DK0751992T3 - Karendotelvækstfaktor 2 - Google Patents
Karendotelvækstfaktor 2Info
- Publication number
- DK0751992T3 DK0751992T3 DK94923874T DK94923874T DK0751992T3 DK 0751992 T3 DK0751992 T3 DK 0751992T3 DK 94923874 T DK94923874 T DK 94923874T DK 94923874 T DK94923874 T DK 94923874T DK 0751992 T3 DK0751992 T3 DK 0751992T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptide
- vegf2
- karendothelial
- growth factor
- antibodies
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 239000005557 antagonist Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000001225 therapeutic effect Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20755094A | 1994-03-08 | 1994-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0751992T3 true DK0751992T3 (da) | 2006-03-06 |
Family
ID=22771051
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94923874T DK0751992T3 (da) | 1994-03-08 | 1994-05-12 | Karendotelvækstfaktor 2 |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US5935820A (da) |
| EP (1) | EP0751992B1 (da) |
| JP (4) | JPH09510093A (da) |
| CN (1) | CN1267550C (da) |
| AT (1) | ATE309360T1 (da) |
| AU (1) | AU696764B2 (da) |
| CA (2) | CA2184584C (da) |
| DE (1) | DE69434538T2 (da) |
| DK (1) | DK0751992T3 (da) |
| ES (1) | ES2249762T3 (da) |
| WO (1) | WO1995024473A1 (da) |
| ZA (1) | ZA943464B (da) |
Families Citing this family (93)
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| US6824777B1 (en) | 1992-10-09 | 2004-11-30 | Licentia Ltd. | Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
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| US7109308B1 (en) | 1994-03-08 | 2006-09-19 | Human Genome Sciences, Inc. | Antibodies to human vascular endothelial growth factor 2 |
| US6608182B1 (en) | 1994-03-08 | 2003-08-19 | Human Genome Sciences, Inc. | Human vascular endothelial growth factor 2 |
| US6734285B2 (en) | 1994-03-08 | 2004-05-11 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 proteins and compositions |
| US6040157A (en) | 1994-03-08 | 2000-03-21 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| ES2249762T3 (es) | 1994-03-08 | 2006-04-01 | Human Genome Sciences, Inc. | Factor de crecimiento del endotelio vascular 2. |
| US5932540A (en) | 1994-03-08 | 1999-08-03 | Human Genome Sciences, Inc. | Vascular endothelial growth factor 2 |
| US6645933B1 (en) | 1995-08-01 | 2003-11-11 | Helsinki University Licensing Ltd. Oy | Receptor ligand VEGF-C |
| US6403088B1 (en) | 1995-08-01 | 2002-06-11 | Helsinki University Licensing, Ltd. | Antibodies reactive with VEGF-C, a ligand for the Flt4 receptor tyrosine kinase (VEGFR-3) |
| US6221839B1 (en) * | 1994-11-14 | 2001-04-24 | Helsinki University Licensing Ltd. Oy | FIt4 ligand and methods of use |
| EP1353952B1 (en) | 1994-11-14 | 2007-04-11 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
| US6818220B1 (en) | 1994-11-14 | 2004-11-16 | Licentia Ltd. | Vascular endothelial growth factor C (VEGF-C) protein and gene mutants thereof, and uses thereof |
| US6130071A (en) * | 1997-02-05 | 2000-10-10 | Helsinki University Licensing, Ltd. | Vascular endothelial growth factor C (VEGF-C) ΔCys156 protein and gene, and uses thereof |
| US6245530B1 (en) | 1995-08-01 | 2001-06-12 | Ludwig Institute For Cancer Research | Receptor ligand |
| US5607918A (en) * | 1995-03-01 | 1997-03-04 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-B and DNA coding therefor |
| US5928939A (en) | 1995-03-01 | 1999-07-27 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor-b and dna coding therefor |
| US7160991B1 (en) | 1995-03-02 | 2007-01-09 | Ludwig Institute For Cancer Research | Vascular endothelial growth factor polypeptides |
| NZ301611A (en) * | 1995-03-02 | 2000-02-28 | Amrad Operations Pty Ltd | a peptide having vascular endothelial growth factor like properties, nucleic acid molecule encoding it and its use |
| AU2005244575B2 (en) * | 1995-06-06 | 2008-06-05 | Human Genome Sciences, Inc. | Human Vascular Endothelial Growth Factor 2 |
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| US7423125B2 (en) | 1995-08-01 | 2008-09-09 | Vegenics Limited | Antibodies to VEGF-C |
| AU2003201371B2 (en) * | 1995-08-01 | 2007-03-01 | Helsinki University Licensing Ltd. Oy | Receptor Ligand VEGF-C |
| DE69628652T3 (de) | 1995-09-08 | 2012-05-03 | Genentech, Inc. | Vegf-verwandtes protein |
| DE69634412T3 (de) | 1995-09-29 | 2013-07-04 | Vegenics Pty Ltd | Regulierte gene und ihre verwendungen |
| US6994989B1 (en) | 1995-11-08 | 2006-02-07 | Immunex Corp. | FLK-1 binding proteins |
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-
1994
- 1994-05-12 ES ES94923874T patent/ES2249762T3/es not_active Expired - Lifetime
- 1994-05-12 AU AU73941/94A patent/AU696764B2/en not_active Ceased
- 1994-05-12 WO PCT/US1994/005291 patent/WO1995024473A1/en not_active Ceased
- 1994-05-12 CN CNB941950530A patent/CN1267550C/zh not_active Expired - Fee Related
- 1994-05-12 JP JP7523422A patent/JPH09510093A/ja not_active Withdrawn
- 1994-05-12 AT AT94923874T patent/ATE309360T1/de not_active IP Right Cessation
- 1994-05-12 EP EP94923874A patent/EP0751992B1/en not_active Revoked
- 1994-05-12 DK DK94923874T patent/DK0751992T3/da active
- 1994-05-12 DE DE69434538T patent/DE69434538T2/de not_active Revoked
- 1994-05-12 CA CA002184584A patent/CA2184584C/en not_active Expired - Fee Related
- 1994-05-12 CA CA002414016A patent/CA2414016A1/en not_active Abandoned
- 1994-05-19 ZA ZA943464A patent/ZA943464B/xx unknown
-
1997
- 1997-03-27 US US08/824,996 patent/US5935820A/en not_active Expired - Fee Related
-
2002
- 2002-02-01 US US10/060,523 patent/US20020182683A1/en not_active Abandoned
-
2003
- 2003-08-11 JP JP2003291861A patent/JP2004000267A/ja not_active Withdrawn
-
2004
- 2004-05-26 US US10/853,232 patent/US7498417B2/en not_active Expired - Fee Related
-
2006
- 2006-03-17 JP JP2006075735A patent/JP2006333865A/ja not_active Withdrawn
- 2006-05-15 JP JP2006135885A patent/JP4439490B2/ja not_active Expired - Fee Related
-
2009
- 2009-03-02 US US12/396,033 patent/US20090192088A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN1267550C (zh) | 2006-08-02 |
| CA2184584C (en) | 2003-04-08 |
| DE69434538D1 (de) | 2005-12-15 |
| US20090192088A1 (en) | 2009-07-30 |
| EP0751992A1 (en) | 1997-01-08 |
| ZA943464B (en) | 1995-11-20 |
| JP2006333865A (ja) | 2006-12-14 |
| WO1995024473A1 (en) | 1995-09-14 |
| JP2004000267A (ja) | 2004-01-08 |
| CN1145636A (zh) | 1997-03-19 |
| CA2414016A1 (en) | 1995-09-14 |
| JPH09510093A (ja) | 1997-10-14 |
| AU696764C (en) | 1995-09-25 |
| ATE309360T1 (de) | 2005-11-15 |
| US20020182683A1 (en) | 2002-12-05 |
| EP0751992A4 (en) | 1997-12-17 |
| US7498417B2 (en) | 2009-03-03 |
| US20040214286A1 (en) | 2004-10-28 |
| US5935820A (en) | 1999-08-10 |
| JP2006238893A (ja) | 2006-09-14 |
| AU696764B2 (en) | 1998-09-17 |
| CA2184584A1 (en) | 1995-09-14 |
| AU7394194A (en) | 1995-09-25 |
| DE69434538T2 (de) | 2006-08-10 |
| JP4439490B2 (ja) | 2010-03-24 |
| ES2249762T3 (es) | 2006-04-01 |
| EP0751992B1 (en) | 2005-11-09 |
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