DK1054672T3 - Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater - Google Patents

Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater

Info

Publication number
DK1054672T3
DK1054672T3 DK99903752T DK99903752T DK1054672T3 DK 1054672 T3 DK1054672 T3 DK 1054672T3 DK 99903752 T DK99903752 T DK 99903752T DK 99903752 T DK99903752 T DK 99903752T DK 1054672 T3 DK1054672 T3 DK 1054672T3
Authority
DK
Denmark
Prior art keywords
preparation
pharmaceutical compositions
morphine sulfate
sulfate microgranules
microgranules
Prior art date
Application number
DK99903752T
Other languages
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Application granted granted Critical
Publication of DK1054672T3 publication Critical patent/DK1054672T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK99903752T 1998-02-16 1999-02-15 Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater DK1054672T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9801816A FR2774910B1 (fr) 1998-02-16 1998-02-16 Microgranules de sulfate de morphine, procede de fabrication et preparations pharmaceutiques
PCT/FR1999/000326 WO1999040918A1 (fr) 1998-02-16 1999-02-15 Microgranules de sulfate de morphine, procede de fabrication et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
DK1054672T3 true DK1054672T3 (da) 2007-04-10

Family

ID=9522990

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99903752T DK1054672T3 (da) 1998-02-16 1999-02-15 Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater

Country Status (15)

Country Link
US (2) US6482437B2 (da)
EP (1) EP1054672B1 (da)
JP (1) JP4447166B2 (da)
CN (1) CN1135981C (da)
AU (1) AU2429899A (da)
BR (1) BR9907908A (da)
CA (1) CA2320878C (da)
CY (1) CY1107559T1 (da)
DE (1) DE69934781T2 (da)
DK (1) DK1054672T3 (da)
ES (1) ES2277427T3 (da)
FR (1) FR2774910B1 (da)
NZ (1) NZ506307A (da)
PT (1) PT1054672E (da)
WO (1) WO1999040918A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
WO2004084868A1 (en) 2003-03-26 2004-10-07 Egalet A/S Morphine controlled release system
KR101148734B1 (ko) * 2003-10-10 2012-07-05 에띠빠흠 징코 빌로바 추출물을 포함하는 서방형 미세과립 및 이것을 제조하는 방법
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
US8821928B2 (en) 2007-06-04 2014-09-02 Egalet Ltd. Controlled release pharmaceutical compositions for prolonged effect
AU2008296971B2 (en) * 2007-09-03 2014-10-02 Nanoshift, Llc Particulate compositions for delivery of poorly soluble drugs
CA2751667C (en) 2009-02-06 2016-12-13 Egalet Ltd. Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
AU2013285988A1 (en) 2012-07-06 2015-02-12 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
US9683448B2 (en) 2013-03-18 2017-06-20 Honeywell International Inc. Low conductivity thermal barrier coating
US11479846B2 (en) 2014-01-07 2022-10-25 Honeywell International Inc. Thermal barrier coatings for turbine engine components

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4135514A (en) * 1974-12-23 1979-01-23 Alza Corporation Osmotic releasing system for administering ophthalmic drug to eye of animal
US4309996A (en) * 1980-04-28 1982-01-12 Alza Corporation System with microporous releasing diffusor
US4673405A (en) * 1983-03-04 1987-06-16 Alza Corporation Osmotic system with instant drug availability
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
DE3708856A1 (de) 1987-03-18 1988-09-29 Kajetan Leitner Mit zaehnen versehene einpressmutter
US5202128A (en) * 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
US5582838A (en) * 1994-12-22 1996-12-10 Merck & Co., Inc. Controlled release drug suspension delivery device
US6066339A (en) * 1997-10-17 2000-05-23 Elan Corporation, Plc Oral morphine multiparticulate formulation

Also Published As

Publication number Publication date
CA2320878A1 (fr) 1999-08-19
DE69934781T2 (de) 2007-10-11
US20020028246A1 (en) 2002-03-07
CA2320878C (fr) 2009-04-21
WO1999040918A1 (fr) 1999-08-19
PT1054672E (pt) 2007-04-30
HK1036402A1 (en) 2002-01-04
JP4447166B2 (ja) 2010-04-07
US6482437B2 (en) 2002-11-19
CN1291097A (zh) 2001-04-11
FR2774910A1 (fr) 1999-08-20
BR9907908A (pt) 2002-04-30
CN1135981C (zh) 2004-01-28
DE69934781D1 (de) 2007-02-22
US20030129244A1 (en) 2003-07-10
EP1054672B1 (fr) 2007-01-10
CY1107559T1 (el) 2013-03-13
FR2774910B1 (fr) 2001-09-07
ES2277427T3 (es) 2007-07-01
JP2002502877A (ja) 2002-01-29
EP1054672A1 (fr) 2000-11-29
AU2429899A (en) 1999-08-30
NZ506307A (en) 2003-11-28

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