ATE297440T1 - Dextran-maleinsäuremonoester und hydrogele daraus - Google Patents
Dextran-maleinsäuremonoester und hydrogele darausInfo
- Publication number
- ATE297440T1 ATE297440T1 AT99942304T AT99942304T ATE297440T1 AT E297440 T1 ATE297440 T1 AT E297440T1 AT 99942304 T AT99942304 T AT 99942304T AT 99942304 T AT99942304 T AT 99942304T AT E297440 T1 ATE297440 T1 AT E297440T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrogels
- dextran
- maleic acid
- hydrgels
- acid monoester
- Prior art date
Links
- 239000011976 maleic acid Substances 0.000 title abstract 3
- 239000000017 hydrogel Substances 0.000 abstract 5
- 229920002307 Dextran Polymers 0.000 abstract 2
- 238000006467 substitution reaction Methods 0.000 abstract 2
- 230000008961 swelling Effects 0.000 abstract 2
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- -1 alpha-D-glucopyranosyl Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 239000008137 solubility enhancer Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9857198P | 1998-08-31 | 1998-08-31 | |
| PCT/US1999/018818 WO2000012619A1 (en) | 1998-08-31 | 1999-08-25 | Dextran-maleic acid monoesters and hydrogels based thereon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE297440T1 true ATE297440T1 (de) | 2005-06-15 |
Family
ID=22269907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99942304T ATE297440T1 (de) | 1998-08-31 | 1999-08-25 | Dextran-maleinsäuremonoester und hydrogele daraus |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6476204B1 (de) |
| EP (1) | EP1147148B1 (de) |
| AT (1) | ATE297440T1 (de) |
| AU (1) | AU5571399A (de) |
| CA (1) | CA2339166C (de) |
| DE (1) | DE69925757T2 (de) |
| ES (1) | ES2241314T3 (de) |
| WO (1) | WO2000012619A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716445B2 (en) | 1999-04-12 | 2004-04-06 | Cornell Research Foundation, Inc. | Hydrogel entrapping therapeutic agent and stent with coating comprising this |
| JP4558213B2 (ja) | 1999-04-12 | 2010-10-06 | コーネル・リサーチ・ファンデーション・インコーポレイテッド | 疎水性および親水性の成分を有する水性ゲル形成システム |
| US20060177416A1 (en) | 2003-10-14 | 2006-08-10 | Medivas, Llc | Polymer particle delivery compositions and methods of use |
| US20040018228A1 (en) * | 2000-11-06 | 2004-01-29 | Afmedica, Inc. | Compositions and methods for reducing scar tissue formation |
| CA2450123C (en) | 2001-08-02 | 2013-01-29 | Cornell Research Foundation, Inc. | Biodegradable polyhydric alcohol esters |
| EP1583520A4 (de) | 2003-01-16 | 2007-05-23 | Cornell Res Foundation Inc | Teilweise biologisch abbaubares temperatur- und ph-empfindliches hydrogel |
| JP5178520B2 (ja) | 2005-09-22 | 2013-04-10 | メディバス エルエルシー | 固体ポリマー送達組成物およびその使用法 |
| CA2623198C (en) | 2005-09-22 | 2014-08-05 | Medivas, Llc | Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use |
| WO2007112046A2 (en) * | 2006-03-24 | 2007-10-04 | Medivas, Llc | Alkylene-dicarboxylate-containing biodegradable poly(ester amides) and methods of use |
| US20120114589A1 (en) * | 2008-10-22 | 2012-05-10 | Rolfes-Meyering Emily R | Swellable biodegradable polymeric matrices and methods |
| EP2373345B1 (de) * | 2008-12-17 | 2016-05-04 | The Johns Hopkins University | Biokompatible hydrogele auf polysaccharidbasis |
| CA2780490C (en) | 2009-11-10 | 2021-01-26 | The Johns Hopkins University | Hydrogel-based vascular lineage cell growth media and uses thereof |
| EP2575498A1 (de) | 2010-05-04 | 2013-04-10 | Cargill, Incorporated | Fettersatzstoffe und füllmaterialien |
| US10143776B2 (en) | 2010-06-30 | 2018-12-04 | The Johns Hopkins University | Functional vascularization with biocompatible polysaccharide-based hydrogels |
| ES2992024T3 (es) | 2011-06-23 | 2024-12-05 | Dsm Ip Assets Bv | Nuevos copolímeros de poliesteramida biodegradables para la administración de fármacos |
| US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
| WO2013153210A1 (en) | 2012-04-13 | 2013-10-17 | Nanoscape Ag | Sustained-release formulation |
| US10538864B2 (en) | 2012-10-24 | 2020-01-21 | Dsm Ip Assets, B.V. | Fibers comprising polyesteramide copolymers for drug delivery |
| US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
| WO2017124040A1 (en) * | 2016-01-17 | 2017-07-20 | Guoming Sun | Biocompatible polysaccharide hydrogels and methods of usage |
| CA3160955A1 (en) | 2019-11-12 | 2021-05-20 | Dsm Ip Assets B.V. | Polyesteramide copolymers possessing high glass transition temperatures |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4002173A (en) * | 1974-07-23 | 1977-01-11 | International Paper Company | Diester crosslinked polyglucan hydrogels and reticulated sponges thereof |
| US4032488A (en) * | 1975-10-03 | 1977-06-28 | Meito Sangyo Kabushiki Kaisha | Dextran ester-olefin compound copolymer and process for preparing same |
| GB8602115D0 (en) * | 1986-01-29 | 1986-03-05 | Courtaulds Plc | Absorbent fibres |
| US4920158A (en) * | 1989-10-11 | 1990-04-24 | Medipro Sciences Limited | Hydrogel-forming wound dressing or skin coating material |
| US5013769A (en) * | 1988-08-22 | 1991-05-07 | Medipro Sciences Limited | Method of making a hydrogel-forming wound dressing or skin coating material |
| US5527856A (en) | 1988-11-21 | 1996-06-18 | Collagen Corporation | Method of preparing crosslinked biomaterial compositions for use in tissue augmentation |
| EP0610441A4 (de) * | 1991-10-29 | 1996-01-10 | Clover Cons Ltd | Vernetzbare polysacchariden, polykationen und lipiden verwendbar zum einkapseln und abgabe von arzneimitteln. |
| US5334640A (en) | 1992-04-08 | 1994-08-02 | Clover Consolidated, Ltd. | Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods |
| US5393798A (en) | 1992-06-05 | 1995-02-28 | Spenco Medical Corporation | Hydrogel material and method of preparation |
| US5541304A (en) | 1994-05-02 | 1996-07-30 | Hercules Incorporated | Crosslinked hydrogel compositions with improved mechanical performance |
| US5658592A (en) | 1994-05-13 | 1997-08-19 | Kuraray Co., Ltd. | Medical crosslinked polymer gel of carboxylic polysaccharide and diaminoalkane |
| DE4426008A1 (de) | 1994-07-22 | 1996-01-25 | Cassella Ag | Hydrophile, hochquellfähige Hydrogele |
| DE19529409A1 (de) | 1995-08-10 | 1997-02-13 | Wolff Walsrode Ag | Maleinsäureadditionsproduktgruppen enthaltende, thermoplastische und biologisch abbaubare Polysaccharidester/-etherester |
-
1999
- 1999-08-25 AT AT99942304T patent/ATE297440T1/de not_active IP Right Cessation
- 1999-08-25 CA CA002339166A patent/CA2339166C/en not_active Expired - Fee Related
- 1999-08-25 ES ES99942304T patent/ES2241314T3/es not_active Expired - Lifetime
- 1999-08-25 US US09/743,790 patent/US6476204B1/en not_active Expired - Lifetime
- 1999-08-25 WO PCT/US1999/018818 patent/WO2000012619A1/en not_active Ceased
- 1999-08-25 AU AU55713/99A patent/AU5571399A/en not_active Abandoned
- 1999-08-25 DE DE69925757T patent/DE69925757T2/de not_active Expired - Lifetime
- 1999-08-25 EP EP99942304A patent/EP1147148B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69925757T2 (de) | 2006-03-23 |
| CA2339166A1 (en) | 2000-03-09 |
| CA2339166C (en) | 2008-01-15 |
| WO2000012619A1 (en) | 2000-03-09 |
| EP1147148A1 (de) | 2001-10-24 |
| EP1147148B1 (de) | 2005-06-08 |
| EP1147148A4 (de) | 2004-04-07 |
| US6476204B1 (en) | 2002-11-05 |
| DE69925757D1 (de) | 2005-07-14 |
| AU5571399A (en) | 2000-03-21 |
| ES2241314T3 (es) | 2005-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |