ATE302021T1 - Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52 - Google Patents

Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52

Info

Publication number
ATE302021T1
ATE302021T1 AT98901044T AT98901044T ATE302021T1 AT E302021 T1 ATE302021 T1 AT E302021T1 AT 98901044 T AT98901044 T AT 98901044T AT 98901044 T AT98901044 T AT 98901044T AT E302021 T1 ATE302021 T1 AT E302021T1
Authority
AT
Austria
Prior art keywords
freeze
human
dried composition
bone protein
morphogenic bone
Prior art date
Application number
AT98901044T
Other languages
English (en)
Inventor
Mitsuko Inagaki
Hideki Ichikawa
Original Assignee
Bioph Biotech Entw Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioph Biotech Entw Pharm Gmbh filed Critical Bioph Biotech Entw Pharm Gmbh
Application granted granted Critical
Publication of ATE302021T1 publication Critical patent/ATE302021T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98901044T 1997-01-30 1998-01-29 Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52 ATE302021T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1634997 1997-01-30
PCT/JP1998/000371 WO1998033514A1 (en) 1997-01-30 1998-01-29 Freeze-dried composition of bone morphogenetic protein human mp52

Publications (1)

Publication Number Publication Date
ATE302021T1 true ATE302021T1 (de) 2005-09-15

Family

ID=11913900

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98901044T ATE302021T1 (de) 1997-01-30 1998-01-29 Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52

Country Status (22)

Country Link
EP (1) EP0972520B9 (de)
JP (1) JP4209948B2 (de)
KR (1) KR100548107B1 (de)
CN (1) CN1152712C (de)
AP (1) AP983A (de)
AT (1) ATE302021T1 (de)
AU (1) AU737595B2 (de)
BR (1) BR9807537B1 (de)
CA (1) CA2278546C (de)
DE (1) DE69831223T9 (de)
DK (1) DK0972520T3 (de)
EA (1) EA001579B1 (de)
ES (1) ES2244043T3 (de)
HU (1) HU226554B1 (de)
IL (2) IL130967A0 (de)
NO (1) NO322334B1 (de)
NZ (1) NZ336509A (de)
PL (1) PL189381B1 (de)
RS (1) RS49691B (de)
SI (1) SI0972520T1 (de)
TR (1) TR199901832T2 (de)
WO (1) WO1998033514A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6267798A (en) † 1997-02-07 1998-08-26 Stryker Corporation Matrix-free osteogenic devices, implants and methods of use thereof
US20050053596A1 (en) * 2001-10-09 2005-03-10 Stringer Bradley Michael John Therapeutic biological product and method for formation of new vascularised bone
ATE303169T1 (de) 2001-11-19 2005-09-15 Scil Technology Gmbh Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
CN100522241C (zh) 2002-09-10 2009-08-05 Scil技术股份有限公司 在低氧气浓度下用骨诱导蛋白包被的金属植入物
WO2005011739A1 (en) * 2003-08-05 2005-02-10 Fuji Photo Film B.V. Use of recombinant or synthetic gelatin as a stabiliser in vaccines
AU2004288854B2 (en) * 2003-11-10 2009-10-01 Arriva-Pharmaceuticals, Inc. Dry recombinant human alpha 1-antitrypsin formulation
WO2005089829A2 (en) 2004-03-10 2005-09-29 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
US10216709B2 (en) 2015-05-22 2019-02-26 Microsoft Technology Licensing, Llc Unified messaging platform and interface for providing inline replies
US20160344677A1 (en) 2015-05-22 2016-11-24 Microsoft Technology Licensing, Llc Unified messaging platform for providing interactive semantic objects

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0080879B1 (de) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Stabilisiertes Interferon enthaltende pharmazeutische Zusammensetzung
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
DK0591392T3 (da) * 1991-06-21 1996-09-30 Genetics Inst Farmaceutiske formuleringer af osteogene proteiner
JP2966592B2 (ja) * 1991-07-20 1999-10-25 萩原 義秀 安定化されたヒトモノクローナル抗体製剤
CA2129820C (en) * 1992-02-12 2003-06-17 Helge Neidhardt Dna sequences encoding novel growth/differentiation factors
CA2093836A1 (en) * 1992-04-24 1993-10-25 Wayne Gombotz Biodegradable tgf-.beta. delivery system for bone regeneration
DE4239877C1 (de) * 1992-11-27 1994-03-17 Boehringer Ingelheim Int Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
DE69524456T2 (de) * 1995-03-21 2002-08-01 Applied Research Systems Flüssige hcg-formulierungen
PT955313E (pt) * 1995-04-19 2006-07-31 Bioph Biotech Entw Pharm Gmbh Nova proteina e processo para a sua producao

Also Published As

Publication number Publication date
JP4209948B2 (ja) 2009-01-14
EA199900694A1 (ru) 2000-04-24
AP983A (en) 2001-07-16
PL189381B1 (pl) 2005-07-29
PL334852A1 (en) 2000-03-27
CN1152712C (zh) 2004-06-09
NO322334B1 (no) 2006-09-18
NZ336509A (en) 2001-03-30
NO993702L (no) 1999-09-29
HUP0002386A2 (hu) 2000-11-28
DE69831223T2 (de) 2006-02-16
AP9901602A0 (en) 1999-09-30
EA001579B1 (ru) 2001-06-25
DE69831223D1 (de) 2005-09-22
AU5679198A (en) 1998-08-25
EP0972520B1 (de) 2005-08-17
WO1998033514A1 (en) 1998-08-06
IL130967A (en) 2006-12-10
TR199901832T2 (xx) 1999-12-21
EP0972520B9 (de) 2006-03-22
CA2278546A1 (en) 1998-08-06
BR9807537B1 (pt) 2009-01-13
CA2278546C (en) 2008-04-01
HUP0002386A3 (en) 2002-09-30
IL130967A0 (en) 2001-01-28
ES2244043T3 (es) 2005-12-01
EP0972520A4 (de) 2002-11-05
YU34999A (sh) 2002-08-12
AU737595B2 (en) 2001-08-23
SI0972520T1 (sl) 2006-02-28
DE69831223T9 (de) 2006-12-07
KR20000070586A (ko) 2000-11-25
RS49691B (sr) 2007-12-31
CN1244127A (zh) 2000-02-09
BR9807537A (pt) 2000-03-21
EP0972520A1 (de) 2000-01-19
HU226554B1 (en) 2009-03-30
KR100548107B1 (ko) 2006-02-02
NO993702D0 (no) 1999-07-29
DK0972520T3 (da) 2005-12-19

Similar Documents

Publication Publication Date Title
FR2751202B1 (fr) Implant squelettique
DE69715264D1 (de) Knochenprothese
AU3866097A (en) Naphtholactams and lactones as bone morphogenetic protein active agents
FI990596L (fi) Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset
EP1100869A4 (de) 98 menschliche sekretierte proteine
MA26545A1 (fr) Procedes de cicatrisation des os
FI960809A7 (fi) Hermoregeneraatio käyttäen ihmisen luun morfogeneettisiä proteiineja
DE69624672D1 (de) Wirbelsäulenimplantat
BR9900685B1 (pt) composição sólida desodorante e utilização cosmética de uma composição sólida.
BR9604872A (pt) Composição para tratamento de cabelo
PT875252E (pt) Formulacoes de proteina c activada
NO965208D0 (no) Benprotese
EP1095159A4 (de) Knochenmorphogenese-protein
PT907364E (pt) Composicao farmaceutica de libertacao sustida
EP1040117A4 (de) 110 menschliche sekretierte proteines
BR9707151A (pt) Conjunto de aplicação de um produto e conjunto aplicador de um desodorante corporal
EP0906077A4 (de) Hautpflegemittel
FR2760189B1 (fr) Composition de traitement capillaire
EP1044211A4 (de) 36 menschliche sekretierte proteine
EP1124850A4 (de) 12 menschliche sekretierte proteine
DE69831223D1 (de) Gefriergetrocknete zusammensetzung des menschlichen,morphogenen knochenproteins mp52
FR2767062B1 (fr) Composition comprenant de la propolis
EP1012262A4 (de) Menschliches frezzeled-ähnliches protein
NO980375D0 (no) Humant MP52 Arg protein
FI971872A0 (fi) Proteiinikoostumus ja sen valmistus ja käyttö sekä sitä sisältävät valmisteet ja näiden valmistus

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0972520

Country of ref document: EP