200201000A1 (ru)	2003-02-27	Гормон-заместительная терапия
MXPA02012075A (es)	2004-08-19	Composicion para mediar el dolor y aparato y metodo para utilizarla.
EE03105B1 (et)	1998-08-17	Farmakoloogilist ioniseeruvat toimeainet sisaldavad ravimvormid ja nende valmistamise protsess
ES2172937T3 (es)	2002-10-01	21-hidroxi-6,19-oxidoprogesterona(21oh-6op) como medicamento para tratar el exceso de glucocorticoides.
AU2284001A (en)	2001-07-09	Substituted aminoalkylamide derivatives as antagonists of follicle stimulating hormone
AR004052A1 (es)	1998-09-30	Una composición cosmética o farmacéutica que comprende un agonista beta-adrenergico
ES2026754A6 (es)	1992-05-01	Procedimiento de obtencion de una composicion para el tratamiento cosmetico de la piel y del cuerpo.
ATE353224T1 (de)	2007-02-15	Abgabeeinrichtung für eine zusammensetzung einer pharmazeutisch wirksamen substanz
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DE59301120D1 (de)	1996-01-18	Zubereitung zur topischen anwendung.