EE200100196A - a-tsüklodekstriinil põhinevad farmatseutilised kompositsioonid LH-RH analoogide peroraalseks manustamiseks - Google Patents

a-tsüklodekstriinil põhinevad farmatseutilised kompositsioonid LH-RH analoogide peroraalseks manustamiseks

Info

Publication number: EE200100196A
Authority: EE; Estonia
Prior art keywords: analogs; pharmaceutical compositions; oral administration; based pharmaceutical; cyclodextrin based
Prior art date: 1998-09-30

Application number

EEP200100196A

Other languages

English (en)

Inventor

Delansorne R�mi

Bonnet Paule

Paris Jacques

Original Assignee

Laboratoire Theramex

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-30

Filing date

1999-09-23

Publication date

2002-06-17

1999-09-23 Application filed by Laboratoire Theramex filed Critical Laboratoire Theramex

2002-06-17 Publication of EE200100196A publication Critical patent/EE200100196A/et

2007-08-15 Publication of EE04872B1 publication Critical patent/EE04872B1/et

Links

229920001450 Alpha-Cyclodextrin Polymers 0.000 title 1
HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 title 1
229940043377 alpha-cyclodextrin Drugs 0.000 title 1
XLXSAKCOAKORKW-AQJXLSMYSA-N gonadorelin Chemical class C([C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)NCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 XLXSAKCOAKORKW-AQJXLSMYSA-N 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Endocrinology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Inorganic Chemistry (AREA)
Zoology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

EEP200100196A 1998-09-30 1999-09-23 a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks EE04872B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98402403A EP0998940A1 (en)	1998-09-30	1998-09-30	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues
PCT/EP1999/007389 WO2000018423A1 (en)	1998-09-30	1999-09-23	Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of lh-rh analogues

Publications (2)

Publication Number	Publication Date
EE200100196A true EE200100196A (et)	2002-06-17
EE04872B1 EE04872B1 (et)	2007-08-15

Family

ID=8235503

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200100196A EE04872B1 (et)	1998-09-30	1999-09-23	a-tsklodekstriini v?i selle derivaadi kasutamineLH-RH peptiidanaloogi sisaldavate farmatseutiliste kompositsioonide valmistamiseks ja a-tsklodekstriinil p?hinev farmatseutiline kompositsioon LH-RHpeptiidanaloogide peroraalseks manustamiseks

Country Status (28)

Country	Link
EP (2)	EP0998940A1 (et)
JP (1)	JP4485060B2 (et)
KR (1)	KR100652457B1 (et)
CN (1)	CN1200727C (et)
AR (1)	AR023056A1 (et)
AT (1)	ATE218358T1 (et)
AU (1)	AU756233B2 (et)
BR (1)	BR9914125A (et)
CA (1)	CA2344470C (et)
CZ (1)	CZ302343B6 (et)
DE (1)	DE69901721T2 (et)
DK (1)	DK1117420T3 (et)
EE (1)	EE04872B1 (et)
ES (1)	ES2178478T3 (et)
HK (1)	HK1042047B (et)
HU (1)	HUP0103649A3 (et)
ID (1)	ID28650A (et)
IL (2)	IL142112A0 (et)
MX (1)	MXPA01003340A (et)
NO (1)	NO330234B1 (et)
NZ (1)	NZ510446A (et)
PL (1)	PL200693B1 (et)
PT (1)	PT1117420E (et)
RU (1)	RU2214270C2 (et)
SI (1)	SI1117420T1 (et)
TR (1)	TR200100887T2 (et)
WO (1)	WO2000018423A1 (et)
ZA (1)	ZA200102452B (et)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10024451A1 (de) *	2000-05-18	2001-11-29	Asta Medica Ag	Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
SE0104462D0 (sv) *	2001-12-29	2001-12-29	Carlbiotech Ltd As	Peptide purifcation (Peptidrening)
CN100486641C (zh) *	2006-08-11	2009-05-13	南京师范大学	口服复方骨肽药物组合物及其制备方法
WO2024210903A1 (en) *	2023-04-07	2024-10-10	Najib Lamharzi	Modified peptide ligands for stable delivery of highly potent payloads to tumors: method of making and using same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4659696A (en) *	1982-04-30	1987-04-21	Takeda Chemical Industries, Ltd.	Pharmaceutical composition and its nasal or vaginal use
US4659969A (en) *	1984-08-09	1987-04-21	Synektron Corporation	Variable reluctance actuator having position sensing and control
PT88490B (pt) *	1987-09-14	1992-11-30	Novo Nordisk As	Processo para a preparacao de composicoes farmaceuticas para libertacao nao-enterica trans-mucosa contendo monossacaridos ou oligossacaridos
SI9300470A (en) *	1993-09-10	1995-04-30	Lek Tovarna Farmacevtskih	Inclusion complexes of optically active and racemic ibuproxan with cyclodextrin derivates,process for their preparation,pharmaceutical preparations comprising the same and their use
JPH11292787A (ja) *	1995-08-15	1999-10-26	Asahi Chem Ind Co Ltd	生理活性ペプチドを含有する経粘膜投与製剤
AU1808897A (en) *	1995-12-13	1997-07-03	Dullatur Limited	A calcitonin preparation
ES2221019T3 (es) *	1996-10-31	2004-12-16	Takeda Chemical Industries, Ltd.	Preparacion de liberacion mantenida.
EP0842946A1 (en) *	1996-11-14	1998-05-20	Laboratoire Theramex S.A.	Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them

1998
- 1998-09-30 EP EP98402403A patent/EP0998940A1/en not_active Withdrawn
1999
- 1999-09-23 HK HK02103697.8A patent/HK1042047B/zh not_active IP Right Cessation
- 1999-09-23 AT AT99948935T patent/ATE218358T1/de active
- 1999-09-23 MX MXPA01003340A patent/MXPA01003340A/es not_active IP Right Cessation
- 1999-09-23 TR TR2001/00887T patent/TR200100887T2/xx unknown
- 1999-09-23 ES ES99948935T patent/ES2178478T3/es not_active Expired - Lifetime
- 1999-09-23 AU AU61999/99A patent/AU756233B2/en not_active Ceased
- 1999-09-23 PT PT99948935T patent/PT1117420E/pt unknown
- 1999-09-23 IL IL14211299A patent/IL142112A0/xx active IP Right Grant
- 1999-09-23 HU HU0103649A patent/HUP0103649A3/hu unknown
- 1999-09-23 CN CNB99812589XA patent/CN1200727C/zh not_active Expired - Fee Related
- 1999-09-23 SI SI9930098T patent/SI1117420T1/xx unknown
- 1999-09-23 EP EP99948935A patent/EP1117420B1/en not_active Expired - Lifetime
- 1999-09-23 CZ CZ20011173A patent/CZ302343B6/cs not_active IP Right Cessation
- 1999-09-23 EE EEP200100196A patent/EE04872B1/et not_active IP Right Cessation
- 1999-09-23 CA CA002344470A patent/CA2344470C/en not_active Expired - Fee Related
- 1999-09-23 DE DE69901721T patent/DE69901721T2/de not_active Expired - Lifetime
- 1999-09-23 RU RU2001111842/14A patent/RU2214270C2/ru not_active IP Right Cessation
- 1999-09-23 DK DK99948935T patent/DK1117420T3/da active
- 1999-09-23 BR BR9914125-6A patent/BR9914125A/pt not_active IP Right Cessation
- 1999-09-23 NZ NZ510446A patent/NZ510446A/xx not_active IP Right Cessation
- 1999-09-23 PL PL346939A patent/PL200693B1/pl not_active IP Right Cessation
- 1999-09-23 JP JP2000571940A patent/JP4485060B2/ja not_active Expired - Fee Related
- 1999-09-23 WO PCT/EP1999/007389 patent/WO2000018423A1/en not_active Ceased
- 1999-09-23 ZA ZA200102452A patent/ZA200102452B/en unknown
- 1999-09-23 KR KR1020017003614A patent/KR100652457B1/ko not_active Expired - Fee Related
- 1999-09-23 ID IDW20010683A patent/ID28650A/id unknown
- 1999-09-30 AR ARP990104932A patent/AR023056A1/es not_active Application Discontinuation
2001
- 2001-03-19 IL IL142112A patent/IL142112A/en not_active IP Right Cessation
- 2001-03-28 NO NO20011576A patent/NO330234B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK1117420T3 (da)	2002-09-16
NO20011576D0 (no)	2001-03-28
AU6199999A (en)	2000-04-17
CN1324241A (zh)	2001-11-28
ZA200102452B (en)	2002-03-26
KR20010075255A (ko)	2001-08-09
ID28650A (id)	2001-06-21
CZ302343B6 (cs)	2011-03-23
DE69901721D1 (de)	2002-07-11
HK1042047B (zh)	2005-12-16
PL200693B1 (pl)	2009-01-30
CA2344470A1 (en)	2000-04-06
CN1200727C (zh)	2005-05-11
SI1117420T1 (en)	2002-12-31
NO20011576L (no)	2001-03-28
AR023056A1 (es)	2002-09-04
CA2344470C (en)	2009-01-06
JP4485060B2 (ja)	2010-06-16
HUP0103649A3 (en)	2002-05-28
EP0998940A1 (en)	2000-05-10
JP2002525336A (ja)	2002-08-13
IL142112A (en)	2006-10-31
CZ20011173A3 (cs)	2001-09-12
NO330234B1 (no)	2011-03-07
RU2214270C2 (ru)	2003-10-20
DE69901721T2 (de)	2003-01-09
AU756233B2 (en)	2003-01-09
EE04872B1 (et)	2007-08-15
TR200100887T2 (tr)	2001-10-22
NZ510446A (en)	2003-01-31
MXPA01003340A (es)	2004-04-21
IL142112A0 (en)	2002-03-10
BR9914125A (pt)	2001-06-19
PL346939A1 (en)	2002-03-11
HUP0103649A2 (hu)	2002-02-28
EP1117420A1 (en)	2001-07-25
ES2178478T3 (es)	2002-12-16
EP1117420B1 (en)	2002-06-05
WO2000018423A1 (en)	2000-04-06
KR100652457B1 (ko)	2006-11-30
ATE218358T1 (de)	2002-06-15
PT1117420E (pt)	2002-10-31

Legal Events

Date	Code	Title	Description
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231
2012-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20110923

Publication	Publication Date	Title
PL342988A1 (en)	2001-07-16	Novel galenic formulations of meloxicam for oral administration
NO20002851D0 (no)	2000-06-02	Blandinger for nasal administrasjon av medikamenter
NO20020208L (no)	2002-03-18	Flytende sammensetninger for oral administrasjon
EE04578B1 (et)	2006-02-15	Farmatseutiline kompositsioon N-piperidino-3-pürasoolkarboksamiidi derivaadi, tema soolade ja nendesolvaatide suu kaudu manustamiseks
DK0876131T3 (da)	2014-11-24	Sammensætninger til lægemiddelindgivelse til forbedret stabilitet af androgener
HUP0302319A3 (en)	2013-04-29	Pharmaceutical composition for oral administration of active ingredient
FI955310L (fi)	1996-05-09	Farmaseuttinen koostumus flavonoidien antamiseksi oraalisesti
FI951357L (fi)	1995-09-25	Farmaseuttiset koostumukset, jotka mahdollistavat trimetatsidiinin hidastetun vapautumisen oraalisen annostuksen jälkeen
ITMI982222A0 (it)	1998-10-16	Composizioni farmaceutiche orali contenenti buprenorfina
EE200200075A (et)	2003-04-15	Peroraalselt ja paikselt manustatavad farmatseutilised kompositsioonid
NO991613L (no)	1999-04-06	Farmas°ytiske mikrosfµrer av valpronsyre for oral administrering
NO993927D0 (no)	1999-08-16	Farmasöytiske blandinger i törr form for oral administrasjon av en syklisk kvaternær ammoniumforbindelse
NO996044L (no)	1999-12-08	Rapamycinformuleringer for oral administrasjon
NO20011576D0 (no)	2001-03-28	Farmasöytiske blandinger basert på <alfa>-cyklodekstrin for oral administrasjon av LH-RH analoger
IT9021021A0 (it)	1990-07-23	Composizioni farmaceutiche per la somministrazione orale di irudina
ES2170168T3 (es)	2002-08-01	Composiciones recubiertas entericamente de derivados de 1,5-benzodiacepina con actividad antagonista o agonista de cck.
NO20032581D0 (no)	2003-06-06	Farmasöytisk formulering av gepiron for oral administrering
ITMI992736A0 (it)	1999-12-29	Composizioni farmaceutiche per la somministrazione localizzata nel cav o orale di farmaci antiinfiammatori non stereoidei utili per la terapi
ITMI20010009A0 (it)	2001-01-03	Composizioni farmaceutica contenente brivudina per la singola somministrazione giornaliera
DK1165081T3 (da)	2005-06-20	Fremgangsmåde til fremstilling af tolperisonholdige farmaceutiske præparater til oral indgivelse
NO20003284L (no)	2000-08-24	Farmasøytisk preparat for oral administrering
KR970701559A (ko)	1997-04-12	펩타이드의 경구 투여를 위한 안정화된 조성물(stabilized composition for oral administration of peptides)
AU6349599A (en)	2000-05-22	Use of xanthan gums for preparing pharmaceutical compositions
ITMI920214A0 (it)	1992-02-05	Composizioni farmaceutiche stabili per la somministrazione orale di calcitonina
ITPD920141A0 (it)	1992-07-30	Formulazione farmaceutiche per la somministraziane orale di calcitoni-na