ATE469149T1 - Verfahren zur herstellung von cabergolin - Google Patents

Verfahren zur herstellung von cabergolin

Info

Publication number: ATE469149T1
Authority: AT; Austria
Prior art keywords: cabergoline; xix; xviii; xvii; xvi
Prior art date: 2004-03-04

Application number

AT05718154T

Other languages

English (en)

Inventor

Janos Galambos

Laszlo Czibula

Ferenc Sebak

Sandorne Balint

Ferencne Kassai

SZENDREI Gyoergyi IGNACZNE

Dam Demeter

Original Assignee

Richter Gedeon Nyrt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-03-04

Filing date

2005-03-02

Publication date

2010-06-15

2005-03-02 Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt

2010-06-15 Application granted granted Critical

2010-06-15 Publication of ATE469149T1 publication Critical patent/ATE469149T1/de

Links

KORNTPPJEAJQIU-KJXAQDMKSA-N Cabaser Chemical compound C1=CC([C@H]2C[C@H](CN(CC=C)[C@@H]2C2)C(=O)N(CCCN(C)C)C(=O)NCC)=C3C2=CNC3=C1 KORNTPPJEAJQIU-KJXAQDMKSA-N 0.000 title abstract 3
229960004596 cabergoline Drugs 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title abstract 3
239000000543 intermediate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT05718154T 2004-03-04 2005-03-02 Verfahren zur herstellung von cabergolin ATE469149T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU0400517A HUP0400517A3 (en)	2004-03-04	2004-03-04	Process for producing cabergoline
PCT/HU2005/000022 WO2005085243A2 (en)	2004-03-04	2005-03-02	Process for the preparation of cabergoline

Publications (1)

Publication Number	Publication Date
ATE469149T1 true ATE469149T1 (de)	2010-06-15

Family

ID=89982034

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05718154T ATE469149T1 (de)	2004-03-04	2005-03-02	Verfahren zur herstellung von cabergolin

Country Status (7)

Country	Link
US (1)	US7858791B2 (de)
EP (1)	EP1720869B1 (de)
AT (1)	ATE469149T1 (de)
DE (1)	DE602005021461D1 (de)
EA (1)	EA010689B1 (de)
HU (1)	HUP0400517A3 (de)
WO (1)	WO2005085243A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2004238833A1 (en) *	2003-05-08	2004-11-25	Ivax Pharmaceuticals S.R.O.	Polymorphs of cabergoline
EP1925616A1 (de) *	2006-10-26	2008-05-28	LEK Pharmaceuticals D.D.	Verfahren zur Herstellung kristalliner Formen des Cabergolins via stabile Solvate des Cabergolins
WO2008104956A2 (en) *	2007-02-28	2008-09-04	Ranbaxy Laboratories Limited	Process for the preparation of amorphous cabergoline
EP2083008A1 (de) *	2007-12-07	2009-07-29	Axxonis Pharma AG	Ergolin-Derivate als selektive Radikalfänger für Neuronen
CA2936749C (en) *	2010-06-11	2019-07-09	Rhodes Technologies	Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
CA2876321A1 (en) *	2012-06-22	2013-12-27	Map Pharmaceuticals, Inc.	Novel cabergoline derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9205439D0 (en) *	1992-03-12	1992-04-22	Erba Carlo Spa	Process for the synthesis of ergoline derivatives
JP2004525187A (ja) *	2001-04-16	2004-08-19	フイネテク・リミテツド	カベルゴリンおよび関連化合物の製造のための方法および中間体
US6696568B2 (en) *	2001-04-16	2004-02-24	Finetech Ltd.	Process and intermediates for production of cabergoline and related compounds

2004
- 2004-03-04 HU HU0400517A patent/HUP0400517A3/hu unknown
2005
- 2005-03-02 AT AT05718154T patent/ATE469149T1/de not_active IP Right Cessation
- 2005-03-02 WO PCT/HU2005/000022 patent/WO2005085243A2/en not_active Ceased
- 2005-03-02 DE DE602005021461T patent/DE602005021461D1/de not_active Expired - Lifetime
- 2005-03-02 EA EA200601628A patent/EA010689B1/ru not_active IP Right Cessation
- 2005-03-02 US US10/591,202 patent/US7858791B2/en not_active Expired - Fee Related
- 2005-03-02 EP EP05718154A patent/EP1720869B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
HUP0400517A2 (hu)	2005-11-28
HU0400517D0 (en)	2004-05-28
US20070293677A1 (en)	2007-12-20
EP1720869B1 (de)	2010-05-26
WO2005085243A2 (en)	2005-09-15
EA010689B1 (ru)	2008-10-30
HUP0400517A3 (en)	2006-05-29
EP1720869A2 (de)	2006-11-15
WO2005085243A3 (en)	2006-04-06
US7858791B2 (en)	2010-12-28
DE602005021461D1 (de)	2010-07-08
EA200601628A1 (ru)	2007-02-27

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Legal Events

Date	Code	Title	Description
2010-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties