ATE292957T1 - Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung - Google Patents

Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung

Info

Publication number
ATE292957T1
ATE292957T1 AT01906803T AT01906803T ATE292957T1 AT E292957 T1 ATE292957 T1 AT E292957T1 AT 01906803 T AT01906803 T AT 01906803T AT 01906803 T AT01906803 T AT 01906803T AT E292957 T1 ATE292957 T1 AT E292957T1
Authority
AT
Austria
Prior art keywords
supersaturated solution
liposomes containing
enclosed compound
compound
enclosed
Prior art date
Application number
AT01906803T
Other languages
English (en)
Inventor
Robert M Abra
Yechezkel Barenholz
Danilo D Lasic
Tal Peleg-Schulman
Original Assignee
Alza Corp
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp, Yissum Res Dev Co filed Critical Alza Corp
Application granted granted Critical
Publication of ATE292957T1 publication Critical patent/ATE292957T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT01906803T 2000-01-28 2001-01-26 Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung ATE292957T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17865000P 2000-01-28 2000-01-28
PCT/US2001/003063 WO2001054666A1 (en) 2000-01-28 2001-01-26 Liposomes containing an entrapped compound in supersaturated solution

Publications (1)

Publication Number Publication Date
ATE292957T1 true ATE292957T1 (de) 2005-04-15

Family

ID=22653355

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01906803T ATE292957T1 (de) 2000-01-28 2001-01-26 Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung

Country Status (19)

Country Link
US (2) US20010033861A1 (de)
EP (1) EP1274399B1 (de)
JP (1) JP2003521366A (de)
KR (2) KR20070089761A (de)
CN (1) CN1236760C (de)
AT (1) ATE292957T1 (de)
AU (2) AU3467001A (de)
CA (1) CA2398514A1 (de)
DE (1) DE60110057T2 (de)
DK (1) DK1274399T3 (de)
ES (1) ES2236181T3 (de)
HU (1) HUP0400628A3 (de)
IL (2) IL150483A0 (de)
MX (1) MXPA02007320A (de)
NO (1) NO20023139L (de)
NZ (1) NZ519856A (de)
PT (1) PT1274399E (de)
WO (1) WO2001054666A1 (de)
ZA (1) ZA200205468B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1465590B1 (de) * 2001-11-02 2008-03-26 The Governors Of The University Of Alberta Micelle-zusammensetzungen enthaltend pegylierten phospholipide und einen photosensibilisator
JP2005530704A (ja) * 2002-03-05 2005-10-13 トランセイブ， インク． 細胞内感染を予防及び治療するための吸入システム
US20040161481A1 (en) * 2002-12-18 2004-08-19 Algorx Administration of capsaicinoids
MXPA05006670A (es) * 2002-12-18 2005-10-19 Algorx Pharmaceuticals Inc Administracion de capsaicinoides.
US8980310B2 (en) * 2002-12-31 2015-03-17 Bharat Serums and Vaccines, Ltd. Non-pegylated long-circulating liposomes
AU2004233873B2 (en) 2003-04-25 2010-11-18 The Penn State Research Foundation Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
US20100034874A1 (en) * 2006-12-08 2010-02-11 Katayama Chemical Industries Co., Ltd. Liposome encapsulating ammine-platinum complex at high concentration, and method for production of the liposome
US8158682B2 (en) * 2008-09-12 2012-04-17 Vallinex, Inc. Instillation administration of capsaicinoids for the treatment of pain
JP5983608B2 (ja) * 2011-07-15 2016-09-06 コニカミノルタ株式会社 溶解助剤を利用したリポソーム含有製剤およびその製造方法
US9849087B2 (en) 2011-11-08 2017-12-26 The Board Of Trustees Of The University Of Arkansas Methods and compositions for X-ray induced release from pH sensitive liposomes
RU2014133467A (ru) 2012-02-17 2016-04-10 Селшн Корпорейшн Термочувствительные составы в виде наночастиц и способ их получения
US10039716B2 (en) * 2013-03-13 2018-08-07 Mallinckrodt Llc Liposomal cisplatin compositions for cancer therapy
CA2943049A1 (en) 2014-04-08 2015-10-15 Aradigm Corporation Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria
WO2015156904A1 (en) * 2014-04-08 2015-10-15 Aradigm Corporation Liposomes that form drug nanocrystals after freeze-thaw
US20160120806A1 (en) * 2014-04-08 2016-05-05 Aradigm Corporation Nanocrystals formed in a microenvironment
WO2015166081A1 (en) 2014-04-30 2015-11-05 Encapson B.V. Medical devices with non-uniform coatings for enhanced echogenicity
HK1258650A1 (zh) * 2015-09-14 2019-11-15 Vgsk Technologies, Inc. 皮下、舌下和口服治疗用空间稳定载体、用於治疗哺乳动物的组合物和方法
DE102017210700A1 (de) 2017-06-26 2018-12-27 Robert Bosch Gmbh Verfahren zum automatisierten Quantifizieren eines Analyten sowie NMR-Messgerät zur Durchführung des Verfahrens
US10925831B2 (en) * 2017-08-28 2021-02-23 Wake Forest University Liposomal formulations of platinum-acridine anticancer agents and methods thereof
WO2022235907A1 (en) 2021-05-05 2022-11-10 Vgsk Technologies, Inc. Liposome-encapsulated corticosteriods inhibit sars-cov-2 replication and reduces lung inflammation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3576117D1 (de) 1984-09-24 1990-04-05 Michael Mezei Mehrphasige pharmazeutische zusammensetzung.
US5013556A (en) * 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
DE69107844T2 (de) * 1990-04-18 1995-08-10 Takeda Chemical Industries, Ltd., Osaka Liposomenzusammensetzung.
EP0551169A1 (de) * 1992-01-10 1993-07-14 Takeda Chemical Industries, Ltd. Liposomzusammensetzung und Verfahren
US5395619A (en) * 1993-03-03 1995-03-07 Liposome Technology, Inc. Lipid-polymer conjugates and liposomes
ATE220893T1 (de) * 1996-08-21 2002-08-15 Childrens Hosp Medical Center Hautaufhellungszusammensetzungen
ATE252372T1 (de) * 1996-08-23 2003-11-15 Sequus Pharm Inc Liposome enthaltend cisplatin
TW520297B (en) * 1996-10-11 2003-02-11 Sequus Pharm Inc Fusogenic liposome composition and method
CA2269758C (en) * 1996-10-22 2008-01-08 Hermes Biosciences, Inc. Liposome compositions comprising ionizable compounds in stable precipitated form and methods for their preparation
WO2001025223A1 (en) * 1999-10-06 2001-04-12 The Research Foundation Of State University Of New York Stabilization of taxane-containing dispersed systems
CZ20022410A3 (cs) * 2000-01-31 2003-08-13 Pfizer Products Inc. Benzoanelované heterocyklylové deriváty nikotinamidu užitečné jako selektivní inhibitory isozymů PDE4

Also Published As

Publication number Publication date
DE60110057D1 (de) 2005-05-19
US20060159739A1 (en) 2006-07-20
KR20070089761A (ko) 2007-08-31
KR20030011767A (ko) 2003-02-11
EP1274399B1 (de) 2005-04-13
DK1274399T3 (da) 2005-08-08
US20010033861A1 (en) 2001-10-25
CN1236760C (zh) 2006-01-18
DE60110057T2 (de) 2005-09-08
NO20023139L (no) 2002-09-23
AU2001234670B2 (en) 2005-05-19
IL150483A0 (en) 2002-12-01
KR100782891B1 (ko) 2007-12-06
PT1274399E (pt) 2005-07-29
US8062662B2 (en) 2011-11-22
CN1396822A (zh) 2003-02-12
ES2236181T3 (es) 2005-07-16
ZA200205468B (en) 2004-09-29
JP2003521366A (ja) 2003-07-15
HUP0400628A2 (hu) 2004-06-28
AU3467001A (en) 2001-08-07
IL150483A (en) 2008-07-08
NO20023139D0 (no) 2002-06-28
CA2398514A1 (en) 2001-08-02
NZ519856A (en) 2004-03-26
MXPA02007320A (es) 2004-07-30
HUP0400628A3 (en) 2006-07-28
WO2001054666A1 (en) 2001-08-02
EP1274399A1 (de) 2003-01-15

Similar Documents

Publication Publication Date Title
ATE292957T1 (de) Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung
EP1073466A4 (de) Nikotin enthaltende lösung
DE69608397D1 (de) Liposomenhaltige Tintenzusammensetzungen
FI964083A7 (fi) Fusogeeniset liposomit ja menetelmät valmistaa ja käyttää niitä
NO20010791D0 (no) Forseglet beholder
EE200100018A (et) Propoksilaati sisaldavad kütusesegud
IT1292309B1 (it) Involucro per bobina e bobina di macchina per cucire.
AU8260701A (en) Solution preparations stabilized over long time
TR199902251A3 (tr) Dogal kakao aromali/çesnili bilesimler ve bunlari hazirlama yöntemleri.
HUP0301211A3 (en) Haemostatically active preparation containing vwf and method for the production thereof
AU2001263835A1 (en) Haemostatically active preparation containing vWF and method for the production thereof
FI971743A7 (fi) Liposomikoostumus, joka sisältää selegiliiniä
AU2001260270A1 (en) Liposomes containing active substances
ATE345778T1 (de) (ester)-lysolecithine in liposomen
EE05192B1 (et) Trptamiini derivaadid ja analoogsed hendid ning neid sisaldavad farmatseutilised preparaadid
ITBO20000361A0 (it) Metodo e macchina per l'incarto di sigari .
EE04701B1 (et) Kihisevad preparaadid
ITTO20010028A0 (it) Metodo per aumentare l'attivita' antitumorale di una sostanza contenente amigdalina, composizione contenente una sostanza con contenuto aume
IT1303173B1 (it) Macchina per la formatura di avvolgimenti per statori di macchinedinamo-elettriche e procedimento di formatura realizzato mediante
EA200100269A1 (ru) Иммуногенные липосомные композиции
DE3483500D1 (de) Oeliges gemisch, aclarubicin bzw. dessen hydrochlorid enthaltend.
FI980016A0 (fi) Foerfarande foer att reservera dataoeverfoeringskanaler mellan ett basstationssystem och en mobiltelefoncentral
GB9910748D0 (en) Magnetising magnet
KR950031407U (ko) 4폴 마그네트
ES2171255T3 (es) Nuevos compuestos intermedios para plaguicidas.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1274399

Country of ref document: EP

REN Ceased due to non-payment of the annual fee