ATE292678T1 - Klonierung und rekombinante herstellung von polistinae venom-enzymen, beispielsweise phospholipase und hyaluronidase, und immunologische therapien davon abgeleitet - Google Patents

Klonierung und rekombinante herstellung von polistinae venom-enzymen, beispielsweise phospholipase und hyaluronidase, und immunologische therapien davon abgeleitet

Info

Publication number
ATE292678T1
ATE292678T1 AT99950198T AT99950198T ATE292678T1 AT E292678 T1 ATE292678 T1 AT E292678T1 AT 99950198 T AT99950198 T AT 99950198T AT 99950198 T AT99950198 T AT 99950198T AT E292678 T1 ATE292678 T1 AT E292678T1
Authority
AT
Austria
Prior art keywords
polistinae venom
hyaluronidase
cloning
recombinant production
enzymes
Prior art date
Application number
AT99950198T
Other languages
English (en)
Inventor
Te Paio King
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Application granted granted Critical
Publication of ATE292678T1 publication Critical patent/ATE292678T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT99950198T 1998-10-01 1999-10-01 Klonierung und rekombinante herstellung von polistinae venom-enzymen, beispielsweise phospholipase und hyaluronidase, und immunologische therapien davon abgeleitet ATE292678T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/166,205 US6372471B1 (en) 1998-10-01 1998-10-01 Cloning and recombinant production of vespid venom enzymes, such as phospholipase and hyaluronidase, and immunological therapies based thereon
PCT/US1999/023211 WO2000018896A1 (en) 1998-10-01 1999-10-01 Cloning and recombinant production of polistinae venom enzymes, such as phospholipase and hyaluronidase, and immunological therapies based thereon

Publications (1)

Publication Number Publication Date
ATE292678T1 true ATE292678T1 (de) 2005-04-15

Family

ID=22602254

Family Applications (2)

Application Number Title Priority Date Filing Date
AT99950198T ATE292678T1 (de) 1998-10-01 1999-10-01 Klonierung und rekombinante herstellung von polistinae venom-enzymen, beispielsweise phospholipase und hyaluronidase, und immunologische therapien davon abgeleitet
AT05001983T ATE346143T1 (de) 1998-10-01 1999-10-01 Klonierung und rekombinante herstellung von polistinae insektengift- enzymen, beispielsweise hyaluronidase, und davon abgeleitete immunologische therapien

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05001983T ATE346143T1 (de) 1998-10-01 1999-10-01 Klonierung und rekombinante herstellung von polistinae insektengift- enzymen, beispielsweise hyaluronidase, und davon abgeleitete immunologische therapien

Country Status (11)

Country Link
US (3) US6372471B1 (de)
EP (2) EP1117769B1 (de)
JP (1) JP2002525107A (de)
AT (2) ATE292678T1 (de)
AU (1) AU760812B2 (de)
CA (1) CA2344578A1 (de)
DE (2) DE69934150T2 (de)
DK (1) DK1528102T3 (de)
ES (2) ES2280059T3 (de)
PT (1) PT1117769E (de)
WO (1) WO2000018896A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2543072A1 (en) * 2003-11-05 2005-06-02 Pevion Biotech Ltd. Compositions comprising melittin-derived peptides and methods for the potentiation of immune responses against target antigens

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK82892D0 (da) 1992-06-24 1992-06-24 Michael Hansen Anvendelse af braadgifte fra bier og hvepse til fremstilling af laegemidler til behandling af infektioner
US5593877A (en) 1993-03-11 1997-01-14 The Rockefeller University Nucleic acid and recombinant production of vespid venom hyaluronidase

Also Published As

Publication number Publication date
CA2344578A1 (en) 2000-04-06
US7060265B2 (en) 2006-06-13
DK1528102T3 (da) 2007-03-26
DE69934150T2 (de) 2007-10-11
ATE346143T1 (de) 2006-12-15
EP1528102B1 (de) 2006-11-22
EP1528102B9 (de) 2007-12-12
ES2239853T3 (es) 2005-10-01
EP1528102A2 (de) 2005-05-04
US6372471B1 (en) 2002-04-16
DE69924628D1 (de) 2005-05-12
EP1528102A3 (de) 2005-10-26
DE69924628T2 (de) 2006-02-09
EP1117769A1 (de) 2001-07-25
JP2002525107A (ja) 2002-08-13
AU6290699A (en) 2000-04-17
WO2000018896A1 (en) 2000-04-06
AU760812B2 (en) 2003-05-22
US6652851B1 (en) 2003-11-25
EP1117769B1 (de) 2005-04-06
PT1117769E (pt) 2005-08-31
US20040175393A1 (en) 2004-09-09
ES2280059T3 (es) 2007-09-01
DE69934150D1 (de) 2007-01-04

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