ATE287882T1 - Verfahren zur herstellung von imidazolverbindungen - Google Patents
Verfahren zur herstellung von imidazolverbindungenInfo
- Publication number
- ATE287882T1 ATE287882T1 AT02722184T AT02722184T ATE287882T1 AT E287882 T1 ATE287882 T1 AT E287882T1 AT 02722184 T AT02722184 T AT 02722184T AT 02722184 T AT02722184 T AT 02722184T AT E287882 T1 ATE287882 T1 AT E287882T1
- Authority
- AT
- Austria
- Prior art keywords
- imidazole compounds
- producing imidazole
- producing
- compounds
- imidazole
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N 1H-imidazole Chemical class C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Resins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01200928 | 2001-03-12 | ||
| PCT/EP2002/002459 WO2002072574A1 (en) | 2001-03-12 | 2002-03-05 | Process for the preparation of imidazole compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE287882T1 true ATE287882T1 (de) | 2005-02-15 |
Family
ID=8180004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02722184T ATE287882T1 (de) | 2001-03-12 | 2002-03-05 | Verfahren zur herstellung von imidazolverbindungen |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6844439B2 (de) |
| EP (1) | EP1373255B1 (de) |
| JP (1) | JP4257698B2 (de) |
| KR (1) | KR100849042B1 (de) |
| CN (1) | CN1246318C (de) |
| AR (1) | AR035944A1 (de) |
| AT (1) | ATE287882T1 (de) |
| AU (1) | AU2002253101B2 (de) |
| BR (1) | BRPI0208075B8 (de) |
| CA (1) | CA2438421C (de) |
| CZ (1) | CZ300622B6 (de) |
| DE (1) | DE60202755T2 (de) |
| DK (1) | DK1373255T3 (de) |
| EA (1) | EA006770B1 (de) |
| EE (1) | EE05247B1 (de) |
| ES (1) | ES2236505T3 (de) |
| HR (1) | HRP20030695B1 (de) |
| HU (1) | HU230282B1 (de) |
| IL (2) | IL157839A0 (de) |
| MX (1) | MXPA03008205A (de) |
| MY (1) | MY124838A (de) |
| NO (1) | NO324954B1 (de) |
| NZ (1) | NZ528620A (de) |
| PL (1) | PL208238B1 (de) |
| PT (1) | PT1373255E (de) |
| SI (1) | SI1373255T1 (de) |
| SK (1) | SK287807B6 (de) |
| TW (1) | TWI249532B (de) |
| UA (1) | UA74871C2 (de) |
| WO (1) | WO2002072574A1 (de) |
| ZA (1) | ZA200307117B (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60221804T2 (de) | 2001-03-12 | 2008-05-15 | Avanir Pharmaceuticals, San Diego | Benzimidazolderivate zur ige-modulierung und zellproliferationshemmung |
| WO2004024655A2 (en) | 2002-09-12 | 2004-03-25 | Avanir Pharmaceuticals | Phenyl-indole compounds for modulating ige and inhibiting cellular proliferation |
| TWI276631B (en) | 2002-09-12 | 2007-03-21 | Avanir Pharmaceuticals | Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation |
| WO2005089504A2 (en) * | 2004-03-18 | 2005-09-29 | The Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| ATE471316T1 (de) * | 2004-05-03 | 2010-07-15 | Janssen Pharmaceutica Nv | Diastereoselektives syntheseverfahren mit 6-brom- 4-(3-chlorphenyl)-2-methoxychinolin |
| WO2005105782A1 (en) | 2004-05-03 | 2005-11-10 | Janssen Pharmaceutica N.V. | Diastereoselective addition of lithiated n-methylimidazole on sulfinimines |
| WO2005105784A1 (en) * | 2004-05-03 | 2005-11-10 | Janssen Pharmaceutica N.V. | Diastereoselective synthesis process for the preparation of imidazole compounds |
| US20070213366A1 (en) | 2005-12-23 | 2007-09-13 | Justman Craig J | Treatment of Synucleinopathies |
| US8232402B2 (en) * | 2008-03-12 | 2012-07-31 | Link Medicine Corporation | Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications |
| KR101044430B1 (ko) * | 2009-09-25 | 2011-06-27 | 듀오백코리아 주식회사 | 요추받이를 포함하는 의자의 등 지지 장치 |
| KR101107900B1 (ko) * | 2009-10-21 | 2012-01-25 | 성용기업 주식회사 | 의자용 허리지지장치 |
| JP6630742B2 (ja) | 2015-08-17 | 2020-01-15 | クラ オンコロジー， インコーポレイテッド | ファルネシルトランスフェラーゼ阻害剤を用いて癌患者を治療する方法 |
| EP3534885B1 (de) | 2016-11-03 | 2021-01-20 | Kura Oncology, Inc. | Farnesyltransferase-inhibitoren zur verwendung bei der behandlung von krebs |
| CN110234639A (zh) * | 2016-12-08 | 2019-09-13 | 杭州领业医药科技有限公司 | 替吡法尼的晶型及其制备方法及药物组合物 |
| CN112424149B (zh) | 2018-05-18 | 2023-06-23 | 库拉肿瘤学公司 | 替吡法尼的合成 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW349948B (en) | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| SK283335B6 (sk) * | 1995-12-08 | 2003-06-03 | Janssen Pharmaceutica N. V. | (Imidazol-5-yl)metyl-2-chinolinónové deriváty, spôsob a medziprodukty na ich prípravu, ich použitie a farmaceutické kompozície na ich báze |
| TW591030B (en) | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| EP0977750B1 (de) | 1997-04-25 | 2007-07-04 | Janssen Pharmaceutica N.V. | Chinazolinone die farnesyltransferase hemmen |
| AP2001002079A0 (en) * | 1998-08-27 | 2001-03-31 | Pfizer Prod Inc | Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents. |
| CA2341739C (en) | 1998-08-27 | 2005-07-12 | Pfizer Products Inc. | Quinolin-2-one derivatives useful as anticancer agents |
-
2002
- 2002-03-05 SK SK1246-2003A patent/SK287807B6/sk unknown
- 2002-03-05 KR KR1020037010091A patent/KR100849042B1/ko not_active Expired - Lifetime
- 2002-03-05 SI SI200230100T patent/SI1373255T1/xx unknown
- 2002-03-05 IL IL15783902A patent/IL157839A0/xx unknown
- 2002-03-05 BR BR0208075-3 patent/BRPI0208075B8/pt not_active IP Right Cessation
- 2002-03-05 PL PL363263A patent/PL208238B1/pl unknown
- 2002-03-05 CA CA2438421A patent/CA2438421C/en not_active Expired - Lifetime
- 2002-03-05 EP EP02722184A patent/EP1373255B1/de not_active Expired - Lifetime
- 2002-03-05 EA EA200300998A patent/EA006770B1/ru not_active IP Right Cessation
- 2002-03-05 US US10/471,215 patent/US6844439B2/en not_active Expired - Lifetime
- 2002-03-05 AU AU2002253101A patent/AU2002253101B2/en not_active Expired
- 2002-03-05 AT AT02722184T patent/ATE287882T1/de active
- 2002-03-05 CZ CZ20032704A patent/CZ300622B6/cs not_active IP Right Cessation
- 2002-03-05 CN CNB02806335XA patent/CN1246318C/zh not_active Expired - Lifetime
- 2002-03-05 MX MXPA03008205A patent/MXPA03008205A/es active IP Right Grant
- 2002-03-05 HR HR20030695A patent/HRP20030695B1/xx not_active IP Right Cessation
- 2002-03-05 EE EEP200300442A patent/EE05247B1/xx unknown
- 2002-03-05 PT PT02722184T patent/PT1373255E/pt unknown
- 2002-03-05 WO PCT/EP2002/002459 patent/WO2002072574A1/en not_active Ceased
- 2002-03-05 HU HU0303443A patent/HU230282B1/hu unknown
- 2002-03-05 JP JP2002571490A patent/JP4257698B2/ja not_active Expired - Lifetime
- 2002-03-05 DE DE60202755T patent/DE60202755T2/de not_active Expired - Lifetime
- 2002-03-05 NZ NZ528620A patent/NZ528620A/en not_active IP Right Cessation
- 2002-03-05 DK DK02722184T patent/DK1373255T3/da active
- 2002-03-05 ES ES02722184T patent/ES2236505T3/es not_active Expired - Lifetime
- 2002-03-11 TW TW091104444A patent/TWI249532B/zh not_active IP Right Cessation
- 2002-03-11 MY MYPI20020866A patent/MY124838A/en unknown
- 2002-03-11 AR ARP020100873A patent/AR035944A1/es active IP Right Grant
- 2002-05-03 UA UA2003087776A patent/UA74871C2/uk unknown
-
2003
- 2003-09-10 IL IL157839A patent/IL157839A/en unknown
- 2003-09-10 NO NO20034003A patent/NO324954B1/no not_active IP Right Cessation
- 2003-09-11 ZA ZA200307117A patent/ZA200307117B/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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