ATE298349T1 - Verfahren zur depolymerisierung von glykosaminoglykanen und so hergestellte produkte - Google Patents

Verfahren zur depolymerisierung von glykosaminoglykanen und so hergestellte produkte

Info

Publication number
ATE298349T1
ATE298349T1 AT03711967T AT03711967T ATE298349T1 AT E298349 T1 ATE298349 T1 AT E298349T1 AT 03711967 T AT03711967 T AT 03711967T AT 03711967 T AT03711967 T AT 03711967T AT E298349 T1 ATE298349 T1 AT E298349T1
Authority
AT
Austria
Prior art keywords
depolymerizing
glycosaminoglycans
products produced
heparin
relates
Prior art date
Application number
AT03711967T
Other languages
English (en)
Inventor
Sergio Gonella
Ambrosi Luigi De
Elena Vismara
Original Assignee
Derivati Organici Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Derivati Organici Lab filed Critical Derivati Organici Lab
Application granted granted Critical
Publication of ATE298349T1 publication Critical patent/ATE298349T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT03711967T 2002-03-12 2003-03-11 Verfahren zur depolymerisierung von glykosaminoglykanen und so hergestellte produkte ATE298349T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02425142A EP1344781A1 (de) 2002-03-12 2002-03-12 Verfahren zur Depolymerisierung von Glykosaminoglykanen und so hergestellte Produkte
PCT/EP2003/002462 WO2003076474A1 (en) 2002-03-12 2003-03-11 Process for the physical depolymerization of glycosaminoglycanes and products obtained therefrom

Publications (1)

Publication Number Publication Date
ATE298349T1 true ATE298349T1 (de) 2005-07-15

Family

ID=27763488

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03711967T ATE298349T1 (de) 2002-03-12 2003-03-11 Verfahren zur depolymerisierung von glykosaminoglykanen und so hergestellte produkte

Country Status (12)

Country Link
US (1) US7091337B2 (de)
EP (2) EP1344781A1 (de)
JP (1) JP4440650B2 (de)
AT (1) ATE298349T1 (de)
AU (1) AU2003218725A1 (de)
CA (1) CA2446695C (de)
DE (1) DE60300877T2 (de)
DK (1) DK1404720T3 (de)
ES (1) ES2244929T3 (de)
PT (1) PT1404720E (de)
SI (1) SI1404720T1 (de)
WO (1) WO2003076474A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1475391A1 (de) * 2003-05-09 2004-11-10 Laboratori Derivati Organici S.P.A. Verfahren zur physikalischen Depolymerisation von Glykosaminoglykanen und dadurch erhaltene Produkte
EP1524276A1 (de) * 2003-10-16 2005-04-20 Laboratori Derivati Organici S.P.A. Mehrstufenverfahren für die physikalisische Depolymerisation von Heparin und die so erhaltenen Produkte
US7939512B2 (en) * 2004-10-13 2011-05-10 Laboratori Derivati Organici Spa Multistep process for the physical depolymerization of heparin and products obtained therefrom
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
EP2109626A1 (de) * 2007-01-22 2009-10-21 Akzo Nobel N.V. Verfahren zur herstellung von celluloseether

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213384B (it) * 1986-11-24 1989-12-20 Lab Derivati Organici Mediolan Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare.
IT1230582B (it) * 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
JP2000237294A (ja) * 1999-02-18 2000-09-05 Denki Kagaku Kogyo Kk ヒアルロン酸ゲルを含有する医用材料
IT1312107B1 (it) * 1999-05-14 2002-04-04 Umberto Cornelli Glicosaminoglicani aventi peso molecolare medio di 2400 d atti altrattamento della demenza senile
US6383344B1 (en) * 2000-07-19 2002-05-07 Genzyme Corporation Molecular weight reduction of polymer using irradiation treatment

Also Published As

Publication number Publication date
DK1404720T3 (da) 2005-10-24
ES2244929T3 (es) 2005-12-16
SI1404720T1 (sl) 2005-12-31
AU2003218725A1 (en) 2003-09-22
CA2446695A1 (en) 2003-09-18
US20040186279A1 (en) 2004-09-23
DE60300877D1 (de) 2005-07-28
JP4440650B2 (ja) 2010-03-24
DE60300877T2 (de) 2006-07-27
JP2005520005A (ja) 2005-07-07
US7091337B2 (en) 2006-08-15
EP1404720B1 (de) 2005-06-22
EP1344781A1 (de) 2003-09-17
CA2446695C (en) 2008-10-07
EP1404720A1 (de) 2004-04-07
PT1404720E (pt) 2005-11-30
WO2003076474A1 (en) 2003-09-18

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