ATE297954T1 - Polymere mit uniformem molekulargewicht - Google Patents
Polymere mit uniformem molekulargewichtInfo
- Publication number
- ATE297954T1 ATE297954T1 AT00958841T AT00958841T ATE297954T1 AT E297954 T1 ATE297954 T1 AT E297954T1 AT 00958841 T AT00958841 T AT 00958841T AT 00958841 T AT00958841 T AT 00958841T AT E297954 T1 ATE297954 T1 AT E297954T1
- Authority
- AT
- Austria
- Prior art keywords
- polymer
- molecular weight
- less
- alkyl
- weight polymers
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 125000006702 (C1-C18) alkyl group Chemical group 0.000 abstract 2
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000000580 polymer-drug conjugate Substances 0.000 abstract 1
- 238000010526 radical polymerization reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/10—Esters
- C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
- C08F20/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F20/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
- C08F20/02—Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
- C08F20/10—Esters
- C08F20/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F246/00—Copolymers in which the nature of only the monomers in minority is defined
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99307152 | 1999-09-08 | ||
| PCT/GB2000/003456 WO2001018080A1 (en) | 1999-09-08 | 2000-09-08 | Uniform molecular weight polymers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE297954T1 true ATE297954T1 (de) | 2005-07-15 |
Family
ID=8241613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00958841T ATE297954T1 (de) | 1999-09-08 | 2000-09-08 | Polymere mit uniformem molekulargewicht |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6803438B1 (de) |
| EP (1) | EP1222217B1 (de) |
| JP (1) | JP4883515B2 (de) |
| AT (1) | ATE297954T1 (de) |
| AU (1) | AU7025600A (de) |
| DE (1) | DE60020864T2 (de) |
| WO (1) | WO2001018080A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001288829A1 (en) | 2000-09-06 | 2002-03-22 | Ap Pharma, Inc. | Degradable polyacetal polymers |
| JP4693015B2 (ja) * | 2001-03-14 | 2011-06-01 | 日本化学工業株式会社 | フルオロアルキル基含有オリゴマー類、その製造方法、界面活性剤、抗菌剤及び樹脂組成物 |
| GB0131112D0 (en) * | 2001-12-31 | 2002-02-13 | Univ London Pharmacy | Block copolymers |
| WO2003062290A1 (en) | 2002-01-16 | 2003-07-31 | Biocompatibles Uk Limited | Polymer conjugates |
| ES2283849T3 (es) * | 2002-08-09 | 2007-11-01 | Ottawa Health Research Institute | Matriz biosintetica y utilizaciones de la misma. |
| AU2003267603A1 (en) | 2002-09-27 | 2004-04-19 | Octel America, Inc | Fuel additive composition |
| DE10256558A1 (de) * | 2002-12-04 | 2004-09-16 | Supramol Parenteral Colloids Gmbh | Ester von Polysaccharid Aldonsäuren, Verfahren zu ihrer Herstellung und Verwendung zur Kopplung an pharmazeutische Wirkstoffe |
| GB0301014D0 (en) * | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
| GB0316294D0 (en) | 2003-07-11 | 2003-08-13 | Polytherics Ltd | Conjugated biological molecules and their preparation |
| GB0400264D0 (en) * | 2004-01-07 | 2004-02-11 | Polytherics Ltd | Complexes |
| US20070142287A1 (en) * | 2005-12-20 | 2007-06-21 | Biomed Solutions, Llc | Compositions And Methods For Treatment Of Cancer |
| EP1849600B1 (de) * | 2006-04-25 | 2013-12-11 | Eastman Kodak Company | Einbrennbare strahlungsempfindliche Elemente mit hoher Chemikalienresistenz |
| JP5340956B2 (ja) * | 2006-12-20 | 2013-11-13 | アーケマ・インコーポレイテッド | ポリマーの封入および/または結合 |
| MX344076B (es) | 2008-06-30 | 2016-12-05 | Esbatech Alcon Biomed Res Unit | Polipeptidos funcionalizados. |
| US8697074B2 (en) | 2008-07-10 | 2014-04-15 | Esbatech, An Alcon Biomedical Research Unit Llc | Methods and compositions for enhanced delivery of macromolecules |
| ES2536882T3 (es) | 2008-07-21 | 2015-05-29 | Polytherics Limited | Nuevos reactivos y procedimiento de conjugación de moléculas biológicas |
| WO2011075185A1 (en) | 2009-12-18 | 2011-06-23 | Oligasis | Targeted drug phosphorylcholine polymer conjugates |
| US9895449B2 (en) | 2010-05-25 | 2018-02-20 | Syndevrx, Inc. | Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof |
| ES2853204T3 (es) | 2010-05-25 | 2021-09-15 | Syndevrx Inc | Inhibidores de MetAP2 conjugado con polímero, y métodos terapéuticos de uso de los mismos |
| EP2747753B1 (de) * | 2011-08-22 | 2023-03-29 | Carnegie Mellon University | Radikalische atomtransfer-polymerisation unter biologisch verträglichen bedingungen |
| EP2822598A4 (de) | 2012-03-05 | 2016-04-13 | Univ Ramot | Polymere mit daran konjugierten therapeutischen wirkstoffen, verfahren zur herstellung davon und verwendungen davon |
| KR102048110B1 (ko) | 2012-07-11 | 2019-11-22 | 코베스트로 도이칠란드 아게 | 이소시아네이트 제조에서 증류 잔류물의 후처리 방법 |
| AU2014250983B2 (en) | 2013-04-10 | 2019-04-11 | Syndevrx, Inc. | MetAP2 inhibitors and methods of treating obesity |
| WO2015035342A2 (en) | 2013-09-08 | 2015-03-12 | Oligasis Llc | Factor viii zwitterionic polymer conjugates |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| JP6849590B2 (ja) | 2014-10-17 | 2021-03-24 | コディアック サイエンシーズ インコーポレイテッドKodiak Sciences Inc. | ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート |
| US10618991B2 (en) * | 2015-09-23 | 2020-04-14 | Northwestern University | Reprocessable cross-linked network polymers with alkoxyamine dynamic covalent bonds |
| US9969722B2 (en) | 2015-12-10 | 2018-05-15 | Syndevrx, Inc. | Fumagillol derivatives and polymorphs thereof |
| BR112018013407A2 (en) | 2015-12-30 | 2018-12-18 | Kodiak Sciences Inc. | antibodies and conjugates thereof |
| EP3402529A1 (de) | 2016-01-11 | 2018-11-21 | Syndevrx, Inc. | Behandlung von durch stoffwechselstörungen hervorgerufen tumoren |
| SG11202008242XA (en) | 2018-03-02 | 2020-09-29 | Kodiak Sciences Inc | Il-6 antibodies and fusion constructs and conjugates thereof |
| CA3117666A1 (en) | 2018-10-26 | 2020-04-30 | Syndevrx, Inc. | Biomarkers of metap2 inhibitors and applications thereof |
| US11912784B2 (en) | 2019-10-10 | 2024-02-27 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1044797B (it) * | 1974-10-15 | 1980-04-21 | Ferruti Paolo | Alti polimeri contenenti radicali prostaglandinici processo per la loro preparazione e loro impiego |
| DE2631656C2 (de) * | 1976-07-14 | 1983-02-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung eines Hydroxysuccinimidoester-Derivats zur Bindung von biologisch aktiven Proteinen aneinander und/oder an flüssige oder feste Trägerstoffe |
| US5200462A (en) * | 1991-01-25 | 1993-04-06 | Eastman Kodak Company | Succinimide containing polymers and lattices prepared from same |
| JPH04261415A (ja) * | 1991-02-14 | 1992-09-17 | Nitto Kasei Co Ltd | 加水分解性の樹脂組成物及び海中防汚塗料 |
| JPH05113551A (ja) * | 1991-10-23 | 1993-05-07 | Seiko Epson Corp | ソフトコンタクトレンズ |
| EP0951485B1 (de) * | 1997-01-10 | 2003-04-02 | E.I. Du Pont De Nemours And Company | Verfahren zur kontrolle des molekulargewichts und der struktur eines polymers |
| EP1686143A3 (de) * | 1998-06-19 | 2006-08-16 | Kaneka Corporation | Verfahren zur Herstellung von vernetzen Polymeren und vernetzte Polymere |
-
2000
- 2000-09-08 EP EP00958841A patent/EP1222217B1/de not_active Expired - Lifetime
- 2000-09-08 WO PCT/GB2000/003456 patent/WO2001018080A1/en not_active Ceased
- 2000-09-08 US US10/070,318 patent/US6803438B1/en not_active Expired - Lifetime
- 2000-09-08 AT AT00958841T patent/ATE297954T1/de not_active IP Right Cessation
- 2000-09-08 JP JP2001522301A patent/JP4883515B2/ja not_active Expired - Fee Related
- 2000-09-08 AU AU70256/00A patent/AU7025600A/en not_active Abandoned
- 2000-09-08 DE DE60020864T patent/DE60020864T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6803438B1 (en) | 2004-10-12 |
| EP1222217A1 (de) | 2002-07-17 |
| DE60020864T2 (de) | 2006-04-27 |
| WO2001018080A1 (en) | 2001-03-15 |
| EP1222217B1 (de) | 2005-06-15 |
| JP4883515B2 (ja) | 2012-02-22 |
| JP2003508606A (ja) | 2003-03-04 |
| AU7025600A (en) | 2001-04-10 |
| DE60020864D1 (de) | 2005-07-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |