ATE288908T1 - Monozyclische n-heterozyclische thiosäure derivate als antikoagulans - Google Patents

Monozyclische n-heterozyclische thiosäure derivate als antikoagulans

Info

Publication number
ATE288908T1
ATE288908T1 AT97944891T AT97944891T ATE288908T1 AT E288908 T1 ATE288908 T1 AT E288908T1 AT 97944891 T AT97944891 T AT 97944891T AT 97944891 T AT97944891 T AT 97944891T AT E288908 T1 ATE288908 T1 AT E288908T1
Authority
AT
Austria
Prior art keywords
monocyclic
anticoagulant
heterocyclic
derivatives
thioacid
Prior art date
Application number
AT97944891T
Other languages
English (en)
Inventor
Monica J Kochanny
Michael M Morrissey
Howard P Ng
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of ATE288908T1 publication Critical patent/ATE288908T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97944891T 1996-10-09 1997-09-24 Monozyclische n-heterozyclische thiosäure derivate als antikoagulans ATE288908T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/731,128 US6004985A (en) 1996-10-09 1996-10-09 Thio acid derived monocylic N-heterocyclics as anticoagulants
PCT/EP1997/005231 WO1998015547A1 (en) 1996-10-09 1997-09-24 Thio acid derived monocyclic n-heterocyclics as anticoagulants

Publications (1)

Publication Number Publication Date
ATE288908T1 true ATE288908T1 (de) 2005-02-15

Family

ID=24938188

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97944891T ATE288908T1 (de) 1996-10-09 1997-09-24 Monozyclische n-heterozyclische thiosäure derivate als antikoagulans

Country Status (21)

Country Link
US (6) US6004985A (de)
EP (1) EP0934310B1 (de)
JP (1) JP3768244B2 (de)
KR (1) KR20000048966A (de)
CN (1) CN1111159C (de)
AT (1) ATE288908T1 (de)
AU (1) AU730060B2 (de)
CA (1) CA2268172A1 (de)
CZ (1) CZ122799A3 (de)
DE (1) DE69732490T2 (de)
DK (1) DK0934310T3 (de)
ES (1) ES2236828T3 (de)
HK (1) HK1020958A1 (de)
HU (1) HUP9904180A3 (de)
IL (1) IL129056A0 (de)
NO (1) NO991594L (de)
NZ (1) NZ334758A (de)
PL (1) PL332602A1 (de)
PT (1) PT934310E (de)
SK (1) SK46499A3 (de)
WO (1) WO1998015547A1 (de)

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US6140351A (en) * 1997-12-19 2000-10-31 Berlex Laboratories, Inc. Ortho-anthranilamide derivatives as anti-coagulants
NZ503809A (en) 1997-12-19 2002-04-26 Schering Ag Ortho-anthranilamide derivatives as anti-coagulants
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US6960705B2 (en) 1998-10-05 2005-11-01 Eden Bioscience Corporation Nucleic acid encoding a hypersensitive response elicitor from Xanthomonas campestris
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IL166241A0 (en) 2002-07-29 2006-01-15 Rigel Pharmaceuticals Inc Method of treating or preventing autoimmune diseases with 2,4-pyrimidinedinediamine compounds
US7419984B2 (en) * 2002-10-17 2008-09-02 Cell Therapeutics, Inc. Pyrimidines and uses thereof
KR20040042071A (ko) * 2002-11-12 2004-05-20 박영민 인터넷 홈페이지를 활용한 경조사 자동알림 및 게시판 자동등록 방법
CN100513398C (zh) 2002-12-03 2009-07-15 Axys药物公司 作为因子viia抑制剂的2-(2-羟基联苯-3-基)-1h-苯并咪唑-5-甲脒衍生物
US6875781B2 (en) * 2003-04-04 2005-04-05 Cell Therapeutics, Inc. Pyridines and uses thereof
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ATE540035T1 (de) 2004-11-24 2012-01-15 Rigel Pharmaceuticals Inc Spiro-2,4-pyrimidindiamin-verbindungen und ihre verwendungen
US7449458B2 (en) 2005-01-19 2008-11-11 Rigel Pharmaceuticals, Inc. Prodrugs of 2,4-pyrimidinediamine compounds and their uses
JP2008540436A (ja) * 2005-05-03 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド Ｊａｋキナーゼインヒビターおよびそれらの使用
US20070015834A1 (en) * 2005-07-18 2007-01-18 Moshe Flashner-Barak Formulations of fenofibrate containing PEG/Poloxamer
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
US8063058B2 (en) 2008-04-16 2011-11-22 Portola Pharmaceuticals, Inc. Inhibitors of syk and JAK protein kinases
JP2011523646A (ja) 2008-05-21 2011-08-18 アリアド・ファーマシューティカルズ・インコーポレイテッド キナーゼ阻害剤としてのリン誘導体
US9273077B2 (en) 2008-05-21 2016-03-01 Ariad Pharmaceuticals, Inc. Phosphorus derivatives as kinase inhibitors
AU2012250517B2 (en) 2011-05-04 2016-05-19 Takeda Pharmaceutical Company Limited Compounds for inhibiting cell proliferation in EGFR-driven cancers
EP2782579B1 (de) 2011-11-23 2019-01-02 Portola Pharmaceuticals, Inc. Pyrazinkinaseinhibitoren
JP6469567B2 (ja) 2012-05-05 2019-02-13 アリアド・ファーマシューティカルズ・インコーポレイテッド Ｅｇｆｒ発動性がんの細胞増殖阻害用化合物
US9611283B1 (en) 2013-04-10 2017-04-04 Ariad Pharmaceuticals, Inc. Methods for inhibiting cell proliferation in ALK-driven cancers
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Also Published As

Publication number Publication date
CZ122799A3 (cs) 1999-09-15
SK46499A3 (en) 2000-04-10
PL332602A1 (en) 1999-09-27
NZ334758A (en) 2000-11-24
NO991594L (no) 1999-06-08
US6221886B1 (en) 2001-04-24
US6004985A (en) 1999-12-21
CN1111159C (zh) 2003-06-11
AU730060B2 (en) 2001-02-22
EP0934310A1 (de) 1999-08-11
DE69732490T2 (de) 2006-04-27
HK1020958A1 (en) 2004-03-19
US6162807A (en) 2000-12-19
KR20000048966A (ko) 2000-07-25
JP3768244B2 (ja) 2006-04-19
US6150382A (en) 2000-11-21
CN1233247A (zh) 1999-10-27
IL129056A0 (en) 2000-02-17
CA2268172A1 (en) 1998-04-16
HUP9904180A3 (en) 2000-11-28
PT934310E (pt) 2005-06-30
US6166014A (en) 2000-12-26
HUP9904180A2 (hu) 2000-09-28
US6034084A (en) 2000-03-07
DK0934310T3 (da) 2005-05-30
NO991594D0 (no) 1999-03-31
WO1998015547A1 (en) 1998-04-16
DE69732490D1 (en) 2005-03-17
EP0934310B1 (de) 2005-02-09
AU4624097A (en) 1998-05-05
ES2236828T3 (es) 2005-07-16
JP2001501632A (ja) 2001-02-06

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