ATE289510T1 - Sulfonylpyridazinone derivate zur behandlung von ischämischem gewebeschaden - Google Patents
Sulfonylpyridazinone derivate zur behandlung von ischämischem gewebeschadenInfo
- Publication number
- ATE289510T1 ATE289510T1 AT02253605T AT02253605T ATE289510T1 AT E289510 T1 ATE289510 T1 AT E289510T1 AT 02253605 T AT02253605 T AT 02253605T AT 02253605 T AT02253605 T AT 02253605T AT E289510 T1 ATE289510 T1 AT E289510T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- tissue damage
- sulfonylpyridazinone
- derivatives
- ischemic tissue
- Prior art date
Links
- 230000000451 tissue damage Effects 0.000 title abstract 2
- 231100000827 tissue damage Toxicity 0.000 title abstract 2
- UUAVJCDYOHIIQW-UHFFFAOYSA-N 4-sulfonylpyridazin-3-one Chemical class O=C1N=NC=CC1=S(=O)=O UUAVJCDYOHIIQW-UHFFFAOYSA-N 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29339301P | 2001-05-24 | 2001-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE289510T1 true ATE289510T1 (de) | 2005-03-15 |
Family
ID=23128899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02253605T ATE289510T1 (de) | 2001-05-24 | 2002-05-22 | Sulfonylpyridazinone derivate zur behandlung von ischämischem gewebeschaden |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6872722B2 (de) |
| EP (1) | EP1260224B1 (de) |
| JP (1) | JP2002370984A (de) |
| KR (1) | KR20020090321A (de) |
| CN (1) | CN1390547A (de) |
| AT (1) | ATE289510T1 (de) |
| AU (1) | AU761191B2 (de) |
| CA (1) | CA2387007A1 (de) |
| CZ (1) | CZ20021782A3 (de) |
| DE (1) | DE60203026T2 (de) |
| ES (1) | ES2236447T3 (de) |
| HU (1) | HUP0201738A3 (de) |
| PL (1) | PL354128A1 (de) |
| SK (1) | SK7332002A3 (de) |
| ZA (1) | ZA200203985B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2240657T3 (es) * | 2001-02-28 | 2005-10-16 | Pfizer Products Inc. | Compuestos de sulfonilpiridazinona utiles como inhibidores de aldosa reductasa. |
| CN101325952B (zh) * | 2005-12-16 | 2012-02-08 | 株式会社三和化学研究所 | 用于急性肾衰竭的预防和治疗剂 |
| CA2642933A1 (en) * | 2006-02-20 | 2007-08-30 | Sanwa Kagaku Kenkyusho Co., Ltd. | Prophylactic or therapeutic agent for cerebral ischemia or cerebral ischemic reperfusion injury in stroke |
| WO2022197487A1 (en) | 2021-03-18 | 2022-09-22 | Banavara MYLARI | Combination of aldose reductase inhibitors and probenecid for the treatment of diabetic complications |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE47592B1 (en) | 1977-12-29 | 1984-05-02 | Ici Ltd | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof,and process for their manufacture |
| US4939140A (en) | 1985-11-07 | 1990-07-03 | Pfizer Inc. | Heterocyclic oxophthalazinyl acetic acids |
| JPH01258671A (ja) * | 1987-12-01 | 1989-10-16 | Morishita Pharmaceut Co Ltd | ５−（１ｈ−イミダゾール−１−イル）−３（２ｈ）−ピリダジノン誘導体 |
| US4996204A (en) | 1989-05-11 | 1991-02-26 | Pfizer Inc. | Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors |
| CZ387092A3 (en) * | 1991-03-28 | 1994-02-16 | Pfizer | Pyridazinoacetic acids, their derivatives, process of their preparation and use |
| US5834466A (en) | 1994-12-22 | 1998-11-10 | The Regents Of The University Of California | Method for protecting of heart by limiting metabolic and ionic abnormalities developed during ischemia, following ischemia or resulting from ischemia |
| US5670504A (en) * | 1995-02-23 | 1997-09-23 | Merck & Co. Inc. | 2,6-diaryl pyridazinones with immunosuppressant activity |
| US5506228A (en) * | 1995-02-23 | 1996-04-09 | Merck & Co., Inc. | 2,6-diaryl pyridazinones with immunosuppressant activity |
| EP2017266A1 (de) * | 1997-11-19 | 2009-01-21 | Kowa Co., Ltd. | Pyridazinderivate und diese als aktiven Bestandteil enthaltende Medikamente |
| TWI241295B (en) * | 1998-03-02 | 2005-10-11 | Kowa Co | Pyridazine derivative and medicine containing the same as effect component |
| JP2000247959A (ja) * | 1999-02-26 | 2000-09-12 | Kowa Co | ピリダジン−３−オン誘導体及びこれを含有する医薬 |
| ES2240657T3 (es) * | 2001-02-28 | 2005-10-16 | Pfizer Products Inc. | Compuestos de sulfonilpiridazinona utiles como inhibidores de aldosa reductasa. |
| ATE348100T1 (de) * | 2001-03-30 | 2007-01-15 | Pfizer Prod Inc | Zwischenprodukten für die herstellung von pyridazinon aldose reductase inhibitoren. |
-
2002
- 2002-05-16 AU AU40685/02A patent/AU761191B2/en not_active Ceased
- 2002-05-17 CA CA002387007A patent/CA2387007A1/en not_active Abandoned
- 2002-05-20 ZA ZA200203985A patent/ZA200203985B/xx unknown
- 2002-05-20 JP JP2002144503A patent/JP2002370984A/ja active Pending
- 2002-05-22 EP EP02253605A patent/EP1260224B1/de not_active Expired - Lifetime
- 2002-05-22 CZ CZ20021782A patent/CZ20021782A3/cs unknown
- 2002-05-22 AT AT02253605T patent/ATE289510T1/de not_active IP Right Cessation
- 2002-05-22 DE DE60203026T patent/DE60203026T2/de not_active Expired - Fee Related
- 2002-05-22 ES ES02253605T patent/ES2236447T3/es not_active Expired - Lifetime
- 2002-05-23 HU HU0201738A patent/HUP0201738A3/hu unknown
- 2002-05-23 KR KR1020020028665A patent/KR20020090321A/ko not_active Ceased
- 2002-05-23 US US10/154,694 patent/US6872722B2/en not_active Expired - Fee Related
- 2002-05-24 PL PL02354128A patent/PL354128A1/xx not_active Application Discontinuation
- 2002-05-24 CN CN02120397A patent/CN1390547A/zh active Pending
- 2002-05-24 SK SK733-2002A patent/SK7332002A3/sk unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU761191B2 (en) | 2003-05-29 |
| DE60203026T2 (de) | 2006-05-04 |
| AU4068502A (en) | 2002-11-28 |
| SK7332002A3 (en) | 2003-05-02 |
| HUP0201738A2 (hu) | 2003-02-28 |
| PL354128A1 (en) | 2002-12-02 |
| EP1260224B1 (de) | 2005-02-23 |
| KR20020090321A (ko) | 2002-12-02 |
| CN1390547A (zh) | 2003-01-15 |
| US20030008871A1 (en) | 2003-01-09 |
| CA2387007A1 (en) | 2002-11-24 |
| HUP0201738A3 (en) | 2003-11-28 |
| CZ20021782A3 (cs) | 2003-03-12 |
| EP1260224A1 (de) | 2002-11-27 |
| ZA200203985B (en) | 2003-11-20 |
| HU0201738D0 (de) | 2002-07-29 |
| JP2002370984A (ja) | 2002-12-24 |
| ES2236447T3 (es) | 2005-07-16 |
| DE60203026D1 (de) | 2005-03-31 |
| US6872722B2 (en) | 2005-03-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |