ATE296818T1 - Substituierte 6h-dibenzo(c,h)chromene als oestrogene agentien - Google Patents
Substituierte 6h-dibenzo(c,h)chromene als oestrogene agentienInfo
- Publication number
- ATE296818T1 ATE296818T1 AT02805117T AT02805117T ATE296818T1 AT E296818 T1 ATE296818 T1 AT E296818T1 AT 02805117 T AT02805117 T AT 02805117T AT 02805117 T AT02805117 T AT 02805117T AT E296818 T1 ATE296818 T1 AT E296818T1
- Authority
- AT
- Austria
- Prior art keywords
- chromenes
- dibenzo
- substituted
- estrogenic agents
- estrogenic
- Prior art date
Links
- 150000008371 chromenes Chemical class 0.000 title 1
- 239000000262 estrogen Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34144101P | 2001-12-13 | 2001-12-13 | |
| PCT/US2002/039802 WO2003051863A1 (en) | 2001-12-13 | 2002-12-12 | SUBSTITUTED 6H-DIBENZO[c,h]CHROMENES AS ESTROGENIC AGENTS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE296818T1 true ATE296818T1 (de) | 2005-06-15 |
Family
ID=23337586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02805117T ATE296818T1 (de) | 2001-12-13 | 2002-12-12 | Substituierte 6h-dibenzo(c,h)chromene als oestrogene agentien |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6723747B2 (de) |
| EP (1) | EP1453820B1 (de) |
| JP (1) | JP2005538925A (de) |
| CN (1) | CN100429210C (de) |
| AR (1) | AR037814A1 (de) |
| AT (1) | ATE296818T1 (de) |
| AU (1) | AU2002357184A1 (de) |
| BR (1) | BR0214918A (de) |
| CA (1) | CA2470105C (de) |
| DE (1) | DE60204482T2 (de) |
| ES (1) | ES2240856T3 (de) |
| MX (1) | MXPA04005630A (de) |
| PT (1) | PT1453820E (de) |
| TW (1) | TW200301107A (de) |
| WO (1) | WO2003051863A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005014586A1 (en) | 2003-08-08 | 2005-02-17 | Arpida Ag | Novel process for the preparation of 2h-chromenes |
| US7157492B2 (en) * | 2004-02-26 | 2007-01-02 | Wyeth | Dibenzo chromene derivatives and their use as ERβ selective ligands |
| WO2006007503A1 (en) * | 2004-07-01 | 2006-01-19 | Wyeth | Tetracyclic compounds as estrogen ligands |
| CA2578164A1 (en) | 2004-09-07 | 2006-03-16 | Wyeth | 6h-[1]benzopyrano[4,3-b]quinolines and their use as estrogenic agents |
| KR20070086329A (ko) * | 2004-12-17 | 2007-08-27 | 와이어쓰 | 에스트로겐 베타 아고니스트의 신규 용도 |
| BRPI0608154A2 (pt) * | 2005-02-16 | 2016-10-11 | Wyeth Corp | métodos de tratar ou inibir mucosite, cistite por radiação em um indivíduo, e de tratar pelo menos um sintoma de exposição de um indivíduo a um agente citotóxico ou à radiação, e, composição farmacêutica |
| AR059574A1 (es) * | 2006-02-14 | 2008-04-16 | Wyeth Corp | Formulaciones farmaceuticas acuosas de ligandos selectivos er-beta |
| US9604931B2 (en) | 2007-01-22 | 2017-03-28 | Gtx, Inc. | Nuclear receptor binding agents |
| EP2106212B1 (de) | 2007-01-22 | 2014-04-02 | GTX, Inc. | Nuklearrezeptor-bindende wirkstoffe |
| US9623021B2 (en) * | 2007-01-22 | 2017-04-18 | Gtx, Inc. | Nuclear receptor binding agents |
| TW200838509A (en) * | 2007-01-31 | 2008-10-01 | Wyeth Corp | Use of ERβ selective ligands for treating acute lung injuries |
| CN108774207B (zh) * | 2018-07-30 | 2021-12-17 | 苏州大学张家港工业技术研究院 | 环戊二烯并[c]色烯化合物及其制备方法 |
| CN116332924B (zh) * | 2023-03-31 | 2025-07-25 | 西安交通大学 | (S)-2-[(6H-二苯并[b,d]吡喃-3-基)氧]丙酰胺类衍生物及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ176197A3 (cs) * | 1994-12-22 | 1998-09-16 | Ligand Pharmaceuticals Incorporated | Modulátory steroidových receptorů a způsoby jejich přípravy a použití |
| US5693647A (en) | 1994-12-22 | 1997-12-02 | Ligand Pharmaceuticals Incorporated | Steroid receptor modulator compounds and methods |
| EP1173164A2 (de) | 1999-04-16 | 2002-01-23 | AstraZeneca AB | Estrogen beta-rezeptor liganden |
-
2002
- 2002-12-10 TW TW091135700A patent/TW200301107A/zh unknown
- 2002-12-11 US US10/317,163 patent/US6723747B2/en not_active Expired - Fee Related
- 2002-12-12 JP JP2003552747A patent/JP2005538925A/ja not_active Ceased
- 2002-12-12 EP EP02805117A patent/EP1453820B1/de not_active Expired - Lifetime
- 2002-12-12 BR BRPI0214918-4A patent/BR0214918A/pt not_active IP Right Cessation
- 2002-12-12 CN CNB028248791A patent/CN100429210C/zh not_active Expired - Fee Related
- 2002-12-12 DE DE60204482T patent/DE60204482T2/de not_active Expired - Lifetime
- 2002-12-12 WO PCT/US2002/039802 patent/WO2003051863A1/en not_active Ceased
- 2002-12-12 PT PT02805117T patent/PT1453820E/pt unknown
- 2002-12-12 ES ES02805117T patent/ES2240856T3/es not_active Expired - Lifetime
- 2002-12-12 MX MXPA04005630A patent/MXPA04005630A/es active IP Right Grant
- 2002-12-12 AU AU2002357184A patent/AU2002357184A1/en not_active Abandoned
- 2002-12-12 AT AT02805117T patent/ATE296818T1/de not_active IP Right Cessation
- 2002-12-12 AR ARP020104830A patent/AR037814A1/es not_active Application Discontinuation
- 2002-12-12 CA CA2470105A patent/CA2470105C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6723747B2 (en) | 2004-04-20 |
| ES2240856T3 (es) | 2005-10-16 |
| US20030176491A1 (en) | 2003-09-18 |
| TW200301107A (en) | 2003-07-01 |
| AR037814A1 (es) | 2004-12-09 |
| EP1453820A1 (de) | 2004-09-08 |
| JP2005538925A (ja) | 2005-12-22 |
| PT1453820E (pt) | 2005-09-30 |
| CN100429210C (zh) | 2008-10-29 |
| HK1069171A1 (en) | 2005-05-13 |
| CA2470105A1 (en) | 2003-06-26 |
| CA2470105C (en) | 2010-07-27 |
| BR0214918A (pt) | 2006-05-30 |
| DE60204482D1 (de) | 2005-07-07 |
| DE60204482T2 (de) | 2005-10-27 |
| EP1453820B1 (de) | 2005-06-01 |
| WO2003051863A1 (en) | 2003-06-26 |
| CN1602307A (zh) | 2005-03-30 |
| MXPA04005630A (es) | 2004-12-06 |
| AU2002357184A1 (en) | 2003-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20042955L (no) | Substituerte fenylaftalener som estrogene midler | |
| NO20020930D0 (no) | Enkelturs, flerisolerings, brönnfraktureringssystem | |
| NO20034930D0 (no) | Substituerte cykloheksan-1,4-diaminderivater | |
| ATE447565T1 (de) | Spiro-hydantoin-verbindungen, die sich als entzündungshemmende mittel eignen | |
| FI20012372A7 (fi) | Järjestely porauksen ohjaukseen | |
| DE60213276D1 (de) | 1,2,4-thiadiazoliumverbindungen als melanocortinrezeptor-modulatoren | |
| FI20011021A0 (fi) | Järjestely porauksen ohjaukseen | |
| ATE296818T1 (de) | Substituierte 6h-dibenzo(c,h)chromene als oestrogene agentien | |
| DE60213088D1 (de) | Chromen-verbindungen | |
| AU2002366356A1 (en) | Substituted 2-phenyl benzofurans as estrogenic agents | |
| NO20033898D0 (no) | Dimeriske isoflavoner | |
| ATE323095T1 (de) | 3,7-diazabicycloc3.3.1)-formulierungen als antiarrhythmika | |
| ATE529419T1 (de) | Chromanderivate als estrogene verbindungen | |
| ATE287405T1 (de) | 5-halogen-6-phenyl-7-fluoroalkylamino- triazolopyrimidine als fungizide | |
| NO20053312D0 (no) | Benzofuranderivat. | |
| ATE320418T1 (de) | Substituierte benzo(b)azepin-2-on-verbindungen als schmerzmittel | |
| DE60214138D1 (de) | Isoxazolin-derivate als antidepressiva | |
| DE50100383D1 (de) | H-annellierte benzo [f]chromene | |
| CY1105361T1 (el) | Τετρακυκλικες ετepοενωσεις σαν ρυθμιστες υποδοχεα οιστρογονου | |
| ATE327226T1 (de) | Substituierte y-lactonverbindungen als nmda- antagonisten | |
| ATE234832T1 (de) | 1-trifluorotmethyl-4-hydroxy-7-piperidinyl- aminomethylchroman-derivate | |
| ATE332902T1 (de) | 3,7-diazabicycloc3.3.1)-formulierungen als antiarrhythmika | |
| NO20015865D0 (no) | Pyrrolidinyl-, piperidinyl- eller homopiperidinyl=substituerte (benzodioksan, benzofuran ellerbenzopyran) derivater | |
| SI1453820T1 (en) | Substituted 6h-dibenzo(c,h)chromenes as estrogenic agents | |
| UY28661A1 (es) | Derivados de cromano |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1453820 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |