ATE299711T1 - Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen - Google Patents

Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen

Info

Publication number
ATE299711T1
ATE299711T1 AT98918742T AT98918742T ATE299711T1 AT E299711 T1 ATE299711 T1 AT E299711T1 AT 98918742 T AT98918742 T AT 98918742T AT 98918742 T AT98918742 T AT 98918742T AT E299711 T1 ATE299711 T1 AT E299711T1
Authority
AT
Austria
Prior art keywords
tolerance
mucosatal
compositions containing
immunological tolerance
binding compounds
Prior art date
Application number
AT98918742T
Other languages
English (en)
Inventor
Jacob Sten Petersen
Original Assignee
Jacob Sten Petersen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jacob Sten Petersen filed Critical Jacob Sten Petersen
Application granted granted Critical
Publication of ATE299711T1 publication Critical patent/ATE299711T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55544—Bacterial toxins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/868—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, or immunotolerance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98918742T 1997-04-23 1998-04-23 Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen ATE299711T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4418297P 1997-04-23 1997-04-23
US4418497P 1997-04-23 1997-04-23
PCT/US1998/008361 WO1998047529A1 (en) 1997-04-23 1998-04-23 Combinations of antigen and mucosal binding component for inducing specific immunological tolerance

Publications (1)

Publication Number Publication Date
ATE299711T1 true ATE299711T1 (de) 2005-08-15

Family

ID=26721263

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98918742T ATE299711T1 (de) 1997-04-23 1998-04-23 Immunologische toleranz induzierende zusammensetzungen enthaltend antigen und mukosale bindende verbindungen

Country Status (8)

Country Link
US (1) US7097845B2 (de)
EP (1) EP0977586B1 (de)
JP (1) JP2001523249A (de)
AT (1) ATE299711T1 (de)
AU (1) AU7161098A (de)
DE (1) DE69830900T2 (de)
DK (1) DK0977586T3 (de)
WO (1) WO1998047529A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800487D0 (en) * 1998-01-09 1998-03-04 Oratol Limited Therapies
AU7404800A (en) * 1999-09-30 2001-04-30 Novo Nordisk A/S A method for preparing conjugates between an antigen and mucosal binding component
JP2003520825A (ja) * 2000-01-25 2003-07-08 ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・ネブラスカ 抗ドナー免疫へ抵抗する、移植前に順応された臓器
US7897575B2 (en) * 2000-05-24 2011-03-01 The United States Of America As Represented By The Department Of Health And Human Services Treatment and prevention of vascular dementia
CA2447795A1 (en) * 2001-05-23 2002-11-28 Duotol Ab Suppression of allergic reactions by transdermal administration of allergens in conjunction with or conjugated to toxin subunits or fragments thereof
CA2531988C (en) 2003-08-05 2016-06-28 Novo Nordisk A/S Novel insulin derivatives
ES2371361T3 (es) 2005-12-28 2011-12-30 Novo Nordisk A/S Composiciones que comprenden una insulina acilada y zinc y método de producción de dichas composiciones.
JP5552046B2 (ja) 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー／エス インスリン誘導体を含有する薬学的製剤
JP4959005B2 (ja) 2008-10-30 2012-06-20 ノボ・ノルデイスク・エー／エス 毎日の注射頻度より少ないインスリン注射での真性糖尿病の治療
MX2012012943A (es) * 2010-05-10 2012-11-29 Novo Nordisk As Proceso para preparacion de complejos de insulina-cinc.
DK2632478T3 (da) 2010-10-27 2019-10-07 Novo Nordisk As Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller
EP2991672A1 (de) 2013-04-30 2016-03-09 Novo Nordisk A/S Neuartiges verabreichungsschema
US12605432B2 (en) 2014-06-04 2026-04-21 Diamyd Medical Ab Combinations for antigen based therapy
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation
WO2022177890A1 (en) * 2021-02-16 2022-08-25 Applied Molecular Transport Inc. Solid oral compositions with zinc

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4666837A (en) 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits
AU596961B2 (en) * 1985-03-08 1990-05-24 Takeda Chemical Industries Ltd. Saccharide digestion inhibiting composition
EP0359783B2 (de) 1987-06-24 2002-04-17 Autoimmune, Inc. Behandlung von autoimmun-erkrankungen durch orale verabreichung von autoantigenen
US5399347A (en) 1987-06-24 1995-03-21 Autoimmune, Inc. Method of treating rheumatoid arthritis with type II collagen
JPH02235823A (ja) 1989-03-09 1990-09-18 Watanabe Mitsuko 抗アレルギー剤
JP2891485B2 (ja) 1989-09-25 1999-05-17 科学技術振興事業団 移植拒絶反応抑制剤
CA2070281C (en) 1989-12-20 2005-08-23 David Allen Hafler Improved treatment of autoimmune diseases by aerosol administration of auto antigens
AU651097B2 (en) 1990-03-02 1994-07-14 Autoimmune, Inc. Enhancement of the down-regulation of autoimmune diseases by oral administration of autoantigens
JP3198390B2 (ja) * 1990-09-03 2001-08-13 武田薬品工業株式会社 経粘膜用製剤
CA2050425A1 (en) 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
IL99864A (en) 1990-10-31 2000-11-21 Autoimmune Inc Compositions for suppressing transplant rejection in mammals which contain tissue donor derived MHC antigens
HU220357B (hu) 1992-02-28 2001-12-28 Autoimmune Inc. Eljárás és készítmények autoimmun betegségek kezelésére bystander antigén alkalmazásával
US5453272A (en) 1992-10-02 1995-09-26 Alberta Research Council Lectin derived carbohydrate binding-peptide
JP3109328B2 (ja) 1993-05-19 2000-11-13 ウシオ電機株式会社 加熱定着装置
EP0705108A4 (de) 1993-06-02 1997-08-06 Tvw Telethon Inst Child Health Verwendung von kryptischen peptiden zur induktion immunologisches toleranz
US5681571A (en) * 1993-10-08 1997-10-28 Duotol Ab Immunological tolerance-inducing agent
JP2847696B2 (ja) * 1994-05-11 1999-01-20 田辺製薬株式会社 プロピオフェノン誘導体及びその製法
JP2847695B2 (ja) * 1994-05-11 1999-01-20 田辺製薬株式会社 血糖降下剤
IL111866A (en) 1994-12-04 2005-03-20 Yeda Res & Dev Pharmaceutical compositions comprising the b-oligomer of pertussis toxin
WO1996021458A1 (en) 1995-01-10 1996-07-18 Fibrogen, Inc. Collagen-based methods and formulations for the treatment of immune system-mediated diseases
AU6113896A (en) 1995-06-05 1996-12-24 Brigham And Women's Hospital Use of oral tolerance to suppress both th1 and th2 immune re sponses and to suppress antibody production
GB9513733D0 (en) * 1995-07-05 1995-09-06 Univ Bristol Therapeutic agents

Also Published As

Publication number Publication date
DE69830900T2 (de) 2006-05-24
US20020119159A1 (en) 2002-08-29
AU7161098A (en) 1998-11-13
EP0977586B1 (de) 2005-07-20
DE69830900D1 (de) 2005-08-25
WO1998047529A1 (en) 1998-10-29
JP2001523249A (ja) 2001-11-20
DK0977586T3 (da) 2005-12-05
US7097845B2 (en) 2006-08-29
EP0977586A1 (de) 2000-02-09

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