ATE290405T1 - Verfahren zur herstellung von diagnostica - Google Patents
Verfahren zur herstellung von diagnosticaInfo
- Publication number
- ATE290405T1 ATE290405T1 AT99203198T AT99203198T ATE290405T1 AT E290405 T1 ATE290405 T1 AT E290405T1 AT 99203198 T AT99203198 T AT 99203198T AT 99203198 T AT99203198 T AT 99203198T AT E290405 T1 ATE290405 T1 AT E290405T1
- Authority
- AT
- Austria
- Prior art keywords
- microcapsules
- wall
- forming material
- diagnostica
- producing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasonic imaging preparations
- A61K49/222—Echographic preparations; Ultrasonic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/225—Microparticles, microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
- B01J13/043—Drying and spraying
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
- Y10S516/924—Significant dispersive or manipulative operation or step in making or stabilizing colloid system
- Y10S516/928—Mixing combined with non-mixing operation or step, successively or simultaneously, e.g. heating, cooling, ph change, ageing, milling
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Acoustics & Sound (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Saccharide Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919107628A GB9107628D0 (en) | 1991-04-10 | 1991-04-10 | Preparation of diagnostic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE290405T1 true ATE290405T1 (de) | 2005-03-15 |
Family
ID=10693031
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95110723T ATE246519T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostischen mitteln |
| AT92303236T ATE194082T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung diagnostischer mittel |
| AT99203198T ATE290405T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostica |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95110723T ATE246519T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung von diagnostischen mitteln |
| AT92303236T ATE194082T1 (de) | 1991-04-10 | 1992-04-10 | Verfahren zur herstellung diagnostischer mittel |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US5518709A (de) |
| EP (6) | EP0512693B1 (de) |
| JP (2) | JP2865866B2 (de) |
| KR (1) | KR0129861B1 (de) |
| CN (1) | CN1066977A (de) |
| AT (3) | ATE246519T1 (de) |
| AU (2) | AU655016B2 (de) |
| CA (1) | CA2083260A1 (de) |
| DE (3) | DE69231195T2 (de) |
| DK (3) | DK0972526T3 (de) |
| ES (3) | ES2150908T3 (de) |
| FI (1) | FI925600L (de) |
| GB (2) | GB9107628D0 (de) |
| GR (1) | GR3034462T3 (de) |
| HK (1) | HK1006538A1 (de) |
| HU (1) | HUT62805A (de) |
| IE (1) | IE921140A1 (de) |
| IL (2) | IL101564A (de) |
| MX (1) | MX9201694A (de) |
| NZ (1) | NZ242328A (de) |
| PT (2) | PT512693E (de) |
| RU (1) | RU2109521C1 (de) |
| WO (1) | WO1992018164A1 (de) |
| ZA (1) | ZA922636B (de) |
Families Citing this family (196)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613306B1 (en) | 1990-04-02 | 2003-09-02 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
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| US6989141B2 (en) | 1990-05-18 | 2006-01-24 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| USRE39146E1 (en) | 1990-04-02 | 2006-06-27 | Bracco International B.V. | Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof |
| US7083778B2 (en) | 1991-05-03 | 2006-08-01 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
| US5445813A (en) | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
| US6391343B1 (en) | 1991-01-15 | 2002-05-21 | Hemosphere, Inc. | Fibrinogen-coated particles for therapeutic use |
| US5993805A (en) | 1991-04-10 | 1999-11-30 | Quadrant Healthcare (Uk) Limited | Spray-dried microparticles and their use as therapeutic vehicles |
| GB9107628D0 (en) * | 1991-04-10 | 1991-05-29 | Moonbrook Limited | Preparation of diagnostic agents |
| IL104084A (en) | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| DE69332105T2 (de) * | 1992-09-29 | 2003-03-06 | Inhale Therapeutic Systems, San Carlos | Pulmonale abgabe von aktiven fragmenten des parathormons |
| GB9221329D0 (en) | 1992-10-10 | 1992-11-25 | Delta Biotechnology Ltd | Preparation of further diagnostic agents |
| US7425543B2 (en) * | 1992-11-16 | 2008-09-16 | The Corporation Of Mercer University | Microencapsulated materials and method of making same |
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| US20030113273A1 (en) * | 1996-06-17 | 2003-06-19 | Patton John S. | Methods and compositions for pulmonary delivery of insulin |
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| EP0748213B1 (de) | 1994-03-07 | 2004-04-14 | Nektar Therapeutics | Verfahren und mittel zur verabreichung von insulin über die lunge |
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| GB9423419D0 (en) | 1994-11-19 | 1995-01-11 | Andaris Ltd | Preparation of hollow microcapsules |
| US5955108A (en) | 1994-12-16 | 1999-09-21 | Quadrant Healthcare (Uk) Limited | Cross-linked microparticles and their use as therapeutic vehicles |
| US6017310A (en) | 1996-09-07 | 2000-01-25 | Andaris Limited | Use of hollow microcapsules |
| WO1998017318A1 (en) | 1996-10-19 | 1998-04-30 | Quadrant Healthcare (Uk) Limited | Use of hollow microcapsules in diagnosis and therapy |
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1991
- 1991-04-10 GB GB919107628A patent/GB9107628D0/en active Pending
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1992
- 1992-04-09 IE IE114092A patent/IE921140A1/en unknown
- 1992-04-10 AT AT95110723T patent/ATE246519T1/de not_active IP Right Cessation
- 1992-04-10 EP EP92303236A patent/EP0512693B1/de not_active Expired - Lifetime
- 1992-04-10 HU HU9203891A patent/HUT62805A/hu unknown
- 1992-04-10 MX MX9201694A patent/MX9201694A/es unknown
- 1992-04-10 CN CN92103376A patent/CN1066977A/zh active Pending
- 1992-04-10 HK HK98105577A patent/HK1006538A1/xx not_active IP Right Cessation
- 1992-04-10 EP EP99203198A patent/EP0972526B1/de not_active Revoked
- 1992-04-10 ES ES92303236T patent/ES2150908T3/es not_active Expired - Lifetime
- 1992-04-10 DE DE69231195T patent/DE69231195T2/de not_active Expired - Fee Related
- 1992-04-10 US US07/956,875 patent/US5518709A/en not_active Expired - Lifetime
- 1992-04-10 ZA ZA922636A patent/ZA922636B/xx unknown
- 1992-04-10 PT PT92303236T patent/PT512693E/pt unknown
- 1992-04-10 CA CA002083260A patent/CA2083260A1/en not_active Abandoned
- 1992-04-10 EP EP92908598A patent/EP0533886A1/de active Pending
- 1992-04-10 DK DK99203198T patent/DK0972526T3/da active
- 1992-04-10 AU AU15891/92A patent/AU655016B2/en not_active Ceased
- 1992-04-10 WO PCT/GB1992/000643 patent/WO1992018164A1/en not_active Ceased
- 1992-04-10 DK DK92303236T patent/DK0512693T3/da active
- 1992-04-10 EP EP07075443A patent/EP1829557A3/de not_active Withdrawn
- 1992-04-10 DE DE69233489T patent/DE69233489T2/de not_active Expired - Fee Related
- 1992-04-10 KR KR1019920703116A patent/KR0129861B1/ko not_active Expired - Fee Related
- 1992-04-10 ES ES99203198T patent/ES2242355T3/es not_active Expired - Lifetime
- 1992-04-10 JP JP4508032A patent/JP2865866B2/ja not_active Expired - Fee Related
- 1992-04-10 EP EP05075544A patent/EP1547619A3/de not_active Withdrawn
- 1992-04-10 DE DE69233148T patent/DE69233148T2/de not_active Expired - Fee Related
- 1992-04-10 IL IL10156492A patent/IL101564A/en not_active IP Right Cessation
- 1992-04-10 FI FI925600A patent/FI925600L/fi unknown
- 1992-04-10 NZ NZ242328A patent/NZ242328A/en not_active IP Right Cessation
- 1992-04-10 EP EP95110723A patent/EP0681843B2/de not_active Expired - Lifetime
- 1992-04-10 PT PT95110723T patent/PT681843E/pt unknown
- 1992-04-10 ES ES95110723T patent/ES2203626T3/es not_active Expired - Lifetime
- 1992-04-10 AT AT92303236T patent/ATE194082T1/de not_active IP Right Cessation
- 1992-04-10 AT AT99203198T patent/ATE290405T1/de not_active IP Right Cessation
- 1992-04-10 DK DK95110723T patent/DK0681843T3/da active
- 1992-10-29 RU RU92016571A patent/RU2109521C1/ru active
- 1992-12-09 GB GB9225716A patent/GB2260745B/en not_active Expired - Fee Related
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1994
- 1994-10-07 AU AU74483/94A patent/AU691196B2/en not_active Ceased
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1995
- 1995-08-22 US US08/517,590 patent/US6022525A/en not_active Expired - Fee Related
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1998
- 1998-01-23 IL IL12303898A patent/IL123038A0/xx unknown
- 1998-08-19 JP JP10233181A patent/JPH11128232A/ja active Pending
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1999
- 1999-09-28 US US09/407,370 patent/US6569405B1/en not_active Expired - Fee Related
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2000
- 2000-09-21 GR GR20000402151T patent/GR3034462T3/el not_active IP Right Cessation
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