ATE290860T1 - Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren - Google Patents

Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren

Info

Publication number
ATE290860T1
ATE290860T1 AT95928721T AT95928721T ATE290860T1 AT E290860 T1 ATE290860 T1 AT E290860T1 AT 95928721 T AT95928721 T AT 95928721T AT 95928721 T AT95928721 T AT 95928721T AT E290860 T1 ATE290860 T1 AT E290860T1
Authority
AT
Austria
Prior art keywords
reservoirs
biodegradable
devices
agent
solid tumors
Prior art date
Application number
AT95928721T
Other languages
English (en)
Inventor
Henry Brem
Robert J Langer
Abraham J Domb
Original Assignee
Massachusetts Inst Technology
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23089835&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE290860(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Massachusetts Inst Technology, Univ Johns Hopkins filed Critical Massachusetts Inst Technology
Application granted granted Critical
Publication of ATE290860T1 publication Critical patent/ATE290860T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95928721T 1994-08-02 1995-08-02 Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren ATE290860T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/284,341 US5626862A (en) 1994-08-02 1994-08-02 Controlled local delivery of chemotherapeutic agents for treating solid tumors
PCT/US1995/009805 WO1996003984A1 (en) 1994-08-02 1995-08-02 Controlled local delivery of chemotherapeutic agents for treating solid tumors

Publications (1)

Publication Number Publication Date
ATE290860T1 true ATE290860T1 (de) 2005-04-15

Family

ID=23089835

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95928721T ATE290860T1 (de) 1994-08-02 1995-08-02 Kontrollierte, lokale verabreichung von chemotherapeutischen wirkstoffen zur behandlung von festen tumoren

Country Status (9)

Country Link
US (4) US5626862A (de)
EP (1) EP0774964B1 (de)
JP (1) JPH10505587A (de)
AT (1) ATE290860T1 (de)
CA (1) CA2196304C (de)
DE (1) DE69534080T2 (de)
ES (1) ES2243940T3 (de)
PT (1) PT774964E (de)
WO (1) WO1996003984A1 (de)

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CA2196304C (en) 2011-02-15
CA2196304A1 (en) 1996-02-15
US5626862A (en) 1997-05-06
ES2243940T3 (es) 2005-12-01
US5846565A (en) 1998-12-08
JPH10505587A (ja) 1998-06-02
DE69534080T2 (de) 2006-04-13
US5651986A (en) 1997-07-29
PT774964E (pt) 2005-08-31
WO1996003984A1 (en) 1996-02-15
USRE37410E1 (en) 2001-10-16
EP0774964B1 (de) 2005-03-16
DE69534080D1 (de) 2005-04-21

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