ATE289609T1 - Makrolid-lhrh-antagonisten - Google Patents

Makrolid-lhrh-antagonisten

Info

Publication number
ATE289609T1
ATE289609T1 AT99912259T AT99912259T ATE289609T1 AT E289609 T1 ATE289609 T1 AT E289609T1 AT 99912259 T AT99912259 T AT 99912259T AT 99912259 T AT99912259 T AT 99912259T AT E289609 T1 ATE289609 T1 AT E289609T1
Authority
AT
Austria
Prior art keywords
lhrh antagonists
macrolide
compounds
disclosed
antagonists
Prior art date
Application number
AT99912259T
Other languages
English (en)
Inventor
Daryl R Sauer
Fortuna Haviv
John Randolph
Nicholas A Mort
Christopher R Dalton
Milan Bruncko
Michele A Kaminski
Bradley W Crawford
Lisa Marie Frey
Jonathon Greer
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE289609T1 publication Critical patent/ATE289609T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99912259T 1998-03-27 1999-03-11 Makrolid-lhrh-antagonisten ATE289609T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/049,963 US5955440A (en) 1998-03-27 1998-03-27 Macrolide LHRH antagonists
PCT/US1999/004658 WO1999050275A2 (en) 1998-03-27 1999-03-11 Macrolide lhrh antagonists

Publications (1)

Publication Number Publication Date
ATE289609T1 true ATE289609T1 (de) 2005-03-15

Family

ID=21962689

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99912259T ATE289609T1 (de) 1998-03-27 1999-03-11 Makrolid-lhrh-antagonisten

Country Status (20)

Country Link
US (1) US5955440A (de)
EP (1) EP1066304B1 (de)
JP (1) JP2002509937A (de)
KR (1) KR20010034694A (de)
CN (1) CN1307584A (de)
AT (1) ATE289609T1 (de)
AU (1) AU3067499A (de)
BG (1) BG104844A (de)
BR (1) BR9909080A (de)
CA (1) CA2325521A1 (de)
DE (1) DE69923835T2 (de)
ES (1) ES2238828T3 (de)
HU (1) HUP0102011A3 (de)
IL (1) IL138219A0 (de)
NO (1) NO20004860L (de)
PL (1) PL348242A1 (de)
PT (1) PT1066304E (de)
SK (1) SK13972000A3 (de)
TR (1) TR200002767T2 (de)
WO (1) WO1999050275A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
ATE432691T1 (de) * 2000-03-28 2009-06-15 Sandoz Ag Geschmackmaskierte granulierte teilchen
EP1146051A3 (de) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A-Derivate
US7091196B2 (en) * 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
AU2004217919A1 (en) * 2003-03-05 2004-09-16 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using the same
WO2005042554A1 (en) * 2003-10-30 2005-05-12 Rib-X Pharmaceuticals, Inc. Bifunctional macrolide heterocyclic compounds and methods of making and using the same
JP2007512256A (ja) * 2003-11-18 2007-05-17 リブ−エックス ファーマシューティカルズ，インコーポレイテッド 二官能性マクロライド複素環化合物ならびにこれらを製造する方法およびこれらを使用する方法
EP2716647A3 (de) * 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung
SI1836211T1 (sl) * 2004-12-21 2010-04-30 Pfizer Prod Inc Makrolidi
WO2011018510A1 (en) * 2009-08-13 2011-02-17 Basilea Pharmaceutica Ag New macrolides and their use

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
EP0559896B1 (de) * 1990-11-28 1997-08-27 Taisho Pharmaceutical Co. Ltd 6-0-methylerythromycin a-derivat
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PL327146A1 (en) * 1995-12-14 1998-11-23 Merck & Co Inc Antagonists of the gonadotrophin liberating hormone
ES2252784T3 (es) * 1996-05-07 2006-05-16 Abbott Laboratories Compuestos a base de eritromicina 6-0 sustituida y tecnica de produccion.

Also Published As

Publication number Publication date
WO1999050275A2 (en) 1999-10-07
CA2325521A1 (en) 1999-10-07
BR9909080A (pt) 2000-12-12
TR200002767T2 (tr) 2001-05-21
JP2002509937A (ja) 2002-04-02
AU3067499A (en) 1999-10-18
BG104844A (en) 2001-07-31
NO20004860D0 (no) 2000-09-27
PL348242A1 (en) 2002-05-20
PT1066304E (pt) 2005-06-30
CN1307584A (zh) 2001-08-08
EP1066304A1 (de) 2001-01-10
IL138219A0 (en) 2001-10-31
NO20004860L (no) 2000-11-24
KR20010034694A (ko) 2001-04-25
HUP0102011A3 (en) 2003-07-28
ES2238828T3 (es) 2005-09-01
DE69923835D1 (de) 2005-03-31
SK13972000A3 (sk) 2001-07-10
WO1999050275A3 (en) 2001-02-22
EP1066304B1 (de) 2005-02-23
US5955440A (en) 1999-09-21
HUP0102011A2 (hu) 2001-11-28
DE69923835T2 (de) 2006-04-06
HK1036284A1 (en) 2001-12-28

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