ATE288917T1 - Verfahren zur herstellung von morphine-6- glucuronide und derivate unter verwendung von haloglucuronatester - Google Patents

Verfahren zur herstellung von morphine-6- glucuronide und derivate unter verwendung von haloglucuronatester

Info

Publication number
ATE288917T1
ATE288917T1 AT00938910T AT00938910T ATE288917T1 AT E288917 T1 ATE288917 T1 AT E288917T1 AT 00938910 T AT00938910 T AT 00938910T AT 00938910 T AT00938910 T AT 00938910T AT E288917 T1 ATE288917 T1 AT E288917T1
Authority
AT
Austria
Prior art keywords
haloglucuronate
esters
morphine
glucuronides
derivatives
Prior art date
Application number
AT00938910T
Other languages
English (en)
Inventor
Feodor Scheinmann
Andrew Valentine Stachulski
John Ferguson
Jane Louise Law
Original Assignee
Ufc Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ufc Ltd filed Critical Ufc Ltd
Application granted granted Critical
Publication of ATE288917T1 publication Critical patent/ATE288917T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT00938910T 1999-06-21 2000-06-20 Verfahren zur herstellung von morphine-6- glucuronide und derivate unter verwendung von haloglucuronatester ATE288917T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9914382.8A GB9914382D0 (en) 1999-06-21 1999-06-21 New process for the manufacture of morphine-6-glucuronide and its analogues and also to a manufacture of new intermediaries
PCT/GB2000/002232 WO2000078764A1 (en) 1999-06-21 2000-06-20 Process for making morphine-6-glucuronide and its analogues using haloglucuronate ester intermediates

Publications (1)

Publication Number Publication Date
ATE288917T1 true ATE288917T1 (de) 2005-02-15

Family

ID=10855704

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00938910T ATE288917T1 (de) 1999-06-21 2000-06-20 Verfahren zur herstellung von morphine-6- glucuronide und derivate unter verwendung von haloglucuronatester

Country Status (9)

Country Link
US (1) US6642366B1 (de)
EP (1) EP1200441B1 (de)
JP (1) JP2003502427A (de)
AT (1) ATE288917T1 (de)
AU (1) AU5413400A (de)
CA (1) CA2375274A1 (de)
DE (1) DE60018070T2 (de)
GB (1) GB9914382D0 (de)
WO (1) WO2000078764A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7982167B2 (en) 2005-12-08 2011-07-19 Graphic Packaging International, Inc. Microwave food heating package with removable portion
FR2939436B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Synthese de morphine-6-glucuronide ou de l'un de ses derives
EP2717057A1 (de) * 2012-10-04 2014-04-09 Cisbio Bioassays Morphin-6-glucuronid-Derivate, Immunogene und Immunassay

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0373118A3 (de) * 1988-12-07 1991-10-16 Ciba-Geigy Ag Verfahren zur Herstellung von geschützten Mono- und Oligozuckerhalogeniden
GB9325065D0 (en) * 1993-12-07 1994-02-02 Salford Ultrafine Chem & Res An enzymatic process for making morphine-6-glucuronide or substituted morphine-6-glucuronide
GB9116909D0 (en) * 1991-08-06 1991-09-18 Salford Ultrafine Chem & Res Morphine derivatives
US5908927A (en) * 1996-05-22 1999-06-01 High Standard Products Corporation Synthesis of deuterated opiate glucuronides
DE69815336T2 (de) * 1997-04-14 2004-05-06 Ufc Ltd. Morphin-derivate
HUP0100841A3 (en) * 1998-02-02 2003-03-28 Cenes Ltd Cambridge Glycosidation of 4,5-epoxymorphinan-6-ols
ATE225363T1 (de) * 1998-06-06 2002-10-15 Cenes Ltd Synthese von morphin-6-glucuronid

Also Published As

Publication number Publication date
EP1200441B1 (de) 2005-02-09
GB9914382D0 (en) 1999-08-18
DE60018070T2 (de) 2005-12-29
JP2003502427A (ja) 2003-01-21
US6642366B1 (en) 2003-11-04
AU5413400A (en) 2001-01-09
EP1200441A1 (de) 2002-05-02
DE60018070D1 (de) 2005-03-17
CA2375274A1 (en) 2000-12-28
WO2000078764A1 (en) 2000-12-28

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Legal Events

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