ATE296812T1 - 1,2-diazepanderivate als inhibitoren des interleukin-1beta umwandelnden enzyms - Google Patents

1,2-diazepanderivate als inhibitoren des interleukin-1beta umwandelnden enzyms

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Publication number
ATE296812T1
ATE296812T1 AT99909935T AT99909935T ATE296812T1 AT E296812 T1 ATE296812 T1 AT E296812T1 AT 99909935 T AT99909935 T AT 99909935T AT 99909935 T AT99909935 T AT 99909935T AT E296812 T1 ATE296812 T1 AT E296812T1
Authority
AT
Austria
Prior art keywords
compounds
gamma
interleukin
diseases
inhibitors
Prior art date
Application number
AT99909935T
Other languages
English (en)
Inventor
Marion W Wannamaker
Paul Charifson
David J Lauffer
Michael D Mullican
Original Assignee
Vertex Pharma
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Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Application granted granted Critical
Publication of ATE296812T1 publication Critical patent/ATE296812T1/de

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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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AT99909935T 1998-03-09 1999-03-09 1,2-diazepanderivate als inhibitoren des interleukin-1beta umwandelnden enzyms ATE296812T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7732798P 1998-03-09 1998-03-09
PCT/US1999/005124 WO1999046248A1 (en) 1998-03-09 1999-03-09 1,2-diazepane derivatives as interleukin-1beta converting enzyme inhibitors

Publications (1)

Publication Number Publication Date
ATE296812T1 true ATE296812T1 (de) 2005-06-15

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ID=22137418

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AT99909935T ATE296812T1 (de) 1998-03-09 1999-03-09 1,2-diazepanderivate als inhibitoren des interleukin-1beta umwandelnden enzyms

Country Status (8)

Country Link
US (1) US6426413B1 (de)
EP (1) EP1062210B1 (de)
JP (1) JP4499917B2 (de)
AT (1) ATE296812T1 (de)
AU (1) AU2901899A (de)
DE (1) DE69925581T2 (de)
ES (1) ES2244178T3 (de)
WO (1) WO1999046248A1 (de)

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EP1062210B1 (de) 2005-06-01
AU2901899A (en) 1999-09-27
JP2002506061A (ja) 2002-02-26
EP1062210A1 (de) 2000-12-27
ES2244178T3 (es) 2005-12-01
DE69925581D1 (de) 2005-07-07
HK1033828A1 (en) 2001-09-28
WO1999046248A1 (en) 1999-09-16
DE69925581T2 (de) 2006-04-27
JP4499917B2 (ja) 2010-07-14
US6426413B1 (en) 2002-07-30

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