|
US6432448B1
(en)
*
|
1999-02-08 |
2002-08-13 |
Fmc Corporation |
Edible coating composition
|
|
US6723342B1
(en)
|
1999-02-08 |
2004-04-20 |
Fmc Corporation |
Edible coating composition
|
|
US6932861B2
(en)
|
2000-11-28 |
2005-08-23 |
Fmc Corporation |
Edible PGA coating composition
|
|
BR0115585A
(pt)
|
2000-11-28 |
2005-12-13 |
Fmc Corp |
Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento
|
|
FR2830447B1
(fr)
*
|
2001-10-09 |
2004-04-16 |
Flamel Tech Sa |
Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
|
|
US8101209B2
(en)
|
2001-10-09 |
2012-01-24 |
Flamel Technologies |
Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
|
|
JP4698950B2
(ja)
|
2002-04-09 |
2011-06-08 |
フラメル・テクノロジー |
アモキシシリンの改変された放出のための、マイクロカプセルの水性懸濁液形態での経口医薬品製剤
|
|
EP1492511B3
(de)
|
2002-04-09 |
2012-05-02 |
Flamel Technologies |
Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
|
|
US20030220351A1
(en)
*
|
2002-05-24 |
2003-11-27 |
Gilbert Gonzales |
Enteric coated caffeine tablet
|
|
EP1607087A1
(de)
*
|
2003-03-27 |
2005-12-21 |
Hisamitsu Pharmaceutical Co., Inc. |
Medizinische, oral einzunehmende präparate zur abgabe im dickdarm, medizinische, oral einzunehmende präparate zur behandlung von dickdarmkrebs und medizinische, oral einzunehmende präparate zur behandlung von dickdarmentzündung
|
|
US7737133B2
(en)
|
2003-09-03 |
2010-06-15 |
Agi Therapeutics Ltd. |
Formulations and methods of treating inflammatory bowel disease
|
|
US7825106B2
(en)
|
2003-09-03 |
2010-11-02 |
Agi Therapeutics Ltd. |
Modified release formulations and methods of treating inflammatory bowel disease
|
|
US8709476B2
(en)
|
2003-11-04 |
2014-04-29 |
Supernus Pharmaceuticals, Inc. |
Compositions of quaternary ammonium compounds containing bioavailability enhancers
|
|
DE602004030931D1
(de)
|
2003-11-04 |
2011-02-17 |
Supernus Pharmaceuticals Inc |
|
|
CA2547137A1
(en)
|
2003-11-25 |
2005-06-09 |
Sb Pharmco Puerto Rico Inc. |
Carvedilol free base, salts, anhydrous forms or solvates thereof, corresponding pharmaceutical compositions, controlled release formulations, and treatment or delivery methods
|
|
WO2005074598A2
(en)
|
2004-01-30 |
2005-08-18 |
Johns Hopkins University |
Nitroxyl progenitor compounds and methods of use
|
|
AT500144A1
(de)
*
|
2004-03-05 |
2005-11-15 |
Sanochemia Pharmazeutika Ag |
Tolperison enthaltende, pharmazeutische zubereitung mit steuerbarer wirkstofffreisetzung zur oralen verabreichung
|
|
CA2595116A1
(en)
*
|
2004-04-28 |
2005-11-10 |
Procarrier, Inc. |
Oral formulation for delivery of poorly absorbed drugs
|
|
KR20050104152A
(ko)
*
|
2004-04-28 |
2005-11-02 |
최승호 |
경구용 약물의 흡수를 증진하는 약제학적 조성물
|
|
CA2572223C
(en)
|
2004-06-25 |
2014-08-12 |
The Johns Hopkins University |
Angiogenesis inhibitors
|
|
FR2878159B1
(fr)
*
|
2004-11-24 |
2008-10-17 |
Flamel Technologies Sa |
Medicament oral a liberation modifiee d'au moins un principe actif sous forme multimicrocapsulaire
|
|
US20070129402A1
(en)
*
|
2004-12-27 |
2007-06-07 |
Eisai Research Institute |
Sustained release formulations
|
|
MX2007007836A
(es)
|
2004-12-27 |
2007-08-20 |
Eisai R&D Man Co Ltd |
Metodo para estabilizar un farmaco anti-demencia.
|
|
AU2006275702A1
(en)
|
2005-07-29 |
2007-02-08 |
Concert Pharmaceuticals Inc. |
Novel pharmaceutical compounds
|
|
CA2617150C
(en)
*
|
2005-07-29 |
2016-06-14 |
Government Of The U.S.A., As Represented By The Secretary, Department Of Health And Human Services |
Use of chk2 kinase inhibitors for cancer treatment
|
|
US20070154413A1
(en)
*
|
2005-12-30 |
2007-07-05 |
Nolan Lee Phillips |
Dentifrices comprising biogenic silica materials
|
|
US20070154412A1
(en)
*
|
2005-12-30 |
2007-07-05 |
Nolan Lee Phillips |
Dentifrices comprising biogenic silica materials
|
|
TW200808380A
(en)
*
|
2006-02-21 |
2008-02-16 |
Shinetsu Chemical Co |
Enteric-coated preparation for site-specific delivery of drug to site within the small intestine
|
|
US8030356B2
(en)
|
2006-03-17 |
2011-10-04 |
Cardioxyl Pharmaceuticals, Inc. |
N-hydroxylsulfonamide derivatives as new physiologically useful nitroxyl donors
|
|
US7700651B2
(en)
|
2006-07-19 |
2010-04-20 |
The Board Of Regents Of The University Of Texas System |
Preparations of phospholipids and pharmaceuticals containing 5-amino salicylic acid for the treatment of inflammatory bowel disease
|
|
US20080159968A1
(en)
*
|
2006-12-27 |
2008-07-03 |
Fultz William C |
Dentifrices comprising biogenic silica materials and calcium carbonate
|
|
US20080159967A1
(en)
*
|
2006-12-27 |
2008-07-03 |
Fultz William C |
Dentifrices comprising biogenic silica materials and at least one calcium phosphate
|
|
JP2010516680A
(ja)
|
2007-01-19 |
2010-05-20 |
エックスカバリー,インコーポレイテッド |
キナーゼ阻害薬化合物
|
|
CN104119310B
(zh)
*
|
2007-09-26 |
2017-04-12 |
约翰斯霍普金斯大学 |
作为新的在生理学上可用于硝酰基供体的n‑羟基磺酰胺衍生物及包含其的医药组合物
|
|
EP3067352A3
(de)
|
2008-05-07 |
2016-10-19 |
Cardioxyl Pharmaceuticals Inc. |
Neuartige nitrosoverbindungen als nitroxyldonatoren und verfahren zur verwendung davon
|
|
JP5670325B2
(ja)
|
2008-06-19 |
2015-02-18 |
エックスカバリー ホールディング カンパニー エルエルシー |
キナーゼ阻害化合物としての置換されたピリダジンカルボキサミド化合物
|
|
CN102239149B
(zh)
|
2008-10-06 |
2015-05-13 |
约翰·霍普金斯大学 |
喹啉化合物作为血管新生、人类甲硫氨酰氨肽酶、以及sirt1的抑制剂,以及治疗病症的方法
|
|
EP2255794A1
(de)
|
2009-05-29 |
2010-12-01 |
H e x a l Aktiengesellschaft |
Magensaftresistenter Überzug
|
|
US20120093904A1
(en)
*
|
2009-07-30 |
2012-04-19 |
Evonik Roehm Gmbh |
Composition comprising an anionic polymeric material and the salt of a saturated monocarboxylic acid having 6 to 22 carbon atoms
|
|
US20110160200A1
(en)
*
|
2009-11-23 |
2011-06-30 |
Cardioxyl Pharmaceuticals, Inc. |
Nitroxyl Progenitors for the Treatment of Pulmonary Hypertension
|
|
AU2010328234B2
(en)
|
2009-12-07 |
2016-05-12 |
Cardioxyl Pharmaceuticals, Inc. |
N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives
|
|
CN105130855B
(zh)
*
|
2009-12-07 |
2018-05-25 |
约翰斯霍普金斯大学 |
二酰基化的羟基胺衍生物及其用途
|
|
WO2011143347A2
(en)
|
2010-05-11 |
2011-11-17 |
Sensient Colors Llc |
Film coating composition and methods of making and using the same
|
|
PL2625176T3
(pl)
|
2010-10-08 |
2017-08-31 |
Xcovery Holding Company Llc |
Podstawione związki 6-amino-pirydazyn-3-ylo-karboksyamidu jako modulatory kinazy białkowej
|
|
EP2670387A1
(de)
|
2011-02-03 |
2013-12-11 |
Lupin Limited |
Pharmazeutische orale retard-zusammensetzungen aus bepotastin
|
|
JP6177246B2
(ja)
|
2011-10-17 |
2017-08-09 |
ザ・ジョンズ・ホプキンス・ユニバーシティ |
ヒドロキシルアミンで置換された、hno供与体としてのメルドラム酸、バルビツール酸、及びピラゾロンの誘導体
|
|
BRPI1106900A2
(pt)
*
|
2011-12-26 |
2013-11-05 |
Ems Sa |
Composição farmacêutica sólida compreendendo antibótico da familia das quinolonas e processo de sua obtenção
|
|
CA3008794C
(en)
|
2012-03-29 |
2021-03-16 |
Therabiome, Llc |
Gastrointestinal site-specific oral vaccination formulations active on the ileum and appendix
|
|
EP2841058A1
(de)
*
|
2012-04-23 |
2015-03-04 |
Cadila Healthcare Limited |
Verzögert freigesetzte pharmazeutische zusammensetzungen aus salsalat
|
|
JP6306602B2
(ja)
|
2012-11-01 |
2018-04-04 |
ザ ジョンズ ホプキンス ユニバーシティ |
分子内環化−脱離による制御されたhno放出
|
|
SG10201802862WA
(en)
|
2013-01-18 |
2018-05-30 |
Cardioxyl Pharmaceuticals Inc |
Pharmaceutical compositions comprising nitroxyl donors
|
|
AU2014239883B2
(en)
|
2013-03-14 |
2019-01-17 |
Therabiome, Llc |
Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents
|
|
EP2983702A2
(de)
|
2013-04-07 |
2016-02-17 |
The Broad Institute, Inc. |
Zusammensetzungen und verfahren für personalisierte neoplasieimpfstoffe
|
|
WO2015077717A1
(en)
|
2013-11-25 |
2015-05-28 |
The Broad Institute Inc. |
Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
KR20230076867A
(ko)
|
2013-12-20 |
2023-05-31 |
더 브로드 인스티튜트, 인코퍼레이티드 |
신생항원 백신과의 병용 요법
|
|
ES2734060T3
(es)
|
2014-01-17 |
2019-12-04 |
Cardioxyl Pharmaceuticals Inc |
Donadores de nitroxilo de N-hidroximetanosulfonamida
|
|
FR3018689B1
(fr)
*
|
2014-03-20 |
2017-04-28 |
Centre Hospitalier Univ De Clermont Ferrand |
Inhibiteurs de l'acetylcholinesterase d'action centrale pour la prevention et/ou le traitement des neuropathies chimio-induites et leurs symptomes, compositions, utilisations, methodes et trousse correspondantes.
|
|
US9464061B2
(en)
|
2014-05-27 |
2016-10-11 |
The Johns Hopkins University |
N-hydroxylamino-barbituric acid derivatives
|
|
WO2015183838A1
(en)
|
2014-05-27 |
2015-12-03 |
The Johns Hopkins University |
N-hydroxylamino-barbituric acid derivatives as nitroxyl donors
|
|
EP3148972B1
(de)
|
2014-05-27 |
2019-08-21 |
Cardioxyl Pharmaceuticals, Inc. |
Pyrazolonderivate als nitroxyldonatoren
|
|
EP3234130B1
(de)
|
2014-12-19 |
2020-11-25 |
The Broad Institute, Inc. |
Verfahren zum profiling vom t-zell-rezeptor-repertoire
|
|
US10975442B2
(en)
|
2014-12-19 |
2021-04-13 |
Massachusetts Institute Of Technology |
Molecular biomarkers for cancer immunotherapy
|
|
US10202363B2
(en)
|
2014-12-23 |
2019-02-12 |
Cerecor, Inc. |
Compounds, compositions and methods
|
|
US20170042806A1
(en)
|
2015-04-29 |
2017-02-16 |
Dexcel Pharma Technologies Ltd. |
Orally disintegrating compositions
|
|
IL294183B2
(en)
|
2015-05-20 |
2023-10-01 |
Dana Farber Cancer Inst Inc |
shared neoantigens
|
|
CN107750160B
(zh)
|
2015-06-09 |
2021-06-22 |
百缮药业(苏州)有限公司 |
氟代环戊烯基胞嘧啶的用途及制备方法
|
|
WO2017040980A2
(en)
|
2015-09-04 |
2017-03-09 |
Rexahn Pharmaceuticals, Inc. |
Quinoxalinyl-piperazinamide methods of use
|
|
AU2017254477A1
(en)
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
|
US10076494B2
(en)
|
2016-06-16 |
2018-09-18 |
Dexcel Pharma Technologies Ltd. |
Stable orally disintegrating pharmaceutical compositions
|
|
MX390005B
(es)
|
2016-10-03 |
2025-03-20 |
Hangzhou Highlightll Pharmaceutical Co Ltd |
Inhibidores selectivos de jak1 novedosos y usos de los mismos.
|
|
US11549149B2
(en)
|
2017-01-24 |
2023-01-10 |
The Broad Institute, Inc. |
Compositions and methods for detecting a mutant variant of a polynucleotide
|
|
DK3488868T3
(da)
*
|
2017-11-23 |
2023-11-27 |
Medac Ges Fuer Klinische Spezialpraeparate Mbh |
Farmaceutisk sammensætning til oral indgivelse, som indeholder sulfasalazin og/eller et organisk sulfasalazinsalt, fremstillingsfremgangsmåde samt anvendelse
|
|
EP3489222A1
(de)
|
2017-11-23 |
2019-05-29 |
medac Gesellschaft für klinische Spezialpräparate mbH |
Sulfasalazinesalze, herstellungsverfahren und verwendungen
|
|
BR112020022294A2
(pt)
|
2018-05-04 |
2021-02-23 |
Tollys |
composição e uso de uma composição
|
|
WO2020072700A1
(en)
|
2018-10-02 |
2020-04-09 |
Dana-Farber Cancer Institute, Inc. |
Hla single allele lines
|
|
US20220062394A1
(en)
|
2018-12-17 |
2022-03-03 |
The Broad Institute, Inc. |
Methods for identifying neoantigens
|
|
WO2020204678A1
(ko)
*
|
2019-04-04 |
2020-10-08 |
재단법인 대구경북첨단의료산업진흥재단 |
트리메부틴 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 함유하는 암의 예방 또는 치료용 약학적 조성물
|
|
EP3955923A1
(de)
|
2019-04-18 |
2022-02-23 |
The Regents Of The University Of Michigan |
Kombination mit checkpoint-inhibitoren zur behandlung von krebs
|
|
US12394502B2
(en)
|
2019-10-02 |
2025-08-19 |
The General Hospital Corporation |
Method for predicting HLA-binding peptides using protein structural features
|
|
AR122353A1
(es)
|
2019-12-27 |
2022-09-07 |
Evelo Biosciences Inc |
Formas farmacéuticas sólidas que contienen bacterias y vesículas extracelulares microbianas
|
|
WO2021146523A1
(en)
|
2020-01-17 |
2021-07-22 |
Evelo Biosciences, Inc. |
Solid dosage forms with improved disintegration profiles
|
|
JP2023522018A
(ja)
|
2020-04-17 |
2023-05-26 |
エヴェロ バイオサイエンシズ,インコーポレーテッド |
改善された崩壊プロファイルを有する固形剤形
|
|
WO2021242793A2
(en)
|
2020-05-26 |
2021-12-02 |
The Broad Institute, Inc. |
Nucleic acid artificial mini-proteome libraries
|
|
EP4161508A1
(de)
|
2020-06-05 |
2023-04-12 |
Henry Ford Health System |
Dakalasvir zur verwendung bei der behandlung von lungen- und prostatakrebs
|
|
MX2023003089A
(es)
|
2020-09-18 |
2023-05-09 |
Evelo Biosciences Inc |
Formas farmaceuticas solidas de bacterias.
|
|
TW202227111A
(zh)
|
2020-09-21 |
2022-07-16 |
美商艾弗洛生物科技股份有限公司 |
具有改善的崩散譜之固體劑型
|
|
TW202233213A
(zh)
|
2020-10-29 |
2022-09-01 |
美商艾弗洛生物科技股份有限公司 |
包含螺旋藻組分之組成物
|
|
US20240058271A1
(en)
|
2020-12-14 |
2024-02-22 |
Kevin Huynh |
Extracellular vesicle preparations
|
|
US20240239764A1
(en)
|
2020-12-22 |
2024-07-18 |
Mekanistic Therapeutics |
Substituted aminobenzyl heteroaryl compounds as egfr and/or pi3k inhibitors
|
|
EP4267154A1
(de)
|
2020-12-22 |
2023-11-01 |
Evelo Biosciences, Inc. |
Zusammensetzungen mit tierhämoglobin
|
|
JP2024505207A
(ja)
|
2021-01-26 |
2024-02-05 |
エヴェロ バイオサイエンシズ,インコーポレーテッド |
プレボテラ(Prevotella)細胞外小胞調製物
|
|
US20240148797A1
(en)
|
2021-02-26 |
2024-05-09 |
Evelo Biosciences, Inc. |
Compositions and methods for reducing cytokine expression
|
|
WO2022187578A1
(en)
|
2021-03-05 |
2022-09-09 |
Evelo Biosciences, Inc. |
Solid dosage forms
|
|
WO2022189861A1
(en)
|
2021-03-08 |
2022-09-15 |
Tollys |
Carbohydrate conjugates of tlr3 ligands and uses thereof
|
|
TW202304415A
(zh)
|
2021-04-08 |
2023-02-01 |
美商艾弗洛生物科技股份有限公司 |
含有細菌的藥物製劑
|
|
WO2022221183A1
(en)
|
2021-04-12 |
2022-10-20 |
Evelo Biosciences, Inc. |
Fournierella extracellular vesicle preparations
|
|
WO2022251166A2
(en)
|
2021-05-25 |
2022-12-01 |
Evelo Biosciences, Inc. |
Bacterial compositions comprising soy hemoglobin
|
|
EP4385510A4
(de)
|
2021-08-10 |
2025-08-20 |
Betta Pharmaceuticals Co Ltd |
Verwendung von ensartinib oder einem salz davon bei der behandlung von krankheiten mit exon-skipping-mutation von met 14
|
|
KR20240093504A
(ko)
|
2021-09-24 |
2024-06-24 |
에벨로 바이오사이언시즈, 인크. |
박테리아 및 미생물 세포외 소포를 함유하는 고체 투여 형태
|
|
EP4426829A1
(de)
|
2021-11-01 |
2024-09-11 |
Dana-Farber Cancer Institute, Inc. |
Biologisch ausgewählte bibliotheken künstlicher miniproteome von nukleinsäuren
|
|
WO2023114293A1
(en)
|
2021-12-14 |
2023-06-22 |
Evelo Biosciences, Inc. |
Extracellular vesicle assays
|
|
WO2023114295A1
(en)
|
2021-12-14 |
2023-06-22 |
Evelo Biosciences, Inc. |
Veillonella parvula bacteria extracellular vesicle preparations
|
|
WO2023114300A1
(en)
|
2021-12-14 |
2023-06-22 |
Evelo Biosciences, Inc. |
Fournierella massiliensis bacteria extracellular vesicle preparations
|
|
WO2023146843A1
(en)
|
2022-01-25 |
2023-08-03 |
Evelo Biosciences, Inc. |
Extracellular vesicle compositions and methods of use
|
|
WO2023183396A1
(en)
|
2022-03-22 |
2023-09-28 |
Evelo Biosciences, Inc. |
Compositions and methods of treating inflammation using prevotella histicola
|
|
WO2023200837A1
(en)
|
2022-04-13 |
2023-10-19 |
Evelo Biosciences, Inc. |
Compositions and methods of treating inflammation using prevotella histicola
|
|
WO2023239728A1
(en)
|
2022-06-07 |
2023-12-14 |
Evelo Biosciences, Inc. |
Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles
|
|
WO2024102226A1
(en)
|
2022-10-14 |
2024-05-16 |
Evelo Biosciences, Inc. |
Methods for assaying drug substances and drug products by using cell lines with nf-kb- inducible reporter genes
|
|
US12531162B1
(en)
*
|
2023-05-31 |
2026-01-20 |
Northeastern University |
Multi-dimensional phenotypic space for genotype to phenotype mapping and intelligent design of cancer drug therapies using a deep learning net
|
|
WO2025043108A1
(en)
|
2023-08-23 |
2025-02-27 |
Bristol -Myers S Quibb Company |
Co-crystals of nitroxyl donating compounds
|
|
US12562256B2
(en)
*
|
2023-11-07 |
2026-02-24 |
New York University |
Systems, methods and computer-accessible medium for identifying target pairs for CAR-T therapy
|
|
WO2025101914A1
(en)
|
2023-11-10 |
2025-05-15 |
Mekanistic Therapeutics Llc |
Substituted aminobenzyl heteroaryl compounds as egfr and/or pi3k inhibitors having improved therapeutic index against solid tumors
|
|
WO2025126109A1
(en)
|
2023-12-15 |
2025-06-19 |
Ensem Therapeutics, Inc. |
Anilino-pyrazole derivatives, compositions and methods thereof
|