ATE301131T1 - Gegen gastrointestinale transport rezeptoren gerichtete retro-invertierte peptide und deren verwendung - Google Patents
Gegen gastrointestinale transport rezeptoren gerichtete retro-invertierte peptide und deren verwendungInfo
- Publication number
- ATE301131T1 ATE301131T1 AT99972640T AT99972640T ATE301131T1 AT E301131 T1 ATE301131 T1 AT E301131T1 AT 99972640 T AT99972640 T AT 99972640T AT 99972640 T AT99972640 T AT 99972640T AT E301131 T1 ATE301131 T1 AT E301131T1
- Authority
- AT
- Austria
- Prior art keywords
- retro
- inverted
- inverted peptides
- drug
- targeted against
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 230000002496 gastric effect Effects 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 238000001727 in vivo Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011859 microparticle Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 230000001839 systemic circulation Effects 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6425—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a receptor, e.g. CD4, a cell surface antigen, i.e. not a peptide ligand targeting the antigen, or a cell surface determinant, i.e. a part of the surface of a cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10903898P | 1998-11-19 | 1998-11-19 | |
| PCT/IE1999/000117 WO2000031123A2 (en) | 1998-11-19 | 1999-11-19 | Retro-inversion peptides that target gastro-intestinal tract transport receptors and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE301131T1 true ATE301131T1 (de) | 2005-08-15 |
Family
ID=22325486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99972640T ATE301131T1 (de) | 1998-11-19 | 1999-11-19 | Gegen gastrointestinale transport rezeptoren gerichtete retro-invertierte peptide und deren verwendung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7491796B1 (de) |
| EP (1) | EP1131344B1 (de) |
| JP (1) | JP4566406B2 (de) |
| AT (1) | ATE301131T1 (de) |
| AU (1) | AU1174400A (de) |
| CA (1) | CA2349290A1 (de) |
| DE (1) | DE69926531T2 (de) |
| WO (1) | WO2000031123A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1131344B1 (de) * | 1998-11-19 | 2005-08-03 | ELAN CORPORATION, Plc | Gegen gastrointestinale transport rezeptoren gerichtete retro-invertierte peptide und deren verwendung |
| AUPR272901A0 (en) * | 2001-01-25 | 2001-02-22 | Gainful Plan Limited | Method of preparing biological materials and preparations produced using same |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| GB0501741D0 (en) * | 2005-01-27 | 2005-03-02 | Binding Site The Ltd | Antibody |
| WO2013016223A2 (en) * | 2011-07-22 | 2013-01-31 | The University Of Chicago | Treatments for migraine and related disorders |
| PL2897620T3 (pl) | 2012-09-21 | 2020-11-02 | Intensity Therapeutics, Inc | Sposób leczenia nowotworu złośliwego |
| US12324827B2 (en) | 2019-09-09 | 2025-06-10 | The University Of Chicago | Combination therapy for the treatment of migraines |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT71860A (en) * | 1992-08-27 | 1996-02-28 | Deakin Res Ltd | Retro-, inverso-, and retro-inverso synthetic peptide analogues |
| AU705688B2 (en) * | 1995-11-10 | 1999-05-27 | Cytogen Corporation | Peptides which enhance transport across tissues and methods of identifying and using the same |
| US6361938B1 (en) * | 1996-11-08 | 2002-03-26 | Elan Corporation, Plc | Peptides which enhance transport across tissues and methods of identifying and using the same |
| JP4129298B2 (ja) * | 1997-05-15 | 2008-08-06 | サイトジェン コーポレーション | 胃腸管（ｇｉｔ）輸送受容体に結合するランダムペプチド、及び関連した方法 |
| US6703362B1 (en) * | 1997-05-15 | 2004-03-09 | Cytogen Corporation | Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods |
| EP1131344B1 (de) * | 1998-11-19 | 2005-08-03 | ELAN CORPORATION, Plc | Gegen gastrointestinale transport rezeptoren gerichtete retro-invertierte peptide und deren verwendung |
-
1999
- 1999-11-19 EP EP99972640A patent/EP1131344B1/de not_active Expired - Lifetime
- 1999-11-19 CA CA002349290A patent/CA2349290A1/en not_active Abandoned
- 1999-11-19 US US09/443,986 patent/US7491796B1/en not_active Expired - Fee Related
- 1999-11-19 AU AU11744/00A patent/AU1174400A/en not_active Abandoned
- 1999-11-19 AT AT99972640T patent/ATE301131T1/de not_active IP Right Cessation
- 1999-11-19 DE DE69926531T patent/DE69926531T2/de not_active Expired - Lifetime
- 1999-11-19 WO PCT/IE1999/000117 patent/WO2000031123A2/en not_active Ceased
- 1999-11-19 JP JP2000583950A patent/JP4566406B2/ja not_active Expired - Fee Related
-
2009
- 2009-01-21 US US12/356,646 patent/US20090238886A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4566406B2 (ja) | 2010-10-20 |
| EP1131344B1 (de) | 2005-08-03 |
| WO2000031123A2 (en) | 2000-06-02 |
| US20090238886A1 (en) | 2009-09-24 |
| US7491796B1 (en) | 2009-02-17 |
| DE69926531D1 (de) | 2005-09-08 |
| CA2349290A1 (en) | 2000-06-02 |
| EP1131344A2 (de) | 2001-09-12 |
| JP2002530429A (ja) | 2002-09-17 |
| DE69926531T2 (de) | 2006-03-30 |
| WO2000031123A3 (en) | 2000-11-09 |
| AU1174400A (en) | 2000-06-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |