ATE298328T1 - Taxan-derivate für die behandlung von krebs - Google Patents

Taxan-derivate für die behandlung von krebs

Info

Publication number: ATE298328T1
Authority: AT; Austria
Prior art keywords: cancer; treatment; taxan derivatives; derivatives; taxan
Prior art date: 2000-03-17

Application number

AT01918514T

Other languages

English (en)

Inventor

John F Kadow

Wendy S Schwartz

Paul M Scola

Qiufen May Xue

Mark D Wittman

Mu-Jen Wu

Original Assignee

Bristol Myers Squibb Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-17

Filing date

2001-03-09

Publication date

2005-07-15

2001-03-09 Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co

2005-07-15 Application granted granted Critical

2005-07-15 Publication of ATE298328T1 publication Critical patent/ATE298328T1/de

Links

206010028980 Neoplasm Diseases 0.000 title 1
201000011510 cancer Diseases 0.000 title 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT01918514T 2000-03-17 2001-03-09 Taxan-derivate für die behandlung von krebs ATE298328T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US19017400P	2000-03-17	2000-03-17
PCT/US2001/007666 WO2001070718A1 (en)	2000-03-17	2001-03-09	Taxane anticancer agents

Publications (1)

Publication Number	Publication Date
ATE298328T1 true ATE298328T1 (de)	2005-07-15

Family

ID=22700293

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01918514T ATE298328T1 (de)	2000-03-17	2001-03-09	Taxan-derivate für die behandlung von krebs

Country Status (9)

Country	Link
US (1)	US6362217B2 (de)
EP (1)	EP1263749B1 (de)
JP (1)	JP2003528091A (de)
AT (1)	ATE298328T1 (de)
AU (2)	AU4558201A (de)
CA (1)	CA2400645A1 (de)
DE (1)	DE60111614T2 (de)
ES (1)	ES2242741T3 (de)
WO (1)	WO2001070718A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6916942B2 (en) *	2000-02-03	2005-07-12	Bristol-Myers Squibb Company	Process for the preparation of C-4 carbonate taxanes
UY27185A1 (es) *	2001-02-28	2002-09-30	Bristol Myers Squibb Co	Dosificación metronómica de taxanos
WO2003097598A1 (en) *	2002-05-16	2003-11-27	Shionogi & Co., Ltd.	Compound exhibiting pgd 2 receptor antagonism
JP4954983B2 (ja)	2005-05-18	2012-06-20	ファーマサイエンス・インコーポレイテッド	Ｂｉｒドメイン結合化合物
SG10201407457UA (en)	2006-05-16	2014-12-30	Pharmascience Inc	Iap bir domain binding compounds
CN101735179B (zh) *	2008-11-19	2012-09-12	上海百灵医药科技有限公司	一种多烯紫杉醇的制备方法，其中间体及制备方法
MX340870B (es)	2010-02-12	2016-07-27	Pharmascience Inc	Compuestos de unión del dominio de repetición de inhibidores de proteínas de apoptosis de baculovirus.

Family Cites Families (28)

* Cited by examiner, † Cited by third party
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FR2601675B1 (fr)	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US4960790A (en)	1989-03-09	1990-10-02	University Of Kansas	Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof
MY110249A (en)	1989-05-31	1998-03-31	Univ Florida State	Method for preparation of taxol using beta lactam
KR960000442B1 (ko)	1990-11-26	1996-01-06	미쓰비시덴키 가부시키가이샤	이온전류 검출장치
US5283253A (en)	1991-09-23	1994-02-01	Florida State University	Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5990325A (en) *	1993-03-05	1999-11-23	Florida State University	Process for the preparation of 9-desoxotaxol, 9-desoxobaccatin III and analogs thereof
US5478854A (en)	1992-10-01	1995-12-26	Bristol-Myers Squibb Company	Deoxy taxols
FR2697752B1 (fr) *	1992-11-10	1995-04-14	Rhone Poulenc Rorer Sa	Compositions antitumorales contenant des dérivés du taxane.
IL108443A0 (en)	1993-01-29	1994-04-12	Univ Florida State	C7 taxane derivatives and pharmaceutical compositions containing them
US6187916B1 (en) *	1993-02-01	2001-02-13	Research Foundation Of State University Of New York	Process for the preparation of taxane derivatives and β-lactam intermediates therefor
US6232477B1 (en) *	1996-03-25	2001-05-15	Aventis Pharma S.A.	Methods of preparing new taxoids and pharmaceutical compositions containing them
JP3031715B2 (ja) *	1993-02-05	2000-04-10	ブリンモーアーカレッジ	様々なａ環側鎖を有するタキソール、類似体及び中間体の合成
EP0982302B1 (de)	1993-06-11	2004-04-14	PHARMACIA & UPJOHN COMPANY	Delta 6,7-Taxol Derivate antineoplastische Verwendung und diese enthaltende pharmazeutische Zusammenstellungen
FR2712289B1 (fr) *	1993-11-08	1996-01-05	Rhone Poulenc Rorer Sa	Nouveaux dérivés de taxicine, leur préparation et les compositions pharmaceutiques qui les contiennent.
ES2179868T3 (es) *	1994-01-11	2003-02-01	Scripps Research Inst	Nanoestructuras de taxo-diterpenoide autoensambladas.
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives
US6248572B1 (en) *	1995-04-27	2001-06-19	Samyang, Genex, Corporation	Production of taxol from taxus plant cell culture adding silver nitrate
KR100380875B1 (ko) *	1995-04-28	2003-10-10	다이이찌 세이야꾸 가부시기가이샤	펜타사이클릭화합물
US6245805B1 (en)	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US5977163A (en) *	1996-03-12	1999-11-02	Pg-Txl Company, L. P.	Water soluble paclitaxel prodrugs
US5773461A (en)	1996-06-06	1998-06-30	Bristol-Myers Squibb Company	7-deoxy-6-substituted paclitaxels
CA2188190A1 (en) *	1996-10-18	1998-04-18	Sarala Balachandran	The semi-synthesis of a protected bacatin iii compound
US5977386A (en)	1996-12-24	1999-11-02	Bristol-Myers Squibb Company	6-thio-substituted paclitaxels
US5912264A (en)	1997-03-03	1999-06-15	Bristol-Myers Squibb Company	6-halo-or nitrate-substituted paclitaxels
US7288665B1 (en) *	1997-08-18	2007-10-30	Florida State University	Process for selective derivatization of taxanes
KR100551945B1 (ko) *	1997-12-19	2006-02-20	가부시키가이샤 야쿠루트 혼샤	택산 유도체
US6229207B1 (en) *	2000-01-13	2001-05-08	Advanced Micro Devices, Inc.	Organic pin grid array flip chip carrier package
US6281368B1 (en) *	2000-03-16	2001-08-28	Napro Biotherapeutics, Inc.	Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III

2001
- 2001-03-08 US US09/802,264 patent/US6362217B2/en not_active Expired - Lifetime
- 2001-03-09 DE DE60111614T patent/DE60111614T2/de not_active Expired - Fee Related
- 2001-03-09 AU AU4558201A patent/AU4558201A/xx active Pending
- 2001-03-09 CA CA002400645A patent/CA2400645A1/en not_active Abandoned
- 2001-03-09 EP EP01918514A patent/EP1263749B1/de not_active Expired - Lifetime
- 2001-03-09 AT AT01918514T patent/ATE298328T1/de not_active IP Right Cessation
- 2001-03-09 WO PCT/US2001/007666 patent/WO2001070718A1/en not_active Ceased
- 2001-03-09 ES ES01918514T patent/ES2242741T3/es not_active Expired - Lifetime
- 2001-03-09 JP JP2001568922A patent/JP2003528091A/ja active Pending
- 2001-03-09 AU AU2001245582A patent/AU2001245582B2/en not_active Ceased

Also Published As

Publication number	Publication date
CA2400645A1 (en)	2001-09-27
US20020016356A1 (en)	2002-02-07
EP1263749A1 (de)	2002-12-11
ES2242741T3 (es)	2005-11-16
AU4558201A (en)	2001-10-03
EP1263749B1 (de)	2005-06-22
AU2001245582B2 (en)	2005-07-28
EP1263749A4 (de)	2003-06-18
DE60111614T2 (de)	2006-05-11
WO2001070718A1 (en)	2001-09-27
US6362217B2 (en)	2002-03-26
JP2003528091A (ja)	2003-09-24
DE60111614D1 (de)	2005-07-28

Legal Events

Date

Code

Title

Description

2006-03-15

UEP

Publication of translation of european patent specification

Ref document number: 1263749

Country of ref document: EP

2007-12-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0960107T3 (da)	2003-02-10	6-Thiosubstituerede paclitaxeler
SE0301700D0 (sv)	2003-06-10	Novel compounds
IS6658A (is)	2002-12-17	Ný efnasambönd
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SE0202539D0 (sv)	2002-08-27	Compounds
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DE60021381D1 (de)	2005-08-25	Chinonverbindungen zur behandlung von krankheiten
SE0302139D0 (sv)	2003-07-28	Novel compounds
ATE405568T1 (de)	2008-09-15	Cytotoxische mittel
NO20043016L (no)	2004-07-15	6-aminomorfinan-derivater, fremgangsmate for fremstilling og anvendelse derav
MX9601994A (es)	1997-08-30	Profarmacos de derivados de paclitaxel.
SE0102716D0 (sv)	2001-08-14	Novel compounds
DE602004021363D1 (de)	2009-07-16	Imidazotriazin verbindungen zur behandlung von krebserkrankungen
DE60111614D1 (de)	2005-07-28	Taxan-derivate für die behandlung von krebs
TR200402030T4 (tr)	2004-09-21	İkame edilen I-aminobutan-3-ol-türevleri
SE0300457D0 (sv)	2003-02-19	Novel compounds