ATE291910T1 - Verwendung von coenzym q (ubiquinone) und eikosapentaensäure (epa) für die behandlung von non-hodgkin's lymphoma und psychiatrischen oder neurologischen erkrankungen - Google Patents
Verwendung von coenzym q (ubiquinone) und eikosapentaensäure (epa) für die behandlung von non-hodgkin's lymphoma und psychiatrischen oder neurologischen erkrankungenInfo
- Publication number
- ATE291910T1 ATE291910T1 AT02724475T AT02724475T ATE291910T1 AT E291910 T1 ATE291910 T1 AT E291910T1 AT 02724475 T AT02724475 T AT 02724475T AT 02724475 T AT02724475 T AT 02724475T AT E291910 T1 ATE291910 T1 AT E291910T1
- Authority
- AT
- Austria
- Prior art keywords
- acid
- ubiquinone
- coenzyme
- psychiatric
- epa
- Prior art date
Links
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 3
- 235000017471 coenzyme Q10 Nutrition 0.000 title abstract 3
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 2
- NPCOQXAVBJJZBQ-UHFFFAOYSA-N reduced coenzyme Q9 Natural products COC1=C(O)C(C)=C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)C(O)=C1OC NPCOQXAVBJJZBQ-UHFFFAOYSA-N 0.000 title abstract 2
- 229940035936 ubiquinone Drugs 0.000 title abstract 2
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 239000005515 coenzyme Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000000926 neurological effect Effects 0.000 title 1
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 2
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 abstract 2
- HOBAELRKJCKHQD-UHFFFAOYSA-N (8Z,11Z,14Z)-8,11,14-eicosatrienoic acid Natural products CCCCCC=CCC=CCC=CCCCCCCC(O)=O HOBAELRKJCKHQD-UHFFFAOYSA-N 0.000 abstract 1
- 235000021298 Dihomo-γ-linolenic acid Nutrition 0.000 abstract 1
- OPGOLNDOMSBSCW-CLNHMMGSSA-N Fursultiamine hydrochloride Chemical compound Cl.C1CCOC1CSSC(\CCO)=C(/C)N(C=O)CC1=CN=C(C)N=C1N OPGOLNDOMSBSCW-CLNHMMGSSA-N 0.000 abstract 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 abstract 1
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 abstract 1
- 235000021342 arachidonic acid Nutrition 0.000 abstract 1
- 229940114079 arachidonic acid Drugs 0.000 abstract 1
- 238000011260 co-administration Methods 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- HOBAELRKJCKHQD-QNEBEIHSSA-N dihomo-γ-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCCCC(O)=O HOBAELRKJCKHQD-QNEBEIHSSA-N 0.000 abstract 1
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 1
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 abstract 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 abstract 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 abstract 1
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 abstract 1
- 235000020664 gamma-linolenic acid Nutrition 0.000 abstract 1
- 229960002733 gamolenic acid Drugs 0.000 abstract 1
- 235000020778 linoleic acid Nutrition 0.000 abstract 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 abstract 1
- JIWBIWFOSCKQMA-UHFFFAOYSA-N stearidonic acid Natural products CCC=CCC=CCC=CCC=CCCCCC(O)=O JIWBIWFOSCKQMA-UHFFFAOYSA-N 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Addiction (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0113104A GB0113104D0 (en) | 2001-05-30 | 2001-05-30 | Coenzyme Q and EPA |
| GB0123446A GB0123446D0 (en) | 2001-09-28 | 2001-09-28 | Coenzyme Q and EPA |
| PCT/GB2002/002148 WO2002096408A1 (en) | 2001-05-30 | 2002-05-09 | Coenzyme q and eicosapentaenoic acid (epa) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE291910T1 true ATE291910T1 (de) | 2005-04-15 |
Family
ID=26246133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02724475T ATE291910T1 (de) | 2001-05-30 | 2002-05-09 | Verwendung von coenzym q (ubiquinone) und eikosapentaensäure (epa) für die behandlung von non-hodgkin's lymphoma und psychiatrischen oder neurologischen erkrankungen |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US20020198177A1 (de) |
| EP (1) | EP1390025B1 (de) |
| JP (1) | JP2004531568A (de) |
| KR (1) | KR20040004652A (de) |
| CN (1) | CN1268328C (de) |
| AT (1) | ATE291910T1 (de) |
| BR (1) | BR0209749A (de) |
| CA (1) | CA2449199A1 (de) |
| CZ (1) | CZ299784B6 (de) |
| DE (1) | DE60203494T2 (de) |
| EE (1) | EE200300599A (de) |
| ES (1) | ES2238568T3 (de) |
| HR (1) | HRP20030988A2 (de) |
| HU (1) | HUP0401343A3 (de) |
| IL (2) | IL159038A0 (de) |
| IS (1) | IS7005A (de) |
| MX (1) | MXPA03010888A (de) |
| NO (1) | NO20035281L (de) |
| NZ (1) | NZ529339A (de) |
| PL (1) | PL364093A1 (de) |
| PT (1) | PT1390025E (de) |
| RU (1) | RU2003133142A (de) |
| SK (1) | SK14502003A3 (de) |
| WO (1) | WO2002096408A1 (de) |
Families Citing this family (117)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901809D0 (en) * | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
| JP4859314B2 (ja) * | 2001-09-26 | 2012-01-25 | 株式会社カネカ | 潰瘍性大腸炎および/又はクローン病治療剤 |
| NL1019368C2 (nl) * | 2001-11-14 | 2003-05-20 | Nutricia Nv | Preparaat voor het verbeteren van receptorwerking. |
| US6974592B2 (en) | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
| BRPI0315977B8 (pt) | 2002-11-04 | 2021-05-25 | Dsm Nutritional Products Ag | microcápsulas possuindo múltiplas cascas e método para preparação destas |
| CN1294825C (zh) * | 2003-03-25 | 2007-01-17 | 汕头市金园区丹味食品发展中心 | 一种营养粉及其制备方法 |
| GB0311081D0 (en) | 2003-05-14 | 2003-06-18 | Btg Internat Limted | Treatment of neurodegenerative conditions |
| EP2324828A1 (de) | 2003-08-18 | 2011-05-25 | BTG International Limited | Behandlung neurodegenerativer Erkrankungen |
| WO2005046668A1 (ja) * | 2003-11-14 | 2005-05-26 | Mochida Pharmaceutical Co., Ltd. | 言語障害予防・治療剤 |
| EP1713463A4 (de) * | 2004-01-19 | 2009-03-18 | Martek Biosciences Corp | Reelin-mangel oder dysfunktion und relevante verfahren |
| HRP20130459T1 (en) | 2004-01-22 | 2013-06-30 | University Of Miami | Topical co-enzyme q10 formulations and methods of use |
| ZA200607794B (en) * | 2004-04-16 | 2008-05-28 | Solvay Pharm Gmbh | Essential fatty acids in the prevention and/or treatment of depression in patients with coronary heart or artery disease |
| ES2247939B1 (es) * | 2004-08-19 | 2007-04-01 | Fernando Jose Garcia Fructuoso | Suplemento alimenticio basado en la utilizacion de acidos grasos omega-3 (dha-epa) para el tratamiento del sindrome de fatiga cronica. |
| CN1319534C (zh) * | 2004-10-28 | 2007-06-06 | 昆明翔昊科技有限公司 | 含番茄红素和辅酶q10的制剂及其制备方法 |
| GB2421909A (en) * | 2004-12-23 | 2006-07-12 | Laxdale Ltd | Pharmaceutical compositions comprising EPA and methods of use |
| CA2596023A1 (en) | 2005-01-27 | 2006-11-09 | Ocean Nutrition Canada Ltd. | Fatty acid-benzenediol derivatives and methods of making and using thereof |
| GB0504362D0 (en) | 2005-03-02 | 2005-04-06 | Btg Int Ltd | Cytokine modulators |
| RU2429851C2 (ru) * | 2005-05-23 | 2011-09-27 | Массачусетс Инститьют Оф Текнолоджи | Композиции, содержащие pufa и/или уридин, и способы их применения |
| US9968120B2 (en) | 2006-05-17 | 2018-05-15 | Dsm Nutritional Products Ag | Homogenized formulations containing microcapsules and methods of making and using thereof |
| US7838526B2 (en) * | 2005-08-05 | 2010-11-23 | Esther Baldinger | Method of treating neurological disorders |
| GB0604647D0 (en) * | 2006-03-08 | 2006-04-19 | Shchepinov Mikhail | Stabilized food supplements and their derivatives |
| JP2009536215A (ja) * | 2006-05-02 | 2009-10-08 | ユニバーシティ オブ マイアミ | 局所コエンザイムq10製剤、及び疼痛、疲労、並びに創傷の治療 |
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| US4273763A (en) * | 1978-01-23 | 1981-06-16 | Efamol Limited | Pharmaceutical and dietary compositions |
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| GB9403855D0 (en) * | 1994-03-01 | 1994-04-20 | Scotia Holdings Plc | Fatty acid derivatives |
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2002
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- 2002-05-09 DE DE60203494T patent/DE60203494T2/de not_active Expired - Fee Related
- 2002-05-09 EE EEP200300599A patent/EE200300599A/xx unknown
- 2002-05-09 KR KR10-2003-7015381A patent/KR20040004652A/ko not_active Withdrawn
- 2002-05-09 CN CNB028110110A patent/CN1268328C/zh not_active Expired - Fee Related
- 2002-05-09 WO PCT/GB2002/002148 patent/WO2002096408A1/en not_active Ceased
- 2002-05-09 PT PT02724475T patent/PT1390025E/pt unknown
- 2002-05-09 BR BR0209749-4A patent/BR0209749A/pt not_active IP Right Cessation
- 2002-05-09 PL PL02364093A patent/PL364093A1/xx not_active Application Discontinuation
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- 2002-05-09 CA CA002449199A patent/CA2449199A1/en not_active Abandoned
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- 2002-05-09 JP JP2002592918A patent/JP2004531568A/ja active Pending
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| CA2449199A1 (en) | 2002-12-05 |
| KR20040004652A (ko) | 2004-01-13 |
| HRP20030988A2 (en) | 2004-06-30 |
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| MXPA03010888A (es) | 2004-02-27 |
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| US20020198177A1 (en) | 2002-12-26 |
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| HK1058883A1 (en) | 2004-06-11 |
| EP1390025B1 (de) | 2005-03-30 |
| CN1522143A (zh) | 2004-08-18 |
| RU2003133142A (ru) | 2005-04-20 |
| BR0209749A (pt) | 2004-07-27 |
| WO2002096408A1 (en) | 2002-12-05 |
| EP1390025A1 (de) | 2004-02-25 |
| CN1268328C (zh) | 2006-08-09 |
| HUP0401343A3 (en) | 2008-08-28 |
| PT1390025E (pt) | 2005-08-31 |
| DE60203494D1 (de) | 2005-05-04 |
| NO20035281D0 (no) | 2003-11-27 |
| NO20035281L (no) | 2003-11-27 |
| CZ299784B6 (cs) | 2008-11-26 |
| HUP0401343A2 (hu) | 2004-11-29 |
| EE200300599A (et) | 2004-02-16 |
| IL159038A0 (en) | 2004-05-12 |
| SK14502003A3 (en) | 2004-10-05 |
| NZ529339A (en) | 2004-08-27 |
| PL364093A1 (en) | 2004-12-13 |
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