ATE297240T1 - Trennungsverfahren mit längenveränderlichen chromatographischen zonen - Google Patents

Trennungsverfahren mit längenveränderlichen chromatographischen zonen

Info

Publication number
ATE297240T1
ATE297240T1 AT99950884T AT99950884T ATE297240T1 AT E297240 T1 ATE297240 T1 AT E297240T1 AT 99950884 T AT99950884 T AT 99950884T AT 99950884 T AT99950884 T AT 99950884T AT E297240 T1 ATE297240 T1 AT E297240T1
Authority
AT
Austria
Prior art keywords
draw
point
injection
column
points
Prior art date
Application number
AT99950884T
Other languages
English (en)
Inventor
Michel Bailly
Philippe Adam
Olivier Ludemann-Hombourger
Roger Marc Nicoud
Original Assignee
Inst Francais Du Petrole
Novasep
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Francais Du Petrole, Novasep filed Critical Inst Francais Du Petrole
Application granted granted Critical
Publication of ATE297240T1 publication Critical patent/ATE297240T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • B01D15/1828—Simulated moving beds characterised by process features
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99950884T 1998-10-29 1999-10-29 Trennungsverfahren mit längenveränderlichen chromatographischen zonen ATE297240T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9813600A FR2785196B1 (fr) 1998-10-29 1998-10-29 Procede et dispositif de separation avec des zones chromatographiques a longueur variable
PCT/FR1999/002653 WO2000025885A1 (fr) 1998-10-29 1999-10-29 Procede et dispositif de separation avec des zones chromatographiques a longueur variable

Publications (1)

Publication Number Publication Date
ATE297240T1 true ATE297240T1 (de) 2005-06-15

Family

ID=9532152

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99950884T ATE297240T1 (de) 1998-10-29 1999-10-29 Trennungsverfahren mit längenveränderlichen chromatographischen zonen

Country Status (8)

Country Link
US (1) US6136198A (de)
EP (1) EP1128881B1 (de)
JP (1) JP4966449B2 (de)
AT (1) ATE297240T1 (de)
CA (1) CA2348719C (de)
DE (1) DE69925749T2 (de)
FR (1) FR2785196B1 (de)
WO (1) WO2000025885A1 (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754731B1 (fr) * 1996-10-18 1999-07-02 Novasep Sa Perfectionnement aux procedes d'enrichissement d'isomeres optiques par lit mobile simule
US6413419B1 (en) * 1998-10-29 2002-07-02 Institut Francais Du Petrole Process and device for separation with variable-length chromatographic
US6375839B1 (en) * 1998-10-29 2002-04-23 Institut Francais Du Petrole Process and device for separation with variable-length chromatographic zones
WO2003026772A2 (en) * 2001-09-27 2003-04-03 Purdue Research Foundation Versatile simulated moving bed systems
US6683220B2 (en) * 2001-10-31 2004-01-27 Pfizer, Inc. Process for the preparation of optically pure or enriched racemic tetralone
DE10235385B4 (de) * 2002-08-02 2006-10-05 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren zur chromatographischen Trennung von Komponenten
US20060147924A1 (en) * 2002-09-11 2006-07-06 Ramsing Neils B Population of nucleic acids including a subpopulation of lna oligomers
US20060128955A1 (en) * 2003-05-09 2006-06-15 Vela Pharmaceuticals, Inc. Method of isolating (R)-tofisopam
FR2856313B1 (fr) * 2003-06-17 2005-07-29 Inst Francais Du Petrole Methode de gestion des vannes d'un systeme de separation a lit mobile simule
GB0325055D0 (en) * 2003-10-27 2003-12-03 Smithkline Beecham Corp New process
US20060273013A1 (en) * 2004-03-01 2006-12-07 Chin Nien-Hwa L Versatile simulated moving bed systems
DE102004025000A1 (de) 2004-05-21 2005-12-08 Bayer Technology Services Gmbh Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie
US20060086667A1 (en) * 2004-09-13 2006-04-27 Cephalon, Inc., U.S. Corporation Methods for the separation of enantiomeric sulfinylacetamides
FR2883283B1 (fr) * 2005-03-16 2007-05-18 Inst Francais Du Petrole Procede de production combinee de paraxylene et de benzene de productivite amelioree
US7211703B2 (en) * 2005-04-27 2007-05-01 Calgon Carbon Corporation Method of separating E and Z isomers of an alkene alcohol and derivatives thereof
FR2886557B1 (fr) 2005-06-02 2007-10-19 Inst Francais Du Petrole Utilisation de zeolithes de type faujasite echangee au cesium pour la desulfuration poussee de coupe essence
EP2455382B1 (de) 2005-12-13 2016-10-26 Incyte Holdings Corporation Heteroarylsubstituierte Pyrrolo[2,3-b]pyridine sowie Pyrrolo[2,3-b]pyrimidine als Januskinaseinhibitoren
FR2904776B1 (fr) * 2006-08-08 2009-01-23 Inst Francais Du Petrole Procede et dispositif de separation en lit mobile simule a nombre de vannes reduit
WO2008025887A1 (fr) * 2006-08-28 2008-03-06 Novasep Procede d'enrichissement d'un ou plusieurs composes d'un melange utilisant une phase mobile liquide contenant un gaz
FR2907021B1 (fr) * 2006-10-16 2009-02-06 Inst Francais Du Petrole Procede et dispositif de separation en lit mobile simule a nombre de vannes de grand diametre reduit
FR2907687B1 (fr) * 2006-10-30 2008-12-26 Applexion Procede de purification de sialyllactose par chromatographie
DE502007004854D1 (de) 2007-04-17 2010-10-07 Max Planck Gesellschaft Verfahren und Vorrichtung zur chromatographischen Trennung von Komponenten mit teilweiser Rückführung von Gemischfraktionen
EP3070090B1 (de) 2007-06-13 2018-12-12 Incyte Holdings Corporation Verwendung der salze des janus-kinasehemmers (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropannitril
FR2925350B1 (fr) * 2007-12-21 2009-12-11 Inst Francais Du Petrole Dispositif perfectionne de separation en lit mobile simule.
CL2009001884A1 (es) * 2008-10-02 2010-05-14 Incyte Holdings Corp Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
CA3121743A1 (en) 2009-01-15 2010-07-22 Incyte Holdings Corporation Processes for preparing jak inhibitors and related intermediate compounds
JP5775070B2 (ja) 2009-05-22 2015-09-09 インサイト・コーポレイションＩｎｃｙｔｅ Ｃｏｒｐｏｒａｔｉｏｎ ヤヌスキナーゼ阻害剤としてのピラゾール−４−イル−ピロロ［２，３−ｄ］ピリミジンおよびピロール−３−イル−ピロロ［２，３−ｄ］ピリミジンのＮ−（ヘテロ）アリール−ピロリジン誘導体
SG176111A1 (en) * 2009-05-22 2011-12-29 Incyte Corp 3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
AR078012A1 (es) 2009-09-01 2011-10-05 Incyte Corp Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
EP2519332B1 (de) 2009-12-30 2014-03-05 BASF Pharma (Callanish) Limited Chromatografisches trennverfahren mit simuliertem beweglichem bett
PT3354652T (pt) 2010-03-10 2020-07-20 Incyte Holdings Corp Derivados de piperidin-4-ilazetidina como inibidores de jak1
DE102010028916A1 (de) 2010-05-12 2011-11-17 Evonik Degussa Gmbh Verfahren zur Abtrennung von Tryptophan
RS54824B1 (sr) 2010-05-21 2016-10-31 Incyte Holdings Corp Topikalna formulacija za inhibiciju jak-a
AU2011268871C1 (en) 2010-06-25 2015-06-04 Ucb Pharma Gmbh Processes for the resolution of nitrogen substituted (S) - 5 -alkoxy- 2 -aminotetralin derivatives
WO2012068440A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
CA2818542A1 (en) 2010-11-19 2012-05-24 Incyte Corporation Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
FR2976501B1 (fr) * 2011-06-16 2013-05-31 IFP Energies Nouvelles Procede et dispositif de separation chromatographique a contre-courant simule utilisant deux adsorbeurs en parallele pour la production optimisee de paraxylene.
FR2976500B1 (fr) 2011-06-16 2013-05-31 IFP Energies Nouvelles Procede et dispositif de sepation chromatographique a contre-courant simule a faible perte de charge et nombre de zones eleve.
MY165963A (en) 2011-06-20 2018-05-18 Incyte Holdings Corp Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
FR2979252B1 (fr) * 2011-08-26 2013-08-16 IFP Energies Nouvelles Procede et dispositif de production de paraxylene en contre-courant simule a grande flexibilite
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
TW201406761A (zh) 2012-05-18 2014-02-16 Incyte Corp 做爲ｊａｋ抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
CN113384546A (zh) 2012-11-15 2021-09-14 因赛特公司 鲁索利替尼的缓释剂型
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
FR3002461B1 (fr) 2013-02-22 2016-12-09 Ifp Energies Now Procede de separation des xylenes en lit mobile simule au moyen d'un solide adsorbant zeolithique de granulometrie comprise entre 150 et 500 microns
WO2014138168A1 (en) 2013-03-06 2014-09-12 Incyte Corporation Processes and intermediates for making a jak inhibitor
CA2911273C (en) 2013-05-07 2021-04-27 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP2801604B1 (de) 2013-05-07 2017-04-12 Groupe Novasep Chromatographisches Verfahren zur Herstellung von hochreinen, mehrfach ungesättigten Fettsäuren
SG10201801069QA (en) 2013-08-07 2018-03-28 Incyte Corp Sustained release dosage forms for a jak1 inhibitor
FR3014436B1 (fr) 2013-12-11 2016-10-21 Novasep Process Procede de purification chromatographique d'un acide gras
EP3118186B1 (de) 2013-12-11 2022-02-09 Novasep Process Chromatografische anlage zur herstellung von mehrfach ungesättigten fettsäuren
FR3014435B1 (fr) 2013-12-11 2016-10-21 Novasep Process Purification d'acides gras par un procede chromatographique
BR112016015718B1 (pt) 2014-01-07 2021-12-07 Novasep Process Solutions Processo de purificação de aminoácidos aromáticos
US9498467B2 (en) 2014-05-30 2016-11-22 Incyte Corporation Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
WO2016081113A1 (en) 2014-11-20 2016-05-26 Exxonmobil Chemical Patents Inc. Xylene separation process and apparatus
WO2017155664A1 (en) 2016-03-11 2017-09-14 Exxonmobil Chemical Patents Inc. Simulated moving bed separation process
WO2017201159A1 (en) 2016-05-20 2017-11-23 Exxonmobil Chemical Patents Inc. Xylene separation process
US11154795B2 (en) 2016-10-21 2021-10-26 Novasep Equipment Solutions Use of compressed gas for moving eluent applied to chromatography
FR3063655B1 (fr) * 2017-03-13 2019-04-05 IFP Energies Nouvelles Procede de separation des xylenes en lit mobile simule et conditions operatoires optimisees
FR3064006B1 (fr) 2017-03-16 2019-03-29 Adisseo France S.A.S. Procede de fabrication de l'acide-2-hydroxy-4-methylthio-butyrique
AR113922A1 (es) 2017-12-08 2020-07-01 Incyte Corp Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
EA202091830A1 (ru) 2018-01-30 2020-12-29 Инсайт Корпорейшн Способы и промежуточные соединения для получения ингибитора jak
MD3773593T2 (ro) 2018-03-30 2024-10-31 Incyte Corp Tratament hidradenitei supurative utilizând inhibitori ai JAK
US11324718B2 (en) 2018-10-09 2022-05-10 Sartorius Chromatography Equipment Method for purifying cannabinoids
FR3105020B1 (fr) 2019-12-20 2022-09-02 Ifp Energies Now Adsorbant zéolithique pour la séparation d’isomères d’hydrocarbures
FR3105021B1 (fr) 2019-12-20 2022-08-12 Ifp Energies Now Adsorbant zéolithique pour la séparation d’isomères d’hydrocarbures
US11786859B2 (en) * 2020-02-04 2023-10-17 Tda Research, Inc. Air separation sorbent and vacuum assisted pressure swing adsorption process using the same
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms
EP4448135A1 (de) 2021-12-17 2024-10-23 Basf Se Chromatographisches trennverfahren zur effizienten reinigung mehrfach ungesättigter fettsäuren
DE102022100987A1 (de) 2022-01-17 2023-07-20 Karlsruher Institut für Technologie Funktionelles mikroventil
FR3156045B1 (fr) 2023-11-30 2025-10-31 Ifp Energies Now Procede de separation des cresols en lit mobile simule
FR3156046A1 (fr) 2023-12-01 2025-06-06 Finorga Procédé de production d’un composé chimique atropoisomère
FR3158243A1 (fr) 2024-01-17 2025-07-18 Seprosys Procédé de séparation chromatographique du lithium par lit mobile simulé

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4498991A (en) * 1984-06-18 1985-02-12 Uop Inc. Serial flow continuous separation process
FR2651148B1 (fr) * 1989-08-28 1992-05-07 Inst Francais Du Petrole Procede continu et dispositif de separation chromatographique d'un melange d'au moins trois constituants en trois effluents purifies au moyen de deux solvants.
JPH0695090B2 (ja) * 1990-09-21 1994-11-24 川崎重工業株式会社 擬似移動床式液体クロマト分離装置
JP2962589B2 (ja) * 1991-05-07 1999-10-12 オルガノ株式会社 擬似移動層式クロマト分離装置
JP3306813B2 (ja) * 1992-12-09 2002-07-24 ダイセル化学工業株式会社 擬似移動床クロマト分離法
FR2721528B1 (fr) * 1994-06-22 1996-09-06 Inst Francais Du Petrole Procédé de séparation par chromatographie en lit mobile simulé avec correction de volume mort par desynchronisation des périodes.
FR2721529B1 (fr) * 1994-06-22 1996-09-06 Inst Francais Du Petrole Procédé de séparation par chromatographie en lit mobile simulé avec correction de volume mort par diminution de longueur.
FR2754730B1 (fr) * 1996-10-18 1999-07-02 Novasep Sa Procede d'enrichissement d'isomeres optiques par lit mobile simule

Also Published As

Publication number Publication date
EP1128881B1 (de) 2005-06-08
JP2002528738A (ja) 2002-09-03
DE69925749D1 (de) 2005-07-14
JP4966449B2 (ja) 2012-07-04
DE69925749T2 (de) 2005-11-03
US6136198A (en) 2000-10-24
CA2348719C (fr) 2008-10-14
CA2348719A1 (fr) 2000-05-11
FR2785196A1 (fr) 2000-05-05
WO2000025885A1 (fr) 2000-05-11
FR2785196B1 (fr) 2000-12-15
EP1128881A1 (de) 2001-09-05

Similar Documents

Publication Publication Date Title
DE69925749D1 (de) Trennungsverfahren mit längenveränderlichen chromatographischen zonen
Kim et al. Advanced operating strategies to extend the applications of simulated moving bed chromatography
Grill Closed-loop recycling with periodic intra-profile injection: a new binary preparative chromatographic technique
CA2139033A1 (en) Method of separation into three components using a simulated moving bed
MX163038B (es) Procedimiento para separar un componente de extracto de un componente de refinado
FR2527934B1 (de)
ES540905A0 (es) Un procedimiento para separar un componente extracto de un componente refinado,contenidos en una mezcla de alimentacion
Kostanyan et al. Simultaneous concentration and separation of target compounds from multicomponent mixtures by closed-loop recycling countercurrent chromatography
BR9807377B1 (pt) processo para separação de fase lìquida de uma sacarose clorada a partir de uma mistura de reação de sacarose clorada.
DE10235385B4 (de) Verfahren zur chromatographischen Trennung von Komponenten
JPS5226624B2 (de)
MY137242A (en) Process for co-producing paraxylene and metaxylene, comprising two separation steps.
GB1479801A (en) Liquid phase chromatography analysis
CN101879381A (zh) 分离混合物组分的方法和装置
FR2370092A1 (fr) Procede et appareil pour la fabrication de pains de savon jaspe
FR2856933B1 (fr) Procede et dispositif de separation des constituants d'une charge liquide par chromatographie liquide-liquide centrifuge
Wei et al. A twin‐column recycling chromatography with solvent gradient for reinforcing the isolation of minor impurities
ATE518134T1 (de) Chromatographieverfahren
Siitonen et al. Steady state recycling chromatography with solvent removal—Effect of solvent removal constraints on process operation under ideal conditions
FI20020936A0 (fi) Kromatografinen erottelu
US2767850A (en) Thermal diffusion method
DE3472948D1 (en) Process for separating c6 olefin hydrocarbons
BR9403953A (pt) Processo de fase líquida homogênea para a produção de um carboxilato de vinila, no qual o grupo carboxilato contém pelo menos três átomos de carbono
Issaq High Performance Liquid Chromatography Separations Using Short Columns Packed with Spherical ODS Particles. II. Effect of Mobile Phase Composition on Resolution
Vakstein et al. Application of Carbonic Acids for the Descending pH Gradient Formation in the Column Filled with Hyper Cross-Linked Polysterene with Attached Carboxilic Groups

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1128881

Country of ref document: EP