DK0949907T3 - Fremgangsmåder og præparater til forbedret biotilgængelighed og biologisk aktive midler til slimhindeadministration - Google Patents

Fremgangsmåder og præparater til forbedret biotilgængelighed og biologisk aktive midler til slimhindeadministration

Info

Publication number
DK0949907T3
DK0949907T3 DK97950343T DK97950343T DK0949907T3 DK 0949907 T3 DK0949907 T3 DK 0949907T3 DK 97950343 T DK97950343 T DK 97950343T DK 97950343 T DK97950343 T DK 97950343T DK 0949907 T3 DK0949907 T3 DK 0949907T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
biologically active
active agents
mucosal administration
Prior art date
Application number
DK97950343T
Other languages
English (en)
Inventor
Jaap Kampinga
Bruce Joseph Roser
Camilo Colaco
Ian Sanderson
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Application granted granted Critical
Publication of DK0949907T3 publication Critical patent/DK0949907T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK97950343T 1996-12-31 1997-12-31 Fremgangsmåder og præparater til forbedret biotilgængelighed og biologisk aktive midler til slimhindeadministration DK0949907T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3397696P 1996-12-31 1996-12-31
PCT/GB1997/003557 WO1998029097A1 (en) 1996-12-31 1997-12-31 Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery

Publications (1)

Publication Number Publication Date
DK0949907T3 true DK0949907T3 (da) 2003-07-14

Family

ID=21873566

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97950343T DK0949907T3 (da) 1996-12-31 1997-12-31 Fremgangsmåder og præparater til forbedret biotilgængelighed og biologisk aktive midler til slimhindeadministration

Country Status (12)

Country Link
US (1) US6517860B1 (da)
EP (1) EP0949907B1 (da)
JP (1) JP2001507357A (da)
AT (1) ATE234607T1 (da)
AU (1) AU732347B2 (da)
CA (1) CA2275502A1 (da)
DE (1) DE69720045T2 (da)
DK (1) DK0949907T3 (da)
ES (1) ES2192705T3 (da)
PT (1) PT949907E (da)
WO (1) WO1998029097A1 (da)
ZA (1) ZA9711732B (da)

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Also Published As

Publication number Publication date
EP0949907A1 (en) 1999-10-20
DE69720045D1 (de) 2003-04-24
PT949907E (pt) 2003-07-31
US6517860B1 (en) 2003-02-11
ZA9711732B (en) 1998-12-28
ATE234607T1 (de) 2003-04-15
AU732347B2 (en) 2001-04-26
JP2001507357A (ja) 2001-06-05
WO1998029097A1 (en) 1998-07-09
ES2192705T3 (es) 2003-10-16
EP0949907B1 (en) 2003-03-19
DE69720045T2 (de) 2003-09-04
CA2275502A1 (en) 1998-07-09
AU5333898A (en) 1998-07-31

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