ATE290077T1 - Regulierte gene und ihre verwendungen - Google Patents

Regulierte gene und ihre verwendungen

Info

Publication number
ATE290077T1
ATE290077T1 AT96932771T AT96932771T ATE290077T1 AT E290077 T1 ATE290077 T1 AT E290077T1 AT 96932771 T AT96932771 T AT 96932771T AT 96932771 T AT96932771 T AT 96932771T AT E290077 T1 ATE290077 T1 AT E290077T1
Authority
AT
Austria
Prior art keywords
regulated genes
protein
therapy
mitogenic activity
purposes
Prior art date
Application number
AT96932771T
Other languages
English (en)
Inventor
Salvatore Oliviero
Original Assignee
Univ Siena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26307843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290077(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9519928.7A external-priority patent/GB9519928D0/en
Priority claimed from GBGB9612368.2A external-priority patent/GB9612368D0/en
Application filed by Univ Siena filed Critical Univ Siena
Application granted granted Critical
Publication of ATE290077T1 publication Critical patent/ATE290077T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
AT96932771T 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen ATE290077T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9519928.7A GB9519928D0 (en) 1995-09-29 1995-09-29 Regulated genes and uses thereof
GBGB9612368.2A GB9612368D0 (en) 1996-06-13 1996-06-13 Regulated genes and uses thereof
PCT/IB1996/001113 WO1997012972A2 (en) 1995-09-29 1996-09-30 Regulated genes and uses thereof

Publications (1)

Publication Number Publication Date
ATE290077T1 true ATE290077T1 (de) 2005-03-15

Family

ID=26307843

Family Applications (2)

Application Number Title Priority Date Filing Date
AT05001932T ATE459715T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen
AT96932771T ATE290077T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT05001932T ATE459715T1 (de) 1995-09-29 1996-09-30 Regulierte gene und ihre verwendungen

Country Status (11)

Country Link
US (1) US8383788B2 (de)
EP (2) EP1553182B1 (de)
JP (1) JP4086315B2 (de)
AT (2) ATE459715T1 (de)
AU (1) AU7142996A (de)
CA (1) CA2230957A1 (de)
DE (2) DE69638142D1 (de)
ES (2) ES2341864T3 (de)
IL (1) IL123649A0 (de)
NO (1) NO981353D0 (de)
WO (1) WO1997012972A2 (de)

Families Citing this family (34)

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US6824777B1 (en) 1992-10-09 2004-11-30 Licentia Ltd. Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
US7423125B2 (en) 1995-08-01 2008-09-09 Vegenics Limited Antibodies to VEGF-C
ES2202469T5 (es) 1995-09-08 2011-06-06 Genentech, Inc. Proteína relacionada con el vegf.
DE69638142D1 (de) 1995-09-29 2010-04-15 Univ Siena Regulierte Gene und ihre Verwendungen
WO1998002543A1 (fr) * 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
EP1283268A3 (de) * 1996-08-23 2004-01-02 Ludwig Institute For Cancer Research Rekombinantes Vasculäres Endothelzellen Wachstumsfaktor D (VEGF-D)
AU5439998A (en) * 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
US7125714B2 (en) 1997-02-05 2006-10-24 Licentia Ltd. Progenitor cell materials and methods
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
CA2315977A1 (en) * 1997-12-24 1999-07-08 Ludwig Institute For Cancer Research Expression vectors and cell lines expressing vascular endothelial growth factor d, and method of treating melanomas
DE19847422C1 (de) * 1998-10-14 2000-01-13 Forschungszentrum Juelich Gmbh Chinese-Hamster-Ovary-Zellen zur Produktion von Proteinen
DK1137773T3 (da) 1998-12-07 2008-12-08 Zymogenetics Inc Væsktfaktorhomolog ZVEGF3
WO2001012669A1 (en) * 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
AU2001239884B2 (en) 2000-02-25 2006-08-10 Vegenics Limited Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators
US7611711B2 (en) 2001-01-17 2009-11-03 Vegenics Limited VEGFR-3 inhibitor materials and methods
CA2435503C (en) 2001-01-19 2011-02-22 Ludwig Institute For Cancer Research Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
CN1555488A (zh) * 2001-07-12 2004-12-15 路德维格癌症研究院 淋巴管内皮细胞物质及方法
US20030113324A1 (en) * 2001-10-01 2003-06-19 Kari Alitalo Neuropilin/VEGF-C/VEGFR-3 materials and methods
US20040214766A1 (en) * 2001-10-01 2004-10-28 Kari Alitalo VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
EP1635860A2 (de) * 2003-06-12 2006-03-22 Ludwig Institute For Cancer Research Verwendung von vegf-c oder vegf-d in der wiederherstellende chirurgie
WO2005016963A2 (en) * 2003-06-12 2005-02-24 Ludwig Institute For Cancer Research Heparin binding veger-3 ligands
WO2005087177A2 (en) 2004-03-05 2005-09-22 Ludwig Institute For Cancer Research Chimeric anti-vegf-d antibodies and humanized anti-vegf-d antibodies and methods of using same
ITRM20050367A1 (it) * 2005-07-08 2007-01-09 Univ Siena Uso del vegf-d o di suoi frammenti funzionalmente attivi per la ricostruzione o per la riparazione ossea.
EP1919944B1 (de) 2005-08-15 2011-03-23 Vegenics Pty Ltd Modifizierte vegf und pdgf mit verbesserten angiogenen eigenschaften
WO2008093246A2 (en) 2007-02-02 2008-08-07 Vegenics Limited Vegf receptor antagonist for treating organ transplant alloimmunity and arteriosclerosis
US8571840B2 (en) * 2007-03-28 2013-10-29 Autodesk, Inc. Constraint reduction for dynamic simulation
WO2011154308A1 (en) 2010-06-08 2011-12-15 Proyecto De Biomedicina Cima, S.L. New compositions and cell therapy methods for the treatment of cirrhosis
JP6272781B2 (ja) 2012-01-06 2018-01-31 エンボライン， インコーポレイテッド 統合された塞栓保護デバイス
RS60026B1 (sr) 2013-02-18 2020-04-30 Vegenics Pty Ltd Molekuli koji vezuju ligande i njihove upotrebe
US11578110B2 (en) 2015-08-25 2023-02-14 Histide Ag Compounds for inducing tissue formation and uses thereof
EP4541810A3 (de) * 2015-08-25 2026-03-18 Histide AG Verbindungen zur induktion von geweberegeneration und verwendungen davon
US10617509B2 (en) 2015-12-29 2020-04-14 Emboline, Inc. Multi-access intraprocedural embolic protection device
JP7557475B2 (ja) 2019-02-13 2024-09-27 エンボライン， インコーポレイテッド 統合された塞栓保護デバイスを伴うカテーテル

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135983D0 (da) 1983-03-25 1983-03-25 Novo Industri As Maltogen amylaseenzymprodukt og fremgangsmade til dets fremstilling og anvendelse
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5968778A (en) * 1989-01-12 1999-10-19 Jurgen Hoppe PDGF-AB, preparation process and pharmaceuticals containing them
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
JP3024311B2 (ja) 1991-10-03 2000-03-21 味の素株式会社 Ｉｌ−２受容体重鎖に結合するポリペプチド
JPH05271294A (ja) 1992-01-24 1993-10-19 Japan Found Cancer Res ヒトプロヒビチンおよびそれをコードするｄｎａ
US5599559A (en) 1992-07-27 1997-02-04 Pfizer Inc. Calcium channel blocking polypeptide from agelenopsis aperta and therapeutic methods employing it
EP0751992B1 (de) * 1994-03-08 2005-11-09 Human Genome Sciences, Inc. Vaskularer endothelialer wachstumsfaktor 2
US5814464A (en) 1994-10-07 1998-09-29 Regeneron Pharma Nucleic acids encoding TIE-2 ligand-2
US6221839B1 (en) * 1994-11-14 2001-04-24 Helsinki University Licensing Ltd. Oy FIt4 ligand and methods of use
US6645933B1 (en) 1995-08-01 2003-11-11 Helsinki University Licensing Ltd. Oy Receptor ligand VEGF-C
JPH08185216A (ja) 1994-12-28 1996-07-16 Meidensha Corp 工具姿勢パラメータ設定方法及びロボット制御装置
US5928939A (en) 1995-03-01 1999-07-27 Ludwig Institute For Cancer Research Vascular endothelial growth factor-b and dna coding therefor
EP0815221B1 (de) 1995-03-02 2003-10-22 AMRAD Operations Pty.,Ltd. Ein neuartiger wachstumfaktor und eine genetische sequenz die für diesen kodiert
WO1996039421A1 (en) 1995-06-06 1996-12-12 Human Genome Sciences, Inc. Human vascular endothelial growth factor 3
DE69638142D1 (de) 1995-09-29 2010-04-15 Univ Siena Regulierte Gene und ihre Verwendungen
WO1998002543A1 (fr) 1996-07-15 1998-01-22 Chugai Research Institute For Molecular Medicine, Inc. Nouveaux facteurs analogues au vegf
EP1283268A3 (de) * 1996-08-23 2004-01-02 Ludwig Institute For Cancer Research Rekombinantes Vasculäres Endothelzellen Wachstumsfaktor D (VEGF-D)
AU5439998A (en) 1996-12-06 1998-06-29 Zymogenetics Inc. Vascular endothelial growth factor
CN1248286A (zh) 1997-02-18 2000-03-22 路德维格癌症研究所 含有重组血管内皮生长因子b(vegf－b)dna的转基因动物及其用途
WO2000037025A2 (en) * 1998-12-21 2000-06-29 Ludwig Institute For Cancer Research Antibodies to truncated vegf-d and uses thereof
WO2001012669A1 (en) 1999-08-16 2001-02-22 Universita' Degli Studi Di Siena Vegf-d and angiogenic use thereof
NZ587143A (en) 2008-02-12 2011-07-29 Dow Agrosciences Llc Pesticidal compositions

Also Published As

Publication number Publication date
JP4086315B2 (ja) 2008-05-14
CA2230957A1 (en) 1997-04-10
ES2341864T3 (es) 2010-06-29
WO1997012972A2 (en) 1997-04-10
EP0853668B2 (de) 2013-03-06
EP0853668B1 (de) 2005-03-02
WO1997012972A3 (en) 1997-06-12
ES2239338T5 (es) 2013-05-31
NO981353L (no) 1998-03-25
ES2239338T3 (es) 2005-09-16
EP1553182A3 (de) 2008-03-05
US20020123481A1 (en) 2002-09-05
DE69634412T2 (de) 2005-12-15
JP2001501442A (ja) 2001-02-06
NO981353D0 (no) 1998-03-25
DE69638142D1 (de) 2010-04-15
IL123649A0 (en) 1998-10-30
EP0853668A2 (de) 1998-07-22
EP1553182B1 (de) 2010-03-03
DE69634412D1 (de) 2005-04-07
EP1553182A2 (de) 2005-07-13
DE69634412T3 (de) 2013-07-04
US8383788B2 (en) 2013-02-26
ATE459715T1 (de) 2010-03-15
AU7142996A (en) 1997-04-28

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Legal Events

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